Early removal of indwelling urinary catheters in children undergoing abdominal tumor resection with epidural analgesia by Shachi Srivatsa, Jennifer H. Aldrink, Dana Schwartz, Grant Heydinger, Andrew Davidoff, Andrew J. Murphy, Kyle O. Rove, Sara A. Mansfield

“…Purpose: Epidural analgesia (EA) is commonly employed for postoperative pain management in children undergoing abdominal tumor resection. …”
Get full text

Using Health Utility Index (HUI) for Measuring the Impact on Health-Related Quality of Life (HRQL) Among Individuals with Chronic Diseases by Frank Mo, Bernard C.K. Choi, Felix C.K. Li, Joav Merrick

“…Using the HUI (constructed based on eight attributes: vision, hearing, speech, mobility, dexterity, cognition, emotion, and pain/discomfort) to measure the HRQL for chronic disease patients and to detect possible associations between HUI system and various chronic conditions, this study provides information to improve the management of chronic diseases.This study is of interest to data analysts, policy makers, and public health practitioners involved in descriptive clinical studies, clinical trials, program evaluation, population health planning, and assessments. …”
Get full text

First detection and molecular characterization of porcine epidemic diarrhea virus (PEDV) in India: evidence of a new variant in Karnataka by Jagadish B. Hiremath, M. Swathi, R. Ramamoorthy, M. Shijili, Damini Sharma, Divakar Hemadri, H. B. Chethankumar, K. P. Suresh, Sharanagouda S. Patil, Shivasharanappa Nayakvadi, S. P. Satheesha, B. R. Shome, Baldev Raj Gulati

“…Results This study identified the first clinical outbreak of PEDV in India, with morbidity rates of 55-57.1% and symptoms including yellow watery diarrhea, vomiting, and abdominal pain. PEDV was confirmed in 17 of 21 fecal samples by amplifying the N, S, and M genes. …”
Get full text

Machine learning for predicting severe dengue in Puerto Rico by Zachary J. Madewell, Dania M. Rodriguez, Maile B. Thayer, Vanessa Rivera-Amill, Gabriela Paz-Bailey, Laura E. Adams, Joshua M. Wong

“…Individual warning signs like abdominal pain and restlessness had sensitivities of 79.0% and 64.6%, but lower specificities of 48.4% and 59.1%, respectively. …”
Get full text

Biotechnological Phytocomplex of <i>Zanthoxylum piperitum</i> (L.) DC. Enhances Collagen Biosynthesis In Vitro and Improves Skin Elasticity In Vivo by Giovanna Rigillo, Giovanna Pressi, Oriana Bertaiola, Chiara Guarnerio, Matilde Merlin, Roberto Zambonin, Stefano Pandolfo, Angela Golosio, Francesca Masin, Fabio Tascedda, Marco Biagi, Giulia Baini

“…Biologically, <i>Z. piperitum</i> has antimicrobial, antioxidant, and anti-inflammatory properties, and it is studied for its potential benefits in pain relief and digestive health. This study proposed a novel biotechnological <i>Z. piperitum</i> phytocomplex (ZPP) obtained by plant cell culture for skin health, specifically targeting collagen synthesis, extracellular matrix stability, and resilience against cellular stress. …”
Get full text

Safety evaluation of medroxyprogesterone acetate: a pharmacovigilance analysis using FDA adverse event reporting system data by Luyang Su, Ren Xu, Yanan Ren, Shixia Zhao, Weilan Liu, Zeqing Du

“…Unforeseen significant AEs such as unintended pregnancy (n = 623; ROR, 6.65; ROR025, 6.1; χ2, 2,482.38; PRR, 6.41; EBGM, 5.69; EBGM05, 5.29), bone pain (n = 35; ROR, 13.78; ROR025, 9.4; χ2, 311.2; PRR, 13.75; EBGM, 10.59; EBGM05, 7.69), gait disturbance (n = 34; ROR, 2.82; ROR025, 1.99; χ2, 37.31; PRR, 2.88; EBGM, 2.7; EBGM05, 2.02), dental caries (n = 15; ROR, 23.16; ROR025, 12.32; χ2, 204.26; PRR, 23.14; EBGM, 15.23; EBGM05, 8.98), decrease in blood pressure (n = 15; ROR, 3.88; ROR025, 2.29; χ2, 29.35; PRR, 3.88; EBGM, 3.63; EBGM05, 2.33), and osteonecrosis (n = 9; ROR, 23.44; ROR025, 10.36; χ2, 123.67; PRR, 23.43; EBGM, 15.35; EBGM05, 7.75) were identified as AEs that were not previously outlined in the prescribing information of the medication.ConclusionOur findings align with clinical observations, highlighting the emergence of previously unreported AE signals associated with MPA and their demographic and TTO characteristics. …”
Get full text

Artificial intelligence-enabled non-invasive ubiquitous anemia screening: The HEMO-AI pilot study on pediatric population by Daniel Gordon, Jason Hoffman, Keren Gamrasni, Yotam Barlev, Alex Levine, Tamar Landau, Ronen Shpiegel, Avishai Lahad, Ariel Koren, Carina Levin, Osnat Naor, Hannah Lee, Xin Liu, Shwetak Patel, Gilad Chayen, Michael Brandwein

“…Conclusions This study lays the groundwork for the future evolution of non-invasive, pain-free, and accessible anemia screening tools tailored specifically for pediatric patients. …”
Get full text

Nursing of a patient with ischemic stroke combined with constipation of Qi-deficiency type and melanosis coli treated by acupoint massage (经穴推拿治疗1例缺血性中风合并气虚便秘及结肠黑变病患者的护理体会)... by WANG Xuesong (王雪送), HU Shirong (胡世荣), FAN Yan (范艳), YANG Yu (杨宇), LI Chenchen (李陈晨), LIU Yanna (刘燕娜), LI Mengru (李梦儒), ZHANG Shiyu (张诗语)

“…Based on the comprehensive nursing risk assessment, the two-stage acupoint massage was carried out to relieve the pain and tonify QI-deficiency of the patient. Comprehensive nursing interventions on daily living behavior, dietary and mental health were applied to improve the recovery of gastrointestinal peristalsis and relive the constipation of Qi-deficiency type. …”
Get full text

Chemical Characterization and Differential Lipid-Modulating Effects of Selected Plant Extracts from Côa Valley (Portugal) in a Cell Model for Liver Steatosis by Ricardo Amorim, Mário Pedro Marques, Catarina Melim, Carla Varela, Vilma A. Sardão, José Teixeira, Maria Inês Dias, Lillian Barros, Paulo J. Oliveira, Célia Cabral

“…., and <i>Geranium lucidum</i> L. (pain relief, gastric issues). Given their rich ethnomedicinal history, we evaluated their protective effects on an in vitro model of metabolic dysfunction-associated steatotic liver disease (MASLD). …”
Get full text

Pediatric Patient and Parental Anxiety and Impressions Related to Initial Gastrointestinal Endoscopy: A Japanese Multicenter Questionnaire Study by Shin-ichiro Hagiwara, Yoshiko Nakayama, Manabu Tagawa, Katsuhiro Arai, Takashi Ishige, Takatsugu Murakoshi, Hiroko Sekine, Daiki Abukawa, Hiroyuki Yamada, Mikihiro Inoue, Takeshi Saito, Takahiro Kudo, Yoshitaka Seki

“…In the preendoscopy questionnaire, the most common concerns of the patients and parents before undergoing the procedure were “Pain” (45% of the patients underwent EGD or BE via the oral approach, and 52% of the patients underwent CS or BE via the anal approach) and “Procedural accidents related to the endoscopy” (63% of parents). …”
Get full text

Cardiac manifestations of Fabry disease in G3Stg/GlaKO and GlaKO mouse models-Translation to Fabry disease patients. by Abirami Kugadas, Pietro Artoni, Wanida Ruangsiriluk, Meng Zhao, Natalia Boukharov, Rizwana Islam, Dmitri Volfson, Katayoun Derakhchan

“…FD manifestations include early onset neuropathic pain, gastrointestinal symptoms, and later onset life-threatening renal, cardiovascular and cerebrovascular disorders. …”
Get full text

Intraoperative visualisation and treatment of salivary glands in Sjögren’s syndrome by contrast-enhanced ultrasound sialendoscopy (CEUSS): protocol for a phase I single-centre, sin... by Arjan Vissink, K Hakki Karagozoglu, Tim Forouzanfar, Henk S Brand, Derk Hendrik Jan Jager, Marco Helder, Joseph Bot, Otto Kamp, Seunghee Cha, Gary Weisman, Imke Bartelink

“…Secondary outcomes will consist of determinations of unstimulated whole mouth saliva flow, stimulated whole mouth saliva flow, stimulated parotid saliva flow, clinical oral dryness, reported pain, xerostomia, disease activity, salivary cytokine profiles and clinical SS symptoms. …”
Get full text

The importance of specific exercise therapy in pediatric oncology by Bianca Celine Schmidli, Céline Hammadou, Christina Schindera, Nicolas von der Weid, Uta Tacke, Oliver Faude, Sarah Koch, Fiona Streckmann

“…More and more studies are showing that children have persisting motor and sensory dysfunctions, such as loss of sensation, numbness, pain, absent reflexes as well as loss of balance control. …”
Get full text

Patient satisfaction with radio-frequency identification (RFID) tag localization compared with wire localization for nonpalpable breast lesions: the RFID trial by Raphaël Pete, Céleste Pinard, Fanny Sirodot, Ioana Molnar, Margot Dressaire, Angeline Ginzac, Catherine Abrial, Xavier Durando, Marielle Tekath

“…On a 10-point Visual Analogue Scale, the patients’ median satisfaction score was 9.8 (IQR = 1.32) for the wire group and 10 (IQR = 0.07) for the RFID group (p < 0.001). A reduction in pain between device insertion and surgery was observed in the RFID group (p = 0.009). …”
Get full text

Çocuklarda Dental Anksiyete: Başarılı Dental Tedavinin Önündeki Engel by Aysun Avşar, Büşra Mutlu

“…In children with dental anxiety, increased heart rate, changes in breathing, sweating, abdominal pain, tremor, nausea, dry mouth, crying, restlessness, and distraction are frequently observed during dental treatment. …”
Get full text

HKA angle exceeding 5 degrees is strongly associated with lateral patellar translation beyond 2 mm: surgical recommendations for avoiding adverse effects on the patellofemoral join... by Zheng Jiang, Nan Zhen, Yanjie Mao, Axiang He, Han Guo, Weiming Lin, Diwen Tang, Yang Qu, Tsung-Yuan Tsai, Wanjun Liu

“…Abstract Purpose Previous studies reported that anterior knee pain (AKP) occurs with an incidence of 32% after opening-wedge high tibial osteotomy (OWHTO). …”
Get full text

Clinicopathological analysis of adrenal intravascular large B-cell lymphoma by LIN Jiaxin, WEI Ran, SHUI Ruohong, LU Hongfen, LI Xiaoqiu, YU Baohua

“…Two cases had low-grade fever, 1 case had abdominal pain, 1 case was found by physical examination, and the information of the remaining one was unknown. …”
Get full text

Association of epidural labor analgesia with maternal and neonatal outcomes in women with preeclampsia: a propensity score-matched single-center retrospective cohort study by Xi-Zhu Wu, Tuan-Fang Fang, Yi-Han Zheng, Su-Jing Zhang, Yi Xie, Xiang Gao, Guo-Lin Lu

“…Abstract Background Epidural labor analgesia (ELA) is widely and safely used for labor pain relief. However, it remains unclear whether ELA affects maternal and neonatal outcomes in women suffering from preeclampsia. …”
Get full text

Effect of Esketamine on Cognitive Recovery After Propofol Sedation for Outpatient Colonoscopy: A Randomized Clinical Trial by Liu D, Gao X, Zhuo Y, Cheng W, Yang Y, Wu X, Yang H, Yao Y

“…The esketamine group demonstrated higher satisfaction (P = 0.003) and significantly reduced incidences of hypotension (14.3% vs 36.5%, P < 0.001), bradycardia (5.6% vs 15.1%, P = 0.013), hypoxemia (2.4% vs 8.7%, P = 0.028), and injection site pain (21.4% vs 48.4%, P < 0.001).Conclusion: Adding esketamine 0.2 mg/kg to propofol for colonoscopy sedation improved postoperative cognitive recovery, enhanced patient satisfaction, and reduced cardiopulmonary adverse events without prolonging discharge time. …”
Get full text

Clinical outcomes following surgical fixation of acromion fractures by Tram L. Tran, MD, MPH, Molly G. Sekar, MD, Nik Bhardwaja, BS, Jessica McGraw-Heinrich, MD, Michael D. McKee, MD, Niloofar Dehghan, MD

“…Surgical fixation of acromion fractures can improve the shoulder range of motion and pain scores. The nonunion rate is lower for surgical fixation compared to existing literature on nonoperative treatment of acromion fractures.…”
Get full text