Hyaluronic acid-curcumin nanoparticles for preventing the progression of experimental autoimmune uveitis through the Keap1/Nrf2/HO-1 signaling pathway by Weiwei Tang, Xiaomin Huang, Yun-Di Yi, Fan Cao, Manli Deng, Jiawei Fan, Zheng-Xuan Jiang, Li-Ming Tao, Xianwen Wang, Lei Shi

“…Although curcumin (CUR) has prominent antioxidant capacity and reactive oxygen species (ROS) scavenging ability, its low bioavailability and undetermined mechanisms limit its extensive application. …”
Get full text

Simultaneous exposure to microplastics and heavy metal lead induces oxidative stress, histopathological damage, and immune dysfunction in marine mussel Mytilus coruscus by Chuanyue Chen, Xueer Wang, Yingrong Jin, Yinchang Yao, Suchang Li, Zhi Liao, Xiaolin Zhang, Xiaojun Yan

“…Meanwhile, co-exposure poses a significant threat to the immune function of the mussels, as evidenced by induction of hemocytes to produce excess reactive oxygen species (ROS), significantly reducing lysosome activity (p < 0.05), inhibiting the expression of autophagy-related genes, and inducing the expression of apoptosis-related genes, resulting in hemocyte apoptosis. …”
Get full text

Heliox Improves Carbon Dioxide Removal during Lung Protective Mechanical Ventilation by Charlotte J. Beurskens, Daniel Brevoord, Wim K. Lagrand, Walter M. van den Bergh, Margreeth B. Vroom, Benedikt Preckel, Janneke Horn, Nicole P. Juffermans

“…Twenty-four ICU patients were included, who were admitted after a cardiac arrest and mechanically ventilated for 3 hours with heliox (50% helium; 50% oxygen). A fixed protective ventilation protocol (6 mL/kg) was used, with prospective observation for changes in lung mechanics and gas exchange. …”
Get full text

Derivation and Characterization of Isogenic <i>OPA1</i> Mutant and Control Human Pluripotent Stem Cell Lines by Katherine A. Pohl, Xiangmei Zhang, Johnny Jeonghyun Ji, Linsey Stiles, Alfredo A. Sadun, Xian-Jie Yang

“…Furthermore, <i>OPA1</i> mutant PSCs exhibited reduced rates of oxygen consumption and ATP production associated with mitochondria. …”
Get full text

Superoxide dismutase promotes gastric tumorigenesis mediated by Helicobacter pylori and enhances resistance to 5-fluorouracil in gastric cancer by Hongbing Fu, Yu Zhang, Yantao Duan, Xin Zhang, Jun Yao, Dejun Yang, Ziran Wei, Zhenxin Zhu, Jiapeng Xu, Zunqi Hu, Qing You, Ronglin Yan, Weijun Wang

“…Knockdown of SOD2 led to increased levels of reactive oxygen species and oxidative stress in response to H. pylori infection. …”
Get full text

Community structure and diversity of meiofauna in seagrass beds on the eastern coast of Hainan Island, China by Kai Liu, Yuqing Guo, Mingming Zou, Weilin Chen, Wenjia Hu, Jianguo Du

“…Furthermore, environmental factors such as dissolved oxygen and chlorophyll content were found to significantly influence the distribution of nematodes and polychaetes. …”
Get full text

FTO attenuates TNF-α-induced damage of proximal tubular epithelial cells in acute pancreatitis-induced acute kidney injury via targeting AQP3 in an N6-methyladenosine-dependent man... by Xinghui Li, Qi Liang, Lu Liu, Shujun Chen, Yong Li, Yu Pu

“…The viability and apoptosis of PTECs under various conditions, and reactive oxygen species (ROS), superoxide dismutase (SOD), and malonaldehyde (MDA) levels within these cells were measured using commercial assay kits and flow cytometry. …”
Get full text

Chitosan oligosaccharide alleviates DON-induced liver injury via suppressing ferroptosis in mice by Mengjie Liu, Zhenlin Li, Jie Li, Guorong Yan, Chaoqi Liu, Qingqiang Yin, Yeqiang Liu, Xiaoxiang Xu

“…Moreover, COS significantly reduced liver reactive oxygen species (ROS) levels, malondialdehyde (MDA) content, and lactate dehydrogenase (LDH) release in DON-exposed mice, while restoring the activity of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px) and total antioxidant capacity (T-AOC). …”
Get full text

Multicentre, randomised controlled trial to investigate the effects of parental touch on relieving acute procedural pain in neonates (Petal) by Eleri Adams, Daniel Crankshaw, Ria Evans Fry, Rebeccah Slater, Caroline Hartley, Maria M Cobo, Fiona Moultrie, Annalisa G V Hauck, Vaneesha Monk, Shellie Robinson, Marianne van der Vaart, Luke Baxter, Ravi Poorun, Aomesh Bhatt

“…We will record brain activity (EEG), cardiac and respiratory dynamics, oxygen saturation and facial expression to provide proxy pain outcome measures. …”
Get full text

Novel Electrochemical Treatment of Spent Caustic from the Hydrocarbon Industry Using Ti/BDD by Alejandro Medel, Erika Méndez, José L. Hernández-López, José A. Ramírez, Jesús Cárdenas, Roberto F. Frausto, Luis A. Godínez, Erika Bustos, Yunny Meas

“…The potential production of •OHs, as the main reactive oxygen species electrogenerated over Ti/BDD surface, was evaluated in HCl and H2SO4 through fluorescence spectroscopy, demonstrating the reaction medium’s influence on its production. …”
Get full text

β-Nicotinamide Mononucleotide Reduces Oxidative Stress and Improves Steroidogenesis in Granulosa Cells Associated with Sheep Prolificacy via Activating AMPK Pathway by Yu Cai, Hua Yang, Hui Xu, Shanglai Li, Bingru Zhao, Zhibo Wang, Xiaolei Yao, Feng Wang, Yanli Zhang

“…NMN treatment effectively reduced Lipopolysaccharide (LPS)-induced apoptosis and mitigated mitochondrial dysfunction, while also decreasing the production of reactive oxygen species (ROS), thereby enhancing the activity of the antioxidant defense system. …”
Get full text

Airway morphology, hyoid position, and serum inflammatory markers of obstructive sleep apnea in children treated with modified twin-block appliances by Jun Duan, Wanyuan Xia, Xuelei Li, Feng Zhang, Fan Wang, Mengwei Chen, Qian Chen, Bing Wang, Bing Li

“…Results Following MTBA management, the experimental group exhibited decreased apnea–hypopnea index and increased lowest arterial oxygen saturation level (P < 0.05). Sella- and subspinale-nasion-supramental angles significantly increased and decreased, respectively (P < 0.05). …”
Get full text

The Effect of Buriti Oil (Mauritia flexuosa L.) as Feed Additive on the Organic and Inorganic Materials Digestibility on Heat Stress Exposed Broilers by Burhanudin, Sunaryo Hadi Warsito, Bodhi Agustono, Nusdianto Triakoso, Ragil Angga Prastiya, Faisal Fikri

“…Buriti oil (Mauritia flexuosa L.) contains antioxidants that can suppress Reactive Oxygen Species (ROS) thereby reducing the negative effects of heat stress. …”
Get full text

Next-generation calcium oxide nanoparticles: A breakthrough in energy storage and humidity sensing by Asif Khan, Syed Tasleem Hussain, Abdul Naeem, Ayesha Sadiqa, Awais Ahmad, Muhammad Aamir Ali Shehzada, Munirah D. Albaqami

“…XPS analysis confirmed that the sample was mainly composed of calcium [25.34 %], and oxygen [63.53 %]. TGA showed two significant weight losses, the former 9.81 % at 390–420 °C due to thermal decomposition of calcium hydroxide to calcium oxide and water and the later 18.98 % at 600–700 °C due to removal of chemical adsorbed water molecules and disintegration of the left over CaCO3. …”
Get full text

Dexmedetomidine pretreatment enhances protective effect efficacy of pericytes agaist acute lung injury in septic mice by LUO Xi, ZHANG Zisen, YANG Ao

“…After PCs and Dex-PCs were exposed to 10 μg/mL LPS， the level of intracellular reactive oxygen species （ROS） was measured.　‍Results　‍Compared with the Sham group， the ALI group had increased permeability of pulmonary vascular endothelial cells， extensive extravasation of Evans blue， severely destructed of lung tissue structure and massive inflammatory cell infiltration， higher lung wet/dry weight ratio， elevated serum TNF-α and IL-6 levels， and declined lung function， and no mice survived for 72 h after modeling （P<0.05）. …”
Get full text

The Effect of Lithium on Inflammation-Associated Genes in Lipopolysaccharide-Activated Raw 264.7 Macrophages by Raymond T. Makola, Vusi G. Mbazima, Matlou P. Mokgotho, Vincent S. Gallicchio, Thabe M. Matsebatlela

“…A reduced internal H2DCFDA fluorescence intensity, indicative of reduced reactive oxygen species (ROS) production, was observed in LPS-activated Raw 264.7 macrophages treated with lithium. …”
Get full text

De novo assembly and analysis of the transcriptome of the Siberian wood frog Rana amurensis by D. N. Smirnov, S. V. Shekhovtsov, A. A. Shipova, G. R. Gazizova, E. I. Shagimardanova, N. A. Bulakhova, E. N. Meshcheryakova, T. V. Poluboyarova, E. E. Khrameeva, S. E. Peltek, D. I. Berman

“…It can survive for several months in an almost complete absence of oxygen. Little is known about the mechanisms of this remarkable resilience, in part because studies of amphibian genomes are impeded by their large size. …”
Get full text

The interplay of ferroptosis and oxidative stress in the pathogenesis of aortic dissection by Zhaoshan Zhang, Zhaoshan Zhang, Zhaoshan Zhang, Haichao Wang, Haichao Wang, Haichao Wang, Xi Kan, Xi Kan, Xi Kan, Xiaozhao Zhang, Xiaozhao Zhang, Xiaozhao Zhang, Senping Xu, Senping Xu, Senping Xu, Jie Cai, Jie Cai, Jie Cai, Jiawei Guo, Jiawei Guo, Jiawei Guo

“…Ferroptosis, a form of iron-dependent programmed cell death, occurs alongside lipid peroxidation and the accumulation of reactive oxygen species (ROS). The relationship between ferroptosis and AD lies in its damaging effect on vascular cells. …”
Get full text

Over-Expression of MicroRNA-210 and MicroRNA-185-5p in Normotensive Late-Fetal Growth Restriction: Preliminary Cohort Study by Esra Altan Erbilen, Gulizar Fusun Varol, Necdet Sut, Nebiye Pelin Turker, Niyazi Cenk Sayin

“… OBJECTIVE: Late Fetal Growth Restriction (LFGR), a condition associated with perinatal and long-term neurodevelopmental problems, is caused by inadequate placental transfer of oxygen and nutrients to the fetus. This preliminary study evaluates the expression profiles and clinical significance of hypoxia-sensitive microRNA-210 (miR-210) and microRNA-185-5p (miR-185-5p) in placental and maternal circulation. …”
Get full text

Synergistic anti-oxidative/anti-inflammatory treatment for acute lung injury with selenium based chlorogenic acid nanoparticles through modulating Mapk8ip1/MAPK and Itga2b/PI3k-AKT... by Huizhen Xing, Xinwei Bai, Xiaoying Pei, Yuqi Zhang, Xueying Zhang, Shujun Chen, Dan Li, Bin Lv, Xiaoying Wang, Xiaoli Wu

“…The CHSe NPs exhibited superoxide dismutase(SOD) like and glutathione peroxidase(GPX) like activities, effectively scavenging various types of reactive oxygen species (ROS), and inhibited the inflammatory response of macrophages. …”
Get full text