Clinically SUspected ScaPhoid fracturE: treatment with supportive bandage or CasT? ‘Study protocol of a multicenter randomized controlled trial’ (SUSPECT study) by Max Reijman, Jan A N Verhaar, Abigael Cohen, Gerald A Kraan, Nina M C Mathijssen, Marc A Koopmanschap, Sander Mol, Joost W Colaris

“…Secondary outcomes include functional outcome, recovery of function, pain, patient satisfaction, quality of life and cost-effectiveness measured by medical consumption, absence from work or decreased productivity.Ethics and dissemination The Medical Ethics Committee of the Erasmus MC Medical Centre, Rotterdam, approved the study protocol (MEC-2017-504). …”
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Incorporating low haemoglobin into a risk prediction model for conversion in minimally invasive gynaecologic oncology surgeries by Kevin H. Nguyen, Hyundeok Joo, Solmaz Manuel, Lee-may Chen, Lee-lynn Chen

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The Effect of Blood Flow Restriction Therapy on Shoulder Function Following Shoulder Stabilization Surgery: A Case Series by John H. McGinniss, John S. Mason, Jamie B. Morris, Will Pitt, Erin M. Miller, Michael S. Crowell

“…Statistically significant and clinically meaningful improvements were reported on the Single Assessment Numeric Evaluation (*p* \< 0.001; mean difference, 17.7; CI: 9.4, 25.9) and Shoulder Pain and Disability Index (*p* \< 0.001; mean difference, -31.1; CI: -44.2, -18.0) from six to 12 weeks postoperatively. …”
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Effects of dexmedetomidine combined with intravenous general anesthesia on hemodynamics and inflammatory factors in patients undergoing laparoscopic colorectal cancer surgery by Chunling Liu, Yong Gui, Min Zeng, Zhidong Zhou

“…Dexmedetomidine is a local anesthetic that reduces pain and discomfort during surgery. Aim: The aim of this study was to investigate the efficacy of application of dexmedetomidine combined with total intravenous anesthesia in laparoscopic CRC surgery, with particular focus on its effects on patient hemodynamics and inflammatory factors. …”
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Short-Term Observation of Ultrasonic Cyclocoagulation in Chinese Patients with End-Stage Refractory Glaucoma: A Retrospective Study by Dongpeng Hu, Shu Tu, Chengguo Zuo, Jian Ge

“…Scleral thinning existed in 12 eyes, among which 2 developed hypotony (2 mmHg and 3 mmHg). Average pain score decreased massively compared with baseline data. …”
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A real-world Pharmacovigilance study of brodalumab based on the FDA adverse event reporting system by Ke He, Kaidi Zhao, Tingyi Yin, Meng Liu, Jiashu Liu, Wenqian Du, Xinyi Liu, Baochen Cheng, Dewu Zhang, Yan Zheng

“…The study identified several adverse reactions already listed on the drug’s label that showed positive signals, including arthralgia, headache, myalgia, suicidal ideation, oropharyngeal pain, injection site mass, and infections. Additionally, we found potential adverse reactions not noted on the drug’s label that exhibited positive signals, including depression, increased blood pressure, peripheral swelling, gait disturbance, inability to walk, stress, myocardial infarction, sepsis, uveitis, nephrolithiasis, and interstitial lung disease. …”
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Independent Heath Facility Meets Cancer Care Ontario and Canadian Association of Gastroenterology Guidelines for Endoscopic Procedure Wait Times While Meeting Quality Indicators: A... by Fraser Kegel, Niv Sne, Timothy Rice, Eric Joy, Shayan Shahsavar, Celeste A. Collins, Maria Gagarine, Alexandra Allard-Coutu, Lisa Klotz, Angela Coates, Kamyar Kahnamoui, Marko Simunovic

“…Median wait times from referral to colonoscopy met the recommendations set out by the Canadian Association of Gastroenterology and Cancer Care Ontario for all indications: chronic abdominal pain: 43 days; new onset change in bowel habits: 36 days; bright red rectal bleeding: 42 days; documented iron-deficiency anemia: 43 days; fecal occult blood test positive: 38 days; cancer likely based on imaging or physical exam: 23 days; chronic diarrhea and chronic constipation: 42 days; and screening colonoscopies: 55 days. …”
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Clinical Features and Dynamics of T Cells-Related Markers in Immunocompetent Patients with Cytomegalovirus Hepatitis by Takuya Komura, Takashi Kagaya, Hideo Takayama, Masahiro Yanagi, Takatoshi Yoshio, Saiho Sugimoto, Michiko Nishino, Noriaki Orita, Yoshiro Asahina, Masashi Nishikawa, Shuichi Kaneko, Masashi Unoura

“…Fever (74.5%), hepatosplenomegaly (74.5%), sore throat (36.2%), headache (31.9%), abdominal pain (27.7%), lymphadenopathy (23.4%), and skin rash (6.4%) were present at admission. …”
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Comparing the Effectiveness of Intra-articular Injection with Autologous Platelet-rich Plasma vs Hyaluronic Acid vs Platelet-derived Growth Factors in Early Osteoarthritis of Knee... by Vidya S Konana, Harish S Yallapura, Sriharsha Bettaswamy, Srinivas P Sivaram, Darshan G Thimmegowda

“…Aims: To compare the effectiveness between intra-articular injection (IAI) of autologous platelet-rich plasma (PRP) vs hyaluronic acid (HA) vs activated PRP in primary osteoarthritis (OA) of the knee grades 1 and 2, in terms of pre- and postinjection functional outcome by the Western Ontario and McMaster Universities Arthritis Index (WOMAC) scale, and pre- and postinjection pain by visual analog scale (VAS). Materials and methods: The patients were divided into three groups based on the treatment they received. …”
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Nursing of a patient with chemotherapy-induced oral ulcer treated with Traditional Chinese Medicine mouthwash combined with moxibustion (中药含漱疗法联合艾灸治疗化疗相关性口腔溃疡1例的护理)... by LI Fang (李芳), LIU Shuhong (刘书红), ZHAO Yanan (赵亚楠), ZHAO Yan (赵燕)

“…The patient's oral ulcer pain decreased and the ulcer surface shrank after treatment. …”
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Posttranslational Nitration of Tyrosine Residues Modulates Glutamate Transmission and Contributes to N-Methyl-D-aspartate-Mediated Thermal Hyperalgesia by Carolina Muscoli, Concetta Dagostino, Sara Ilari, Filomena Lauro, Micaela Gliozzi, Erlisa Bardhi, Ernesto Palma, Vincenzo Mollace, Daniela Salvemini

“…The broader implication of our findings reinforces the notion that free radicals may contribute to various forms of pain events and the importance of the development of new pharmacological tool that can modulate the glutamate transmission without blocking its actions directly.…”
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Pseudoaneurysm of the Anterior Tibial Artery following Ankle Arthroscopy in a Soccer Player by Ichiro Tonogai, Tetsuya Matsuura, Toshiyuki Iwame, Keizo Wada, Tomoya Takasago, Tomohiro Goto, Daisuke Hamada, Yohei Kawatani, Eiki Fujimoto, Tetsuya Kitagawa, Shyoichiro Takao, Seiji Iwamoto, Moriaki Yamanaka, Masafumi Harada, Koichi Sairyo

“…Surgeons should look carefully for postoperative ankle swelling and pain after ankle arthroscopy.…”
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Mirizzi Syndrome: Diagnosis and Management of a Challenging Biliary Disease by Gennaro Clemente, Andrea Tringali, Agostino M. De Rose, Elena Panettieri, Marino Murazio, Gennaro Nuzzo, Felice Giuliante

“…Presenting symptoms were jaundice, pain, and cholangitis. Preoperative diagnosis of Mirizzi syndrome was achieved in 11 patients, while 6 had a diagnosis of gallbladder cancer and 1 of Klatskin tumor. …”
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A Retrospective Evaluation of the Utility of Capsule Endoscopy and Double-Balloon Endoscopy in Crohn’s Disease by Masanao Nakamura, Yoshiki Hirooka, Osamu Watanabe, Takeshi Yamamura, Kohei Funasaka, Eizaburo Ohno, Hiroki Kawashima, Ryoji Miyahara, Hidemi Goto

“…Multivariate analysis indicated small bowel stenosis and abdominal pain as factors significantly associated with useful indications. …”
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Predicting bursal-side supraspinatus tendon tears with the acromioclavicular angle by Nadhaporn Saengpetch, Jaturong Bamrungchaowkasem, Niyata Chitrapazt, Pinkawas Kongmalai

“…Methods: In this retrospective case-control study, patients presenting with shoulder pain between January 2016 and February 2020 were reviewed. …”
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Parathyroid Adenoma - The Leading Cause of Primary Hyperparathyroidism: Case Report by Martyna Zielnik, Julia Dubel, Szymon Kalinowski, Sabina Kadłubek, Patrycja Rembisz, Anna Czuba, Pola Knurowska, Klaudia Serafin, Aleksander Wrona, Aleksandra Słowikowska

“…The predominant etiology of primary hyperparathyroidism is the presence of a parathyroid adenoma. (7) This case report presents a 68-year-old female patient with a history of osteoporosis, diagnosed in 2019 for osteoarticular pain and hypercalcemia. The suboptimal response to standard osteoporosis treatment was an indication to expand the diagnosis of calcium-phosphate disorders accompanying osteoporosis. …”
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Efficacy and Tolerability of Two Different Low-Volume Split-Dose Polyethylene Glycol Electrolytes Solution Bowel Preparation for Morning Colonoscopy by Hefeng Tian, Hui Li, Xuanrui Zhu, Wenlong Liu, Ying Fan, Lei Shi, Xiu Wang

“…For the comparison of the patients’ bowel tolerance, there were no statistical differences between the two groups regarding thirst, abdominal pain or abdominal discomfort, abdominal distension, dizziness or headache, anal discomfort, and sleep disturbance (P>0.05). …”
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Chronic Atrophic Gastritis Presenting as Hemolytic Anemia due to Severe Vitamin B12 Deficiency by Amanda M. Woodford, Rabhea Chaudhry, Gabriella A. Conte, Varsha Gupta, Madhurima Anne

“…This case describes a 46-year-old male with no past medical history who presented with chest pain, fatigue, and progressive weakness, found to have hemolytic anemia, ultimately attributed to vitamin B12 deficiency. …”
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Potential common targets of music therapy intervention in neuropsychiatric disorders: the prefrontal cortex-hippocampus -amygdala circuit (a review) by Yuqin Dan, Ying Xiong, Danghan Xu, Yuqi Wang, Meng Yin, Pengwei Sun, Yi Ding, Ziyun Feng, Peng Sun, Weili Xia, Gongchang Yu, Gongchang Yu, Li Li, Li Li

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Clinical Dental Midline Shift Is Not a Predictor of the Side of Shorter Hemimandible: A Cone Beam Computed Tomography Diagnostic Study by Lígia Pereira da Silva, Alicia López-Solache, Urbano Santana-Penín, José López-Cedrún, María Jesus Mora, Pablo Varela-Centelles, Antonio González-Mosquera, Almudena Rodríguez-Fernández, Urbano Santana Mora

“…Tomographic images were acquired using the i-CAT^® Imaging System; mandibular/maxillary measurements were obtained with the Planmeca Romexis^® software v.6.This is an ancillary study of a clinical trial (NCT02144233) that included chronic pain (TMD diagnosis; DC/TMD criteria), fully dentate, and stable normo-occlusion participants. …”
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