Clinical Observation on Children with Peripheral Facial Paralysis Treated by Acupoint Injection of Mouse Nerve Growth Factor Combined with Acupuncture by Mian KONG, Wei LIU, Zhihua YU, Ming FANG

“…No serious adverse reactions occurred in this study. One case with local pain occurred in the observationgroup but without statistical difference (<italic>P</italic>&gt; 0.05).Conclusion:The total effective rate of acupoint injection of mouse nerve growth factor combined with acupuncture in the treatment of children with peripheral facial paralysis is higher than that of acupuncture only, and the effective time is significantly shorter than that of acupuncture only. …”
Get full text

A Study of Combined Onabotulinumtoxin A and Hyaluronic Acid Filler for the Treatment of Enlarged Facial Pores by Vasanop Vachiramon, Sonphet Chirasuthat, Suphagan Boonpethkaew, Nawara Sakpuwadol, Tanat Yongpisarn, Natthachat Jurairattanaporn

“…The outcomes were measured by pore volume, visual assessment, pain score, improvement score, and side effects at various time intervals up to 24 weeks. …”
Get full text

Effects of the Highly COX-2-Selective Analgesic NSAID Etoricoxib on Human Periodontal Ligament Fibroblasts during Compressive Orthodontic Mechanical Strain by Christian Kirschneck, Erika Calvano Küchler, Michael Wolf, Gerrit Spanier, Peter Proff, Agnes Schröder

“…The highly COX-2-selective NSAID etoricoxib has a favorable systemic side effect profile and high analgesic efficacy, particularly for orthodontic pain. In this in vitro study, we investigated possible side effects of two clinically relevant etoricoxib concentrations on the expression pattern of mechanically strained hPDL fibroblasts and associated osteoclastogenesis in a model of simulated orthodontic compressive strain occurring during orthodontic tooth movement. hPDL fibroblasts were incubated for 72 h under physiological conditions with etoricoxib at 0 μM, 3.29 μM, and 5.49 μM, corresponding to clinically normal and subtoxic dosages, with and without mechanical strain by compression (2 g/cm2) for the final 48 h, simulating conditions during orthodontic tooth movement in compressive areas of the periodontal ligament. …”
Get full text

Оцінювання ефективності фізичних вправ для ліквідації діастазу прямих м’язів живота в жінок у постпартумі... by N.M. Kinash, I.V. Levytskyi, I.V. Kravchuk, D.S. Martyniuk

“…Системні скарги, пов’язані з ДПМЖ, оцінено за спеціалізованим опитувальником VHPQ (Ventral Hernia Pain Questionnaire), який дав змогу визначити якість повсякденної діяльності. …”
Get full text

A ROS-responsive hydrogel encapsulated with matrix metalloproteinase-13 siRNA nanocarriers to attenuate osteoarthritis progression by Qiuyang Wang, Kai Feng, Guangsheng Wan, Wei Liao, Jing Jin, Peng Wang, Xiaolian Sun, Weijun Wang, Qing Jiang

“…The si-Fe-HPP treatment not only notably alleviated synovitis, osteophyte formation and subchondral bone sclerosis, but also markedly improved physical activity and reduced pain in DMM-induced OA mice. This study reveals that si-Fe-HPP, with its ROS-responsive and RNAi abilities, can significantly protect chondrocytes and attenuate OA progression, providing novel insights and directions for the development of therapeutic materials for OA treatment. …”
Get full text

USC-Derived Small Extracellular Vesicles-Functionalized Scaffolds Promote Scarless Vaginal Defect Repair via Delivery of Decorin and DUSP3 Proteins by Xu Y, Li J, Qiu Y, Wu F, Xue Z, Liu B, Fan H, Zhou Y, Wu Q

“…Compared to skin scars, vaginal scars can lead to pain during intercourse and urinary difficulties, severely impacting quality of life. …”
Get full text

Biomineralized PEEK cages containing osteoinductive CaP bioceramics promote spinal fusion in goats by Qiujiang Li, Bowen Hu, Linan Wang, Lei Wang, Cong Feng, Zhuang Zhang, Zhipeng Deng, Yang Xiao, Bo Yuan, Xiangdong Zhu, Xiangfeng Li, Xi Yang, Yueming Song, Xingdong Zhang

“…Interbody fusion devices are critical in spinal surgery to restore spinal stability, reduce pain and improve function. Polyetheretherketone (PEEK) has become a commonly used alternative material for fusion cages owing to its excellent mechanical properties and biocompatibility, but its biological inertness limits bone regeneration and may lead to poor fusion. …”
Get full text

Phenylalanine-derived β-lactam TRPM8 antagonists: revisiting configuration and new benzoyl derivatives by Cristina Martín-Escura, Maria Angeles Bonache, Alicia Medina-Peris, Thomas Voets, Antonio Ferrer-Montiel, Asia Fernández-Carvajal, Rosario González-Muñiz

“…N-terminal benzoyl derivatives, which increased TPSA values, resulted in equipotent compounds as previous prototypes, but also showed activity in other pain-related targets [TRPV1 and cannabinoid receptor, subtype 2 (CB2R)]. …”
Get full text

Pediatric reference values for total psoas muscle area in Korean children and adolescents by Jisoo Kim, Mi-Jung Lee, Hyun Ji Lim, Yonghan Kwon, Kyunghwa Han, Haesung Yoon

“…BackgroundUniform cut-off values cannot be applied to children because muscle mass changes significantly with growth and different population groups have different races and lifestyles, so reference values from healthy children are needed.Materials and methodsPediatric patients (≤18 years of age) who underwent abdominal CT for abdominal pain in the emergency room without a past history from January 2015 to January 2021 were enrolled. …”
Get full text

Holographic meridian scraping on patient with essential hypertension of phlegm-blood stasis type: A case report of treatment and nursing experience (全息经络刮痧疗法干预痰瘀互结型原发性高血压1例效果观察及护理体... by ZHANG Man (张曼), DONG Chunfang (董春芳), ZHANG Ruoyin (张若荫), XUE Li (薛丽), Deng Yulong (邓玉龙)

“…The results showed that the symptoms of dizziness, headache and insomnia were significantly improved, and the TCM syndrome score decreased and symptoms of cervical pain were relieved to a great extent. It shows that holographic meridian scraping therapy has a significant intervention effect on Phlegm and blood stasis type hypertension. …”
Get full text

Clarithromycin-Associated Acute Liver Failure Leading to Fatal, Massive Upper Gastrointestinal Hemorrhage from Profound Coagulopathy: Case Report and Systematic Literature Review by Ahmed I. Edhi, Seifeldin Hakim, Christienne Shams, Damanpreet Bedi, Mitual Amin, Mitchell S. Cappell

“…A 60-year-old nonalcoholic man, with normal baseline liver function tests, was admitted with diffuse abdominal pain and AST = 499 U/L and ALT = 539 U/L, six days after completing a 7-day course of clarithromycin 500 mg twice daily for suspected upper respiratory infection. …”
Get full text

Bell’s palsy misdiagnosis: characteristics of occult tumors causing facial paralysis by Eun-Jae Chung, Damir Matic, Kevin Fung, S. Danielle MacNeil, Anthony C. Nichols, Ruba Kiwan, KengYeow Tay, John Yoo

“…An irreversible, progressive pattern of facial paralysis combined with pain, multiple cranial neuropathies or history of skin cancer were predictable risk factors for occult tumors. …”
Get full text

CMV Pancreatitis in an Immunocompromised Patient by Jaffer Ahmad, Najia Sayedy, Raghavendra Sanivarapu, Jagadish Akella, Javed Iqbal

“…A 45-year-old Hispanic female with no past medical history presented to the emergency department (ED) for three days of abdominal pain associated with nausea, vomiting, and diarrhea. …”
Get full text

Evaluation of the Feasibility of Transfusing Leukocyte Depletion Filter–Processed Intraoperative Cell Salvage Blood in Metastatic Spine Tumor Surgery: Protocol for a Non–Randomized... by Naresh Kumar, Si Jian Hui, Renick Lee, Sahil Athia, Joel Yong Hao Tan, Jonathan Jiong Hao Tan

“…Available patient data will be reviewed to determine tumor burden secondary to metastasis and postoperative survival and disease progression, improvement in pain, and neurological and ambulatory status. Data collected will be studied postoperatively at 3, 6, 12, 24, 36, and 48 months or until demise, whichever occurs first. …”
Get full text

Anemia in pregnancy: a systematic review and meta-analysis of prevalence, determinants, and health impacts in Egypt by Ahmed Azzam, Heba Khaled, Alrefaey K. Alrefaey, Amar Basil, Sarah Ibrahim, Mohamed S. Elsayed, Muhammad Khattab, Nashwa Nabil, Esraa Abdalwanees, Hala Waheed Abdel Halim

Get full text

Heart rate cost as a tool for monitoring recovery between acute training sessions by José Morais Souto Filho, Milton Rocha de Moraes, Patrício Lopes de Araújo Leite, Larissa Alves Maciel, Andréa Cândida Arruda Andrade Rezende, Thiago dos Santos Rosa, Fabiana Andrade Machado, Sergio Rodrigues Moreira, Ricardo Yukio Assano, Marcelo Magalhães Sales, Herbert Gustavo Simões

“…Assessments included anamnesis, blood tests (CPK, cortisol, testosterone), body composition analysis, blood pressure, heart rate (HR), heart rate variability (HRV), pain scale, vertical jump (VJ), and a 6-minute submaximal running test to determine HRC (HR/running velocity). …”
Get full text

Effect of exercise intervention on health-related quality of life in middle-aged and older people with osteoporosis: a systematic review and meta-analysis by Di Geng, Xiaogang Li, Yan Shi

“…In terms of physical HRQOL, significant improvements were observed in bodily pain (SMD = 0.51, 95% CI [0.24–0.78], p= 0.0002), physical function (SMD = 0.56, 95% CI [0.21–0.91], p = 0.002), role physical (SMD = 0.39, 95% CI [0.14–0.64], p = 0.003), and general health (SMD = 0.68, 95% CI [0.25–1.11], p = 0.002). …”
Get full text

Transauricular vagus nerve stimulation in preventing post-traumatic stress disorder in emergency trauma surgery patients in China: a study protocol for a multicenter, double-blind,... by Jun Zhang, Xin Yu, Gang Chen, Yu Li, Qi-Hong Shen, Xinru Lin, Tieshuai Liu, Yunyun Yu, Jingwen Liang

“…The intensity will start at 0.4 V, increasing in 0.4 V increments until a tingling sensation is detected, and will be adjusted to the highest tolerable level without causing pain. The initial intervention will begin once informed consent is obtained and randomisation is completed in the preoperative preparation room, continuing until the surgery is finished. …”
Get full text

Efficacy and safety of ketamine and esketamine in reducing the incidence of postpartum depression: an updated systematic review and meta-analysis by Moaz Yasser Darwish, Abdallah A. Helal, Yousif Ahmed Othman, Manar Alaa Mabrouk, Aya Alrawi, Taha Abd-ElSalam Ashraf, Nada K. Abdelsattar, Fatma Mohammed Sayed, Mohamed Abd-ElGawad

“…We extracted PPD occurrence rate, PPD score, pain score and side effects. Finally, a meta-analysis was conducted using RevMan software. …”
Get full text

Physical activity in patients after bariatric surgery - a literature review by Martyna Śliwińska, Anna Podraza, Małgorzata Wirkijowska, Jakub Wirkijowski, Katarzyna Wójtowicz, Agata Walczak, Wiktoria Gajek-Flanczewska, Sebastian Flanczewski, Paulina Woźniak, Ewa Wietrzykowska, Dominika Sobolewska, Katarzyna Michalczyk-Fraszka

“…It also explores the unique challenges associated with primary obesity and post-bariatric surgery, such as joint pain, loose skin, nutritional deficiencies, and psychological barriers, which often prevent patients from engaging in PA.   …”
Get full text