Crocin Suppresses LPS-Stimulated Expression of Inducible Nitric Oxide Synthase by Upregulation of Heme Oxygenase-1 via Calcium/Calmodulin-Dependent Protein Kinase 4 by Ji-Hee Kim, Ga-Young Park, Soo Young Bang, Sun Young Park, Soo-Kyung Bae, YoungHee Kim

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Impact of Varicocele on The Expression of Testicular Enzymes Involved in The Transsulfuration Pathway by Azam Shiasi, Marziyeh Tavalaee, Ramesh Monajemi, Dattilo M, Mohammad Hossein Nasr-Esfahani

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Genome-Wide Identification and In Silico Expression Analysis of <i>CCO</i> Gene Family in <i>Citrus clementina</i> (Citrus) in Response to Abiotic Stress by Sadaf Sarwar, Adnan Sami, Muhammad Zeshan Haider, Layba Tasawar, Jannat Akram, Arsalan Ahmad, Muhammad Shafiq, Haitham E. M. Zaki, Gabrijel Ondrasek, Muhammad Shafiq Shahid

Subjects: “…carotenoid cleavage oxygenase (CCO)…”
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Early Serum Heme Oxygenase-1, Soluble Vascular Endothelial Growth Factor Receptor-1, and B-Cell Lymphoma/Leukemia-2 Levels and Unfavorable Obstetric Outcomes by Havva Sutcu, G. Fusun Varol, Cihan Inan, Isil Uzun, N.Cenk Sayin

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Heme Oxygenase 1/Peroxisome Proliferator-Activated Receptor Gamma Pathway Protects Intimal Hyperplasia and Mitigates Arteriovenous Fistula Dysfunction by Regulating Oxidative Stress and Inflammatory Response by Tingfei Xie, Yunpeng Xu, Lecai Ji, Xiaolu Sui, Aisha Zhang, Yanzi Zhang, Jihong Chen

“…This study is aimed at exploring the molecular mechanisms underlying AVF development and the roles of the heme oxygenase 1/peroxisome proliferator-activated receptor gamma (HO-1/PPAR-γ) pathway in AVF. …”
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Carbon Monoxide-Releasing Molecule-3 Suppresses Tumor Necrosis Factor-α- and Interleukin-1β-Induced Expression of Junctional Molecules on Human Gingival Fibroblasts via the Heme Oxygenase-1 Pathway by Jia Lv, Yongsheng Liu, Shuhan Jia, Yuna Zhang, Haoyang Tian, Jingyuan Li, Hui Song

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Heme Oxygenase-1-Modified Bone Marrow Mesenchymal Stem Cells Combined with Normothermic Machine Perfusion Repairs Bile Duct Injury in a Rat Model of DCD Liver Transplantation via Activation of Peribiliary Glands through the Wnt Pathway by Xuan Tian, Huan Cao, Longlong Wu, Weiping Zheng, Mengshu Yuan, Xiang Li, Hongli Song, Zhongyang Shen

“…The present study was aimed at exploring the repair effect of heme oxygenase-1- (HO-1-) modified BMMSCs (HO-1/BMMSCs) combined with normothermic machine perfusion (NMP) on bile duct injury after DCD liver transplantation and at revealing the underlying mechanisms. …”
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Mangrove plants using deoxyribonucleic acid barcodes for enhancing biodiversity and conservation by M. Basyuni, R. Syahbana, A.B. Rangkuti, N.A. Pradisty, A. Susilowati, L.A.M. Siregar, S.S. Al Mustaniroh, A.A. Aznawi, A. Mubaraq, E.R. Ardli, S.H. Larekeng, V. Leopardas, Y. Isowa, T. Kajita

“…The primers ribulose 1,5-bisphosphate carboxylase/oxygenase, transfer ribonucleic acid for histidine–photosystem II reaction center protein A, internal transcribed spacer, and maturase-K had the highest success rates during amplification. …”
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Neuroprotective Potentials Of Extracts From Moringa Oleifera And Musa Sapientum Against Cadmium Chloride-Induced Neurotoxicity In Rats Cerebri by Adelaja Akinlolu

“…Tissue concentrations of catalase, superoxide dismutase, cyclo-oxygenase-2 and cytochrome P450 in rats’ cerebri were determined using ELISA. …”
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Exploring microbial players for metagenomic profiling of carbon cycling bacteria in sundarban mangrove soils by Basanta Kumar Das, Ayushman Gadnayak, Hirak Jyoti Chakraborty, Smruti Priyambada Pradhan, Subhashree Subhasmita Raut, Sanjoy Kumar Das

“…Functional and taxonomical analysis identified genes involved in carbon regulation, including Triacylglycerol lipase, NarG, DsrB, DNA-binding transcriptional dual regulator CRP, Vanillate O-demethylase oxygenase, succinate-CoA ligase, Tetrahydrofolate ligase, Carboxylase, Ribulose-1,5-bisphosphate carboxylase/oxygenase, Glycine hydroxymethyltransferase, MAG: urease, Endosymbiont of Oligobrachia haakonmosbiensis, Ribulose bisphosphate carboxylase, Aconitate hydratase AcnA, and nitrous oxide reductase, suggesting the metabolic versatility of these microbial communities for carbon cycling. …”
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Anti-inflammatory potential of black cumin seed oil and its nanoemulsion formulation against lipopolysaccharide-induced liver injury in mice by Hesham Haffez, Rehab Hosni, Shady A. Swidan, Hatem K. Amin

“…Hepatic inflammatory markers including Toll-like receptor 4 (TLR4), interleukin(IL)-1β, heme-oxygenase 1, BAX, and BCL-2 were assessed using real-time PCR. …”
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Microbial carbon oxidation in seawater below the hypoxic threshold by Sarah Wolf, Clare Jayawickrama, Craig A. Carlson, Curtis Deutsch, Edward W. Davis, Benjamin N. Daniels, Francis Chan, Stephen J. Giovannoni

“…Our findings support the hypothesis that oxygenase kinetics might slow the progression of ocean deoxygenation in oxygen-poor regions and be a factor in the evolution of microbial taxa adapted to hypoxic environments.…”
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Efficacy and Safety Concerns with Sn-Mesoporphyrin as an Adjunct Therapy in Neonatal Hyperbilirubinemia: A Literature Review by Prakar Poudel, Sudhir Adhikari

“…The rationale logic of heme oxygenase enzyme inhibition to lower bilirubin levels is intriguing. …”
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Fish Oil in the Treatment of Ulcerative Colitis by C Ó'Moráin, A Tobin, T McColl, Y Suzuki

“…Eicosapentaenoic acid (EPA) competitively inhibits the cyclo-oxgenase pathway and reduces the formation of cyclo-oxygenase pathway products. EPA is a good substrate for lipoxygenase enzymes and is efficiently converted to leukotriene 85, which is less biologically active. …”
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Salivary Biomarkers: Noninvasive Ways for Diagnosis of Parkinson’s Disease by Sanaz Salaramoli, Hamid Reza Joshaghani, Seyed Isaac Hashemy

“…Although salivary flow rate is decreased in PD patients, high levels of heme oxygenase and acetylcholinesterase might be used as noninvasive biomarkers. …”
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Significance of Persistent Inflammation in Respiratory Disorders Induced by Nanoparticles by Yasuo Morimoto, Hiroto Izumi, Etsushi Kuroda

“…In inhalation studies and instillation studies of nanomaterials, persistent inflammation is composed of neutrophils and alveolar macrophages, and its pathogenesis is related to chemokines such as the cytokine-induced neutrophil chemoattractant (CINC) family and macrophage inflammatory protein-1α and oxidant stress-related genes such as heme oxygenase-1 (HO-1). DNA damages occur chemically or physically by nanomaterials. …”
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Research Advances on Biosynthesis, Regulation, and Biological Activities of Apocarotenoid Aroma in Horticultural Plants by Jianan Shi, Chao Cao, Jiayu Xu, Chunhua Zhou

“…Apocarotenoids, which play important roles in the growth and development of horticultural plants, are produced by the action of carotenoid cleavage oxygenase (CCO) family members or nonenzymatic cleavage actions. …”
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Effect of Hemin on Brain Alterations and Neuroglobin Expression in Water Immersion Restraint Stressed Rats by Merhan Ragy, Fatma Ali, Maggie M. Ramzy

“…In the brain, the heme oxygenase (HO) system has been reported to be very active and its modulation seems to play a crucial role in the pathophysiology of neurodegenerative disorders. …”
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Comparative Neuroprotective Effects of Dexamethasone and Minocycline during Hepatic Encephalopathy by Maha Gamal, Zainab Abdel Wahab, Mohamed Eshra, Laila Rashed, Nivin Sharawy

“…Methods. 48 male albino rats were divided into 4 groups: control group, acute liver injury (ALI) group, minocycline pretreated ALI group, and dexamethasone pretreated ALI group. 24 hours after acute liver injury serum ammonia, liver enzymes, brain levels of heme oxygenase-1 gene, iNOS gene expression, nitrite/nitrate, and cytokines were measured. …”
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Nobiletin Decreases Inflammatory Mediator Expression in Tumor Necrosis Factor-Stimulated Human Periodontal Ligament Cells by Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki

“…Furthermore, nobiletin treatment enhanced nuclear factor, erythroid 2 like 2 (NFE2L2) and heme oxygenase 1 (HMOX1) expressions in TNF-stimulated HPDLCs. …”
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