The Role of Insulin, Insulin Growth Factor, and Insulin-Degrading Enzyme in Brain Aging and Alzheimer's Disease by Claude Messier, Kevin Teutenberg

“…Most brain insulin comes from the pancreas and is taken up by the brain by what appears to be a receptor-based carrier. …”
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Immune Responses to Tissue-Restricted Nonmajor Histocompatibility Complex Antigens in Allograft Rejection by Ankit Bharat, T. Mohanakumar

“…It is now established that T-cells reactive to SAgs present in certain organs (e.g., lungs, pancreas, and intestine) are incompletely eliminated, and the dysregulation of peripheral immuneregulation can generate immune responses to SAgs. …”
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The Nrf2/Keap1/ARE Pathway and Oxidative Stress as a Therapeutic Target in Type II Diabetes Mellitus by Joshua A. David, William J. Rifkin, Piul S. Rabbani, Daniel J. Ceradini

“…There is accumulating evidence that this pathway is implicated in diabetic damage to the pancreas, heart, and skin, among other cell types and tissues. …”
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Splenic infarction following torsion of wandering spleen involving pancreatic tail successfully managed in resource limited setting: a case report by Abel Gashaw Wubie, Berhanu Yirga, Martha H. Goedert

“…Torsion involving the distal pancreas is even more unusual. Although patient presentations can be atypical, early diagnosis and prompt intervention can lead to successful outcomes. …”
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Hypoglycemic Activity of Aqueous Root Bark Extract Zanthoxylum chalybeum in Alloxan-Induced Diabetic Rats by Moses Solomon Agwaya, Peter California Vuzi, Agnes Masawi Nandutu

“…The present study evaluated the effect of aqueous root bark extract of Zanthoxylum chalybeum on oral glucose tolerance and pancreas histopathology in alloxanized rats. Method. …”
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Investigating the Effect of Solanum lycopersicum L. (Tomato) Pomace on Growth Performance and some Blood Indices of Broiler Chickens by Meta-Analysis Method by Zahra Sahragard, seyyed javad Hosseini-vashan, Hossein Naeemipour Younesi, Seyyed Homayon Farhangfar

“…The effect of inclusion of tomato pomace on weight gain during the growth period, feed intake in all periods and FCR in the starter, grower, and finisher period, the blood concentration of triglyceride, glucose, and the percentage of abdominal fat, liver, heart, pancreas and gall bladder, also breast was not significantly affected by tomato pomace. …”
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Molecular evidence of the inhibitory potential of melatonin against sodium arsenite toxicity by Ramtin Farhadi, Marzieh Daniali, Maryam Baeeri, Reza Khorasani, Hamed Haghi-Aminjan, Mahdi Gholami, Mahban Rahimifard, Mona Navaei-Nigjeh, Mohammad Abdollahi

“…After 28 days of the experiment, the blood and tissue samples of the pancreas were removed for biochemical and pathological examination. …”
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Struggling with a Gastric Volvulus Secondary to a Type IV Hiatal Hernia by Dafnomilis George, Pappas V. Apostolos, Panoutsopoulos Athanasios, Lagoudianakis E. Emmanuel, Koronakis E. Nikolaos, Panagiotopoulos Nikolaos, Seretis Charalampos, Karanikas George, Manouras J. Andreas

“…Type IV hiatal hernias are characterized by herniation of the stomach along with associated viscera such as the spleen, colon, small bowel, and pancreas through the esophageal hiatus. They are relatively rare, representing only about 5%–7% of all hernias, and can be associated with severe complications. …”
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Gut Microbiota-Immune System Crosstalk and Pancreatic Disorders by D. Pagliari, A. Saviano, E. E. Newton, M. L. Serricchio, A. A. Dal Lago, A. Gasbarrini, R. Cianci

“…The alteration of such balance, called dysbiosis, determines an intestinal bacterial overgrowth which leads to the disruption of the intestinal barrier with systemic translocation of pathogens. The pancreas does not possess its own microbiota, and it is believed that inflammatory and neoplastic processes affecting the gland may be linked to intestinal dysbiosis. …”
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Immunoglobulin G4 Sclerosing Cholangitis: An Unusual Cause of Obstructive Jaundice—Case Report and Literature Review by Pragya Shrestha, Brian Le, Brent Wagner, William Pompella, Paras Karmacharya

“…High serum IgG4 levels, characteristic radiological (e.g., sausage-shaped pancreas or periaortitis) or biopsy findings (high percentage of IgG4+ plasma cells, lymphoplasmacytic infiltrate, storiform fibrosis, or obliterative phlebitis) in the setting of these features is diagnostic of this disease process. …”
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IgG4-Related Sclerosing Disease Causing Spinal Cord Compression: The First Reported Case in Literature by Nooraldin Merza, Ahmed Taha, John Lung, Anthony W. Benderman, Stephen E. Wright

“…It is an extremely rare disease that most frequently affects the pancreas causing autoimmune pancreatitis. It can also affect the gallbladder, salivary glands, and lacrimal glands causing respective organ-specific complications. …”
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Optimization of Spectrophotometric and Fluorometric Assays Using Alternative Substrates for the High-Throughput Screening of Lipase Activity by Jun-Young Park, Jisu Ha, Yoonseok Choi, Pahn-Shick Chang, Kyung-Min Park

“…Four model lipases from Chromobacterium viscosum, Pseudomonas fluorescens, Sus scrofa pancreas, and wheat germ (Triticum aestivum) were allowed to hydrolyze the alternative substrates at different substrate concentrations (1–5 mM), operating pH (5.0–8.0), and operating temperatures (25–55°C). …”
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Indocyanine green fluorescence-guided laparoscopic central pancreatectomy for complete pancreatic transection trauma: a rare case and literature review by Xitao Wang, Xiong Teng, Yi Liu, Wei Cheng

“…The patient then underwent emergency laparoscopic central pancreatectomy, during which we used ICG fluoroscopy to assess the blood perfusion of the damaged pancreas to determine the extent of resection. The patient developed a biochemical fistula (grade A pancreatic fistula) after surgery, and no other intervention was performed except for continuous drainage. …”
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Tuberculosis of the thyroid gland: A rare case report by Manisha Kamlesh Galani, Kamlesh Jamnadas Galani, Swati Nileshkumar Lakhani

“…While tuberculosis can affect various organs, its involvement in the thyroid, pancreas, striated, and cardiac muscle is uncommon. …”
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Antihyperglycemic Activity of Houttuynia cordata Thunb. in Streptozotocin-Induced Diabetic Rats by Manish Kumar, Satyendra K. Prasad, Sairam Krishnamurthy, Siva Hemalatha

“…It also significantly reversed all the alterations in biochemical parameters, that is, total lipid profile, blood urea, creatinine, protein, and antioxidant enzymes in liver, pancreas, and adipose tissue of diabetic rats. Furthermore, we have demonstrated that the extract significantly reversed the expression patterns of various glucose homeostatic enzyme genes like GLUT-2, GLUT-4, and caspase-3 levels but did not show any significant effect on PPAR-γ protein expressions. …”
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Changes in the Intestinal Microbiota in Patients with Chronic Pancreatitis: Systematizing Literature Data by I. V. Maev, A. I. Levchenko, D. N. Andreev

“…The severe CP is associated with impaired synthesis of antimicrobial peptides, bicarbonates, and digestive enzymes by the pancreas, which is a risk factor for dysbiotic changes in the intestinal microbiota, consisting in the development of small intestinal bacterial overgrowth (SIBO) and gut dysbiosis. …”
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Vitamin D Receptor Gene Polymorphisms Influence T1D Susceptibility among Pakistanis by Maryam Mukhtar, Andleeb Batool, Abdul Wajid, Iram Qayyum

“…The vitamin D receptor (VDR) gene regulates insulin secretion from the pancreas and acts as a mediator of the immune response through vitamin D. …”
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Statin Induced Changes in Rat Pancreatic Tissue: A Histological and Biochemical Perspective by Abdullah Qamar, Hammad Gul Khan, Muhammad Marghoob Khan, Muhammad Rizwan Bashir Kiani, Hina Kundi, Fareeha Mushtaq

“…At the end of the experiment, the rats were euthanized, and their pancreas was collected for analysis and examined using gold-standard histological parameters including inflammation and fatty infiltration. …”
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Successful Localization of the Source of Hemorrhage in Patient with Post-Whipple Surgery by 99mTc-Labelled Red Blood Cell Scintigraphy by Ahmed Fathala, Alaa Alduraibi, Moheieldin M. Abouzied

“…Whipple pancreatoduodenectomy is most often performed for tumors of the head of the pancreas. Pancreatoduodenectomy has 30%–40% morbidity and mortality, and while post-pancreatoduodenectomy hemorrhage is seen in less than 10% of patients, it accounts for 11%–38% mortality. …”
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General Approach to Identifying Potential Targets for Cancer Imaging by Integrated Bioinformatics Analysis of Publicly Available Genomic Profiles by Yongliang Yang, S. James Adelstein, Amin I. Kassis

“…As examples, we obtained lists of potential hits for six common and lethal human tumors in the prostate, breast, lung, colon, ovary, and pancreas. As control tests, a number of well-known cancer imaging targets were detected and confirmed by our study. …”
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