Protocol and statistical analysis plan for the PREventing cardiovascular collaPse with Administration of fluid REsuscitation during Induction and Intubation (PREPARE II) randomised... by Li Wang, Tamer Hudali, Shekhar Ghamande, Megan Moore, Bruno Pereira, Christopher J Lindsell, Wesley H Self, Todd W Rice, Matthew W Semler, Kate O’Connor, David B Page, Victor E Ortega, Aaron M Joffe, Swati Gulati, G Patel, Heath D White, Muhammad Ali, Jonathan D Casey, David R Janz, Derek W Russell, Derek J Vonderhaar, Kevin M Dischert, William S Stigler, Emily Adams, Kevin W Gibbs, James M Dargin, A M Joffe, Akram Khan, Simanta Dutta, Janna S Landsperger, Sarah W Robison, Itay Bentov, Joanne M Wozniak, Susan Stempek, Olivia F Krol, Matthew E Prekker, Brian E Driver, Joseph M Brewer, Christopher John Lindsell, David Janz, Stephen P Peters, Rita N Bakhru, Scott Bauer, Christina R Bellinger, Amanda M Brown, Blair Brown, Jerri Brown, Caitlin Bumgarner, Wendy Butcher, Megan Caudle, Arjun B Chatterjee, David J Chodos, Gerardo Corcino, Nathan S Cutler, Travis L Dotson, Daniel C Files, Jonathan L Forbes, John P Gaillard, Katherine A Gershner, Shannon Ginty, Kiadrick R Hood, April Hazelwood, Katherine Hendricks, Kelly Jacobus, Jonathan T Jaffe, Stacy Kay, Chad A Kloefkorn, Jennifer Krall, Margo T Lannan, Cornelia Lane, Cynthia Lanning, Jessica Lyons, William I Mariencheck, Chad R Marion, Matthew A Maslonka, Sara McClintock, Nathaniel M Meier, Matthew C Miles, Peter J Miller, Sophia Mitchell, Wendy C Moore, Katherine Moss, Andrew M Namen, Dustin L Norton, Stella B Ogake, Jill A Ohar, Jessica A Palakshappa, Rodolfo M Pascual, Sandi Pascual, Aaron Pickens, Adam R Schertz, Matt Strong, Alexander O Sy, Braghadheeswar Thyagarajan, Amy Townsend, Russell Worthen, Michael Wlodarski, Charles Yarbrough, Caroline York, Bradley Lloyd, James Dargin, Joanne Wozniak, Christopher Adler, Ahmed Agameya, Michael Colancecco, Daniel Fitelson, Joshua Giaccotto, Gena Han, Louise Kane, Ezra Miller, Timothy Noland, Jaqueline Price, Joseph Plourde, Fraser Mackay, Laura Mahoney, Avignat Patel, Michael Plourde, Zena Saadeh, Sara Shadchehr, Sandeep Somalaraju, Eleanor Summerhill, Ryan Webster, Jordan Winnicki, Ekaterina Yavarovich, Sheetal Gandotra, Anna Altz-Stamm, Cristina Bardita, Mary Clay Boone, Joe W Chiles, Kristina Collins, Abby Drescher, Kevin G Dsouza, Janna Dunn, Stacy Ejem, Josh Gautney, Nicole Harris, Savannah Herder, R Chad Wade, Rutwij Joshi, Daniel Kelmenson, Anne Merrill Mason, Scott R Merriman, Takudzwa Mkorombindo, Jada Nowak, D Sheylan, Lisa Sarratt, Tabitha Stewart, Kadambari Vijaykumar, Gina White, Micah R Whitson, Christopher Barnes, Andrew M Walters, Alejandro C Arroliga, Tasnim Lat, Stephanie Nonas, Milad K Jouzestani, Raya Adi, Chandani Anandkat, Hanae Benchbani, Matthew G Drake, Makrina N Kamel, Ramanpreet Randhawa, Jessica L Tsui

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Types of discomfort and pre-hospital interventions administered to trauma victims: scoping review protocol by Filipe Melo, Mauro Mota, Margarida Reis Santos, Miguel Castelo Branco

“… Introduction: Trauma is a leading cause of death and disability worldwide. In addition to acute pain caused by trauma, victims often face discomforts during pre-hospital care, such as cold, anxiety, and fear, which may worsen their condition and hinder care. …”
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Comparative Effectiveness of Remestemcel-L-rknd versus Ruxolitinib in Pediatric Patients with Steroid-Refractory Acute Graft-Versus-Host Disease using Simulated Treatment Compariso... by Gabriel Tremblay, Dimitrios Tomaras, Eric Strati, Anna Forsythe

“…Remestemcel-L-rknd was also associated with improved safety outcomes (_P_<0.05) in 17 out of 30 AEs, including hematologic events, peripheral edema, muscular weakness, nausea, back pain, and fatigue. **Conclusion:** Remestemcel-L-rknd was associated with significant improvements in day 28 ORR compared with ruxolitinib in patients with severe (grade III-IV) SR aGVHD. …”
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Balloon Cell Urethral Melanoma: Differential Diagnosis and Management by M. McComiskey, C. Iavazzo, M. Datta, R. Slade, B. Winter-Roach, G. Lambe, V. K. Sangar, M. Smith

“…A 76-year-old lady presented with vaginal pain and discharge. On examination, a 4 cm mass was noted in the vagina and biopsy confirmed melanoma of a balloon type. …”
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Antipleuritic and Vascular Permeability Inhibition of the Ethyl Acetate-Petroleum Ether Stem Bark Extract of Maerua angolensis DC (Capparaceae) in Murine by Felix Agyei Ampadu, Eric Boakye-Gyasi, Newman Osafo, Charles Kwaku Benneh, Edmund Ekuadzi, Eric Woode

“…Maerua angolensis has been used traditionally in the management of pain, arthritis, and rheumatism in Ghana and Nigeria but no scientific evidence is currently available to give credence to its folkloric use. …”
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Regenerative properties of bone marrow mesenchymal stem cell derived exosomes in rotator cuff tears by Junjie Chen, Zihe Wang, Ming Yi, Yi Yang, Mengzhao Tian, Yinqi Liu, Guoyou Wang, Huarui Shen

“…Abstrct Rotator cuff injury (RCI), characterized by shoulder pain and restricted mobility, represents a subset of tendon-bone insertion injuries (TBI). …”
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Cystitis glandularis due to Escherichia coli infection in a diabetic Miniature Schnauzer: a case report by J. P. Rey Amunategui, D. Echeverria, A. Duchene

“…After initiation of antibiotic therapy and pain management, the dog's clinical signs improved markedly until complete remission of the bladder lesions. …”
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The Safety and Efficacy of Chemical Pleurodesis Agents in Patients with Malignant Pleural Effusion Admitted in Tertiary Care Hospital by Venkateshwaran Kathamuthu, Rajeshkumar Balakrishnan, Saravanavasan Rajendran, Prabhakaran Rathinam

“…Background: Pleurodesis alleviates symptoms such as dyspnea, chest pain, cough and prevents recurrent pleural collections which require repeated thoracentesis. …”
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Changes in Shoulder and Lumbar Injury Incidence in Swimmers After Physical Examination and Exercise Programs by Hiroki Takayama, Masatoshi Nakamura, Satoshi Kataura, Shinya Kazekami, Ryosuke Takane, Yosuke Mitomi, Shigeto Nakagawa

“…Previous injury was considered as pain that lasted for > three weeks or that caused the participant to stop practicing. …”
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The potential of polyphenol compounds in grapes to reduce oxidative stress and inflammation after exercise: systematic review by Novadri Ayubi, Atika Syafawi, Anton Komaini, Dhea Regita Sastika Putri, Ilham Ilham, Deby Tri Mario, Dyah Fitria Padmasari, Junian Cahyanto Wibawa, Procopio B. Dafun Jr.

“…Besides, the grapes have anti-inflammatory properties, which are responsible for lowering uncontrolled inflammation and alleviating muscle pain fierceness. …”
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The pharmacology, toxicology, and detoxification of Aconitum kusnezoffii Reichb., traditional and modern views by Kenneth Happy, Sungyu Yang, Chang Ho Kang, Youngmin Kang

“…These compounds exhibit various pharmacological activities including anti-inflammatory, analgesics, anti-cancer, anti-tumor, anti-arhythmic and pain-relieving properties. Despite its therapeutic potential, A. kusenzoffii. has narrow therapeutic window, meaning even small doses can be toxic. …”
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A Unique and Rare Presentation of Adult Congenital Heart Disease: Common Atrium Associated with Coronary Aneurysms and Fistula by Muhammad Shabbir Rawala, Alex Munoz, Mohammad Hassan Pervaiz

“…A 60-year-old female patient presented with substernal chest pain. The nuclear stress test showed no reversible ischemia; however, right ventricle (RV) dilation was present. …”
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Assessing the relationship between wrist synovitis and anxiety: a study using clinical statistics and Mendelian randomization analysis by Xunhao Wang, Linyi Zhu, Jingyi Mi, Fei Xiong

“…Abstract Background Wrist synovitis often leads to persistent pain, swelling, and limited mobility, causing significant functional impairment and psychological distress, including anxiety. …”
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Waveform characteristics in thoracic paravertebral space: a prospective observational study [version 2; peer review: 2 approved] by Pattika Subsoontorn, Lalinthip Vareesunthorn, Amorn Vijitpavan, Sivaporn Termpornlert

“…After completion of the surgery, the extent of dermatomal blockade and the pain score was assessed in all patients. Results 98 typical regular respiratory waveforms with a mean pressure of ≤ 25 mmHg were detected in the TPVS of 50 patients. …”
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Exploring the most important factors related to self-perceived health among older men in Sweden: a cross-sectional study using machine learning by David C Currow, Magnus Per Ekström, Max Olsson

“…Importance of factors was measured in SHapley Additive exPlanations absolute mean and higher scores correspond to greater importance.Results The most important factors for classifying self-perceived health were: pain (0.629), sleep quality (0.595), breathlessness (0.549), fatigue (0.542) and depression (0.526). …”
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Ureteric Trauma following Stent Removal in Kidney Transplant Recipient: A Unique Case of Prolonged Morbidity by Ahmad Mirza, Imran Gani, Andy Shi Huang, Ravi Mallavarapu, Laura Mulloy, Muhammad Saeed, Rajan Kapoor

“…The ureteric stent was removed with flexible cystoscopy on postoperative day (POD) 24. 24 hours later, the patient presented with abdominal pain and inability to urinate. An urgent ultrasound and noncontrast CT scan showed grade 4 hydronephrosis of the transplanted kidney. …”
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Probable Hydrochlorothiazide-Induced Myopericarditis: First Case Reported by Toufik Mahfood Haddad, Muhammad Sarfraz Nawaz, Ahmed S. Abuzaid, Smrithy Upadhyay, Pallavi Bellamkonda, Aryan N. Mooss

“…An African American female, with past history of hypertension, coronary artery disease, and sulfa allergy, presented with indolent onset and retrosternal chest pain which was positional, pleuritic, and unresponsive to sublingual nitroglycerin. …”
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Radiological, Clinical, and Histological Findings in the Treatment of Pilonidal Sinus with Phenol Injection by Tonguc Utku YILMAZ, Omer YAVUZ, Ahmet Oktay YIRMIBESOGLU, Hasan Tahsin SARISOY, Cigdem VURAL, Umay KIRAZ, Nihat Zafer UTKAN

“…Objective: Sacrococcygeal pilonidal disease is a chronic discharging wound that causes pain and loss of quality of life. Phenol application is an outpatient procedure with low complications and low recurrence rates. …”
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Nursing of a patient with infertility caused by chronic pelvic inflammatory disease treated with the Chinese herbal medicine ointment rubbing therapy (中药膏摩治疗1例慢性盆腔炎所致不孕症的护理体会)... by TENG Yue (滕悦), LU Ying (卢英), WANG Xuejing (王雪静), YANG Man (杨曼)

“…Based on the Traditional Chinese Medicine syndrome differentiation and nursing assessment, the Chinese herbal medicine rubbing therapy and comprehensive nursing interventions such as dietary care, emotional care and life support were carried out to relieve the pain and anxiety, and improve the absorption of pelvic inflammatory effusion. …”
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Splenic Artery Pseudoaneurysm Presenting as Massive Hematemesis: A Diagnostic Dilemma by Peeyush Varshney, Bhupen Songra, Shivank Mathur, Sudarshan Gothwal, Puneet Malik, Mahnedra Rathi, Rajveer Arya

“…We present a case of 38-year-old male admitted with chief complaints of pain in the upper abdomen and massive hematemesis for the last 15 days. …”
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