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2921
Ethanolic extract of Dayak onion (Eleutherine palmifolia) prevented sperm membran damage in mice exposed to monosodium glutamate
Published 2024-11-01“…Monosodium glutamate (MSG) could cause increased production of reactive oxygen species (ROS), causing oxidative stress in the testicles, which adversely affected sperm quality. …”
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2922
Investigating the antioxidant and anti-inflammatory potential of Nypa fruticans: a multifaceted approach to skin protection and aging
Published 2025-01-01“…Abstract Reactive oxygen species (ROS) produced in the mitochondria of skin cells play a significant role in the degradation of the extracellular matrix and induction of inflammatory responses, both of which are major contributors to skin aging. …”
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2923
Advances in the treatment of glioma-related signaling pathways and mechanisms by metformin
Published 2025-01-01“…Metformin’s inhibition of glioma proliferation involves complex cellular processes, including mitochondrial dysfunction, increased reactive oxygen species (ROS) production, and modulation of immune responses. …”
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2924
Resveratrol Alleviates NEFA-Induced Oxidative Damage in Bovine Mammary Epithelial Cells by Restoring Mitochondrial Function
Published 2025-01-01“…The results showed that RES ameliorated NEFA-induced oxidative damage by upregulating antioxidant enzyme expression and reducing malondialdehyde (MDA) and reactive oxygen species (ROS). Furthermore, exogenous NEFAs resulted in a decrease in mitochondrial membrane potential (MMP), cellular adenosine triphosphate (ATP) production, energy metabolism (NAD<sup>+</sup>/NADH ratio), abnormal mitochondrial structure and an increase in apoptosis levels. …”
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2925
Verbascoside Inhibits the Activation of NLRP3 Inflammasome and Improves BV-2 Cell Inflammatory Damage
Published 2025-02-01“…Methods: A model of inflammatory damage induced by oxygen-glucose deprivation (OGD) in BV-2 cells was employed. …”
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2926
Eco-Friendly Synthesis of Zirconium Dioxide Nanoparticles from <i>Toddalia asiatica</i>: Applications in Dye Degradation, Antioxidant and Antibacterial Activity
Published 2025-01-01“….% zirconium (Zr) and 62.82 mol.% oxygen. The ZrO<sub>2</sub> NPs demonstrated remarkable photocatalytic activity, degrading over 95% of methylene blue dye after 3 h of sunlight exposure. …”
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2927
Protective effect of brain and muscle arnt-like protein-1 against ethanol-induced ferroptosis by activating Nrf2 in mice liver and HepG2 cells
Published 2023-11-01“…Upon exposure to alcohol (5 % Lieber-DeCarli liquid alcohol diet for 10 days before binged alcohol with 5 g/kg body weight in vivo, 300 mmol/L for 12 h in vitro, respectively), the content of iron, reactive oxygen species (ROS) and malondialdehyde (MDA) was boosted significantly while glutathione (GSH) was decreased that mainly based on the downregulated protein expression of ferritin heavy chain (FTH), ferroportin (FPN), heme oxygenase1(HO-1) and anti-cystine/glutamate antiporter (SLC7A11), while these changes could be abolished by ferroptosis inhibitor Ferrostatin-1[Fer-1 (5 mg/kg body weight for 10 days in vivo, 10 μmol/L for 2 h in vitro, respectively)]. …”
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2928
Association Study between Novel CYP26 Polymorphisms and the Risk of Betel Quid-Related Malignant Oral Disorders
Published 2015-01-01“…BQ chewing may produce significant amounts of reactive oxygen species (ROS), resulting in oral mucosa damage, and ROS may be metabolized by CYP26 families. …”
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2929
TAK-242 improves sepsis-associated acute kidney injury in rats by inhibiting the TLR4/NF-κB signaling pathway
Published 2024-12-01“…Finally, the expression of proteins related to the TLR4/NF-κB signaling pathway was observed by western blot.Results Compared with the CLP + vehicle and CLP + TAK-242 groups, the CLP + TAK-242 group reduced blood urea nitrogen (BUN), creatinine (Cr), cystatin-C (Cys-C), reactive oxygen species (ROS), malondialdehyde (MDA), and inflammatory factors levels (p < 0.01), as well as increased superoxide dismutase (SOD) activity of CLP rats (p < 0.01). …”
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2930
Your brain on art, nature, and meditation: a pilot neuroimaging study
Published 2025-01-01“…The blocks included (1) nature videos, (2) AI-generated digital art (“machine hallucinations” by Refik Anadol), and (3) videos of NASA Webb-produced images of galactic nebulas. Brain oxygen-level dependent (BOLD) images were processed using FSL Version 6.0 and a general linear model (GLM) tested the contrasts between art, nature, and meditation blocks, using a cluster-corrected p-value of 0.05.ResultsCompared to rest, meditation led to BOLD increases in bilateral lateral occipital and fusiform gyri, as well as right postcentral gyrus and hippocampus. …”
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2931
Protective Effects of Chitosan Oligosaccharide Against Lipopolysaccharide-Induced Inflammatory Response and Oxidative Stress in Bovine Mammary Epithelial Cells
Published 2025-01-01“…COS treatment also suppressed excessive reactive oxygen species (ROS) production and restored antioxidant enzyme activity under LPS-induced oxidative stress conditions. …”
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2932
Nursing Skill Assessment of Hospital Nurses in Management of Critically Ill Patients
Published 2022-01-01“…The rescue time of cardiopulmonary resuscitation, oxygen inhalation, venous opening, and endotracheal resuscitation in the observation group was 3.24±1.01, which is lower than that in the control group, 6.65±2.11, with statistical significance (P<0.05). …”
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2933
Lead toxicity in Nicotiana tabacum L.: Damage antioxidant system and disturb plant metabolism
Published 2025-02-01“…These results indicate that increasing the content of photosynthetic pigments and hormones, clearing reactive oxygen species by enhancing antioxidant enzyme activity, and improving amino acid metabolism may play an important role in reducing the toxicity of Pb to tobacco.…”
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2934
Sulfated Cyclocarya paliurus polysaccharides exert immunomodulatory potential on macrophages via Toll-like receptor 4 mediated MAPK/NF-κB signaling pathways
Published 2024-01-01“…Meanwhile, SCP3 could activate mitogen-activated protein kinase (MAPK) and nuclear factor kappa B (NF-κB) signaling pathways, which increased the phosphorylation of Erk1/2, JNK, p38 and NF-κB p65, promoting secretion of cytokines tumor necrosis factor α (TNF-α), interleukin 6 (IL-6) and nitric oxide (NO) as well as the production of reactive oxygen species (ROS). In addition, Toll-like receptor 4 (TLR4) receptor inhibitors were able to block the production of NO and TNF-α by SCP3-stimulated macrophages. …”
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2935
An ATP-activated spatiotemporally controlled hydrogel prodrug system for treating multidrug-resistant bacteria-infected pressure ulcers
Published 2025-03-01“…Subsequently, the bacteria-secreted ATP prompts the degradation of IZPP, allowing the loaded IAA prodrug and nanozyme to encounter spatiotemporally on a single carrier, thereby efficiently generating reactive oxygen species (ROS). Exposure to 808 nm near-infrared light enhances the catalytic reaction speed, boosting ROS levels for stronger antibacterial action. …”
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2936
Efficacy, efficiency and safety of a cardiac telerehabilitation programme using wearable sensors in patients with coronary heart disease: the TELEWEAR-CR study protocol
Published 2022-06-01“…The primary outcomes will be the assessment of cardiorespiratory fitness, expressed as peak oxygen uptake assessed by the CPET test and the 6 min walk test. …”
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2937
Anti-Inflammatory and Prebiotic Potential of Ethanol Extracts and Mucilage Polysaccharides from Korean Yams (<i>Dioscorea polystachya</i> and <i>Dioscorea bulbifera</i>)
Published 2025-01-01“…Among the extracts, the 95% ethanol extract exhibited the most potent inhibition of reactive oxygen species (ROS) and nitric oxide (NO) production, warranting further exploration of its mechanisms of action. …”
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2938
Comparison of Nasopharyngeal Airway with Endoscopic Respiratory Mask for Hypoxemia in Painless Gastrointestinal Endoscopy in Obese Outpatients: Study Protocol for a Randomized Cont...
Published 2025-02-01“…Patients in group N will undergo intubation of the nasopharyngeal airway prior to examination, whereas patients in group C will receive oxygen therapy through an endoscopic respiratory mask at a flow rate of 10 L/min during the procedure. …”
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2939
Aminoguanidine hemisulfate improves mitochondrial autophagy, oxidative stress, and muscle force in Duchenne muscular dystrophy via the AKT/FOXO1 pathway in mdx mice
Published 2025-01-01“…This study investigates the effects of aminoguanidine hemisulfate (AGH), an inhibitor of reactive oxygen species (ROS), on mitochondrial autophagy, oxidative stress, and muscle force in mdx mice. …”
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2940
Moxibustion Regulates the BRG1/Nrf2/HO-1 Pathway by Inhibiting MicroRNA-222-3p to Prevent Oxidative Stress in Intestinal Epithelial Cells in Ulcerative Colitis and Colitis-Associat...
Published 2024-01-01“…With changes in reactive oxygen species (ROS), malondialdehyde (MDA), glutathione peroxidase (GSH-Px), and inflammatory cytokines interleukin (IL)-1β and tumor necrosis factor (TNF)-α), we verified that HPM protects against oxidative stress and inflammation in IECs of UC and CAC mice. …”
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