Alpha Mangostin Inhibits the Proliferation and Activation of Acetaldehyde Induced Hepatic Stellate Cells through TGF-β and ERK 1/2 Pathways by Novriantika Lestari, Melva Louisa, Vivian Soetikno, Averina Geffanie Suwana, Putra Andito Ramadhan, Taufiq Akmal, Wawaimuli Arozal

“…These findings were followed with decreased expressions and concentrations of TGF-β; decreased expression of Col1A1, TIMP1, and TIMP3; increased expression of MnSOD and GPx; and reduction in intracellular reactive oxygen species. These effects were shown to be dose dependent. …”
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Engineering Magnetic Heterostructures with Synergistic Regulation of Charge‐Transfer and Spin‐Ordering for Enhanced Water Oxidation by Chongyan Hao, Yang Wu, Xiaobo Zheng, Yumeng Du, Yameng Fan, Weikong Pang, Anton Tadich, Shujun Zhang, Thomas Frauenheim, Tianyi Ma, Xiaoning Li, Zhenxiang Cheng

“…In this study, a novel magnetic heterostructure, CoFe2O4@CoFeMo3O8, is designed to simultaneously modulate charge and spin characteristics, and systematically elucidated their synergistic impact on the oxygen evolution reaction (OER). Experimental results and density functional theory calculations confirmed that the magnetic heterostructure exhibits both charge transfer and spin polarization. …”
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Anatomical and physiological features of the right heart affecting the effectiveness of balloon valvuloplasty and increase the risk of repeated interventions in children with valvu... by Yu.L. Kuzmenko, A.A. Dovhaliuk, M.P. Radchenko, O.О. Motrechko

“…The procedure was considered to be effective in such cases: (1) the pressure gradient between the right ventricle and pulmonary artery was reduced by more than 30 % compared to the initial, (2) the systolic pressure in the abdominal wall decreased by more than 30 %, (3) there was an increase in the level of oxygen saturation of arterial blood (more than 10 %) in patients with baseline low levels. …”
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Metabolic consequences of erastin-induced ferroptosis in human ovarian cancer cells: an untargeted metabolomics study by Kaylie I. Kirkwood-Donelson, Alan K. Jarmusch, Carl D. Bortner, Bruce Alex Merrick, Birandra K. Sinha

“…Erastin (ER), a ferroptosis inducer, kills tumor cells by generating and accumulating reactive oxygen species (ROS) within the cell, resulting in an iron-dependent oxidative damage-mediated ferroptotic cell death.MethodsWe have utilized human ovarian cancer cell lines, OVCAR-8 and its adriamycin-selected, multi-drug resistance protein (MDR1)-expressing NCI/ADR-RES, both equally sensitive to ER, to identify metabolic biomarkers of ferroptosis.ResultsOur studies showed that ER treatment rapidly depleted cellular glutathione and cysteine and enhanced formation of ophthalamate (OPH) in both cells. …”
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Immunomodulation effects of collagen hydrogel encapsulating extracellular vesicles derived from calcium silicate stimulated-adipose mesenchymal stem cells for diabetic healing by Yen-Hong Lin, Yeh Chen, En-Wei Liu, Mei-Chih Chen, Min-Hua Yu, Cheng-Yu Chen, Chia-Che Ho, Tai-Yi Hsu-Jiang, Jian-Jr Lee, Der-Yang Cho, Ming-You Shie

“…In vitro, CSEV-loaded collagen significantly reduced reactive oxygen species production, promoted cell proliferation and migration compared to standard EV-loaded collagen. …”
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The Protective Effect of Docosahexaenoic Acid on Mitochondria in SH-SY5Y Model of Rotenone-Induced Toxicity by Britta Eggers, Jennifer Stepien, Anne-Katrin Reker, Svenja Esser, Kathy Pfeiffer, Magdalena Pawlas, Katalin Barkovits, Katrin Marcus

“…<b>Results:</b> We confirmed a reduced cell viability and an increased abundance of reactive oxygen species upon rotenone treatment, DHA pre-treatment was shown to decrease said species. …”
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Effect of ultrasonic modification on the protective activity of Flammulina velutipes polysaccharide to prevent ethanol-induced injury on GES-1 cells by Jinrong Xiao, Xin Chen, Jingsi Zhang, Yifan Wang, Lei Zhong, Qiping Zhan, Qiuhui Hu, Liyan Zhao

“…With increasing ultrasound intensity, the protective effect of FVPs on GES-1 cells was significantly enhanced by more effective prevention of intracellular reactive oxygen species (ROS) production and more promotion of expression of triglyceride factor 2 (TFF2), prostaglandin E2 (PGE2), epidermal growth factor (EGF), and transforming growth factor β1 (TGF-β1) mRNA. …”
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Prediction of Final Phosphorus Content of Steel in a Scrap-Based Electric Arc Furnace Using Artificial Neural Networks by Riadh Azzaz, Mohammad Jahazi, Samira Ebrahimi Kahou, Elmira Moosavi-Khoonsari

“…Data were collected over one year from a steel plant, focusing on parameters such as the chemical composition and weight of the scrap, the volume of oxygen injected, injected lime, and process duration. …”
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Identification of key genes associated with oxidative stress in ischemic stroke via bioinformatics integrated analysis by Gaiyan Li, Yu Cheng, Shanshan Ding, Qianyun Zheng, Lanqiong Kuang, Ying Zhang, Ying Zhou

“…Enrichment analysis indicated that the key genes were associated with oxidative stress, reactive oxygen species, lipid and atherosclerosis, and cell migration-related pathways. …”
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Age-Related Macular Degeneration: Insights into Inflammatory Genes by Raffaella Cascella, Michele Ragazzo, Claudia Strafella, Filippo Missiroli, Paola Borgiani, Francesco Angelucci, Luigi Tonino Marsella, Andrea Cusumano, Giuseppe Novelli, Federico Ricci, Emiliano Giardina

“…In particular, ageing and cigarette smoking (including oxidative compounds and reactive oxygen species) have been shown to significantly increase susceptibility to the disease. …”
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Magnesium hydride protects against acetaminophen-induced acute kidney injury by inhibiting TXNIP/NLRP3/nf-κb pathway by Yachen Si, Lulu Liu, Yinyin Zhang, Hongxia Li, Tingting Zhao, Su Liu, Xuejun Sun, Jin Cheng, Hongtao Lu

“…In addition, the increased level of reactive oxygen species (ROS) and expressions of inflammatory cytokines (TNF-α and IL-1β) and pro-apoptotic factors (Bad, Bax, Caspase3, and CytC) induced by APAP were downregulated with MgH2 treatment. …”
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M6a demethylase FTO regulates the oxidative stress, mitochondrial biogenesis of cardiomyocytes and PGC-1a stability in myocardial ischemia-reperfusion injury by Qiong Jiang, Xuehai Chen, Kezeng Gong, Zhe Xu, Lianglong Chen, Feilong Zhang

“…The generation of reactive oxygen species (ROS) and the levels of superoxide dismutase (SOD2), mitochondrial transcription factor (TFAM) and cytochrome c oxidase I (COXI) were detected to assess the oxidative stress and mitochondrial biogenesis. …”
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Experimental and Modeling Study for the Solar-Driven CO₂ Electrochemical Reduction to CO by Matteo Agliuzza, Roberto Speranza, Andrea Lamberti, Candido Fabrizio Pirri, Adriano Sacco

“…The model includes platinum foil and silver nanoparticles as catalysts for the oxygen evolution reaction and CO₂ reduction reaction, respectively. …”
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Towards sustainable solutions: Comprehensive review of advanced porous materials for CO₂ capture, hydrogen generation, pollutant degradation, and energy application by Iltaf Khan, Anam Altaf, Samreen Sadiq, Shoaib Khan, Aftab Khan, Sohail Khan, Muhammad Humayun, Abbas Khan, Rasha A. Abumousa, Mohamed Bououdina

“…This review article highlights the various types, structures, and synthesis methods of POPs, MOFs, HOFs, COFs, zeolites, and PAFs, in addition to their important applications such as hydrogen generation, gas sensing, CO2 conversion, pollutant degradation, CO2 capture, hydrogen evolution/oxygen evolution reactions, and batteries. Lastly, the future perspective of APMs along with the necessary steps to be taken and embraced in order to make them usable for long-term and large-scale applications will help in opening new innovative gateways to the research field.…”
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Effect of Cl substitution on the microstructure, dielectric and optical properties of CaCu3Ti4O12 ceramics by Najwa. Gouitaa, Sahil Kumar, Fatima Zahra. Ahjyaje, Taj-dine. Lamcharfi, Amina. Benatia, Mustapha. Abarkan, Mamta Shandilya

“…This study investigates the enhanced properties of CaCu3Ti4O12 (CCTO) ceramics by substituting oxygen anions with chlorine to form CaCu3Ti4O10Cl2 (CCTO-Cl2). …”
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Dual Effect of Serum Amyloid A on the Invasiveness of Glioma Cells by Franciele Hinterholz Knebel, Renata Chaves Albuquerque, Renato Ramos Massaro, Silvya Stuchi Maria-Engler, Ana Campa

“…These findings agree with the effect triggered by rSAA on matrix metalloproteinases (MMPs) activities measured in a gelatinolytic assay. rSAA inhibited activity of both MMPs in A172 cells while increasing them in T98G cells. rSAA also affected the production of compounds present in the tumor microenvironment that orchestrate tumor progression, such as IL-8, the production of reactive oxygen species (ROS) and nitric oxide (NO). We also observed that both lines expressed all three of the isoforms of SAA: SAA1, SAA2, and SAA4. …”
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New Insights in the Pathogenesis of HPV Infection and the Associated Carcinogenic Processes: The Role of Chronic Inflammation and Oxidative Stress by Simona Roxana Georgescu, Cristina Iulia Mitran, Madalina Irina Mitran, Constantin Caruntu, Maria Isabela Sarbu, Clara Matei, Ilinca Nicolae, Sandra Milena Tocut, Mircea Ioan Popa, Mircea Tampa

“…Chronic inflammation induces OS, which in turn promotes the perpetuation of the inflammatory process resulting in the release of numerous molecules which cause cell damage. Reactive oxygen species exert a harmful effect on proteins, lipids, and nucleic acids. …”
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Caffeic Acid Phenethyl Ester Regulates PPAR’s Levels in Stem Cells-Derived Adipocytes by Luca Vanella, Daniele Tibullo, Justyna Godos, Francesca Romana Pluchinotta, Claudia Di Giacomo, Valeria Sorrenti, Rosaria Acquaviva, Alessandra Russo, Giovanni Li Volti, Ignazio Barbagallo

“…Quantification of Oil Red O-stained cells showed that lipid droplets decreased following Cape treatment as well as radical oxygen species formation. Additionally, exposure of ASC to high glucose levels decreased adiponectin and increased proinflammatory cytokines mRNA levels, which were reversed by Cape-mediated increase of insulin sensitivity. …”
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Individualized drug therapy and survival prediction in ICU patients with acute kidney injury: construction and validation of a nomogram by Rui Yang, Xiaozhe Su, Ziqi Liu, Shuai Shao, Yinhuai Wang, Hao Su, Haiqing He

“…Results This study enrolled 1,208 patients and developed a nomogram incorporating oxygen flow rate, respiratory frequency, continuous venovenous hemodiafiltration status, age, and medication use (including ibuprofen, epinephrine, cefazolin, warfarin, and vasopressin). …”
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Role of cardiolipin in skeletal muscle function and its therapeutic implications by Youngbum Yoo, MyeongHoon Yeon, Mee-Sup Yoon, Young-Kyo Seo

“…Upregulating CL synthesis enhances mitochondrial function by stabilizing ETC proteins, increasing oxygen flux, and improving cristae architecture. Therapeutic strategies, including CL-targeting compounds like elamipretide and gene therapy, show promise for mitigating sarcopenia by improving mitochondrial bioenergetics and muscle regeneration.…”
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