TAK-242 improves sepsis-associated acute kidney injury in rats by inhibiting the TLR4/NF-κB signaling pathway by Yan-mei Xia, Yu-qian Guan, Ji-fang Liang, Wei-dong Wu

“…Finally, the expression of proteins related to the TLR4/NF-κB signaling pathway was observed by western blot.Results Compared with the CLP + vehicle and CLP + TAK-242 groups, the CLP + TAK-242 group reduced blood urea nitrogen (BUN), creatinine (Cr), cystatin-C (Cys-C), reactive oxygen species (ROS), malondialdehyde (MDA), and inflammatory factors levels (p < 0.01), as well as increased superoxide dismutase (SOD) activity of CLP rats (p < 0.01). …”
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Your brain on art, nature, and meditation: a pilot neuroimaging study by Beatrix Krause-Sorio, Sergio Becerra, Prabha Siddarth, Stacey Simmons, Taylor Kuhn, Helen Lavretsky

“…The blocks included (1) nature videos, (2) AI-generated digital art (“machine hallucinations” by Refik Anadol), and (3) videos of NASA Webb-produced images of galactic nebulas. Brain oxygen-level dependent (BOLD) images were processed using FSL Version 6.0 and a general linear model (GLM) tested the contrasts between art, nature, and meditation blocks, using a cluster-corrected p-value of 0.05.ResultsCompared to rest, meditation led to BOLD increases in bilateral lateral occipital and fusiform gyri, as well as right postcentral gyrus and hippocampus. …”
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Protective Effects of Chitosan Oligosaccharide Against Lipopolysaccharide-Induced Inflammatory Response and Oxidative Stress in Bovine Mammary Epithelial Cells by Ziwei Lin, Yanlong Zhou, Ruiwen Chen, Qiuyan Tao, Qiwen Lu, Qianchao Xu, Haibin Yu, Ping Jiang, Zhihui Zhao

“…COS treatment also suppressed excessive reactive oxygen species (ROS) production and restored antioxidant enzyme activity under LPS-induced oxidative stress conditions. …”
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Effect of Xingnao Kaiqiao Acupuncture combined with EEG Biomimetic Electrical Stimulation on Evoked Potential of Patients with Persistent Vegetative State by Lixia DENG, Jiquan LIU, Liangxiang ZHANG, Xiao LV, Xing CHEN, Yigang FENG, Yingying NI

“…All groups were given routine treatment, including basic management, hyperbaric oxygen therapy and drug treatment etc. In addition, the Acupuncture group received Xingnao Kaiqiao acupuncture, the refreshement treatment, at which the main acupoints were Shuigou, bilateral Neiguan, bilateral Sanyinjiao, and the auxiliary acupoints were Jiquan, Chize and Weizhong acupoints, once a day, the Bionic electricity group received the treatment of EEG bionic electrical stimulation, the main electrode were placed at GB 12 and BL 10, each treatment was for a continuous 99 min followed by a rest of 30 min, followed by another 99 min, once a day, the Combined group received Xingnao Kaiqiao acupuncture combined with EEG bionic electrical stimulation, once a day. …”
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Nursing Skill Assessment of Hospital Nurses in Management of Critically Ill Patients by Lingli Xu, Qiyu Sun, Jiayi Feng, Li Jing Huang, Chunjing Xu, Weihong Shen, Jian Ding, Yongmei Jin

“…The rescue time of cardiopulmonary resuscitation, oxygen inhalation, venous opening, and endotracheal resuscitation in the observation group was 3.24±1.01, which is lower than that in the control group, 6.65±2.11, with statistical significance (P<0.05). …”
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Lead toxicity in Nicotiana tabacum L.: Damage antioxidant system and disturb plant metabolism by Tengfei Liu, Kai Zhang, Chunlan Ming, Jiashu Tian, Huanyu Teng, Zicheng Xu, Jiewang He, Fengfeng Liu, Yinghui Zhou, Jiayang Xu, Mohamed G. Moussa, Shenghua Zhang, Wei Jia

“…These results indicate that increasing the content of photosynthetic pigments and hormones, clearing reactive oxygen species by enhancing antioxidant enzyme activity, and improving amino acid metabolism may play an important role in reducing the toxicity of Pb to tobacco.…”
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Sulfated Cyclocarya paliurus polysaccharides exert immunomodulatory potential on macrophages via Toll-like receptor 4 mediated MAPK/NF-κB signaling pathways by Yue Yu, Haibin Zhu, Mingyue Shen, Qiang Yu, Yi Chen, Shiru Mo, Jianhua Xie

“…Meanwhile, SCP3 could activate mitogen-activated protein kinase (MAPK) and nuclear factor kappa B (NF-κB) signaling pathways, which increased the phosphorylation of Erk1/2, JNK, p38 and NF-κB p65, promoting secretion of cytokines tumor necrosis factor α (TNF-α), interleukin 6 (IL-6) and nitric oxide (NO) as well as the production of reactive oxygen species (ROS). In addition, Toll-like receptor 4 (TLR4) receptor inhibitors were able to block the production of NO and TNF-α by SCP3-stimulated macrophages. …”
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An ATP-activated spatiotemporally controlled hydrogel prodrug system for treating multidrug-resistant bacteria-infected pressure ulcers by Xiaoliang Qi, Yajing Xiang, Ying Li, Jiajia Wang, Yuxi Chen, Yulong Lan, Jinsong Liu, Jianliang Shen

“…Subsequently, the bacteria-secreted ATP prompts the degradation of IZPP, allowing the loaded IAA prodrug and nanozyme to encounter spatiotemporally on a single carrier, thereby efficiently generating reactive oxygen species (ROS). Exposure to 808 nm near-infrared light enhances the catalytic reaction speed, boosting ROS levels for stronger antibacterial action. …”
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Efficacy, efficiency and safety of a cardiac telerehabilitation programme using wearable sensors in patients with coronary heart disease: the TELEWEAR-CR study protocol by Andrew Xanthopoulos, Eleni Kapreli, Garyfallia Pepera, Konstantinos I Gourgoulianis, Varsamo Antoniou, Gregory Giamouzis, Constantinos Davos, Ladislav Batalik, Vasileios Stavrou, John Skoularigis

“…The primary outcomes will be the assessment of cardiorespiratory fitness, expressed as peak oxygen uptake assessed by the CPET test and the 6 min walk test. …”
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Anti-Inflammatory and Prebiotic Potential of Ethanol Extracts and Mucilage Polysaccharides from Korean Yams (<i>Dioscorea polystachya</i> and <i>Dioscorea bulbifera</i>) by So-Yoon Park, Van-Long Truong, Su-Gyeong Jeon, So-Young Choe, Razanamanana H. G. Rarison, Byoung-Hoon Yoon, Ji-Won Park, Hye-Jeong Jeong, Woo-Sik Jeong

“…Among the extracts, the 95% ethanol extract exhibited the most potent inhibition of reactive oxygen species (ROS) and nitric oxide (NO) production, warranting further exploration of its mechanisms of action. …”
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Comparison of Nasopharyngeal Airway with Endoscopic Respiratory Mask for Hypoxemia in Painless Gastrointestinal Endoscopy in Obese Outpatients: Study Protocol for a Randomized Cont... by Xiang D, Deng L, Zhou R, Zhang X, Tian L, Jiang W, Zhou Y, Chen W, Peng Y

“…Patients in group N will undergo intubation of the nasopharyngeal airway prior to examination, whereas patients in group C will receive oxygen therapy through an endoscopic respiratory mask at a flow rate of 10 L/min during the procedure. …”
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Aminoguanidine hemisulfate improves mitochondrial autophagy, oxidative stress, and muscle force in Duchenne muscular dystrophy via the AKT/FOXO1 pathway in mdx mice by Shiyue Sun, Tongtong Yu, Joo Young Huh, Yujie Cai, Somy Yoon, Hafiz Muhammad Ahmad Javaid

“…This study investigates the effects of aminoguanidine hemisulfate (AGH), an inhibitor of reactive oxygen species (ROS), on mitochondrial autophagy, oxidative stress, and muscle force in mdx mice. …”
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Moxibustion Regulates the BRG1/Nrf2/HO-1 Pathway by Inhibiting MicroRNA-222-3p to Prevent Oxidative Stress in Intestinal Epithelial Cells in Ulcerative Colitis and Colitis-Associat... by Xuejun Wang, Haiyang Ji, Yanting Yang, Dan Zhang, Xiehe Kong, Xiaoying Li, Hongna Li, Yunqiong Lu, Guang Yang, Jie Liu, Huangan Wu, Jue Hong, Xiaopeng Ma

“…With changes in reactive oxygen species (ROS), malondialdehyde (MDA), glutathione peroxidase (GSH-Px), and inflammatory cytokines interleukin (IL)-1β and tumor necrosis factor (TNF)-α), we verified that HPM protects against oxidative stress and inflammation in IECs of UC and CAC mice. …”
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Distinct phenotypes of patients and healthcare resource utilization after hospitalization for COVID-19: an observational study by Claire Marant Micallef, Manon Belhassen, Florence Ader, Valeria Martinez, Eric Van Ganse, Marjorie Bérard, Mélanie Née, Mikhail Dziadzko, Frédéric Aubrun

“…We described the sociodemographic and clinical characteristics of the participants and 44 selected types of HCU, including medical and emergency room visits, medications, medical and biological tests, oxygen therapy, rehabilitation, rehospitalization, nurse visits, and sick leave. …”
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Irisin Attenuates Hepatic Stellate Cell Activation and Liver Fibrosis in Bile Duct Ligation Mice Model and Improves Mitochondrial Dysfunction by Thuy Linh Lai, So Young Park, Giang Nguyen, Phuc Thi Minh Pham, Seon Mee Kang, Jeana Hong, Jae-Ho Lee, Seung-Soon Im, Dae-Hee Choi, Eun-Hee Cho

“…Results In vitro, irisin mitigated HSC activation and reduced reactive oxygen species associated with the TGF-β1/Smad signaling pathway. …”
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The extensive cultivation of Pyropia haitanensis along the coastal areas influences the ecological dynamics of nearby intertidal mudflat pond water by Peihao Liu, Qijun Luo, Shanshan Zhu, Juanjuan Chen, Rui Yang, Tingting Niu, Tiegan Wang, Peng Zhang, Haimin Chen

“…The dynamic diversity patterns and structure of microbial communities were determined by 16S and 18S rRNA sequencing, and the environmental factors were measured.ResultsIn the offshore aquaculture area, the cultivation of P. haitanensis increased the dissolved oxygen and pH, decreased inorganic nutrients, reduced the alpha diversity of bacteria, established the dominance of Proteobacteria, but did not influence the composition of microeukaryotes. …”
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The effect of electroslag remelting on the cleanliness of CrNiMoWMnV ultrahigh-strength steels by Ali M., Porter D., Kömi J., Heikkinen E.P., Eissa M., El Faramawy H., Mattar T.

“…Al2O3 inclusions were formed as a result of the addition of Al as a deoxidant to the ESR slag to prevent penetration of oxygen to the molten steel.…”
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Lutein and inflammation: a comprehensive review of its mechanisms of action by Paradentavida Prathyusha, Geetha Viswanathan, Anjilikal Tomy Tomcy, Ponnamparambil P. Binitha, Smitha V. Bava, Edakkadath R. Sindhu

“…Due to its anti-oxidative and singlet oxygen quenching properties, lutein is reported to reduce the risk of age-related macular degeneration (AMD). …”
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Correlation between ellipsoid zone thickness and the presence of subretinal drusenoid deposits in age-related macular degeneration by Richard B Rosen, Roland Theodore Smith, Gerardo Ledesma-Gil, Oscar Otero-Marquez, Yuehong Tong, Katy Tai, Gareth M C Lema, Raymond Matthew Bellis, Yang Fei, Brandon Le

“…This thinning gradation is consistent with progressive destruction of highly oxygen-sensitive mitochondria in the EZ from hypoxia. …”
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Collection of microorganisms of ICG SB RAS as a genetic resource for biotechnology by A. V. Bryanskaya, Y. E. Uvarova, A. S. Rozanov, N. M. Slynko, V. N. Shlyakhtun, K. V. Starostin, E. A. Demidov, E. V. Lazareva, O. P. Taran, S. E. Peltek

“…The physiological characteristics of the strains of the collection have been established: the attitude to oxygen, the type of nutrition, the range of temperature and pH, the attitude to NaCl and others. …”
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