Dissemination of Evidence-Based Recommendations for Sickle Cell Disease to Primary Care and Emergency Department Providers in North Carolina: A Cost Benefit Analysis by Paula Tanabe, Audrey L. Blewer, Emily Bonnabeau, Hayden B. Bosworth, Denise H. Clayton, Nancy Crego, Marian F. Earls, Kern Eason, Grayson Forlines, Gary Rains, Matthew Young, Nirmish Shah

“…Individuals with SCD are at high likelihood of high acute care utilization and chronic pain episodes. The multiple complications seen in SCD contribute to significant morbidity and premature mortality, as well as substantial costs to the healthcare system. …”
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Differences in fatty infiltration in thigh muscles and physical function between people with and without knee osteoarthritis and similar body mass index: a cross-sectional study by Jessica B. Aily, Marcos de Noronha, Ricardo J. Ferrari, Stela M. Mattiello

“…Methods Participants aged ≥ 40 years with symptomatic and radiological knee OA group (grade 2 and 3 on the Kellgren and Lawrence (KL) scale) were included in the affected group, while those with no knee pain and no radiological knee OA changes were included in the unaffected group. …”
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Unveiling the hidden burden: Exploring the psychosocial impact of cutaneous leishmaniasis lesions and scars in southern Ethiopia. by Behailu Merdekios, Misgun Shewangizaw, Abebayehu Sappo, Eshetu Ewunetu, Johan van Griensven, Jean-Pierre van Geertruyden, Melissa Ceuterick, Hilde Bastiaens

“…Application of traditional herbal medicine for CL lesions often leads to pus formation and a foul odour, triggering negative attitudes from others, resulting in embarrassment, pain, and anxiety, leading to discomfort and isolation. …”
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Intramedullary Nailing of Proximal Tibia Fractures in Semi-extended Position Using Suprapatellar Approach: Results and Outcomes by Kumar Rohit, Vikas Verma

“…There is also absence of anterior knee pain which is very common in the standard infrapatellar approach due to which its use could be extended for nailing of all types of tibia fractures.…”
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Exploring Force Production Reliability across Different Levels of Clinical Experience during a Simulated One-handed Instrument-Assisted Soft Tissue Mobilization Treatment: A Pilot... by Moni Syeda, Jason Bartholomew, Shayane Valenzuela Santiago, Ashley J Reeves, Nickolai JP Martonick, Scott W Cheatham, Russell T Baker Jr.

“…# Background Instrument-assisted soft tissue mobilization (IASTM) is a commonly utilized intervention for musculoskeletal pain and dysfunction. However, little is known regarding the reliability of forces applied by clinicians of different experience levels during an IASTM intervention…”
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Determination of Probiotics Prescription Indications in Patients with Irritable Bowel Syndrome (Materials of the Expert Council and Literature Review) by V. T. Ivashkin, I. V. Maev, O. P. Alekseeva, S. A. Alekseenko, N. V. Korochanskaya, E. A. Poluektova, V. I. Simanenkov, A. S. Trukhmanov, I. B. Khlynov, V. V. Tsukanov, O. S. Shifrin, T. L. Lapina, R. V. Maslennikov, A. I. Ulyanin

“…Prescription of certain probiotics in IBS is advisable to normalize the frequency and consistency of stools, relieve abdominal pain and bloating, as well as improve patients’ quality of life.…”
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Reasons why osteoarthritis predicts mortality: path analysis within a Cox proportional hazards model by George Peat, Martin J Thomas, Milica Blagojevic-Bucknall, Ross Wilkie, Simran Singh Parmar, Diane Smith, Bethany Jane Seale, Gemma Mansell

“…OA was defined by primary care consultation and moderate-to-severe pain interference in daily life. A Cox proportional hazards analysis determined the total effect (TE) of OA on mortality after adjustment for potential confounders. …”
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Optimizing Healthcare Expenditure for Spinal Cord Stimulation in Italy: The Value of Battery Longevity Improvement and a Direct-to-Implant Approach by Federica Tito, Gianfranco Sindaco, Simon Eggington, Elisa Tacconi, Francesca Borghetti, Mara Corbo, Gilberto Pari

“…**Background:** Spinal cord stimulation (SCS) is a treatment for chronic intractable pain powered by an implantable pulse generator that may be rechargeable or not rechargeable (NR). …”
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Comparison of Glenohumeral Range of Motion Deficits in Youth, Collegiate, and Professional Baseball Players by C. Luke Wilcox, Hillary A. Plummer, Roger V. Ostrander III

“…Individuals with current pain in the arm, shoulder, elbow or shoulder surgery within the prior two years were excluded. …”
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Functional Outcome (Short Term) of Modular Cementless Bipolar HemiArthroplasty (Hydroxyapatite-Coated Stem) for Fracture Neck of Femur in the Elderly by Navin K. Shukla, Lata Keshkar, Jayanta Mukherjee, Ratnesh Kumar, Shivendra Singh, Alok C. Agrawal

“…Twenty-seven patients (62%) were absolutely pain-free. There were no dislocations, revisions, or additional surgeries in any patients. …”
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Exoscope-assisted spine surgery: Current applications and future directions–A short review by Tomas Ferreira, Sakshi Roy, Joecelyn Kirani Tan, Wireko Andrew Awuah, Vallabh Shet, Favour Tope Adebusoye, Adrenito Nicolas, Toufik Abdul-Rahman

“…Spine surgery is a critical field that seeks to alleviate pain and restore function in patients with various spinal pathologies. …”
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Osteoarthritis of the knee joint and its association with metabolic syndrome: A case control study by Rohini Motwani, Arvind Kumar Bodla, Shravan Kumar Peddamadyam, Mrudula Chandrupatla, Nagesh Cherukuri, Maheshwar Lakkireddy, Gunvanti Rathod, Sai Ram Challa, Chowdavarapu Raghavendra Rao, Abhishek Arora, Srikanth Eppakayala, Arcot Reddy Vamsi Krishna

“…Background: Osteoarthritis of the knee joint (OAK) represents a leading cause of pain, functional limitation, and diminished quality of life, particularly among older adults. …”
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Interaction of the gastroenterologist and psychiatrist at management of patient with functional disorder of gastro-intestinal tract by V. T. Ivashkin, Ye. A. Poluektova, A. G. Beniashvili

“…Taking into account patient’s complaints (bloating and abdominal pain relieved after defecation, frequent stool up to 3–5 times per day, incidental imperative urgency to defecation and feeling of incomplete defecation), and long-term benign course of disease, absence of organic changes, according to results of laboratory tests and instrumental investigations irritable bowel syndrome has been diagnosed. …”
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Efficacy of Trimebutine Maleate (Trimedat®) in the Treatment of Patients with Functional Dyspepsia: Results of the “TREND” Observational Study by S. S. Kardasheva, I. M. Kartavenko, N. B. Maksimova, E. Yu. Yurieva, I. R. Popova, Ch. S. Pavlov, V. T. Ivashkin

“…In the group under study, 45 (45 %), 3 (3 %) and 52 (52 %) patients suffered from epigastric pain syndrome (EPS), postprandial distress syndrome (PPDS) and a combination of both syndromes, respectively. …”
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Risk factors for difficult peripheral venous cannulation in hospitalised patients. Protocol for a multicentre case–control study in 48 units of eight public hospitals in Spain by Jose Miguel Morales-Asencio, Ian Blanco-Mavillard, Miguel Angel Rodríguez-Calero, Ismael Fernandez-Fernandez, Luis Javier Molero-Ballester, Catalina Matamalas-Massanet, Luis Moreno-Mejias, Joan Ernest de Pedro-Gomez

“…Introduction Patients with difficult venous access experience undesirable effects during healthcare, such as delayed diagnosis and initiation of treatment, stress and pain related to the technique and reduced satisfaction. …”
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Analytical Approach to the Selection of Research Topics for Gallstone Disease and Acute Cholecystitis (an Overview of Cochrane Reviews) by S. I. Panin, T. V. Nechay, A. V. Sazhin, A. V. Puzikova

“…On the contrary, the achieved values from the estimated DARIS in establishing the differences in the duration between minimally invasive surgery options (21.2 to 76 %), in some issues of pain management in the immediate postoperative period (43.6 to 92.6 %) and additional intraoperative anesthesia (13.7 to 14.9 %) and Z-curve monitoring give hope for their achievement in the foreseeable future. …”
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Phytochemical profile, therapeutic potentials, nutritional composition, and food applications of ginger: a comprehensive review by Great Iruoghene Edo, Ufuoma Augustina Igbuku, Raghda S. Makia, Endurance Fegor Isoje, Tayser Sumer Gaaz, Emad Yousif, Agatha Ngukuran Jikah, Khalid Zainulabdeen, Patrick Othuke Akpoghelie, Rapheal Ajiri Opiti, Arthur Efeoghene Athan Essaghah, Dina S. Ahmed, Huzaifa Umar

“…Ginger exerts its bioactivities via a number of mechanisms such as inhibiting the activation of tumor necrosis factor α and cyclooxygenase-2 in human synoviocytes and limiting the body’s leukotrienes and prostaglandins to elicit anti-inflammatory activity, activating the descendent inhibitory pathways of pain and suppressing the transmission of nociceptive signals thus exhibiting anti-nociceptive effects amongst others. …”
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Osteoperiosteal versus osteochondral for autologous transplantation in the treatment of large cystic osteochondral lesions of the talus by Lequan Liu, Jiangtao Jin, Jinping Pan, Huikang Guo, Sen Li, Jisheng Li, Zheng Zhang

“…Results The within-group comparison showed significant improvements in pain severity and function in both groups post-treatment compared with pre-treatment. …”
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Combination of Gilbert's syndrome and gastrointestinal diseases by G. M. Dubrovina, O. K. Botvinyev, A. I. Kolotilina

“…Patients demonstrate various complaints related to disorders — nausea, decrease of appetite, heartburn, epigastric pain, defecation disorders. Gilbert's syndrome quite often is combined to of the upper gastro-intestinal diseases (gastroduodenitis, esophagitis, sphincter disorders). …”
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Liver cystic echinococcosis: A retrospective study on the demographics and clinical profile of patients managed at a single tertiary institution in central Eastern Cape Province, S... by A Govindasamy, P R Bhattarai, J van Niekerk, J John

“…The mean age of the patients was 37.5 years. Abdominal pain (n=39; 69.6%) was the most common presenting symptom, and a palpable abdominal mass (n=36; 64.3%) was the predominant presenting sign. …”
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