One-stage versus two-stage video-assisted thoracic surgery for synchronous bilateral pulmonary nodules: protocol for a single center, non-randomized clinical trial (OTVATS-1) by Yu Han, Weixun Zhang, Peihang Xu, Zhoujunyi Tian, Yang Hao, Jin Zhang, Tai Ren, Chaoyang Liang

“…Secondary outcomes include 5-year disease free survival, 3-year overall survival, 3-year disease free survival, overall complications rate, 30-day mortality, pain score after surgery, surgical time, blood loss in the operation, duration of chest tube, length of stay, and quality of life score after surgery. …”
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Daily activity, mood, and quality of life in colorectal cancer patients with chemotherapy‐induced peripheral neuropathy: A mediation effect analysis by Ling‐Chun Lu, Shiow‐Luan Tsay, Sou‐Yi Chang, Chung‐Ming Chen, Chieh‐Yu Liu

“…This was a cross‐sectional relative study in which four instruments were used: the Neuropathic Pain Symptom Inventory was used to measure the severity of CIPN; the Screening of Activity Limitation and Safety Awareness scale was used to evaluate RDA; the Profile of Mood States Short Form was used to assess negative mood; and the Functional Assessment Cancer Center Therapy‐Colorectal scale version 4 was used to evaluate QoL. …”
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Implications for cost and access of site-of-service referrals for ancillary medical services in a US Medicaid population: analysis of claims data from Maryland, USA by Maqbool Dada, Simrita Singh, Kelsey J Rydland, Chester Chambers, Vishal Mundlye, Edward Kumian, Kayode Ayodele Williams

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Airway Management in Pan Facial Fracture: An Outcome Analysis of Elective Tracheostomy and Submental Endotracheal Intubation by Vipin Venugopal Nair, Yuvraj Issar, Harmanjot Singh Dhillon, Gurpinder Singh Ghotra, Pranay Pratap, Ayush Mathur, Kamalpreet Singh

“…Demographic data, intraoperative time (IOT), length of hospital stay (LOHS), postoperative pain score at three and seven days, and Vancouver Scar Score (VSS) at 4 and 12 weeks was compared between the two groups. …”
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Mechanism of Tai Chi Chuan in Improving Knee Osteoarthritis from the Perspective of Sports Biomechanics by LIU Longcheng, ZHANG Feng, GAO Pengyi, ZHAO Tianlin, WANG Honghao, LI LIU Yinuo, WANG Jiaying, ZHU Xiangyu

“…Exercise therapy, represented by Tai Chi Chuan, has been proven to have good effective in relieving chronic pain caused by KOA. Long-term practice of Tai Chi Chuan can effectively improve knee and ankle proprioception, enhance dynamic stability and reduce the risk of falls in patients with KOA. …”
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Study protocol for an observational study of cerebrospinal fluid pressure in patients with degenerative cervical myelopathy undergoing surgical deCOMPression of the spinal CORD: th... by Armin Curt, Carl Moritz Zipser, Nikolai Pfender, Jose Miguel Spirig, Michael Betz, Jose Aguirre, Markus Hupp, Mazda Farshad, Martin Schubert

“…Introduction Degenerative cervical myelopathy (DCM) is a disabling spinal disorder characterised by sensorimotor deficits of upper and lower limbs, neurogenic bladder dysfunction and neuropathic pain. When suspected, cervical MRI helps to reveal spinal cord compression and rules out alternative diagnoses. …”
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Distal Radial Artery Access in comparison to Forearm Radial Artery Access for Cardiac Catheterization: A Randomized Controlled Trial (DARFORA Trial) by Yunis Daralammouri, Zaher Nazzal, Yahya S. Mosleh, Heba K. Abdulhaq, Zafer Y. Khayyat, Yousef El Hamshary, Murad Azamtta, Ahmed Ghanim, Fateh Awwad, Sajed Majadla, Mosab Maree, Jihad Hamaida, Yahia Ismail

“…The DRA group had a longer puncture duration and a higher number of attempts (duration: 56.6 ± 61.1 s DRA vs. 20.0 ± 18.4 s FRA, p<0.001, attempts: 1.9 ± 1.3 DRA vs. 1.2 ± 0.60 FRA, p<0.001). Puncture-associated pain was greater in the DRA group (4 ± 2.2 DRA vs. 3 ± 2.1 FRA, p=0.001). …”
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Levobupivacaine versus ropivacaine for brachial plexus block: A systematic review and meta-analysis of randomised controlled trials by Abdullah M. Alharran, Muteb N. Alotaibi, Yaqoub Y. Alenezi, Yousef M. Alharran, Ahmad A. Alahmad, Abdulmuhsen Alqallaf, Mohammad F. Al-Mutairi, Abdulbadih R. Saad, Mohammed H. Alazemi, Duaij S. Saif, Ebraheem Albazee, Ahmad Y. Almohammad

“…However, there was no difference between both groups in time to sensory block [MD: −0.30 (95% CI: −1.31, 0.71), P = 0.56], time to motor block [MD: −0.29 (95% CI: −1.26, 0.67), P = 0.55], pain score [MD: −0.48 (95% CI: −2.13, 1.16), P = 0.56], rescue analgesia rate [RR: 0.94 (95% CI: 0.74, 1.20), P = 0.64], and complications [RR: 0.47 (95% CI: 0.20, 1.13), P = 0.09]. …”
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A meta-analysis and systematic review of the clinical efficacy and safety of platelet-rich plasma combined with hyaluronic acid (PRP + HA) versus PRP monotherapy for knee osteoarth... by Dan Du, Yuan Liang

“…Conclusion This meta-analysis reveals that, for patients with KOA, PRP + HA therapy is safe and yields better outcomes in pain relief and functional improvement compared to PRP monotherapy.…”
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Factors associated with hospital length of stay in patients with thoracic hydatid cyst disease undergoing surgical intervention: a retrospective study by Reza Ershadi, Mohammadreza Salehi, Ghazal Roostaei, Niloofar Khoshnam Rad, Sara Soltanmohammadi, Hesam Amini

“…The most common symptom was cough (39.3%), followed by chest pain and dyspnea. Right lower lobe involvement (51.4%) and synchronous liver cysts (13.6%) were frequently observed. …”
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Long-term indwelling trans-anal ileus tube placement and nursing management for an elderly patient with intestinal obstruction (1例高龄肠梗阻患者长期留置经肛型肠梗阻导管的护理体会)... by ZHANG Jia (张佳), SUN Xin (孙鑫)

“…The key points of care are to improve the fixing method to prevent the tube dislocation; Protect the skin and prevent the occurrence of pressure ulcers; Keep the tube unobstructed to ensure effective drainage; Develop a diet plan to meet nutritional intake; Exercise reasonably to prevent complications; Strengthen psychological care and promote the recovery of the patient. The abdominal pain and bloating symptoms had been relieved after treatment and nursing by multi-disciplinary team, and the trans-anal ileus tube had been successfully removed. …”
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Promising LOX proteins for cartilage-targeting osteoarthritis therapy by Luca Morici, Eric Allémann, Olivier Jordan, Ines Nikolić

“…It is caused by a progressive degeneration of articular cartilage, causing pain and limited mobility. Among the pathways involved in cartilage homeostasis, “LOX” proteins (referring to three distinct protein families, very often confused in the literature) play a prominent role. …”
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A qualitative study exploring experiences of treatment in paediatric rheumatology - children’s, young people’s, parents’ and carers’ perspectives by Kassie Gracella Putri, Sunil Sampath, Charlotte Lucy Richardson, Alice McCloskey, Adam Pattison Rathbone

“…Behaviours were influenced through somatic factors (pain, function), social factors (advice from health professionals, encouragement from friends, family and teachers, practicality of using treatment in relation to school, work and finance) and cognitive factors (fear of needles, fear of specific medications, beliefs about necessity). …”
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Evaluation of the Effect of “Honey Zufa” Herbal Syrup on Cough in Hospitalized Patients With COVID-19: A Double Blind Randomized Clinical Trial by Marziyeh Heydari, Hossein Kazemi Zadeh, Soha Namazi, Hamid Emadi Koochak, Nasim Khajavi Rad, Mahnaz Khanavi, Arman Zargaran

“…This symptom significantly diminishes quality of life, causing fatigue, insomnia, dysphonia, musculoskeletal pain, and urinary incontinence. Honey Zufa herbal syrup is a well-known antitussive remedy in the Iranian market and was evaluated for its potential to alleviate this symptom. …”
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Comparative Study on Recovery and Post-Operative Analgesic Efficacy from Fentanyl- Versus Dexmedetomidine-Based Anesthesia in Head and Neck Cancer Surgery by Liza Mohanty, Ravi Kumar, Deepak Tugave, Anagha Agrawal, Sejal Patel, Monika Tanwar, Lalit Patil

“…Recovery profiles were assessed using the Modified Aldrete Score, and post-operative pain was evaluated using the Visual Analog Scale (VAS) at 1, 6, 12, and 24 hours post-surgery. …”
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Altered Brain Activity and Effective Connectivity within the Nonsensory Cortex during Stimulation of a Latent Myofascial Trigger Point by Xinglou Li, Meiling Luo, Yan Gong, Ning Xu, Congcong Huo, Hui Xie, Shouwei Yue, Zengyong Li, Yonghui Wang

“…Myofascial trigger point (MTrP), an iconic characteristic of myofascial pain syndrome (MPS), can induce cerebral cortex changes including altered cortical excitability and connectivity. …”
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Percutaneous Compression Plate versus Dynamic Hip Screw for Treatment of Intertrochanteric Hip Fractures: A Meta-Analyse of Five Randomized Controlled Trials by Lei Zhang, Jie Shen, Shengpeng Yu, Qiang Huang, Zhao Xie

“…Percutaneous compression plating (PCCP) has been advocated to reduce blood loss, relieve pain, and lead to faster rehabilitation for the treatment of intertrochanteric fractures. …”
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A Review on Bioactive Phytochemical Constituents and Pharmacological Activities of Aegiceras corniculatum: A Pharmaceutically Important Mangrove Plant by Pritam Sarkar, Tasfiya Rufaidah Ahnaf, Razina Rouf, Jamil Ahmad Shilpi, Shaikh Jamal Uddin

“…The various parts of this plant have been used in traditional medicinal systems for their potential therapeutic effects in conditions such as asthma, microbial infections, diabetes, pain relief, inflammation, cancer, and arthritis. …”
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Diagnostic Challenges and Innovations in Thoracic Endometriosis (TE) by Julia Bałoniak, Zofia Szymańska, Agnieszka Leszyńska, Zuzanna Bałoniak, Aleksandra Jonkisz, Gabriela Skurzyńska, Aleksandra Stremel, Michalina Doligalska

“…Timely intervention also reduces the burden of chronic pain and improves quality of life, enabling more effective management of this underdiagnosed condition. …”
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Exploration of analgesic and anthelmintic activities of Artocarpus chaplasha ROXB. leaves supported by in silico molecular docking by S M Sohag, Sharmin Nur Toma, Md. Niaj Morshed, Md. Al Imran Imon, Md. Monirul Islam, Md. Ibnul Piash, Naznin Shahria, Imran Mahmud

“…Our present study suggests that Aartocarpus chaplasha leaves can be a potential source of lead compounds for pain management and helminth infections and further advanced investigations are required in the future.…”
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