Assessment of a novel unidirectional mid-term absorbable barbed suture versus a competitor barbed suture for vaginal cuff closure after gynaecology surgery, study protocol of a ran... by Petra Baumann, Lourdes Hinojosa Sánchez, Núria Grané Garcia, Larisa Sologiuc, Amadeus Hornemann

“…As secondary objectives, the following parameters will be collected and compared in both suture groups: intraoperative handling of the suture material, quality of life using the Female Sexual Function Index (FSFI), patient satisfaction, pain, and complications occurring in the short-term and long-term follow-up. …”
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Can T1W and T2W Dixon Sequences Replace the Standard MRI Protocol in Diagnosing Sacroiliitis? by Nur Betül Karatoprak, Zeynep Maraş Özdemir, Sinan Karatoprak, Ayşegül Sağır Kahraman, Leyla Karaca, Servet Yolbaş

“…The patients with inflammatory low-back pain (aged 18–50 years) were included. The exclusion criteria included pregnancy, pelvic infection/malignancy history, pelvic metal implants or foreign body artefacts. …”
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Deciphering In Vitro and In Vivo Pharmacological Properties of Seed and Fruit Extracts of Flacourtia jangomas (Lour.) Raeusch by Farhana Alam Ripa, Fowzia Alam, Fahmida Haque Riya, Yesmin Begum, Sharmin Akter Eti, Nusratun Nahar, Zebunnesa Ahmed, Sabrina Sharmin

“…In both in vivo analgesic tests, SFJC demonstrated substantial (p<0.01) pain inhibition percentages (tail immersion: 49.46%; acetic acid writhing: 66.43%) at a dose of 600 mg/kg. …”
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Diagnostic accuracy of drooling, reluctance, oropharynx, others, and leukocytosis score as a predictor of mortality and complications following acute corrosive ingestion by Fawaz Poonthottathil, Soorya Suresh, Jamshed Nayer, Praveen Aggarwal

“…Nausea, vomiting, and pain abdomen were the common symptoms. The median DROOL score was 4. …”
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Aberrant SNHG expression predicts poor prognosis in esophageal cancer using meta-analysis and bioinformatics analysis by Ke Shi, Li-De Huang, Dan Li, Wei-Min Luo, Hua-Song Liu, Dong-Xiao Ding, Qiang Guo, Yue-Feng Liu

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An Unusual Case of Mandibular Squamous Cell Carcinoma in Intimacy with an Impacted Wisdom Tooth by Johnson Cheung, Ayham Al Afif, Martin Joseph Bullock, Chad Robertson, Robert Hart, Reginald Goodday

“…Herein, we report a case of mandibular squamous cell carcinoma in a 53-year-old male who presented with symptoms of right facial swelling, trismus, pain, and right-sided lip paresthesia. The patient underwent a surgical removal of the presumed infected third molar of the right mandible, but histopathological analysis of the associated soft tissue unexpectedly yielded squamous cell carcinoma. …”
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Comprehensive Medical and Psychological Rehabilitation in War Trauma (clinical case) by O.A. Panchenko, A.V. Kabantseva, O.O. Zhogina, I.A. Serdyuk

“…Supination and pronation of the right hand became clearer and less painful (from 8 to 2 points), movement in the fingers of the right hand increased and became more steady, a clear pulsation appeared in the area of the skin defect on the right forearm, regression of pain in the elbow and shoulder joints on the right was noted, and the patient began to walk without a mobilization bandage. …”
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Efficacy of adalimumab in pediatric non-infectious uveitis with and without anterior segment inflammation by Chunbo Zhang, Xiaorong Xue, Jinan Xiao, Qiongge Li, Yuyao Zhai, Ying Chen

“…Adverse events observed during the study period included abdominal pain, skin erythema, articular symptoms and respiratory infections. …”
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Impact of a synchronous prophylactic treatment of the anterior accessory saphenous vein on the recurrent varicose vein rate in patients undergoing thermal ablation of an insufficie... by Lorenz Uhlmann, Christine Fink, Karsten Hartmann, Thomas Mattausch, Hans-Christian Wenzel, Phillip Zollmann, Jürgen Veltman, Thomas Weiler, Guido Lengfellner, Lars Müller, Markus Stücker, Felizitas Pannier, Carmen Dietrich, Tobias Hirsch

“…Primary study endpoint is the recurrence rate; secondary endpoints include inter alia, complication rate, postoperative pain intensity, quality of life and patient satisfaction.Ethics and dissemination Before initiation of the study, the protocol was presented and approved by the independent ethics committee of the medical faculty of the University of Heidelberg (Ethics approval number S-596/2018). …”
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SOCS1 deficiency—crossroads of autoimmunity and autoinflammation—two case reports by Kajetan Trojovsky, Maximilian Seidl, Florian Babor, Stephan Ehl, Stephan Ehl, Min Ae Lee-Kirsch, Michael Friedt, Hans-Juergen Laws, Nibras Naami, Prasad Thomas Oommen, Sujal Ghosh

“…Patient 1, a 16-year-old male from Guinea, presented with Evans Syndrome, musculoskeletal pain and elevated liver enzymes. Patient 2, a 6-year-old German boy, developed recurrent oral aphthous ulcers, mild inflammatory bowel disease and chronic recurrent multifocal osteomyelitis. …”
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Economic impact of prolonged tracheal extubation times on operating room time overall and for subgroups of surgeons: a historical cohort study by Franklin Dexter, Anil A. Marian, Richard H. Epstein

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Emergency Medical Services Provider-Perceived Alzheimer’s Disease and Related Dementias in the Prehospital Setting by Esmeralda Melgoza, Valeria Cardenas, Hiram Beltrán-Sánchez

“…Among cases with EMS provider-perceived ADRD, the most common primary impressions were mental disorders (17.1%), weakness (17.0%), injury (15.7%), and pain (13.1%). Increasing age was associated with higher odds of EMS provider-perceived ADRD among both sexes. …”
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Mesenchymal Stem Cells for Cartilage Regeneration of TMJ Osteoarthritis by Dixin Cui, Hongyu Li, Xin Xu, Ling Ye, Xuedong Zhou, Liwei Zheng, Yachuan Zhou

“…Temporomandibular joint osteoarthritis (TMJ OA) is a degenerative disease, characterized by progressive cartilage degradation, subchondral bone remodeling, synovitis, and chronic pain. Due to the limited self-healing capacity in condylar cartilage, traditional clinical treatments have limited symptom-modifying and structure-modifying effects to restore impaired cartilage as well as other TMJ tissues. …”
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LGBTQ+ status and sex of record in Veterans with post-traumatic stress disorder: demographics, comorbidities, and outpatient encounters by Terri Elizabeth Workman, Terri Elizabeth Workman, Joseph L. Goulet, Joseph L. Goulet, Cynthia A. Brandt, Cynthia A. Brandt, Melissa Skanderson, Melissa Skanderson, John O’Leary, John O’Leary, Kirsha S. Gordon, Kirsha S. Gordon, Qing Treitler-Zeng, Qing Treitler-Zeng

“…There were significant differences found in age, marital status, and medical care usage, as well as pain, mental health, and substance use disorder diagnoses. …”
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Protocol for a first-in-human feasibility study of T regulatory cells (TR004) for inflammatory bowel disease using (ex vivo) Treg expansion (TRIBUTE) by Jennifer Clough, Peter Irving, A Toby Prevost, Graham M Lord, Joana Vasconcelos, James B Canavan, Beverley Rodger, D Macallan

“…Introduction Crohn’s disease (CD) is a chronic, immune-mediated inflammatory bowel disease (IBD), presenting with symptoms of abdominal pain and bleeding from the gastrointestinal tract. …”
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Prevention and treatment of recurrent fractures after percutaneous vertebroplasty with denosumab in patients with osteoporotic vertebral compression fractures by Shouyu Xiang, Cheng Tang, Long Ling, Wei Liu, Bingwen Bai, Yanming Cao

“…[Conclusion] Denosumab treatment effectively relieves pain after percutaneous vertebroplasty in patients with osteoporotic vertebral compression fractures, promotes fracture healing, increases vertebral bone mineral density, and reduces the incidence of vertebral refractures.…”
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A novel approach for managing the incisions of tibial plateau fractures with soft tissue swelling by Yang Zhang, Yangyang Zhao, Shuanggong Liu, Zihan Yao, Zikang Jin, Wanli Ma

“…Preoperative and postoperative complications were assessed in both groups, and pain condition, degree of arthritis, limb function, imaging results, and quality of life were evaluated using validated scales. …”
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Cubital Tunnel Syndrome - Modern Treatment Options by Aleksandra Sieradzka, Krzysztof Szerej, Alicja Kot, Marta Wojtczak, Natalia Myśliwiec, Adrian Różycki, Michał Pniak, Paweł Miklis, Maciej Mawlichanów, Aleksandra Ciesielska

“…Patients typically present with symptoms of paresthesia in the fourth and fifth digits, accompanied by hand weakness and pain. Most patients respond well to conservative treatments, but some of them require surgical intervention. …”
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Impact of Exercise on Tramadol-Conditioned Place Preference by Haneen Amawi, Alaa M. Hammad, Aseel Abdullah Ibrahim, Nosyba Alsbih, Frank Scott Hall, Fawaz Alasmari, Bahaa Al-Trad

“…Background: Tramadol (TRA) is an opioid that is used to manage moderate to severe pain. Long-term use of TRA can lead to the development of opioid use disorder. …”
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Is There a Mild Form of Pediatric Appendicitis? An Eight-Year Single-Center Retrospective Review by Eric Scheier, Khaled Khalilia, Pavel Peslin, Stav Amir, Luba Pasherstnik Bizer

“…While pediatric appendicitis should not be ruled out in the presence of a normal laboratory evaluation, cases that present without gastrointestinal symptoms, without severe pain, and with an appendiceal diameter and inflammatory markers below a certain threshold may warrant continued observation and serial ultrasound to evaluate for progression prior to initiating therapy.…”
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