-
3761
Effect of Co-Administration of Midazolam and Dexmedetomidine on Haemodynamics and Stress Response in Elderly Patients with Non-Small Cell Lung Cancer
Published 2025-12-01“…Patients treated with dexmedetomidine plus midazolam presented with a more stable hemodynamic status than those treated with dexmedetomidine only, as evidenced by the significantly lower variability of mean arterial pressure (MAP), oxygen saturation (SpO2), and heart rate (HR). Co-administration of dexmedetomidine plus midazolam for lobectomy anesthesia resulted in significantly lower serum cortisol (Cor) and norepinephrine (NE) concentrations in patients at anesthesia recovery than dexmedetomidine alone. …”
Get full text
Article -
3762
Next-generation calcium oxide nanoparticles: A breakthrough in energy storage and humidity sensing
Published 2025-03-01“…XPS analysis confirmed that the sample was mainly composed of calcium [25.34 %], and oxygen [63.53 %]. TGA showed two significant weight losses, the former 9.81 % at 390–420 °C due to thermal decomposition of calcium hydroxide to calcium oxide and water and the later 18.98 % at 600–700 °C due to removal of chemical adsorbed water molecules and disintegration of the left over CaCO3. …”
Get full text
Article -
3763
g-C3N4 nanosheets coupled with CoSe2 as co-catalyst for efficient photooxidation of xylose to xylonic acid
Published 2025-01-01“…Herein, this study reveals the unique function of CoSe2, which can significantly promote oxygen adsorption, work as an electron sink and accelerate the generation of ·O2−, thereby improving the selectivity toward xylonic acid over other by-products. …”
Get full text
Article -
3764
Dexmedetomidine pretreatment enhances protective effect efficacy of pericytes agaist acute lung injury in septic mice
Published 2025-01-01“…After PCs and Dex-PCs were exposed to 10 μg/mL LPS, the level of intracellular reactive oxygen species (ROS) was measured. Results Compared with the Sham group, the ALI group had increased permeability of pulmonary vascular endothelial cells, extensive extravasation of Evans blue, severely destructed of lung tissue structure and massive inflammatory cell infiltration, higher lung wet/dry weight ratio, elevated serum TNF-α and IL-6 levels, and declined lung function, and no mice survived for 72 h after modeling (P<0.05). …”
Get full text
Article -
3765
The Effect of Lithium on Inflammation-Associated Genes in Lipopolysaccharide-Activated Raw 264.7 Macrophages
Published 2020-01-01“…A reduced internal H2DCFDA fluorescence intensity, indicative of reduced reactive oxygen species (ROS) production, was observed in LPS-activated Raw 264.7 macrophages treated with lithium. …”
Get full text
Article -
3766
De novo assembly and analysis of the transcriptome of the Siberian wood frog Rana amurensis
Published 2022-03-01“…It can survive for several months in an almost complete absence of oxygen. Little is known about the mechanisms of this remarkable resilience, in part because studies of amphibian genomes are impeded by their large size. …”
Get full text
Article -
3767
The interplay of ferroptosis and oxidative stress in the pathogenesis of aortic dissection
Published 2025-02-01“…Ferroptosis, a form of iron-dependent programmed cell death, occurs alongside lipid peroxidation and the accumulation of reactive oxygen species (ROS). The relationship between ferroptosis and AD lies in its damaging effect on vascular cells. …”
Get full text
Article -
3768
Over-Expression of MicroRNA-210 and MicroRNA-185-5p in Normotensive Late-Fetal Growth Restriction: Preliminary Cohort Study
Published 2024-08-01“… OBJECTIVE: Late Fetal Growth Restriction (LFGR), a condition associated with perinatal and long-term neurodevelopmental problems, is caused by inadequate placental transfer of oxygen and nutrients to the fetus. This preliminary study evaluates the expression profiles and clinical significance of hypoxia-sensitive microRNA-210 (miR-210) and microRNA-185-5p (miR-185-5p) in placental and maternal circulation. …”
Get full text
Article -
3769
Synergistic anti-oxidative/anti-inflammatory treatment for acute lung injury with selenium based chlorogenic acid nanoparticles through modulating Mapk8ip1/MAPK and Itga2b/PI3k-AKT...
Published 2025-01-01“…The CHSe NPs exhibited superoxide dismutase(SOD) like and glutathione peroxidase(GPX) like activities, effectively scavenging various types of reactive oxygen species (ROS), and inhibited the inflammatory response of macrophages. …”
Get full text
Article -
3770
Annealing temperature modify of crystalline structure, magnetic properties and antibacterial performance in nickel substituted cobalt ferrite nanoparticles utilizing natural-fine-s...
Published 2024-12-01“…Meanwhile, FTIR results showed the presence of metal-oxygen bonds at 551-586 cm-1 and 384-391 cm-1 at tetrahedral (k1) and the octahedral (k2) sites for both NiCFO-fs and NiCFO-pa nanoparticles samples. …”
Get full text
Article -
3771
Alterations in Adipose Tissue and Adipokines in Heterozygous APE1/Ref-1 Deficient Mice
Published 2024-12-01“…Oxidative stress was assessed by evaluating reactive oxygen species (ROS) levels. Histological and immunohistochemical analyses were conducted to observe adipocyte size and macrophage infiltration of WAT. …”
Get full text
Article -
3772
Ethanolic extract of Dayak onion (Eleutherine palmifolia) prevented sperm membran damage in mice exposed to monosodium glutamate
Published 2024-11-01“…Monosodium glutamate (MSG) could cause increased production of reactive oxygen species (ROS), causing oxidative stress in the testicles, which adversely affected sperm quality. …”
Get full text
Article -
3773
Investigating the antioxidant and anti-inflammatory potential of Nypa fruticans: a multifaceted approach to skin protection and aging
Published 2025-01-01“…Abstract Reactive oxygen species (ROS) produced in the mitochondria of skin cells play a significant role in the degradation of the extracellular matrix and induction of inflammatory responses, both of which are major contributors to skin aging. …”
Get full text
Article -
3774
Advances in the treatment of glioma-related signaling pathways and mechanisms by metformin
Published 2025-01-01“…Metformin’s inhibition of glioma proliferation involves complex cellular processes, including mitochondrial dysfunction, increased reactive oxygen species (ROS) production, and modulation of immune responses. …”
Get full text
Article -
3775
Resveratrol Alleviates NEFA-Induced Oxidative Damage in Bovine Mammary Epithelial Cells by Restoring Mitochondrial Function
Published 2025-01-01“…The results showed that RES ameliorated NEFA-induced oxidative damage by upregulating antioxidant enzyme expression and reducing malondialdehyde (MDA) and reactive oxygen species (ROS). Furthermore, exogenous NEFAs resulted in a decrease in mitochondrial membrane potential (MMP), cellular adenosine triphosphate (ATP) production, energy metabolism (NAD<sup>+</sup>/NADH ratio), abnormal mitochondrial structure and an increase in apoptosis levels. …”
Get full text
Article -
3776
Verbascoside Inhibits the Activation of NLRP3 Inflammasome and Improves BV-2 Cell Inflammatory Damage
Published 2025-02-01“…Methods: A model of inflammatory damage induced by oxygen-glucose deprivation (OGD) in BV-2 cells was employed. …”
Get full text
Article -
3777
Gallic acid alleviates exercise-induced muscle damage by inhibiting mitochondrial oxidative stress and ferroptosis
Published 2025-01-01“…JC-1, DHE, and C11-BODIPY 581/591 probes were used to detect mitochondrial membrane potential, mitochondrial reactive oxygen species (mtROS), and lipid peroxidation levels. …”
Get full text
Article -
3778
Eco-Friendly Synthesis of Zirconium Dioxide Nanoparticles from <i>Toddalia asiatica</i>: Applications in Dye Degradation, Antioxidant and Antibacterial Activity
Published 2025-01-01“….% zirconium (Zr) and 62.82 mol.% oxygen. The ZrO<sub>2</sub> NPs demonstrated remarkable photocatalytic activity, degrading over 95% of methylene blue dye after 3 h of sunlight exposure. …”
Get full text
Article -
3779
Protective effect of brain and muscle arnt-like protein-1 against ethanol-induced ferroptosis by activating Nrf2 in mice liver and HepG2 cells
Published 2023-11-01“…Upon exposure to alcohol (5 % Lieber-DeCarli liquid alcohol diet for 10 days before binged alcohol with 5 g/kg body weight in vivo, 300 mmol/L for 12 h in vitro, respectively), the content of iron, reactive oxygen species (ROS) and malondialdehyde (MDA) was boosted significantly while glutathione (GSH) was decreased that mainly based on the downregulated protein expression of ferritin heavy chain (FTH), ferroportin (FPN), heme oxygenase1(HO-1) and anti-cystine/glutamate antiporter (SLC7A11), while these changes could be abolished by ferroptosis inhibitor Ferrostatin-1[Fer-1 (5 mg/kg body weight for 10 days in vivo, 10 μmol/L for 2 h in vitro, respectively)]. …”
Get full text
Article -
3780
Association Study between Novel CYP26 Polymorphisms and the Risk of Betel Quid-Related Malignant Oral Disorders
Published 2015-01-01“…BQ chewing may produce significant amounts of reactive oxygen species (ROS), resulting in oral mucosa damage, and ROS may be metabolized by CYP26 families. …”
Get full text
Article