Dioscin from Polygonatum sibiricum induces apoptosis and autophagy in Ishikawa human endometrial cancer cell and in vivo by Xiaoli Li, Runhui Ma, Zhijing Ni, Wei Wang, Kiran Thakur, Jianguo Zhang, Zhaojun Wei

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Hesperidoside abolishes dichlorvos-mediated neurotoxicity in rats by suppressing oxidative stress, acetylcholinesterase inhibition, and NF-κB-p65/p53/caspase-3-mediated apoptosis by Adio J. Akamo, Adetutu O. Ojelabi, Oluwatobi T. Somade, Iyabode A. Kehinde, Adewale M. Taiwo, Boluwatife A. Olagunju, Mushafau A. Akinsanya, Adedayo A. Adebisi, Tobi S. Adekunbi, Abiola F. Adenowo, Florence Anifowose, Olufemi M. Ajagun-Ogunleye, Ofem E. Eteng, Jacob K. Akintunde, Regina N. Ugbaja

“…Conclusion: HESP chemotherapeutic interventions enhanced cerebral functions in DDVP-treated rats by abrogating oxidative stress, acetylcholinesterase inhibition, and NF-κB-p65/p53/caspases-3 signaling.…”
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Palmitic Acid Methyl Ester Induces G2/M Arrest in Human Bone Marrow-Derived Mesenchymal Stem Cells via the p53/p21 Pathway by Jian-Hong Lin, Pei-Ching Ting, Wen-Sen Lee, Hung-Wen Chiu, Chun-An Chien, Chin-Hung Liu, Li-Yi Sun, Kun-Ta Yang

“…Moreover, the half-life of p53 protein was prolonged in the PAME-treated hBM-MSCs. …”
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Investigation into the influence of mild hypothermia on regulating ferroptosis through the P53-SLC7A11/GPX4 signaling pathway in sepsis-induced acute lung injury by Liujun Tao, Jie Xu, Liangyan Jiang, Juntao Hu, Zhanhong Tang

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实时荧光定量 PCR检测野生型p53介导蛋白磷酸酶mRNA 在非小细胞肺癌中的表达

“…【目的】 荧光染料Ⅰ(SYBR GreenⅠ)是一种较为常用的非探针类定量PCR的方法,其结果具有一定特异性65377;本研究的目的是建立检测野生型p53介导蛋白磷酸酶(Wip1)mRNA的SYBR GreenⅠ实时定量PCR的方法,了解肺癌组织及其远癌正常肺组织中Wip1的表达水平,研究肺癌组织中Wip1的表达水平与各种临床病理特征之间的关系65377; 【方法】 利用相对定量的方法检测44例肺癌及相应远癌正常肺组织中Wip1 mRNA相对于β-actin mRNA的表达量,进行相对定量分析65377; 【结果】 44例非小细胞肺癌(NSCLC)及相应远癌正常肺组织均有Wip1 mRNA的表达,其中17例非小细胞肺癌中Wip1 mRNA高表达,占38.6%,两者表达差异有统计学意义 (Ratio = 2.1644 ± 1.394,P < 0.05);分化程度低的肺癌组织中Wip1 mRNA表达量显著高于分化程度高者(F = 5.08,P = 0.013)65377; 【结论】 SYBR GreenⅠ实时定量PCR方法可以成功地检测Wip1基因的表达量65377;初步检测结果显示Wip1可能是一种肺癌发生发展过程中的致癌因素65377;…”
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Retracted: CuO-TiO2-Chitosan-Berbamine Nanocomposites Induce Apoptosis through the Mitochondrial Pathway with the Expression of P53, BAX, and BCL-2 in the Human K562 Cancer Cell Line by Bioinorganic Chemistry and Applications

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[Retracted] CuO-TiO2-Chitosan-Berbamine Nanocomposites Induce Apoptosis through the Mitochondrial Pathway with the Expression of P53, BAX, and BCL-2 in the Human K562 Cancer Cell Line by Abozer Y. Elderdery, Badr Alzahrani, Siddiqa M. A Hamza, Gomaa Mostafa-Hedeab, Pooi Ling Mok, Suresh Kumar Subbiah

“…Flow cytometry was also employed to identify pro- and antiapoptotic proteins such as Bcl2, Bad, Bax, P53, and Cyt C. The FTIR spectrum revealed that the CuO-TiO2-Chitosan-Berbamine nanocomposites were electrostatically interlocked. …”
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A novel approach for target deconvolution from phenotype-based screening using knowledge graph by Xiaohong Wang, Meifang Zhang, Jianliang Xu, Xin Li, Jing Xiong, Haowei Cao, Fangkun Dou, Xue Zhai, Hua Sun

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RETRACTED ARTICLE: Histological, ultrastructural, and biochemical study on the possible role of Panax ginseng in ameliorating liver injury induced by Lambda cyhalotherin by Manal Abdul-Hamid, Hanaa M. Mohamed, Sanaa M. Abd El-Twab, Karim Zaied

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Curcumin nanoparticles alleviate brain mitochondrial dysfunction and cellular senescence in γ-irradiated rats by Omnia A. Moselhy, Nahed Abdel-Aziz, Azza El-bahkery, Said S. Moselhy, Ehab A. Ibrahim

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<i>Eugenia uniflora</i> Effects on the Depressive-like Behavior of MPTP-Exposed Female Rats: Apoptosis and α-Synuclein Modulation by Anne Suély Pinto Savall, Jhuly Dorneles De Mello, Eduarda Monteiro Fidelis, Vandreza Cardoso Bortolotto, Mustafa Munir Mustafa Dahleh, Gustavo Petri Guerra, Marina Prigol, Robson Puntel, Jean Ramos Boldori, Cristiane Casagrande Denardin, Tuane Bazanella Sampaio, Simone Pinton

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人类表皮生长因子、p53、雌激素受体及孕激素受体在 不同临床期别乳腺浸润性导管癌组织中的表达

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Clinical and molecular analysis of JCPyV and BKPyV infection and associated risk of urothelial carcinoma development in the upper tract by Chun-Nun Chao, Chi-Feng Hung, Wei‑Hong Lai, Chun-Liang Tung, Wan-Yun Yeh, Kai-Wu Yang, Meilin Wang, Ya-Yan Lai, Pei-Lain Chen, Cheng-Huang Shen

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Corrigendum to “Inhibition of HIF-2α expression in cardiomyocytes attenuates PCB126-induced cardiotoxicity associated with decreased apoptosis through the PI3K/Akt and p53 signaling pathways” [Ecotoxicol. Environ. Saf. 286 (2024) 117185] by Long Chen, Li-Jian Chen, Hong-Wu Shen, Clare Hsu, Jia-Hao Zeng, Jia-Hao Li, Jia-Li Liu, Jian-Zheng Yang, Yi Liu, Xiu-Wen Li, Xiao-Li Xie, Qi Wang, Dong Zhao

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Function of vasohibin-2 and the mechanism of alternative splicing in triple-negative breast cancer by WANG Wei, WANG Hongli, ALIBIYATI·i Ain, YILIYAER· Rousu, NUER AYI, YANG Liang

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Therapeutic effects of focused ultrasound on vulvar squamous intraepithelial lesions in rat by Yijin Fan, Xi Wang, Yao Liu, Huajun Tang, Chengzhi Li

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Predictive and Prognostic Molecular Markers of Oral Cancers and Potential Therapeutic Agents Targeting These Markers by Shilpa Jain, Anil Goel, Arpita H Patel, Sarvatnida Shaikh

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FN1 shapes the behavior of papillary thyroid carcinoma through alternative splicing of EDB region by Mian Liu, Pei Chen, Bo Wei, Hai-Long Tan, Ya-Xin Zhao, Lei Ai, Ning Li, Ying-Ke Jiang, Jing Lin, Shi-Jin Li, Shi Chang

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Features of expression of immunohistochemical markers in local and generalized clear cell kidney cancer by E. M. Frantsiyants, A. N. Shevchenko, E. A. Dzhenkova, N. S. Karnaukhov, T. A. Gudtskova, A. A. Breus, E. V. Filatova, D. A. Shvyrev

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Change detection in the dynamics of an intracellular protein synthesis model using nonlinear Kalman filtering by Gerasimos G. Rigatos, Efthymia G. Rigatou, Jean Daniel Djida

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