-
6381
Comparative effect of atorvastatin and risperidone on modulation of TLR4/NF-κB/NOX-2 in a rat model of valproic acid-induced autism
Published 2024-09-01“…Conclusions The research results unequivocally demonstrated that atorvastatin can modulate VPA-induced autism by suppressing inflammation, oxidative stress, and apoptosis through TLR4/NF-κB/NOX-2 signaling pathway. …”
Get full text
Article -
6382
Characteristics of Soil Active Carbon Fractions and Carbon Pool Stability in Major Forest Types in Northern Daxing’an Mountains
Published 2024-12-01“…[Methods] The soil samples of 0-10 and 10-20 cm soil layers were collected from May to September in the growing season from Larix gmelinii, Pinus sylvestris var. mongolica, Betula platyphylla and Populus davidiana forests in the northern part of Daxing’ anling, and the contents of different reactive carbon oxides in the soils were measured by the modified Loginow method, and the active carbon utilisation (ER) and carbon pool activity (CPA) were used to measure the carbon pool stability and the carbon cycle. …”
Get full text
Article -
6383
MT1G promotes iron autophagy and inhibits the function of gastric cancer cell lines by intervening in GPX4/SQSTM1
Published 2024-11-01“…Multiple studies have shown that Metallothionein-1G (MT1G) is closely associated with oxidative stress, ferroptosis, and autophagy. However, the role and potential mechanisms of MT1G in GC have not been fully elucidated. …”
Get full text
Article -
6384
Influence of minor hydrocarbon seepage on sulfur cycling in marine subsurface sediments
Published 2025-02-01“…Metagenomic and metatranscriptomic data indicated metabolic potential and activity towards sulfate reduction and anaerobic oxidation of methane (AOM). Expression of functional marker genes (<i>aprAB</i>, <i>dsrAB</i>, <i>mcrA</i>) revealed metabolic activities by sulfate-reducing Desulfobacterota and methanotrophic ANME-1 archaea sustained by HC traces in the sediment. …”
Get full text
Article -
6385
Enrichment of electrotrophic microorganisms from contrasting shallow-sea hydrothermal environments in bioelectrochemical reactors
Published 2025-02-01“…IntroductionHydrothermal vents are inhabited by electrotrophic microorganisms, which are capable of oxidizing extracellular compounds, such as metals, to power their metabolisms. …”
Get full text
Article -
6386
COPD with Eosinophilic Inflammation is Susceptible to Particulate Air Pollution Exposure
Published 2023-05-01“…Land use regression (LUR) model was used to estimate exposure levels to particulate matter with an aerodynamic diameter of < 10 µm (PM10), PM2.5 (< 10 µm), nitrogen oxides (NOx) and nitrogen dioxides (NO2). We investigated associations of air pollution with COPD outcomes by performing a linear regression approach. …”
Get full text
Article -
6387
Effects of Lupeol on Intestinal Anastomosis After Experimental Intestinal Ischemia-Reperfusion Injury in Rats
Published 2025-01-01“…In this process, anastomotic strength is as important as inflammatory responses and oxidative stress. Therefore, we conducted the study to investigate the effects of lupeol on intestinal ischemia-reperfusion injury, not only biochemically and histopathologically but also on anastomotic strength and miRNAs.Methods: Female rats were randomly divided into six groups. …”
Get full text
Article -
6388
Application of the DEB-TKTD model with multi-omics data: Prediction of life history traits of Chinese mitten crab (Eriocheir sinensis) under different salinities
Published 2025-01-01“…The omics results indicated that at 18 ‰, the osmoregulatory capacity and oxidative stress resistance were enhanced, and vitellogenin synthesis was stimulated. …”
Get full text
Article -
6389
Trade-Off Between Enzymatic Antioxidant Defense and Accumulation of Organic Metabolite Affects Salt Tolerance of White Clover Associated with Redox, Water, and Metabolic Homeostase...
Published 2025-01-01“…However, Trp004 maintained significantly higher leaf relative water content and chlorophyll content as well as lower osmotic potential and oxidative damage, compared with KL under salt stress. …”
Get full text
Article -
6390
Effects of Mn addition on wear and corrosion resistances of AlCoCrFeNi high-entropy alloy coating sprayed by HVOF
Published 2025-01-01“…XPS analysis shows that the Mn addition leads to an increased presence of Cr2O3 in the passivation film on the surface of the coatings, which was more resistant to Cl− corrosion and facilitates a dense and stable passivation film compared to other oxides like Al2O3, thereby improving the corrosion resistance of the coatings. …”
Get full text
Article -
6391
Exploring the potential benefits of areca nut extract in animal production: a review
Published 2025-02-01“…Its remarkable anti-inflammatory and antioxidant potential, along with its outstanding performance in antibacterial, antifungal, and antiviral activities, plays a crucial role in inhibiting various pathogens and protecting cells from oxidative damage. This review aims to comprehensively explore the biological activities of areca nut extract and delve into its practical application potential in enhancing animal production efficiency and promoting sustainable livestock development.The pervasive presence of antibiotic residues—including tetracyclines, sulfonamides, and quinolones—in agricultural products such as meat, milk, and eggs has raised significant concerns due to their extensive use in animal husbandry. …”
Get full text
Article -
6392
Assessment of borehole water quality in Nwadzekudzeku village, Giyani, Limpopo Province, South Africa: Implication for potential human health risks
Published 2025-03-01“…Results and Discussion: The results showed that borehole water had a pH ranging from 6.96 - 7.76, an electrical conductivity (EC) of 132 - 2740 µS.cm−1, total dissolved solids (TDS) of 381 - 1336 mg.L−1, resistivity in the range of 62 - 1030 Ω, salinity from 0.32 - 1.34 ppt and an oxidation–reduction potential (ORP) of 9.20 - 233 mV. …”
Get full text
Article -
6393
Lipopolysaccharide (LPS) Aggravates High Glucose- and Hypoxia/Reoxygenation-Induced Injury through Activating ROS-Dependent NLRP3 Inflammasome-Mediated Pyroptosis in H9C2 Cardiomyo...
Published 2019-01-01“…Diabetes aggravates myocardial ischemia-reperfusion (I/R) injury because of the combination effects of changes in glucose and lipid energy metabolism, oxidative stress, and systemic inflammatory response. …”
Get full text
Article -
6394
Tracking hydrothermal infiltration within light oil reservoirs using organic geochemical proxies in the Shunbei area of Tarim Basin in China
Published 2025-01-01“…C22/C21 TT, indicate that marine shales deposited in a reducing-weakly oxidized environment are major source rocks. Natural gases are associated with oil reservoirs and are mainly generated via the decomposition of kerogen and crude oil. …”
Get full text
Article -
6395
Major facility superfamily sugar transporter protein SsMFSST1 regulates Sporisorium scitamineum mating, pathogenicity, and sugar transport/absorption
Published 2025-02-01“…On YePSA medium, the gene SsMFSST1 does not affect the growth, spore morphology, colony morphology, and oxidative stress ability of the haploid spores of S. scitamineum. …”
Get full text
Article -
6396
Electroporation assisted delivery of Roussin salt porphyrin-based conjugated carbon nanoparticles for sono–X-ray–photodynamic prostate cancer in vitro and in vivo treatment
Published 2025-01-01“…Furthermore, EP@RRBP-CNP is a promising SXPS that, when used in conjunction with SXPDT, can be very effective in in vitro treating PCa-DU-145 (in a dose-dependent manner cell viability declined, an increase in the cells population during the G0/G1-phase indicates that the cell cycle was arrested, and an increase in cell population in the Pre-G, autophagic cell death, as well as necrosis and early and late apoptosis, indicate that cell death was induced) and MNU/testosterone-PCa-induced mice in vivo (induced antiproliferative genes, p53, Bax, TNFalpha, caspase 3,9, repressed antiangiogenic and antiapoptotic genes, VEGF and Bcl2, respectively), successfully slowing the growth of tumors and even killing cancer cells, as well as lowering oxidative stress (MDA), improving the functions of the kidneys (urea, creatinine), liver (ALT, AST), and antioxidants (GPx, GPx, GST, CAT, GSH, TAC). …”
Get full text
Article -
6397
Human Umbilical Cord-Derived Mesenchymal Stem Cell Therapy Ameliorates Nonalcoholic Fatty Liver Disease in Obese Type 2 Diabetic Mice
Published 2019-01-01“…Mechanistically, UC-MSCs were found to regulate lipid metabolism by increasing the expression of fatty acid oxidation-related genes and inhibiting the expression of lipogenesis-related genes, which were associated with the upregulation of the HNF4α-CES2 pathway. …”
Get full text
Article -
6398
Does Sex Matter in Obesity-Induced Periodontal Inflammation in the SS<sup>LepR</sup> Mutant Rats?
Published 2024-12-01“…Plasma thiobarbituric acid reactive substances (TBARs) and monocyte chemoattractant protein-1 (MCP-1), markers of systemic oxidative stress and inflammation, respectively, were significantly elevated in obese SS<sup>LepR</sup> mutant rats vs. lean SS rats, with no sex differences in these parameters in either rat strains. …”
Get full text
Article -
6399
Beverage consumption modifies the risk of type 2 diabetes associated with ambient air pollution exposure
Published 2025-01-01“…Annual average concentrations of fine particulate matter (PM2.5 and PM10) and nitrogen oxides (NO2 and NOX) were estimated to represent the long-term AP exposure using the land use regression model. …”
Get full text
Article -
6400
Search for biocontrol agents among endophytic lipopeptidesynthesizing bacteria <i>Bacillus</i> spp. to protect wheat plants against Greenbug aphid (<i>Schizaphis graminum</i>)
Published 2024-05-01“…Endophytic lipopeptide-synthesizing strains of Bacillus spp. indirectly affected the viability of aphids, the endurance of plants against aphids and triggered ISR in plants, which manifested itself in the regulation of oxidative metabolism and the accumulation of transcripts of the Pr1, Pr2, Pr3, Pr6 and Pr9 genes due to the synthesis of lipopeptides, which was proven using LRF isolated from three strains: B. subtilis 26D, B. subtilis 11VM, and B. thuringiensis B-6066. …”
Get full text
Article