Obesity Is Associated with Early Onset of Gastrointestinal Cancers in California by Yen-Yi Juo, Melinda A. Maggard Gibbons, Erik Dutson, Anne Y. Lin, Jane Yanagawa, O. Joe Hines, Guido Eibl, Yijun Chen

“…The diagnosis of obesity (BMI > 30) was associated with a reduction in diagnosis age across all four cancer types: 3.25 ± 0.53 years for gastric cancer, 4.56 ± 0.18 years for colorectal cancer, 4.73 ± 0.73 years for esophageal cancer, and 5.35 ± 0.72 for pancreatic cancer. The diagnosis of morbid obesity (BMI > 40) was associated with a more pronounced reduction in the age of diagnosis: 5.48 ± 0.96 years for gastric cancer, 7.75 ± 0.30 years for colorectal cancer, 7.67 ± 1.26 years for esophageal cancer, and 8.19 ± 1.25 years for pancreatic cancer. …”
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Nummular retinal pigment epithelium loss in bilateral diffuse uveal melanocytic proliferation by Neha Goel

“…A 71-year-old male with pancreatic cancer exhibited multiple hypopigmented patches on fundus examination, with corresponding transmission defects on fluorescein angiography and outer retinal and RPE loss on optical coherence tomography, confirming RPE loss as the predominant feature. …”
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Gastrointestinal Bleeding due to Pancreatic Disease-Related Portal Hypertension by Kexin Zheng, Xiaozhong Guo, Ji Feng, Zhaohui Bai, Xiaodong Shao, Fangfang Yi, Yongguo Zhang, Rui Zhang, Han Liu, Fernando Gomes Romeiro, Xingshun Qi

“…Three elderly patients (>60 years old) were diagnosed with pancreatic cancer, of whom one underwent laparoscopic radical distal pancreatectomy and splenectomy, one received chemotherapy, and another one chose conservative management due to multiple systemic metastases. …”
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Cancer of the Pancreas: The Best Image for Early Detection – CT, MRI, PET or US? by Anthony E Hanbidge

“…Pancreatic cancer has a poor prognosis, and the best chance for survival is to diagnose the tumour at an early stage. …”
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Incidence and risk of endocrine and metabolic abnormalities linked to PARP inhibitors in solid tumors: a meta-analysis by Shunlian Fu, Pingjin Zou, Zengyi Fang, Xinxiang Zhou, Junyang Chen, Cuicui Gong, Li Quan, Bing Lin, Qiu Chen, Jinyi Lang, Meihua Chen

“…Niraparib demonstrated an increased risk of any-grade hyperglycemia (OR = 2.15, 95% CI 1.28–3.62), with patients receiving PARPi for metastatic pancreatic cancer showing a higher susceptibility to any-grade hyperglycemia (OR = 1.78, 95% CI 1.04–3.04). …”
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Pancreatic Myeloid Sarcoma Causing Obstructive Jaundice: A Case Report and Literature Review by Laura E. Lavette, Angela G. Niehaus, Clancy J. Clark, Jason D. Conway, Girish Mishra, Darius A. Jahann

“…Isolated cases of pancreatic MS have been known to progress to AML; therefore, it is crucial to differentiate MS from more common diagnoses, such as pancreatic cancer or pancreatitis. This is a case of a 70-year-old male with symptomatic obstructive jaundice secondary to pancreatic MS, ultimately requiring endoscopic ultrasound (EUS) and endoscopic retrograde cholangiopancreatography (ERCP) for diagnosis and management. …”
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Synthetic CB1 Cannabinoids Promote Tunneling Nanotube Communication, Cellular Migration, and Epithelial–Mesenchymal Transition in Pancreatic PANC-1 and Colorectal SW-620 Cancer Cel... by David A. Bunsick, Leili Baghaie, Yunfan Li, Abdulrahman M. Yaish, Emilyn B. Aucoin, Elizabeth Skapinker, Rashelle Aldbai, Myron R. Szewczuk

“…To assess the key survival pathways critical for pancreatic cancer progression, we used the AlamarBlue assay to determine synthetic CB1 cannabinoids to induce the cell’s metabolic viability drivers to stage migratory intercellular communication. …”
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Clinical observations of patients with metastatic castration-resistant prostate cancer living in the Tambov region by P. G. Berezin, V. V. Milovanov, A. A. Ivannikov, V. A. Kuleshkov, K. M. Nyushko

“…Administration of 1st-line treatment regimens stabilizes the disease in the majority of pancreatic cancer patients; in some cases, the disease becomes aggressive, distant metastases appear, most oſten in bones, lymph nodes, and internal organs, as demonstrated by three clinical observations presented in this article. …”
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Endoscopic Management of a Proximally Migrated Fully Covered SEMS Using the Stent-in-Stent Technique by Arunchai Chang, Varayu Prachayakul

“…We present a case of a 67-year-old woman who had locally advanced pancreatic cancer and developed a common bile duct obstruction. …”
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Advances in nucleic acid-based cancer vaccines by Hung-Chun Liao, Shih-Jen Liu

“…In oncology, the combination of mRNA vaccine encoding neoantigens and immune checkpoint inhibitors (ICIs) has shown remarkable efficacy in eliciting protective responses against diseases like melanoma and pancreatic cancer. Although the use of a COVID-19 DNA vaccine has been limited to India, the inherent stability at room temperature and cost-effectiveness of DNA vaccines present a viable option that could benefit developing countries. …”
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A Review on the Antimutagenic and Anticancer Effects of Cysteamine by Chun-Man Lee

“…The efficacy of cysteamine has been shown in vitro and in vivo for the treatment of different types of cancer, such as gastrointestinal cancer, pancreatic cancer, sarcomas, hepatocellular carcinoma, and melanoma, leading to the significant reduction of lesions and/or the increase of survival time. …”
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Biological Properties and the Role of IL-25 in Disease Pathogenesis by Yuwan Liu, Zewei Shao, Guoqiang Shangguan, Qingli Bie, Bin Zhang

“…By contrast, IL-17B is reported to be closely related to certain diseases, particularly tumors such as breast cancer, gastric cancer, and pancreatic cancer. Recently, the biological function of IL-17E (also called IL-25) in disease, particularly airway diseases, has attracted the attention of researchers. …”
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Morbidity and Mortality Rates from Digestive Diseases in the RF Northwestern Federal District (NWFD) and Measures to Reduce Them by Andrey Yu. Baranovsky, Alexey M. Belyaev, Elina A. Kondrashina

“…Along with a decrease in the incidence of gastric cancer, an increase in the incidence of colorectal cancer, as well as pancreatic cancer, is observed. A decrease in mortality from all the aforementioned cancer localizations is revealed.Conclusions. …”
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Long-Term Survival in Locally Advanced KRAS Wild-Type Pancreatic Adenocarcinoma by Marion Alhenc-Gelas, Romain Cohen, Pascale Cervera, Jean-Christophe Vaillant, Thierry André

“…For locally advanced pancreatic cancer (LAPC), median overall survival is approximately 16 months. …”
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Paraduodenal Pancreatitis: A Deceptive Abdominal Mass with Unique Histologic Findings by Jonathan Zadeh, Anthony Andreoni, Christopher Febres-Aldana, Kritika Krishnamurthy, Jyotsna Kochiyil, Cristina Vincentelli, Kfir Ben-David

“…Diagnosis of this inflammatory process is challenging as its clinical presentation is similar to that of pancreatic cancer. Currently, no definitive radiologic or pathologic features have been established to permit diagnosis of PP without surgical resection. …”
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TRPM7 and TRPM8 Ion Channels in Pancreatic Adenocarcinoma: Potential Roles as Cancer Biomarkers and Targets by Nelson S. Yee, Ada S. Chan, Julian D. Yee, Rosemary K. Yee

“…We are currently investigating the mechanisms which mediate the functional roles of TRPM7 and TRPM8 and attempting to develop these ion channels as clinical biomarkers and therapeutic targets for achieving the goal of personalized therapy in pancreatic cancer.…”
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Successful Gastric Volvulus Reduction and Gastropexy Using a Dual Endoscope Technique by Laith H. Jamil, Brian L. Huang, David C. Kunkel, Vijay Jayaraman, Edy E. Soffer

“…An 83-year-old female with a history of pancreatic cancer status postpylorus-preserving Whipple procedure presented with a cecal volvulus requiring right hemicolectomy. …”
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Technical Aspects of Laparoscopic Distal Pancreatectomy for Benign and Malignant Disease: Review of the Literature by T. de Rooij, R. Sitarz, O. R. Busch, M. G. Besselink, M. Abu Hilal

“…The radical antegrade modular pancreatosplenectomy has become mainstay for treating pancreatic cancer and can be performed laparoscopically as well. …”
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Predictive role of the prognostic nutritional index for long-term prognosis among patients undergoing pancreatoduodenectomy: a meta-analysis by Ying Liu, Keyu Li

“…Subgroup analysis stratified by country (China vs. non-China), type of cancer (pancreatic cancer vs. nonpancreatic cancer vs. mixed) and source of HR (univariate vs. multivariate analysis) revealed similar results. …”
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Pancreatic Metastasis of High-Grade Papillary Serous Ovarian Carcinoma Mimicking Primary Pancreas Cancer: A Case Report by Yusuf Gunay, Ebru Demiralay, Alp Demirag

“…It was considered as primary mid portion of pancreatic cancer and a distal pancreatectomy was performed. …”
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