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Expression of VEGF-A, Otx Homeobox and p53 Family Genes in Proliferative Vitreoretinopathy
Published 2013-01-01“…PVR samples showed little or no expression of Otx1 and variable expression of VEGF-A, Otx2, Otx3, p53, and p63 genes. Significant correlation was found among VEGF-A, Otx2, p53, and p63 and between Otx1 and Otx3. …”
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Multicellular model of neuroblastoma proposes unconventional therapy based on multiple roles of p53.
Published 2024-12-01“…It follows that alternating between inhibiting MDM2 to restore p53 activity and inhibiting ARF to attenuate p53 activity is a promising, if unorthodox, therapeutic strategy. …”
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Upregulation of p53 by tannic acid treatment suppresses the proliferation of human colorectal carcinoma
Published 2021-12-01Subjects: Get full text
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P53 and Expression of Immunological Markers May Identify Early Stage Thyroid Tumors
Published 2013-01-01“…TAM was more frequent in P53 negative tumors (P=0.002). Infiltration of CD8+ TIL was found in 61.7% of P53 positive and 25.6% of P53 negative DTC (P<0.001). …”
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KRAS, p53 and BRAF Gene Mutations and Aneuploidy in Sporadic Colorectal Cancer Progression
Published 2006-01-01“…Results: p53, KRAS and BRAF mutations were found in 39%, 34%, and 4% of tumors, respectively. …”
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Study of the expression of oncoprotein p53, EGFR in colorectal carcinomas with different proliferative activity
Published 2023-04-01Subjects: Get full text
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应用非同位素aPCR-SSCP法检测P53基因突变
Published 1994-01-01“…建立一种非同位素的不对称聚合酶链反应-单链构象多态性技术(aPCR-SSCP):通过不对称PCR(aPCR)获得单链,普通PAGE电泳分离,经银染快速准确检出突变;应用这种方法,研究了4株鼻咽癌细胞株CNE1,CNE2,HK1和SUNE1中肿瘤抑制基因P53基因突变,证实CNE1,CNE2在第8外显子,HK1在第5外显子有突变,并发现新建立的细胞株SUNE1存在第8外显子的突变。…”
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Smad1 Promotes Tumorigenicity and Chemoresistance of Glioblastoma by Sequestering p300 From p53
Published 2025-01-01Subjects: Get full text
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To study the expression of estrogen, progesterone receptor and p53 immunohistochemistry markers in subtyping endometrial carcinoma
Published 2023-07-01Subjects: Get full text
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The immunohistochemical evaluation of the expression of intermediary filaments, pcna, p53 and mmp-9 in feline fibrosarcomas
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Loss of p53 Expression in Gastric Epithelial Cells of Helicobacter pylori-Infected Jordanian Patients
Published 2022-01-01“…H. pylori induces the production of reactive oxygen species, DNA damage, and accelerates the degradation of the tumor suppressor protein p53, which may lead to cancer development. In this study, we investigated the relationship between H. pylori infection and the expression of p53 in gastric mucosa in a group of patients from Jordan. …”
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Chronic Alcohol Consumption Attenuates Apoptosis by Down Regulation of P53 Expression in the Rat Pancreas
Published 2001-01-01Get full text
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PIK3CA and p53 Mutations by Next Generation Sequencing in Lymphoepithelioma-Like Carcinoma of the Endometrium
Published 2018-01-01“…Nevertheless, in endometrial lymphoepithelioma-like carcinoma, the alterations on cell cycle, apoptosis, and/or senescence secondary to p53 mutations could potentially be counterbalanced by the antitumoral response induced by CD8 cytotoxic T-lymphocytes numerous in these tumors.…”
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CENPN contributes to pancreatic carcinoma progression through the MDM2-mediated p53 signaling pathway
Published 2024-04-01Subjects: Get full text
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Molecular Signature of miR-34a/NEAT-1/p53 Axis in Mycosis Fungoides
Published 2024-01-01“…Understanding the role of miRNAs and ncRNAs in p53-response has become an open discussion, as they can regulate p53 or its downstream targets, and ncRNAs themselves. …”
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ATRX loss inhibits DDR to strengthen radio-sensitization in p53-deficent HCT116 cells
Published 2025-01-01Subjects: Get full text
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FBR2 modulates ferroptosis via the SIRT3/p53 pathway to ameliorate pulmonary fibrosis
Published 2025-02-01Subjects: Get full text
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The relationship between IDH, P53 mutations, MGMT methylation with characteristics in high grade glioma patients
Published 2022-07-01“…The presence of mutations in IDH, P53 genes, and MGMT methylation status was a beneficial factor for treatment response as assessed by RECIST.…”
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