Tumor hypoxia evidences the differential regulation of Mdm2-p53 axis by PTEN in tumor derived vs. normal endothelial cells by Kinga Wilkus-Adamczyk, Klaudia Brodaczewska, Claudine Kieda

Subjects: “…Mdm2-p53…”
Get full text

Dendritic cell maturation is induced by p53-armed oncolytic adenovirus via tumor-derived exosomes enhancing systemic antitumor immunity by Tomoko Ohtani, Shinji Kuroda, Nobuhiko Kanaya, Yoshihiko Kakiuchi, Kento Kumon, Masashi Hashimoto, Chiaki Yagi, Ryoma Sugimoto, Satoru Kikuchi, Shunsuke Kagawa, Hiroshi Tazawa, Yasuo Urata, Toshiyoshi Fujiwara

Subjects: Get full text

p53 基因蛋白在大肠腺瘤中的表达#br# 及其与细胞增殖的关系 by 文卓夫　袁世珍

Subjects: Get full text

Key Roles of p53 Signaling Pathway-Related Factors GADD45B and SERPINE1 in the Occurrence and Development of Gastric Cancer by Yaoqing Li, Liyijing Shen, Kelong Tao, Guangen Xu, Kewei Ji

“…p53 can function as an independent and unfavorable prognosis biomarker in cancer patients. …”
Get full text

Mismatch repair, p53, and L1 cell adhesion molecule status influence the response to chemotherapy in advanced and recurrent endometrial cancer by Jung Chul Kim, Byungsoo Ahn, Yong Jae Lee, Eun Ji Nam, Sang Wun Kim, Sunghoon Kim, Young Tae Kim, Eunhyang Park, Jung-Yun Lee

“…Results Of the 156 patients, 62 (39.7%), 53 (34.0%), and 41 (26.3%) had p53wt/pMMR, abnormal p53 (p53abn), and MMR-deficient (dMMR) tumors, respectively. …”
Get full text

中药胃康宁对实验性胃癌 PCNA、 p53 蛋白表达的干预作用#br# by 余　谦

“…【结论】胃康宁对大鼠实验性胃癌 具有良好的防治作用,此作用与降低 PCNA、p53 蛋白表达有关。…”
Get full text

Morphological and immunohistochemical analysis in encapsulated follicular variant papillary thyroid carcinoma, invasive follicular variant papillary thyroid carcinoma and a new ent... by Zeliha Çelik, Naile Kökbudak, Fahriye Kilinç, Pembe Oltulu

Subjects: “…p53…”
Get full text

Ginger polysaccharide UGP1 suppressed human colon cancer growth via p53, Bax/Bcl-2, caspase-3 pathways and immunomodulation by Yanfang Qian, Chenying Shi, Chen Cheng, Dengwei Liao, Junping Liu, Gui-tang Chen

Subjects: Get full text

<italic>p53</italic>及<italic>EGFR</italic>与头颈部鳞癌放疗抵抗的关系 by 代永杰, 徐钢

Subjects: “…<italic>p53</italic>…”
Get full text

P53 and PIK3CA Mutations in KRAS/HER2 Negative Ovarian Intestinal-Type Mucinous Carcinoma Associated with Mature Teratoma by Sarah Bouri, Philippe Simon, Nicky D’Haene, Xavier Catteau, Jean-Christophe Noël

“…We report here the first case of mucinous ovarian tumor in which mutation of the PIK3CA and P53 genes could be demonstrated by the next generation sequencing technique without KRAS mutation or HER2 amplification. …”
Get full text

Role of p16INK4A in Replicative Senescence and DNA Damage-Induced Premature Senescence in p53-Deficient Human Cells by Razmik Mirzayans, Bonnie Andrais, Gavin Hansen, David Murray

“…These observations are made with cells that express wild-type p53, a key mediator of the DNA damage response. …”
Get full text

舌鳞状细胞癌组织中p53 、p21 和bcl-2 基因蛋白的表达 by 潘朝斌

“…【目的】研究p53、p21 和bcl-2 基因蛋白在舌鳞状细胞癌组织中的表达及其临床意义。【方法】用免疫组化SP 法 检测54 例舌鳞状细胞癌组织标本p53、p21 和bcl-2 癌基因蛋白表达。…”
Get full text

Prognostic significance of cell cycle-associated proteins p16, pRB, cyclin D1 and p53 in resected oropharyngeal carcinoma by Michaela Plath, Martina A. Broglie, Diana Förbs, Sandro J. Stoeckli, Wolfram Jochum

Subjects: Get full text

Relationship among Tobacco Habits, Human Papilloma Virus (HPV) Infection, p53 Polymorphism/Mutation, and the Risk of Oral Squamous Cell Carcinoma by Neha Gupta, Gargi Yumnam, Chetan Sharma, Avani Patel, Ripudaman Sharma, Sachin Dev, Mahesh Ghadage

“…Tobacco habits, human papilloma virus (HPV) infection, and p53 polymorphisms or mutations have been implicated in its etiology. …”
Get full text

Early recurrence after surgery in FIGO 2023 stage I-III endometrial cancer: characteristics and risk factors by Zhen Huang, Xue Li, Ling Li

Subjects: Get full text

Prion meeting 2023: implications of a growing field by Tiago F. Outeiro, Tuane C. R. G. Vieira

Subjects: Get full text

Identification of cardiac premature senescence markers through GEO database interaction approach by Tiwuk Susantiningsih, Ani Retno Prijanti, Novi Silvia Hardiany, Fadilah

Subjects: “…p53…”
Get full text

Novel Inhibitors for MDM2-MDM4 E3 Ligase Potently Induce p53-Indepedent Apoptosis in Drug-Resistant Leukemic Cells by Rati Lama, Joseph M. Fose, Diana Martín, Inés G. Muñoz, Eunice S. Wang, Pamela J. Sung, Sherry R. Chemler, Xinjiang Wang

Subjects: Get full text

Deciphering the safeguarding role of cysteine residues in p53 against H2O2-induced oxidation using high-resolution native mass spectrometry by Manuel David Peris-Díaz, Artur Krężel, Perdita Barran

“…Abstract The transcription factor p53 is exquisitely sensitive and selective to a broad variety of cellular environments. …”
Get full text

Immunohistochemical Expression of p53 Gene and Clinicopathological Assessment of Low-grade Serous Ovarian Cancer and High-grade Serous Ovarian Cancer: A Cohort Study by Geeta Bazard, Minakshi Vashist, Sunita Singh, Gulshan Rohilla, Nidhi Paliwal

“…Alteration in functioning of p53 gene has been connected to the onset and spread of ovarian cancer. …”
Get full text