Bilateral foot drop caused by T12 infectious spondylitis after vertebroplasty: a case report by Dong Hwan Kim, Yong Beom Shin, Mahnjeong Ha, Byung Chul Kim, In Ho Han, Kyoung Hyup Nam

“…A 69-year-old male patient presented with sudden-onset severe bilateral leg pain and bilateral foot drop. Radiologic findings revealed T12 spondylitis compressing the conus medullaris. …”
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Holocord syringomyelia in 18 dogs by Despoina Douralidou, Lorenzo Mari, Sophie Wyatt, Juan Jose Minguez, Patricia Alvarez Fernandez, Carlo Anselmi, Christoforos Posporis

“…Signs of myelopathy attributed to HSM were detected in 12 dogs (67%), spinal pain/paresthesia/allodynia in eight (44%), and four dogs (22%) had no HSM-associated signs. …”
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The pathomechanism of bone marrow edema in the femoral head necrosis with pericollapse stage by Liang Mo, Zhangzheng Wang, Mengyu Jiang, Chi Zhou, Chao Ma, Yinuo Fan, Wei He, Zhenqiu Chen, Yuhao Liu

“…Abstract Bone marrow edema (BME), a notable manifestation during the progression of osteonecrosis of the femoral head (ONFH), exhibits significant associations with femoral head collapse, pain, and prognosis, howeverits’ pathogenesis remains underexplored. …”
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Integrating Clinimetric and Psychometric Approaches in Enhancing Osteoarthritis Care by Roxana Maria Sânziana Pavel, Andrei-Flavius Radu, Delia Carmen Nistor-Cseppento, Cosmin-Mihai Vesa, Anamaria Lavinia Purza, Delia Mirela Tit, Ada Radu, Simona Gabriela Bungau

“…The WOMAC and KOOS are among the clinimetric instruments that offer valuable insights into physical function, stiffness, and pain. By integrating clinimetric and psychometric tools, a comprehensive approach to managing OA is provided, which identifies both physical and mental health need. …”
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The Role of Interpersonal Relationships in Adolescents' Suicidal Behavior: A Qualitative Analysis of Semi-Structured Interviews by N.A. Polskaya, D.K. Yakubovskaya, D.A. Sharova, A.Ya. Basova

“…The first superordinate theme, <em>psychological distress</em>, includes the subthemes of &ldquo;negative thoughts and emotions&rdquo;, &ldquo;mental pain&rdquo; and &ldquo;fear of surviving&rdquo;. …”
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Clinical and laboratory characteristics of solitary rectal ulcer syndrome: a retrospective analysis of 36 case by Furkan Ali Uygur, Muhammed Emin Göktepe, Gökhan Aydın, Enes Ağırman, Ahmet Cumhur Dülger

“…Hematochezia was identified as the most common initial symptom (61.1%), followed by abdominal pain (16.7%) and constipation (11.1%). Laboratory findings revealed significant abnormalities, including mean hemoglobin levels of 10.0 ± 2.4 g/dL and mean CRP levels of 56.7 ± 65.4 mg/L. …”
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Characteristics and Management of Uncontrolled Gout Prior to Pegloticase Therapy: A 2-year Claims Analysis by Robert J. Morlock, Deepan Dalal, Victoria Divino, Mitchell DeKoven, Stephanie D. Taylor, Atsuko Powers, Naina Barretto, Robert J. Holt, Brian LaMoreaux

“…Abstract Objective Gout is a progressive form of arthritis that causes significant pain and disability. Patients with treatment-refractory (or uncontrolled) gout experience a higher prevalence and severity of comorbidities than those whose gout is controlled. …”
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Ectopic Pregnancy: A Review of Prevalence, Clinical Presentation and Outcome in Gusau, Northwest, Nigeria by Shittu MA, Olaoye SO, Aremu-Kasumu YB, Fasanu OT

“…Amenorrhea, abdominal pain and vaginal bleeding were the most common presentations (100%, 98.4% and 96.9% respectively). …”
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Robot-assisted PFNA surgery improves clinical outcomes in the treatment of unstable femoral intertrochanteric fractures in elderly patients compared with traditional PFNA surgery by Chaolong Lu, Xiao Wei, Lugen Li, Wenxing Lan, Penghuan Wu, Qingyang Hu, Wenhu Li, Qiang Wu, Yunze Kang, Zhengbo Hu

“…The observed indicators included visual analog pain scale (VAS) score, surgery time, PFNA operation time, tip-apex distance (TAD), intraoperative blood loss (IBL), perioperative hidden blood loss (PHBL), postoperative allogeneic blood transfusion rate (PABTR), hospital stay, time to first independent walking with crutches postoperatively, time to independent walking without crutches, and Harris hip function score (HHFS). …”
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Factors associated with ABCDEF bundle implementation for critically ill patients: An international cross-sectional survey in 54 countries by Junpei Haruna, Takeshi Unoki, Keibun Liu, Kensuke Nakamura, Shigeaki Inoue, Osamu Nishida

“…Common factors associated with the implementation among all income levels were a multidisciplinary team approach for Element A (pain) and mechanical ventilation use for Element C (sedation), which were also associated with lower Element E (mobility). …”
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Comparison of Glenohumeral Range of Motion Deficits in Youth, Collegiate, and Professional Baseball Players by C. Luke Wilcox, Hillary A. Plummer, Roger V. Ostrander III

“…Individuals with current pain in the arm, shoulder, elbow or shoulder surgery within the prior two years were excluded. …”
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Gut dysbiosis was inevitable, but tolerance was not: temporal responses of the murine microbiota that maintain its capacity for butyrate production correlate with sustained antinoc... by Izabella Sall, Randi Foxall, Lindsey Felth, Soren Maret, Zachary Rosa, Anirudh Gaur, Jennifer Calawa, Nadia Pavlik, Jennifer L. Whistler, Cheryl A. Whistler

“…The therapeutic benefits of opioids are compromised by the development of analgesic tolerance, which necessitates higher dosing for pain management thereby increasing the liability for drug dependence and addiction. …”
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Single postoperative infusion of zoledronic acid to improve patient-reported outcome after hip or knee replacement: study protocol for a randomised, controlled, double-blinded clin... by Jonas Ranstam, Jörg Schilcher, Ewa Roos, Jonathan Brandt, Håkan Ledin, Per Aspenberg

“…Introduction In Sweden, roughly 3000 patients are reoperated each year due to pain and loss of function related to a loosened hip or knee prosthesis. …”
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Functional Outcome (Short Term) of Modular Cementless Bipolar HemiArthroplasty (Hydroxyapatite-Coated Stem) for Fracture Neck of Femur in the Elderly by Navin K. Shukla, Lata Keshkar, Jayanta Mukherjee, Ratnesh Kumar, Shivendra Singh, Alok C. Agrawal

“…Twenty-seven patients (62%) were absolutely pain-free. There were no dislocations, revisions, or additional surgeries in any patients. …”
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Differential Gene Expression Analysis in a Lumbar Spinal Stenosis Rat Model via RNA Sequencing: Identification of Key Molecular Pathways and Therapeutic Insights by Jin Young Hong, Wan-Jin Jeon, Hyunseong Kim, Changhwan Yeo, Hyun Kim, Yoon Jae Lee, In-Hyuk Ha

“…Background/Objectives: Lumbar spinal stenosis (LSS) is a degenerative condition characterized by the narrowing of the spinal canal, resulting in chronic pain and impaired mobility. However, the molecular mechanisms underlying LSS remain unclear. …”
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Alterations in genes associated with cytosolic RNA sensing in whole blood are associated with coronary microvascular disease in SLE by Lihong Huo, Arati Naveen Kumar, Gantsetseg Tumurkhuu, Moumita Bose, Daniel S. Berman, Daniel J. Wallace, Janet Wei, Mariko Ishimori, C. Noel Bairey Merz, Caroline Jefferies

“…Abstract Systemic lupus erythematosus (SLE) patients are 90% women and over three times more likely to die of cardiovascular disease than women in the general population. Chest pain with no obstructive cardiac disease is associated with coronary microvascular disease (CMD), where narrowing of the small blood vessels can lead to ischemia, and frequently reported by SLE patients. …”
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Cannabis in cosmetics: regulatory and scientific insights into hemp seed extracts for skincare by Abhilash Aditya, Too Jae Min, Sornkanok Vimolmangkang, Namsoo P. Kim

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Exoscope-assisted spine surgery: Current applications and future directions–A short review by Tomas Ferreira, Sakshi Roy, Joecelyn Kirani Tan, Wireko Andrew Awuah, Vallabh Shet, Favour Tope Adebusoye, Adrenito Nicolas, Toufik Abdul-Rahman

“…Spine surgery is a critical field that seeks to alleviate pain and restore function in patients with various spinal pathologies. …”
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Osteoarthritis of the knee joint and its association with metabolic syndrome: A case control study by Rohini Motwani, Arvind Kumar Bodla, Shravan Kumar Peddamadyam, Mrudula Chandrupatla, Nagesh Cherukuri, Maheshwar Lakkireddy, Gunvanti Rathod, Sai Ram Challa, Chowdavarapu Raghavendra Rao, Abhishek Arora, Srikanth Eppakayala, Arcot Reddy Vamsi Krishna

“…Background: Osteoarthritis of the knee joint (OAK) represents a leading cause of pain, functional limitation, and diminished quality of life, particularly among older adults. …”
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Barriers to Physical Activity in East Harlem, New York by Ashley M. Fox, Devin M. Mann, Michelle A. Ramos, Lawrence C. Kleinman, Carol R. Horowitz

“…The most commonly reported perceived barriers to physical activity identified by nearly half of the sample were being too tired or having little energy followed by pain with exertion and lack of time. Multivariate regression found that individuals who endorsed a greater number of perceived barriers were less likely to report having met their weekly recommended levels of physical activity and less likely to engage in recreational physical activity controlling for covariates. …”
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