Dentate gyrus norepinephrine ramping facilitates aversive contextual processing by Eric T. Zhang, Grace S. Saglimbeni, Jiesi Feng, Yulong Li, Michael R. Bruchas

Get full text

Development of an Electronic Database for Acute Pain Service Outcomes by Brandy L Love, Louise A Jensen, Donald Schopflocher, Ban CH Tsui

Get full text

Mesotherapy: From Historical Notes to Scientific Evidence and Future Prospects by Massimo Mammucari, Enrica Maggiori, Domenico Russo, Chiara Giorgio, Gianpaolo Ronconi, Paola E Ferrara, Flora Canzona, Luciano Antonaci, Bartolomeo Violo, Renato Vellucci, Domenico Rocco Mediati, Alberto Migliore, Umberto Massafra, Barbara Bifarini, Fabio Gori, Massimo di Carlo, Stefano Brauneis, Teresa Paolucci, Piergiovanni Rocchi, Anna Cuguttu, Raffaele Di Marzo, Alessandro Bomprezzi, Stefania Santini, Manuela Giardini, Anna Rosa Catizzone, Fiammetta Troili, Dario Dorato, Alessandra Gallo, Costanza Guglielmo, Silvia Natoli

Get full text

Applying evidence-based cross-disciplinary concepts helps to explain the heterogeneity in pain, function, and biological measures in individuals with knee pain with/at risk of oste... by Angela M. Mickle, Jared J. Tanner, Udell Holmes, III, Ahmed Rashid, Olivier Barolette, Brittany Addison, Nicola Sambuco, Cynthia Garvan, Song Lai, Christoph Seubert, Siegfried Schmidt, Roland Staud, Jeffrey C. Edberg, David Redden, Burel R. Goodin, Catherine C. Price, Roger B. Fillingim, Kimberly T. Sibille

Get full text

Postoperative Respiratory Impairment Is a Real Risk for Our Patients: The Intensivist’s Perspective by Vidya K. Rao, Ashish K. Khanna

Get full text

The application of procyanidins in diabetes and its complications: a review of preclinical studies by Yongchuang Zhang, Mengna Li, Haoyuan Liu, Yongfu Fan, Huan Huan Liu

Get full text

Non-thermal atmospheric pressure plasma-irradiated cysteine protects cardiac ischemia/reperfusion injury by preserving supersulfides by Akiyuki Nishimura, Tomohiro Tanaka, Kakeru Shimoda, Tomoaki Ida, Shota Sasaki, Keitaro Umezawa, Hiromi Imamura, Yasuteru Urano, Fumito Ichinose, Toshiro Kaneko, Takaaki Akaike, Motohiro Nishida

Get full text

Restorative Neurostimulation Therapy Compared to Optimal Medical Management: A Randomized Evaluation (RESTORE) for the Treatment of Chronic Mechanical Low Back Pain due to Multifid... by Frank Schwab, Nagy Mekhail, Kiran V. Patel, Meredith Langhorst, Robert D. Heros, Jonathan Gentile, Sherif Costandi, Gregory Moore, Christopher Gilmore, Smith Manion, Krishnan Chakravarthy, S. Craig Meyer, Justin V. Bundy, Jordan L. Tate, Rebecca Sanders, Sandeep Vaid, Oszkar Szentirmai, Johnathan Goree, Vikas V. Patel, Jeff Lehmen, Mehul J. Desai, Jason E. Pope, Anthony Giuffrida, Salim Hayek, Sohrab Singh Virk, Richard Paicius, William R. Klemme, Robert Levy, Christopher Gilligan, the RESTORE investigators

Get full text

Identifying biomarker-driven subphenotypes of cardiogenic shock: analysis of prospective cohorts and randomized controlled trialsResearch in context by Sabri Soussi, Tuukka Tarvasmäki, Antoine Kimmoun, Mojtaba Ahmadiankalati, Feriel Azibani, Claudia C. dos Santos, Kevin Duarte, Etienne Gayat, Jacob C. Jentzer, Veli-Pekka Harjola, Benjamin Hibbert, Christian Jung, Lassus Johan, Bruno Levy, Zihang Lu, Patrick R. Lawler, John C. Marshall, Janine Pöss, Malha Sadoune, Alexis Nguyen, Alexandre Raynor, Katell Peoc'h, Holger Thiele, Rebecca Mathew, Alexandre Mebazaa

“…Funding: Dr Sabri Soussi was awarded the Canadian Institutes of Health Research (CIHR) Doctoral Foreign Study Award (DFSA) and the Merit Awards Program (Department of Anesthesiology and Pain Medicine, University of Toronto, Canada) for the current study.…”
Get full text

Advanced Genetic Testing Comes to the Pain Clinic to Make a Diagnosis of Paroxysmal Extreme Pain Disorder by Ashley Cannon, Svetlana Kurklinsky, Kimberly J. Guthrie, Douglas L. Riegert-Johnson

Get full text

Walking with Neuropathic Pain: Paradoxical Shift from Burden to Support? by David J. Kopsky, Jan M. Keppel Hesselink, Roberto Casale

“…This unusual case report discusses two important issues that relate to pain medicine and rehabilitation in patients with painful spinal cord lesions: (1) the presence of wide areas of sensory loss “covered” by the presence of painful sensations and (2) pathological sensations that can be used and integrated in the body schema to create an improved spatiovisual orientation and thus mobility. …”
Get full text

Clinical case. Successful endoscopic treatment of an epiphrenic diverticulum of the esophagus using diverticular peroral endoscopic myotomy (D-POEM) by O Kryvoruk

Get full text

Cryoablation in Chronic Pain Management: A Narrative Review by Sreyashi Naskar, Debesh Bhoi, Wasimul Hoda, Heena Garg

“…This technique has found widespread application in the field of interventional pain medicine in a variety of conditions including chronic postsurgical pain, phantom limb pain (PLP), and cancer pain. …”
Get full text

Case report of endoscopic treatment of sigmoid gallstone ileus by I Molnar, T Shynkaryk, E Prykhodko, V Perepadya

Get full text

Surgery impairs glymphatic activity and cognitive function in aged mice by Kai Chen, Xingyu Du, Melissa A. Chao, Zhongcong Xie, Guang Yang

Get full text

Severe Hypotension, Hypoxia, and Subcutaneous Erythema Induced by Indigo Carmine Administration during Open Prostatectomy by Koichiro Nandate, Bryan B. Voelzke

Get full text

Single-Cell Sequencing Technology in Oncology: Applications for Clinical Therapies and Research by Baixin Ye, Qingping Gao, Zhi Zeng, Creed M. Stary, Zhihong Jian, Xiaoxing Xiong, Lijuan Gu

Get full text

Relief of Urinary Urgency, Hesitancy, and Male Pelvic Pain with Pulse Radiofrequency Ablation of the Pudendal Nerve: A Case Presentation by Christopher Bui, Sanjog Pangarkar, Scott I. Zeitlin

Get full text

Blood biomarkers to identify patients with different intracranial lesion combinations after traumatic brain injury by Pia Koivikko, Ari J. Katila, Riikka SK. Takala, Iftakher Hossain, Teemu M. Luoto, Rahul Raj, Mari Koivisto, Olli Tenovuo, Kaj Blennow, Peter Hutchinson, Henna-Riikka Maanpää, Mehrbod Mohammadian, Virginia F. Newcombe, Jean-Charles Sanchez, Jussi Tallus, Mark van Gils, Henrik Zetterberg, Jussi P. Posti

Get full text

Type I IFN induces long-chain acyl-CoA synthetase 1 to generate a phosphatidic acid reservoir for lipotoxic saturated fatty acids by Shelley Barnhart, Masami Shimizu-Albergine, Eyal Kedar, Vishal Kothari, Baohai Shao, Melissa Krueger, Cheng-Chieh Hsu, Jingjing Tang, Jenny E. Kanter, Farah Kramer, Danijel Djukovic, Vadim Pascua, Yueh-Ming Loo, Lucrezia Colonna, Sadie J. Van den Bogaerde, Jie An, Michael Gale, Jr., Karen Reue, Edward A. Fisher, Sina A. Gharib, Keith B. Elkon, Karin E. Bornfeldt

Get full text