Self-assembled biodegradable herbal-based nanoflower decorative magnesium implants combine therapy with bone regeneration by Huihui Du, Dongdong Zhang, Kui Xue, Limin Ma, Ru Xu, Ji Tan, Feng Peng, Xuanyong Liu

“…Moreover, Cur-Fe coating exhibits remarkable narrow gap semiconductor characteristics, which can generate reactive oxygen species (ROS) and demonstrated excellent antibacterial effect under simulated sunlight (SSL) irradiation. …”
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GsMTx-4 venom toxin antagonizes biophysical modulation of metastatic traits in human osteosarcoma cells by Arianna Buglione, Giulia Alloisio, Chiara Ciaccio, David Becerril Rodriguez, Simone Dogali, Marco Luce, Stefano Marini, Antonio Cricenti, Magda Gioia

“…To elucidate the molecular mechanisms that translate biomechanical alterations into biochemical responses, we employed Western blotting, real-time quantitative RT-PCR, reactive oxygen species ROS assay, and the mechanosensitive channel blocker Grammostola MechanoToxin4 (GsMTx-4). …”
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The discovery and characterization of K‐563, a novel inhibitor of the Keap1/Nrf2 pathway produced by Streptomyces sp by Ran Hori, Kozo Yamaguchi, Hidetaka Sato, Miwa Watanabe, Kyoko Tsutsumi, Susumu Iwamoto, Masayuki Abe, Hideyuki Onodera, Satoshi Nakamura, Ryuichiro Nakai

“…K‐563 suppressed the expression of Keap1/Nrf2 pathway downstream target genes or the downstream target protein, which induced suppression of GSH production, and activated reactive oxygen species production in A549 cells. K‐563 also inhibited the expression of downstream target genes in other Keap1‐ or Nrf2‐mutated cancer cells. …”
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Spin polarization induced by atomic strain of MBene promotes the ·O2 – production for groundwater disinfection by Zhaoli Liu, Wenzhe Gao, Lizhi Liu, Yixuan Gao, Cui Zhang, Long Chen, Fan Lv, Jiafeng Xi, Ting Du, Linpin Luo, Junchen Zhuo, Wentao Zhang, Yanwei Ji, Yizhong Shen, Wen Liu, Jianlong Wang, Mingchuan Luo, Shaojun Guo

“…However, the spin-forbidden feature of O2 hinders the photocatalytic generation of active ·O2 −, and thus greatly limited the disinfection efficiency, especially for real groundwater with a low dissolved oxygen (DO) concentration. Herein, we report a class of strained Mo4/3B2-xTz MBene (MB) with enhanced adsorption/activation of molecular O2 for photocatalytic disinfection, and find the strain induced spin polarization of In2S3/Mo4/3B2-xTz (IS/MB) can facilitate the spin-orbit hybridization of Mo sites and O2 to overcome the spin-forbidden of O2, which results in a 16.59-fold increase in ·O2 − photocatalytic production in low DO condition (2.46 mg L-1). …”
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Cultivatable Bacteriota of Chronic Wound of Patients with Diabetic Foot Syndrome with Critical Limb Ischemia Based on Wound Biopsy in Peri-Revascularization Period by Syedah Sarah Hussaini, Fran Dominic Grubesa, Mateusz Gajda, Martyna Schönborn, Katarzyna Bogucka, Mikołaj Maga, Paweł Maga, Jadwiga Wójkowska-Mach

“…The baseline parameters of the blood supply to the limb were Transcutaneous Oxygen Perfusion (TCPO2) of 15.0 mmHg, an Ankle Brachial Index (ABI) of 0.7, and a Toe Brachial Index (TBI) of 0.1, with an average Wound, Infection, Inflammation (WIfI) score of 5.7 (high). …”
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mtSTAT3 suppresses rheumatoid arthritis by regulating Th17 and synovial fibroblast inflammatory cell death with IL-17-mediated autophagy dysfunction by Seon-Yeong Lee, Jeonghyeon Moon, A Ram Lee, Young-Mee Moon, Jeong Won Choi, Chae Rim Lee, Su Been Jeon, Hee Su Sohn, Jeehee Youn, Dongyun Shin, Sung-Hwan Park, Mi-La Cho

“…In mouse and human immune cells, ZnSO4, an inducer of mitochondrial STAT3, decreases the production of reactive oxygen species, the IL-17 concentration, and differentiation into Th17 cells. …”
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NORDIC denoising on VASO data by Lasse Knudsen, Lasse Knudsen, Luca Vizioli, Federico De Martino, Lonike K. Faes, Daniel A. Handwerker, Steen Moeller, Peter A. Bandettini, Peter A. Bandettini, Laurentius Huber

“…Furthermore, laminar fMRI is challenged with signal displacements due to draining vein effects in conventional gradient-echo blood oxygen level-dependent (BOLD) imaging contrasts. fMRI contrasts such as cerebral blood volume (CBV)-sensitive vascular space occupancy (VASO) sequences have the potential to mitigate draining vein effects. …”
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The role of oxidized non-coding RNAs of the epigenome in the development of human diseases (literature review) by S.S. Ostrovska, Ye.N. Dychko, T.Ye. Shumna, G.I. Titov, O.S. Trushenko, P.G. Gerasymchuk, I.Y. Burega

“…Specific microRNAs and reactive oxygen species were identified as potential biomarkers in human malignancies, which expands the possibilities of their use as therapeutic targets. …”
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Transcranial vibration stimulation at 40 Hz induced neural activity and promoted the coupling of global brain activity and cerebrospinal fluid flow by Linghan Kong, Wei Jin, Yue Jiang, Fuhua Yan, Jun Liu, Eric C. Leuthardt, Guang-Zhong Yang, Yuan Feng

“…Additionally, this study investigates alterations in the global blood-oxygen-level-dependent (gBOLD) signal and cerebrospinal fluid (CSF) inflow coupling, which serve as indicators of glymphatic system function. …”
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Particle emission and thermal efficiency analysis of a diesel vehicle using biodiesel and a platinum metallic partial-flow particulate filter by Huy Quang Dang, Mi Zwe Mon Phyo, Poonnut Thaeviriyakul, Plan Teekatasn Cosh, Mek Srilomsak, Therdsak Petblengsri, Ittipol Pawarmart, Sompong Srimanosaowapak, Hidenori Kosaka, Preechar Karin

“…The results indicated that BSFC values increased with the biodiesel ratio in the blends, attributed to lower heating values. However, higher oxygen contents with increasing biodiesel ratios led to more complete combustion and improved brake thermal efficiency. …”
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Extracellular vimentin is a damage-associated molecular pattern protein serving as an agonist of TLR4 in human neutrophils by Łukasz Suprewicz, Krzysztof Fiedoruk, Karol Skłodowski, Evan Hutt, Magdalena Zakrzewska, Alicja Walewska, Piotr Deptuła, Agata Lesiak, Sławomir Okła, Peter A. Galie, Alison E. Patteson, Paul A. Janmey, Robert Bucki

“…CitVim stimulated the enhanced migratory ability of neutrophils, activation of NF-κB, and induction of NET formation mainly mediated through reactive oxygen species (ROS)-dependent and TLR4-dependent pathways. …”
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Effect of bromelain on ischemia-reperfusion injury in the torsion model created in polycystic and normal ovarian tissues by Sevgi Ulusoy Tangul, Taylan Onat, Demet Aydoğan Kirmizi, Zuleyha Doganyigit, Emin Kaymak, Aslı Oflamaz, Atilla Şenayli, Salih Somuncu

“…In treating ovarian torsion, detorsion is applied to ensure oxygenation of hypoxic tissues. However, the resulting oxygen radicals cause tissue damage. …”
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RNA m6A involves in regulation of oxidative stress and apoptosis may via NF-kB pathway in cadmium-induced lung cells by Nan Zhang, Jie Yang, Yuan Zhao, Wenhong Li, Bo Zhao, Rongxian Li, Zuoshun He, Shiyan Gu

“…Proteomic assay revealed that in passage 40 cells, 350 proteins showed differentially expressed in comparison to control, and these proteins were primarily enriched in Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways of “pathways in cancer” and “Chemical carcinoma-reactive oxygen species”. Moreover, the mRNAs of Nuclear factor kappa B (NF-κB) p65 and NAD(P)H: quinone oxidoreductase 1 (NQO1), the key signaling molecules in these two signaling pathways, were predicted to contain m6A modification sites with high confidence. …”
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Design, Synthesis, and Antioxidant and Anti-Tyrosinase Activities of (<i>Z</i>)-5-Benzylidene-2-(naphthalen-1-ylamino)thiazol-4(5<i>H</i>)-one Analogs: In Vitro and In Vivo Insight... by Hee Jin Jung, Hye Jin Kim, Hyeon Seo Park, Hye Soo Park, Jeongin Ko, Dahye Yoon, Yujin Park, Pusoon Chun, Hae Young Chung, Hyung Ryong Moon

“…Compounds <b>8</b> and <b>10</b> exhibited strong antioxidant capacities, scavenging 2,2-diphenyl-1-picrylhydrazyl, (2,2-azino-bis-3-ethylbenzothiazoline-6-sulphonic acid)⁺ radicals, and reactive oxygen species. Hybrid compounds <b>10</b> and <b>15</b> are potential therapeutic agents for skin hyperpigmentation disorders.…”
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Polydatin enhances oxaliplatin-induced cell death by activating NOX5-ROS-mediated DNA damage and ER stress in colon cancer cells by Qi Zhao, Qi Zhao, Qi Zhao, Yan Zhang, Yan Zhang, Jieyu Liu, Peipei Chen, Annabeth Onga, Namki Cho, Ri Cui, Chenguo Zheng

“…Consequently, the search for anti-cancer components with high efficacy and low cytotoxicity has become a significant focus in recent years.MethodsThe anti-tumor effects of PD, OXA or their combination were assessed by cell viability, colony formation, and wound-healing assays. Reactive oxygen species (ROS) generation was measured by flow cytometry and DNA damage was assessed by immunofluorescence assay. …”
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Laboratory-scale biogas production from vegetable juice waste using an IC reactor by Boualy Vongvisith, Chengyue Liang, Changmei Wang, Fang Yin, Kai Wu, Bin Yang, Jing Liu, Hong Yang, Wudi Zhang

“…The efficiency of the IC reactor was reflected in the effluent chemical oxygen demand (COD) concentration reduction and the percentage of COD removal efficiency. …”
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A sedimentological oxymoron: highly evolved glauconite of earliest diagenetic origin by Tribovillard, Nicolas, Bout-Roumazeilles, Viviane, Guillot, François, Baudin, François, Deconinck, Jean-François, Abraham, Romain, Ventalon, Sandra

“…The carbonate beds yield field evidences of an early diagenetic origin and both beds and interbeds contain glauconite, questioning the duration of formation of the glauconite, relative to that of the diagenetic carbonate beds. Carbon and oxygen stable isotope composition of the carbonate beds confirm an early diagenetic growth. …”
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Association of C1q/TNF-Related Protein-9 (CTRP9) Level with Obstructive Sleep Apnea in Patients with Coronary Artery Disease by Zexuan Li, Yunhui Du, Lixin Jia, Jingyao Fan, Ruifeng Guo, Xinliang Ma, Xiao Wang, Shaoping Nie, Yongxiang Wei

“…Correlation analysis showed that CTRP9 levels were negatively correlated with AHI (r=−0.238, P=0.003) and oxygen desaturation index (r=−0.234, P=0.004) and positively correlated with left ventricular ejection fraction (r=0.251, P=0.004) in all subjects. …”
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Physiological arterial pressure improves renal performance during normothermic machine perfusion in a porcine kidney DCD model by Yitian Fang, Gisela Ambagtsheer, Lin Xia, Marian C. Clahsen-van Groningen, Robert C. Minnee, Ron W.F. de Bruin

“…The 115 mmHg group exhibited significantly higher oxygen consumption compared to the 75 mmHg group at 30 min of NMP [1.37 (1.05–1.92) versus 0.72 (0.61–0.82) mlO2/min/100g, p = 0.009]. …”
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Assessments of prostate cancer cell functions highlight differences between a pan‐PI3K/mTOR inhibitor, gedatolisib, and single‐node inhibitors of the PI3K/AKT/mTOR pathway by Adrish Sen, Salmaan Khan, Stefano Rossetti, Aaron Broege, Ian MacNeil, Ann DeLaForest, Jhomary Molden, Laura Davis, Charles Iversrud, Megan Seibel, Ross Kopher, Stephen Schulz, Lance Laing

“…The superior effects of gedatolisib were likely associated with more effective inhibition of critical PAM‐controlled cell functions, including cell cycle, survival, protein synthesis, oxygen consumption rate, and glycolysis. Our results indicate that potent and simultaneous blockade of all class I PI3K isoforms, mTORC1, and mTORC2 could circumvent PTEN‐dependent resistance. …”
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