A Novel Therapeutic Calcium Peroxide Loaded Injectable Bio-adhesive Hydrogel Against Periodontitis by Shaojie Dong, Yukun Mei, Yuwei Zhang, Wenqing Bu, Yifei Zhang, Changjie Sun, Rui Zou, Lin Niu

“…Materials and Methods: Gelatin-oxidized dextran hydrogel loaded with calcium peroxide and penicillin (CP-P hydrogel) was synthesized and characterized using Universal mechanical testing machine, Fourier transform infrared spectroscopy, swelling test, and dissolved oxygen meter. Furthermore, the cytotoxicity, osteogenic ability, antibacterial behavior, and alveolar bone regenerating capability of CP-P hydrogel were conducted both in vitro and in vivo. …”
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Genetic characterization of a rare case of pheochromocytoma in a pulmonary transplant patient by Stéfanie Parisien-La Salle, Florence Perreault, Gilles Corbeil, Julie Morisset, Charles Poirier, Catherine Beauregard, Agnès Räkel, Marjorie Labrecque, Martine Tétreault, Martine Tétreault, Christian Cohade, Pasquale Ferraro, Isabelle Bourdeau

“…Chronic hypoxia can lead to gain of function somatic variants in the EPAS1 gene that encodes for hypoxia-inducible factor 2-alpha (HIF-2α), involved in PPGL tumorigenesis.ObjectiveTo describe a rare case of PCC in a pulmonary transplant patient and characterize the tumour’s genetic background.Clinical CaseA 47 year-old man underwent a lung transplant for chronic obstructive pulmonary disease associated with alpha-1 antitrypsin deficiency. He required home oxygen therapy for 3 years prior to transplant. Nineteen years after transplant, a CT-scan revealed a 5.8 cm x 3.9 cm heterogeneous right adrenal mass (HU of 7). …”
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Comparison of search and rescue operations involving emergency physicians in devastating earthquakes in Turkey: a 24-year experience study by Mustafa Ferudun Celikmen, Gülbin Aydoğdu Umaç, Melih Imamoglu, Mümin Murat Yazici, Elif Çiğdem Keleş, Sarper Yilmaz

“…The most common interventions provided to the injured were intravenous fluid therapy (63.8%, n =102) and oxygen support (57.5%, n =92). The rate of intubation at the scene was 16.1% (n = 19) in the Marmara group and 4.8% (n = 2) in the Maraş group (p < 0.05). …”
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Investigation the effect of calcination heating rate on the structural, morphological, thermal and color properties of nano Cobalt Aluminate (CoAl2O4) by Md. Farid Ahmed, Monmon Podder, Md. Rassel Moni, Md. Lutfor Rahman, Bristy Biswas, Juliya Khanam, Mahmuda Hakim, Moksodur Rahman, Md. Sahadat Hossain, Nahid Sharmin

“…Energy Dispersive X-ray (EDX) Spectroscopy confirmed the purity of the composition, comprising cobalt, aluminum, and oxygen without any impurities. UV–visible spectrophotometry unraveled intriguing color changes associated with differing heating rates. …”
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Hydrothermal synthesis of a nickel-oxide-infused orange peel nanobiocomposite for enhanced heavy metal removal from mining wastewater by Jacques Romain Njimou, Velma Fai, Mary Tamwa Sieugaing, Djimongbaye Nguenamadje, John Godwin, Oben Bessem Genola, Guy Bertrand Noumi, Bankim Chandra Tripathy

“…The adsorption mechanism involves a two-step process where positively charged Cd2⁺ and Pb2⁺ ions diffuse toward the negatively charged surface of the Alg-OP-Ni nanobiocomposite and subsequently fix through interactions with surface oxygen atoms. Maximum adsorption capacities for Cd2⁺ and Pb2⁺ were determined to be 138.25 and 276.00 mg/g in single-component systems, and 224.00 and 317.10 mg/g in binary systems, respectively. …”
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Hsp70/Bmi1-FoxO1-SOD Signaling Pathway Contributes to the Protective Effect of Sound Conditioning against Acute Acoustic Trauma in a Rat Model by Guoxia Zhu, Yongxiang Wu, Yang Qiu, Keyong Tian, Wenjuan Mi, Xinqin Liu, Yuanyuan Chen, Jinwen Jia, Jiasheng Luo, Lianjun Lu, Jianhua Qiu

“…Further, we investigated the potential role of Hsp70 and Bmi1 in SC by targeting SOD1 and SOD2 which are regulated by the FoxO1 signaling pathway based on mitochondrial function and reactive oxygen species (ROS) levels. Finally, we sought to identify the possible molecular mechanisms associated with the beneficial effects of SC against noise-induced trauma. …”
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Nutritive Parameters and Antioxidant Quality of Minimally Processed "Cime di Rapa" ( Brassica rapa subsp. sylvestris ) Vary as Influenced by Genotype and Storage Time by Donato Giannino, Giulio Testone, Chiara Nicolodi, Lucia Giorgetti, Lorenza Bellani, Maria Gonnella, Marco Ciardi, Paolo Cappuccio, Stefano Moscatello, Alberto Battistelli, Vincenzo Longo

“…Contents of DF and GC (39.64-34.57; 7.56-2.21 g/100 g), glucosinolates (37.47-24.63 mg/g SIN), and ACC (total phenolics: 18.64-14.92 mg GAE/g; flavonoids: 34.74-30.96 mg/g CE; flavonols: 14.62-14.08 mg QE/g), and AOC (Oxygen Radical Absorbance Capacity: 354.62-293.25 µmol/g TE; DPPH• scavenging activity: 59.35-46.14) were lower in shoots of the hybrid than marketed cultivar. …”
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Multiple action sites of ultrasound on Escherichia coli and Staphylococcus aureus by Xinyu Liao, Jiao Li, Yuanjie Suo, Shiguo Chen, Xingqian Ye, Donghong Liu, Tian Ding

“…Keywords: Ultrasound, Inactivation mechanism, Reactive oxygen species (ROS), Staphylococcus aureus, Escherichia coli…”
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ROS-induced cytosolic release of mitochondrial PGAM5 promotes colorectal cancer progression by interacting with MST3 by Shiyang Wang, Xi Wu, Wenxin Bi, Jiuzhi Xu, Liyuan Hou, Guilin Li, Yuwei Pan, Hanfu Zhang, Mengzhen Li, Sujuan Du, Mingxin Zhang, Di Liu, Shuiling Jin, Xiaojing Shi, Yuhua Tian, Jianwei Shuai, Maksim V. Plikus, Moshi Song, Zhaocai Zhou, Lu Yu, Cong Lv, Zhengquan Yu

“…Abstract Aberrant release of mitochondrial reactive oxygen species (mtROS) in response to cellular stress is well known for promoting cancer progression. …”
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Use High-Flow Nasal Cannula for Acute Respiratory Failure Patients in the Emergency Department: A Meta-Analysis Study by Cheng-Chieh Huang, Hao-Min Lan, Chao-Jui Li, Tsung-Han Lee, Wen-Liang Chen, Wei-Yuan Lei, Pei-You Hsieh, Mei-Chueh Yang, Chu-Chung Chou, Han-Ping Wu, Yuan-Jhen Syue

“…To evaluate the efficacy of high-flow nasal cannula (HFNC) therapy compared with conventional oxygen therapy (COT) or noninvasive ventilation (NIV) for the treatment of acute respiratory failure (ARF) in emergency departments (EDs). …”
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Laboratory Rotational Spectroscopy Leads to the First Interstellar Detection of Singly Deuterated Methyl Mercaptan (CH2DSH) by Hayley A. Bunn, Silvia Spezzano, Laurent H. Coudert, Jean-Claude Guillemin, Yuxin Lin, Christian P. Endres, Brant Billinghurst, Olivier Pirali, Jes Jørgensen, Valerio Lattanzi, Paola Caselli

“…The column density ratio for HDCS/CH _2 DSH compared to HDCO/CH _2 DOH suggests a difference in the interstellar chemistry between the sulfur and oxygen complex organics, in particular a different link between H _2 CO and CH _3 OH and between H _2 CS and CH _3 SH. …”
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Long-term hypoxic atmosphere enhances the stemness, immunoregulatory functions, and therapeutic application of human umbilical cord mesenchymal stem cells by Qi-Ming Huang, You-Qiong Zhuo, Zhong-Xin Duan, Yin-lin Long, Jia-Nan Wang, Zhou-hang Zhang, Shao-Yong Fan, Yong-Ming Huang, Ke-Yu Deng, Hong-Bo Xin

“…Aims: Mesenchymal stem cells (MSCs) are usually cultured in a normoxic atmosphere (21%) in vitro, while the oxygen concentrations in human tissues and organs are 1% to 10% when the cells are transplanted in vivo. …”
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The ameliorative effects of melatonin against BDE-47-induced hippocampal neuronal ferroptosis and cognitive dysfunction through Nrf2-Chaperone-mediated autophagy of ACSL4 degradati... by Quan Yuan, Mingwei Wang, Zhaoxiang Zhang, Ruofei Wang, Dechao Wang, Zichun Sang, Pu Zhao, Xiaoli Liu, Xiaoying Zhu, Gaofeng Liang, Hua Fan, Dongmei Wang

“…Acyl-CoA synthetase long-chain family member 4 (ACSL4), a key lipid metabolism enzyme dictating ferroptosis sensitivity, accompanied by higher MDA and lipid reactive oxygen species (ROS), was remarkably increased under BDE-47 stress, while melatonin supplementation could suppress the elevated ACSL4 in vivo and in vitro. …”
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Impact of Cordyceps sinensis on coronary computed tomography angiography image quality and renal function in a beagle model of renal impairment by Peiji Song, Peiji Song, Kun Li, Xiaodie Xu, Guifeng Zhang, Zengkun Wang, Linbing Sun, Zekai Zhao, Ting Li, Ximing Wang, Zhangyong Xia, Zhangyong Xia, Zhangyong Xia, Zhangyong Xia

“…Renal function was assessed using MRI before and after the intervention, with IVIM (Intravoxel Incoherent Motion) and BOLD (Blood Oxygen Level Dependent) imaging of the kidneys. Key parameters, including the pure diffusion coefficient (D), pseudo-diffusion coefficient (D*), perfusion fraction (f), and R2*values, were quantified. …”
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The Use of Zeolit and Activated Carbon on Packing System of Corydoras aenus by E. Supriyono, E. Supendi, K. Nirmala

“…Two third of packing plastic volume was filled by oxygen, and Corydoras aenus 20 fish/pack.  Packing plastic was placed into styrofoam and ice was added to maintain at low temperature.  …”
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mTOR downregulation promotes anti-inflammatory responses via the CCL3-CCR5 axis in hypoxic retinopathy by Tae Kwon Moon, Im Kyeung Kang, Kyoung Jin Lee, Ji Hyun Kim, Hee Jong Kim, A. Reum Han, Ha-Na Woo, Joo Yong Lee, Jun-Sub Choi, Keerang Park, Heuiran Lee

“…To investigate AAV2-shmTOR’s impact on atypical inflammation in these conditions, we employed an in vivo model of oxygen-induced retinopathy and an in vitro model using rMC1 Müller cells. …”
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Galectin-3 secreted by triple-negative breast cancer cells regulates T cell function by Annat Raiter, Yael Barhum, Julia Lipovetsky, Chen Menachem, Sharona Elgavish, Shmuel Ruppo, Yehudit Birger, Shai Izraeli, Orna Steinberg-Shemer, Rinat Yerushalmi

“…Similarly, in our in-vitro model, the decreased expression of oxidative phosphorylation genes and mitochondrial dysfunction resulted in a significant increase in CD8 intracellular reactive oxygen species. Consequently, T exhausted cells (CD8/PD1/Tim3/Lag3+) significantly increased in PBMC co-cultured with Gal-3pos TNBCs.To conclude, we revealed a novel TNBC-related Gal-3 suppressor mechanism that involved upregulation of CD4 T regulatory and of CD8 T exhausted cells.…”
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NIR-triggered programmable nanomotor with H2S and NO generation for cascading oncotherapy by three-pronged reinforcing ICD by Jinlong Zhang, Quan Jing, Longlong Yuan, Xianhui Zhou, Duolong Di, Jinyao Li, Dong Pei, Zhongxiong Fan, Jun Hai

“…In this study, a near-infrared (NIR)-triggered programmable nanomotor with hydrogen sulfide (H2S) and nitric oxide (NO) generation is well designed to achieve oncotherapy by cascading mild photothermal, gas, and reactive oxygen species (ROS)-reinforced immunogenic cell death. …”
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Speciation Analysis of Arsenic Compounds by High-Performance Liquid Chromatography in Combination with Inductively Coupled Plasma Dynamic Reaction Cell Quadrupole Mass Spectrometry... by Hai Anh Vu, Manh Ha Nguyen, Hong-An Vu-Thi, Quan Do-Hong, Xuan Hoang Dang, Thi Ngoc Bich Nguyen, Hong Quan Trinh, Thuy Ly Bich, Tien-Thanh Nguyen, Dung Le-Van, Minh Binh Tu, Dinh Binh Chu

“…Arsenic compounds were detected online by inductively coupled plasma dynamic reaction cell quadrupole mass spectrometry utilizing oxygen as the reaction gas at a flow rate of 0.7 mL·min−1. …”
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Metformin blocks BIK1-mediated CPK28 phosphorylation and enhances plant immunity by Yazhou Bao, Qian Zhang, Hai Zhu, Yong Pei, Yaning Zhao, Yixin Li, Peiyun Ji, Dandan Du, Hao Peng, Guangyuan Xu, Xiaodan Wang, Zhiyuan Yin, Gan Ai, Xiangxiu Liang, Daolong Dou

“…Methods: To investigate the impact of MET on enhancing plant immune responses, we conducted assays measuring defense gene expression, reactive oxygen species (ROS) accumulation, mitogen-activated protein kinase (MAPK) phosphorylation, and pathogen infection. …”
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