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2701
Mechanisms of Copper-Induced Autophagy and Links with Human Diseases
Published 2025-01-01“…However, excess intracellular copper can induce cell death due to its potential to catalyze the generation of reactive oxygen species, thus copper homeostasis is strictly regulated. …”
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2702
lncRNA NEAT1 Downregulation Ameliorates the Myocardial Infarction of Mice by Regulating the miR-582-5p/F2RL2 Axis
Published 2022-01-01“…The infarct area, pathological changes, and cell apoptosis in mouse myocardial tissue were evaluated using triphenyltetrazolium chloride and Evans blue, hematoxylin-eosin, and TUNEL staining assays. Oxygen-glucose deprivation- (OGD-) induced human cardiac myocytes (HCMs) were cultured and transfected. …”
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2703
The clinical features and outcomes of diabetes patients infected with COVID-19: a systematic review and meta-analysis comprising 192,693 patients
Published 2025-01-01“…Compared with the non-diabetic group, the diabetic group had a higher incidence of complications in acute respiratory distress syndrome (ARDS), shock, acute heart injury, acute kidney injury and more regularly used oxygen therapy, invasive ventilation, non-invasive ventilation, continuous renal replacement therapy (CRRT), extracorporeal membrane oxygenation (ECMO) treatment. …”
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2704
Confronting the anxiety of Generation Z: electroacupuncture therapy regulates oxidative stress and microglia activity in amygdala-basolateral of socially isolated mice
Published 2025-02-01“…Additionally, biochemical analyses and immunofluorescence imaging were performed to assess the expression of NADPH oxidase 2 (NOX2), microglial activation markers, and levels of oxidative stress.ResultsOur findings reveal that EA treatment significantly mitigates anxiety-like behaviors in mice, correlating with a reduction in NOX2 expression within BLA microglia and decreased levels of reactive oxygen species (ROS). Furthermore, EA was observed to restore normal microglial morphology, indicating its potential role in modulating microglial activity.DiscussionThe results of this study suggest that EA exerts its anxiolytic effects through the modulation of oxidative stress and the activity of microglia in the BLA. …”
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2705
Propofol Reduces Lipopolysaccharide-Induced, NADPH Oxidase (NOX2) Mediated TNF-α and IL-6 Production in Macrophages
Published 2013-01-01“…During an infection, lipopolysaccharide (LPS) stimulates the production of reactive oxygen species (ROS), which is mediated, in large part, by nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (NOXs); NOX2 is the major NOX isoform found in the macrophage cell membrane. …”
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2706
Study on Mechanical Properties and Fire Resistance of Epoxy Nanocomposite Reinforced with Environmentally Friendly Additive: Nanoclay I.30E
Published 2020-01-01“…The results showed that epoxy Epikote 240/nanoclay I.30E nanocomposite material had mechanical properties and improved fire retardancy with a small amount of nanoclay I.30E added (2% by weight): tensile strength of 63.5 MPa (increased by 13.59%), flexural strength of 116.80 MPa (increased by 34.63%), compressive strength of 179.67 MPa (increased by 15.11%), impact resistance Izod of 12.81 KJ/m2 (increased by 80.16%), oxygen limit of 23.7%, and combustion rate of 24.5 mm/min; according to UL 94HB, the combustion rate reached 22.59 mm/min.…”
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2707
Antifungal Activity of Gelatin-Tapioca Starch Film and Coating Containing Copper Nanoparticles against Colletotrichum gloeosporioides Causing Anthracnose
Published 2020-01-01“…For the in vivo antifungal tests on mangoes, both the control and the CuNPs-containing coatings equally inhibit fungal growth, possibly due to the low oxygen permeability of the protein and starch components in the films. …”
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2708
Unveiling molecular insights: in silico exploration of TLR4 antagonist for management of dry eye syndrome
Published 2024-05-01“…It is identified by the excessive buildup of reactive oxygen species, leading to substantial corneal epithelial cell demise and ocular surface inflammation attributed to TLR4. …”
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2709
Continuous Consumption of Reused Palm Oil Induced Hepatic Injury, Depletion of Glutathione Stores, and Modulation of Cytochrome P450 Profiles in Mice
Published 2019-01-01“…Cooking oil deteriorates with repeated thermal exposure, resulting in appearance change and formation of oxygen radicals. Consumption of the deteriorated oil causes oxidative stress related to lipid metabolism. …”
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2710
The Impact of Silymarin on Inflammation and Oxidative Stress: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Published 2025-01-01“…Numerous studies have investigated into the antioxidant and anti-inflammatory properties of silymarin, as well as its ability to reduce reactive oxygen species and inflammation biomarkers. The effect of silymarin on inflammation and oxidative stress was investigated using the keywords “milk thistle” OR “Silybum marianum” OR “Silybum” OR “silymarin” OR “Silibinin” AND “MDA” OR “Malondialdehyde” OR “TAC” OR “total antioxidant capacity” OR “IL-10” OR “Interleukin-10” OR “IL-6” OR “Interleukin-6” OR “TNF-α” OR “tumor necrosis factor alpha” on the Web of Science, Scopus, Embase, PubMed, and Cochrane Library, up until March 2023. …”
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2711
Bioenergy potential of Chlorella vulgaris under the influence of different light conditions in a bubble column photobioreactor
Published 2023-10-01“…Moreover, in the blue light condition, scanning electron microscopy analysis showed no significant changes in the shape of Chlorella vulgaris and energy-dispersive X-ray analysis elemental composition exhibited the lowest oxygen-to-carbon ratio (1.03). Fourier transform infrared spectroscopy was used to illustrate the functional group of microalgae under different lighting conditions. …”
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2712
The Binding of BF-227-Like Benzoxazoles to Human α-Synuclein and Amyloid β Peptide Fibrils
Published 2018-09-01“…A similar or lower ratio was measured for analogues decorated with alkyl or oxyethylene chains attached to the oxygen at the 6 position of BF-227, suggesting a lack of involvement of the side chain in fibril binding. …”
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2713
Subtoxic Concentrations of Hepatotoxic Drugs Lead to Kupffer Cell Activation in a Human In Vitro Liver Model: An Approach to Study DILI
Published 2015-01-01“…KC activation was investigated by the measurement of reactive oxygen intermediates (ROI, DCF assay) and cell activity (XTT assay). …”
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2714
Neurotoxic Effect of Myricitrin in Copper-Induced Oxidative Stress Is Mediated by Increased Intracellular Ca<sup>2+</sup> Levels and ROS/p53/p38 Axis
Published 2025-01-01“…The myricitrin-induced decrease in survival was accompanied with increased reactive oxygen species (ROS) production, reduced superoxide dismutase activity, and a lower GSH/GSSG ratio. …”
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2715
Effects of the Photosystem II Inhibitors CCCP and DCMU on Hydrogen Production by the Unicellular Halotolerant Cyanobacterium Aphanothece halophytica
Published 2019-01-01“…One factor limiting the H2 photoproduction of this cyanobacterium is an inhibition of bidirectional hydrogenase activity by oxygen (O2) obtained from splitting water molecules via photosystem II activity. …”
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2716
Ugochukwu, Oliver Ukachi
Published 2024“…Malondialdehyde, liver enzymes, reactive oxygen species, total bilirubin, and direct bilirubin levels were all significantly elevated by BPA (p 0.05). …”
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2717
Assessment of Physicochemical Parameters of Harvested Rainwater in Hamuhambo Town Council Rubanda District.
Published 2025“…The study accessed some of the physicochemical parameters such as pH, Temperature, turbidity, Electrical conductivity, Dissolved Oxygen, and TDS across eight stations that included 3 community tanks (at a primary school, at a church, and a health center III hospital) and 5 individual household tanks by sampling once after eight weeks of harvest and storage of rainwater, to establish the water quality as there is a risk of contamination during harvesting and storing. …”
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2718
Astaxanthin-loaded brain-permeable liposomes for Parkinson’s disease treatment via antioxidant and anti-inflammatory responses
Published 2025-02-01“…In vitro, Lf-ASX-LPs reduced cell loss by 20.1% and oxygen species by 30.0%, ameliorated the reduction in mitochondrial membrane potential under 1-methyl-4-phenylpyridinium-induced toxicity by 40.1%, and reduced extracellular nitric oxide levels under lipopolysaccharide-induced toxicity by 32.0%, indicating cytoprotective and antioxidant effects. …”
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2719
Ginsenoside Rk2 alleviates hepatic ischemia/reperfusion injury by enhancing AKT membrane translocation and activation
Published 2025-01-01“…Rk2 significantly reduced inflammation and apoptosis caused by oxygen‐glucose deprivation and reperfusion in hepatocytes and dose dependently protected against hepatic I/R‐induced liver injury in mice. …”
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2720
Characterization and Otoprotective Effects of Polysaccharides from <i>Arthrospira platensis</i>
Published 2025-01-01“…The recent literature reported that hearing loss is promoted by an excessive generation of reactive oxygen species (ROS) in cochlea cells, which causes oxidative stress. …”
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