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6361
UV-fs-LA-ICP-MS Analysis of CO2-Rich Fluid Inclusions in a Frozen State: Example from the Dahu Au-Mo Deposit, Xiaoqinling Region, Central China
Published 2018-01-01“…The Dahu ore fluids differ from metamorphic fluids in compositions and most likely represent two separate pulses of spent fluids evolved from an unexposed and oxidized magmatic system. The UV-fs-LA-ICP-MS analysis of fluid inclusions in a frozen state improves the overpressure problem of CO2-rich fluid inclusions during laser ablation. …”
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6362
Study on improving yield and antioxidant enzyme activities in millet by rationing molybdenum and nitrogen
Published 2025-01-01“…The application of appropriate nitrogen and molybdenum fertilizer can improve the growth and development of plants, increase photosynthetic efficiency, regulate active oxygen metabolism in vivo, maintain the oxidation balance required for normal cell growth, enhance the activity of crop antioxidant enzymes and dry matter accumulation, so as to increase crop yield. …”
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6363
CircTTC13 promotes sorafenib resistance in hepatocellular carcinoma through the inhibition of ferroptosis by targeting the miR-513a-5p/SLC7A11 axis
Published 2025-01-01“…Many first-line chemotherapeutic drugs induce ferroptosis, a form of programmed cell death dependent on ferrous iron-mediated oxidative stress, suggesting that drug resistance and ensuing tumor progression may in part stem from reduced ferroptosis. …”
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6364
Multi-Omics Analysis in Mouse Primary Cortical Neurons Reveals Complex Positive and Negative Biological Interactions Between Constituent Compounds of <i>Centella asiatica</i>
Published 2024-12-01“…Urban, family Apiaceae (CAW), improves cognitive function in mouse models of aging and Alzheimer’s disease and affects dendritic arborization, mitochondrial activity, and oxidative stress in mouse primary neurons. Triterpenes (TT) and caffeoylquinic acids (CQA) are constituents associated with these bioactivities of CAW, although little is known about how interactions between these compounds contribute to the plant’s therapeutic benefit. …”
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6365
Exercise-induced anxiety impairs local and systemic inflammatory response and glucose metabolism in C57BL/6J mice
Published 2025-02-01“…Results: Anxiety-like behavior, elevated circulating glucose concentrations, systemic stress and inflammatory responses, together with increased oxidative stress and inflammatory profile of peritoneal macrophages, and macrophage infiltration in white adipose tissue were observed in exercised animals. …”
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6366
Investigating processes influencing simulation of local Arctic wintertime anthropogenic pollution in Fairbanks, Alaska, during ALPACA-2022
Published 2025-01-01“…Simulated concentrations of carbon monoxide (CO), sulfur dioxide (<span class="inline-formula">SO<sub>2</sub></span>), and nitrogen oxides (<span class="inline-formula">NO<sub><i>x</i></sub></span>), including surface and elevated sources, are the highest at the surface under very cold stable conditions. …”
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6367
Enhanced photocatalytic degradation of Rhodamine B using polyaniline-coated XTiO3(X = Co, Ni) nanocomposites
Published 2025-01-01“…Abstract In this study, novel polyaniline-coated perovskite nanocomposites (PANI@CoTiO3 and PANI@NiTiO3) were synthesized using an in situ oxidative polymerization method and evaluated for the photocatalytic degradation of Rhodamine B (RhB) a persistent organic pollutant. …”
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6368
CD38 deficiency leads to a defective short-lived transcriptomic response to chronic graft-versus-host disease induction, involving purinergic signaling-related genes and distinct t...
Published 2025-02-01“…Last, we have shown an intense metabolic reprogramming toward oxidative phosphorylation in PECs and SPC from cGVHD WT mice, which may reflect an increased cellular demand for oxygen consumption, in contrast to PECs and SPC from cGVHD Cd38-/- mice, which showed a short-lived metabolic effect at the transcriptomic level. …”
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6369
Salvia deserti Decne., an endemic and rare subshrub from Arabian desert: antidiabetic and antihyperlipidemic effects of leaf hydroethanolic extracts
Published 2025-02-01“…Moreover, treatment with S. deserti hydroethanolic extract relieved oxidative stress (reduction of MDA and H2O2) and the activity of antioxidant enzymes SOD, CAT and GPx. …”
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6370
Investigating processes influencing simulation of local Arctic wintertime anthropogenic pollution in Fairbanks, Alaska, during ALPACA-2022
Published 2025-01-01“…Simulated concentrations of carbon monoxide (CO), sulfur dioxide (<span class="inline-formula">SO<sub>2</sub></span>), and nitrogen oxides (<span class="inline-formula">NO<sub><i>x</i></sub></span>), including surface and elevated sources, are the highest at the surface under very cold stable conditions. …”
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6371
Limnospira (Cyanobacteria) chemical fingerprint reveals local molecular adaptation
Published 2025-02-01“…Interestingly, these molecular enrichments might represent consequent adaptations to conditions of salinity, light, and oxidative stress in their respective sampling environments. …”
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6372
KMO-driven metabolic reconfiguration and its impact on immune cell infiltration in nasopharyngeal carcinoma: a new avenue for immunotherapy
Published 2025-02-01“…In addition, KMO levels were inversely associated with the upregulation of both oxidative phosphorylation (OXPHOS) and glycolysis pathways within the NPC tumor microenvironment (TME). …”
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6373
Safety and efficacy of oral edible bird’s nest supplementation: Anti-inflammatory and immunomodulatory benefits for Arabian race stallions during exercise
Published 2025-01-01“…Background and Aim: Exercise-induced oxidative stress and inflammation adversely affect the health and performance of athletic horses. …”
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6374
Artificial intelligence analysis of thermal energy for convectively heated ternary nanofluid flow in radiated channel considering viscous dissipations aspects
Published 2025-02-01“…With focus on technological advancements in the field of thermal heat, these studies show great promise of THF in enhancing rate of heat transfer-issues which complete several energy storage systems, cooling techniques in aeronautics as well as electric vehicle operational convenience via thermal layout.A synergetic composition of three distinct nanomaterial oxides of Copper, Iron and Silicon in engine oil, contributes unique thermophysical character in thermal management. …”
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6375
Supplementation with Standardized Green/Black or White Tea Extracts Attenuates Hypertension and Ischemia-Reperfusion-Induced Myocardial Damage in Mice Infused with Angiotensin II
Published 2025-01-01“…In the heart, supplementation with both tea extracts attenuated AngII-induced cardiac hypertrophy and reduced ischemia-reperfusion-induced oxidative stress and apoptosis in myocardial tissue. …”
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6376
Effects of celastrol on the heart and liver galaninergic system expression in a mouse model of Western-type diet-induced obesity and metabolic dysfunction-associated steatotic live...
Published 2025-02-01“…Celastrol influenced the gene expression of galanin receptors: it downregulated Galr1 in the heart and upregulated Galr2 in the liver and Galr3 in the heart ventricles, potentially affecting energy metabolism, oxidative stress, and inflammation. Fatostatin suppressed gene expression of all the detected members of the galaninergic system in the heart ventricles, depicting the role of SREBP in this process.ConclusionThese findings suggest that celastrol may beneficially modulate the galaninergic system under obesity and MASLD-to-MASH progression, indicating its potential as a therapeutic agent for disorders associated with metabolic dysfunction.…”
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6377
Tofogliflozin attenuates renal lipid deposition and inflammation via PPARα upregulation mediated by miR-21a impairment in diet-induced steatohepatitic mice
Published 2024-11-01“…Notably, the expression of PPARα, which has been known to be negatively regulated by miR-21, was significantly increased, leading to enhancing β-oxidation genes, Acox1 and Cpt1 in the Tofo group. …”
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6378
Association between exposure to perfluoroalkyl and polyfluoroalkyl substances with estimated glomerular filtration rate: Mediating role of serum albumin
Published 2025-01-01“…Functional enrichment analysis suggested PFAS impair renal function by affecting lipid metabolism and increasing oxidative stress. Conclusions: PFAS exposure is negatively associated with eGFR and positively associated with the risk of decreased renal function, with albumin playing a partial mediating role.…”
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6379
Machine learning-based plasma metabolomics for improved cirrhosis risk stratification
Published 2025-02-01“…Key metabolites, including branched-chain amino acids (BCAAs), lipids, and markers of oxidative stress, were identified as significant predictors. …”
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6380
Short-Term Activation of Peroxisome Proliferator-Activated Receptors α and γ Induces Tissue-Specific Effects on Lipid Metabolism and Fatty Acid Composition in Male Wistar Rats
Published 2019-01-01“…In heart, PPARα activation leads to overall lower levels of free FAs and specific changes in certain FAs, compared with control. Furthermore, β-oxidation in liver and the enzymatic activities of well-known PPARα targeted genes were higher following PPARα administration. …”
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