Influence of sacroiliac joint variation on clinical features of axial spondyloarthritis: a comparative analysis by Denis Poddubnyy, Torsten Diekhoff, Sevtap Tugce Ulas, Fabian Proft, Valeria Rios Rodriguez, Judith Rademacher, Juliane Greese, Katharina Ziegeler, Carolina Dominguez Aleixo, Maximilian Lindholz

“…Classification of back pain as inflammatory (=IBP), human leucocyte antigen-B27 positivity, family history, disease activity according to Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), symptom duration, elevated acute phase reactants, peripheral and extramusculoskeletal manifestations were evaluated. …”
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Network relationship between cognitive function and quality of life in community-dwelling older adults: an observational study from Beijing by Yitian Ye, Yichun Zhang, Jiaju Ren, Yanbo Zhu, Yanbo Zhu

“…Concurrently, quality of life was assessed across eight dimensions: physical functioning, role physical, bodily pain, general health, vitality, social functioning, role emotional, and mental health. …”
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The Effect of Blood Flow Restriction Therapy on Shoulder Function Following Shoulder Stabilization Surgery: A Case Series by John H. McGinniss, John S. Mason, Jamie B. Morris, Will Pitt, Erin M. Miller, Michael S. Crowell

“…Statistically significant and clinically meaningful improvements were reported on the Single Assessment Numeric Evaluation (*p* \< 0.001; mean difference, 17.7; CI: 9.4, 25.9) and Shoulder Pain and Disability Index (*p* \< 0.001; mean difference, -31.1; CI: -44.2, -18.0) from six to 12 weeks postoperatively. …”
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Comparing the Effectiveness of Intra-articular Injection with Autologous Platelet-rich Plasma vs Hyaluronic Acid vs Platelet-derived Growth Factors in Early Osteoarthritis of Knee... by Vidya S Konana, Harish S Yallapura, Sriharsha Bettaswamy, Srinivas P Sivaram, Darshan G Thimmegowda

“…Aims: To compare the effectiveness between intra-articular injection (IAI) of autologous platelet-rich plasma (PRP) vs hyaluronic acid (HA) vs activated PRP in primary osteoarthritis (OA) of the knee grades 1 and 2, in terms of pre- and postinjection functional outcome by the Western Ontario and McMaster Universities Arthritis Index (WOMAC) scale, and pre- and postinjection pain by visual analog scale (VAS). Materials and methods: The patients were divided into three groups based on the treatment they received. …”
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Weizmannia coagulans BC99 modulate gut microbiota after Helicobacter pylori eradication: A randomized double-blind placebo-controlled trial by Ying Wu, Shirui Zhai, Caie Wang, Zhouya Bai, Pingping Tian, Shanshan Tie, Yao Wang, Yingjian Zhang, Lina Zhao, Shaobin Gu

“…BC99 reduced GSRS score, particularly the severity of stomach-abdominal pain during hunger symptoms. Additionally, BC99 reduced the disruption of bismuth quadruple therapy on the gut microbiota, particularly significantly increasing the abundance of Prevotella, Bacillus, Candidatus_Saccharimonas and reducing the abundance of Lachnoclostridium, Intestinibacter, Holdemania, Desulfovibrio. …”
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Proximal Hamstring Tendinopathy: A Systematic Review of Interventions by Anthony Michael Nasser, Bill Vicenzino, Alison Grimaldi, Jay Anderson, Adam Ivan Semciw

“…# Background Proximal hamstring tendinopathy affects athletic and non-athletic populations and is associated with longstanding buttock pain. The condition is common in track and field, long distance running and field-based sports. …”
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Ankle Arthrodesis: Epidemiology, Etiology, and Complications in Diabetic vs Nondiabetic Patients Using US Nationwide Inpatient Sample Data by Assil Mahamid MD, David Maman MD, Summer Sofer, Mykhail Pavlenko MD, Amr Mansour MD, Marah Hodruj MD, Yaron Berkovich MD, Eyal Behrbalk MD

“…Background: Ankle arthrodesis (AA), or ankle fusion, is a surgical procedure used to treat severe ankle pathologies, particularly in patients with chronic pain and reduced mobility due to conditions like osteoarthritis, posttraumatic arthritis, and Charcot arthropathy. …”
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Evaluation of Active Intraoperative Nerve Monitoring in Severe Developmental Dysplasia of the Hip Patients Undergoing Total Hip Arthroplasty by Alireza Manafi Rasi, MD, Sina Afzal, Dr., MD, Mojtaba Baroutkoub, MD, Hasan Shakiba, MD, Pooya Kalani, MD, Mehdi Tavassoli, MD, Reza Zarei, MD

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Efficacy of Physiologically Active nutrients in the Treatment of Asthenic Disorders in Patients with Chronic Diffuse Liver Diseases by M. V. Mayevskaya, M. A. Morozova, A. G. Beniashvili, V. D. Lunkov, V. T. Ivashkin

“…As an additional effect, the disappearance of pain in the right hypochondrium was noted in those cases when patients presented this complaint at the time of inclusion in the observation program. …”
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Analysis of factors associated with intercostal neuralgia after osteoporotic thoracic spine fracture and construction of a prediction model by Zhen-Gang Liu, Fan Yang, Peng-fu Li, Qi Song, Gao Wang, Bo-Yin Zhang

“…Results This study included a total of 104 patients based on the presence or absence of intercostal neuralgia.The results of multifactorial logistic regression analysis showed that injured vertebral intervertebral foraminal area (P = 0.0008, regression coefficient estimate 0.0490, 95% confidence interval 0.0219–0.0798, OR = 1.0503), injured vertebral intervertebral foraminal volume (P = 0.0001, regression coefficient value − 0.0028, 95% confidence interval − 0.0044 to -0.0015, OR = 0.9972), and nerve root area (P = 0.0038, regression coefficient estimate=-0.0876, 95% confidence interval − 0.1506 to -0.0309, OR = 0.9161) were independent associated factors.The fatty degeneration ratio have a positive promotional effect on the probability of developing intercostal pain.The area under the ROC curve (AUC) of the prediction model was 0.851, which indicated that the line graph model had a certain degree of predictive validity. …”
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A randomized comparative effectiveness trial to evaluate two programs for promotion of physical activity after spinal cord injury in manual wheelchair users by Jenna M. Martinez, Jenna M. Martinez, Lisa L. Haubert, Valerie J. Eberly, Walter B. Weiss, Jeffery W. Rankin

“…Metabolic bloodwork and shoulder pain scores did not change and were similar between groups.ConclusionDepending on the measure used, these findings suggest that a WODAA approach to PA is comparable or more effective than a traditional PACE program in promoting physical activity in low-active manual wheelchair users with paraplegia.…”
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Occupational adjustments and work ability of young adult cancer survivors: results from the AYA-Leipzig study by Hannah Brock, Katharina Schröter, Michael Friedrich, Annekathrin Sender, Diana Richter, Anja Mehnert-Theuerkauf, Kristina Geue, Katja Leuteritz

“…A fatigue index < 11, elevated levels of pain and the presence of metastases/recurrence were associated with a lower benefit of reduced working hours (R2 = 0.183). …”
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Theranostic nanoemulsions suppress macrophage-mediated acute inflammation in rats by Riddhi Vichare, Yalcin Kulahci, Rebecca McCallin, Fatih Zor, Fatma Nurefsan Selek, Lu Liu, Caitlin Crelli, Anneliese Troidle, Michele Herneisey, James M. Nichols, Andrew J. Shepherd, Vijay S. Gorantla, Jelena M. Janjic

“…Abstract In inflammatory diseases or following an injury, dysregulated inflammation is a common driver of pain and tissue damage. Macrophages are immune cells that contribute to the initiation, maintenance, and resolution of inflammation due to their phenotypic plasticity in response to signals from inflammatory microenvironments. …”
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Is surgery superior for distal ulna fractures? a comprehensive systematic review and meta-analysis by Zakaria Chabihi, Brahim Demnati, Mohamed Moussadiq, Tariq Aalil, Yassine Fath El Khir, El Mehdi Boumediane, Mohamed Amine Benhima, Imad Abkari

“…Conclusions While surgical management may offer a higher union rate, the choice of treatment should be individualized, balancing the potential benefits against the risks of surgery, as ORIF implants are typically associated with higher ulnar-sided pain rates and limited ulnar deviation due to implant prominence. …”
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Pilates exercise in pregnancy: a systematic review and meta-analysis by Yuxuan Li, Heran Lu, Liuwei Zhang, Yijia Ren, Xiaotong Dai, Lin Lin

“…Conclusions This systematic review and meta-analysis demonstrate that Pilates during pregnancy positively influences the shortening of labor duration, improves the newborn’s immediate physiological status, and alleviates labor pain. Trial registration The study was registered on the International Prospective Registry of Systematic Reviews——PROSPERO database (CRD42023393309) on January 30, 2023.…”
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Comparative efficacy of <i>Bifidobacterium bifidum, Bifidobacterium longum, Bifidobacterium infantis, Lactobacillus rhamnosus</i> composition and prucalopride in treatment of const... by V. T. Ivashkin, O. M. Drapkina, A. A. Sheptulin, O. S. Shifrin, Ye. A. Poluektova, S. Yu. Kuchumova

“…Intensity of abdominal pain and meteorism were estimated by visual analog scale (VAS), stool consistency — by Bristol stool form scale, frequency of defecation — by calculation of number of defecations for every week of treatment. …”
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Mid-Term to Long-Term Outcomes of Total Hip Arthroplasty Using a Cementless Trochanteric Sparing Short Stem Through Direct Anterior Approach: A Single-Center Study by Seyed Mohammad Javad Mortazavi, MD, Pouya Tabatabaei Irani, MD, Mohammad Poursalehian, MD, Mahsa Mahanrad, MD, Peyman Mirghaderi, MD, Mohammadreza Razzaghof, MD, Sadegh Saberi, MD

“…The clinical outcomes showed significant improvements in HHS, WOMAC Index, and VAS pain scores. Radiographic analysis revealed acceptable rates of complications, with minimal stem subsidence, no severe bone loss, and a low incidence of radiolucent lines and cortical hypertrophy. …”
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Diagnostics and treatment of pancreatic exocrine insufficiency: clinical guidelines of the Russian gastroenterological association by V. T. Ivashkin, I. V. Mayev, A. V. Okhlobystin, S. A. Alekseyenko, Ye. V. Beloborodova, Yu. A. Kucheryavy, T. L. Lapina, A. S. Trukhmanov, I. B. Khlynov, M. V. Chikunova, A. A. Sheptulin, O. S. Shifrin

“…Patients should be motivated to stop both alcohol intake and smoking as they can cause progression of PEI alone and/or persistence of symptoms, like pancreatic pain.…”
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Clinical characteristics and risk factors of Clostridioides difficile infection in children with diarrhoea by Ning Wang, Kun Jiang, Jinyue Huang, Mengzhu Hou, Lu Wang, Wei Wang, Yulian Fang

“…ObjectiveTo investigate the clinical characteristics and risk factors of Clostridioides difficile infection (CDI) in children with diarrhea, and to provide evidence for the clinical prevention and treatment of CDI.MethodsThe clinical data of 192 children with diarrhoea suspected of CDI admitted from August 2020 to March 2023 were retrospectively analysed and divided into two groups according to whether CDI occurred, and the clinical characteristics and risk factors of the two groups were analysed statistically.ResultsThere were 85 cases of CDI in children with diarrhoea, 60 males (70.6%) and 25 females (29.4%), with a male to female ratio of 2.4:1; clinical manifestations were mostly fever, diarrhoea, abdominal pain, vomiting and blood in stool, with no statistically significant differences compared to the non-infected group. …”
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Prevalence and correlates of symptoms of depression, anxiety, and psychological distress among women of reproductive age with delayed conception in urban and peri-urban low to mid-... by Barsha Gadapani Pathak, Gitau Mburu, Ndema Habib, Rita Kabra, Aiysha Malik, James Kiarie, Ranadip Chowdhury, Neeta Dhabhai, Sarmila Mazumder

“…Factors associated with psychological distress were: (i) a higher total number of children that women intended to have in their lifetime, (ii) longer duration of trying to get pregnant (> 18 months), (iii) continuous effort trying to achieve pregnancy, (iv) women's perception that conception is taking long, (v) social isolation, (vi) being emotionally or verbally abused by husband and family members, and (vii) having other co-morbidities such as hypertension, irregular menstrual cycles, irregular bleeding between regular cycles, abnormal vaginal discharge or pain during sex.<h4>Conclusion</h4>This study demonstrates the high mental health burden faced by women with delayed conception in low- to mid-socioeconomic neighbourhoods of North India including high levels of anxiety and depression. …”
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