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6221
Utilizing bioinformatics and machine learning to identify CXCR4 gene-related therapeutic targets in diabetic foot ulcers
Published 2025-02-01“…Functional enrichment analysis showed that these genes were mainly involved in pathways such as oxidative phosphorylation, phagosome, synaptic vesicle cycle, and pathways of neurodegeneration. …”
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6222
A plant endophytic bacterium Burkholderia seminalis strain 869T2 increases plant growth under salt stress by affecting several phytohormone response pathways
Published 2025-02-01“…Conclusions The plant endophytic bacterium strain B. seminalis 869T2 may affect various phytohormone responses and reduce oxidative stress damage to increase salt and drought stress tolerances of host plants.…”
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6223
A Decontamination Process to Remove Metals and Stabilise Montreal Sewage Sludge
Published 2002-01-01“…To solve this particular problem, the treatment plant authorities are currently evaluating an acidic chemical leaching (sulfuric or hydrochloric acid) process at a pH between 2 and 3, using an oxidizing agent such as ferric chloride or hydrogen peroxide (METIX-AC technology, patent pending; [20]). …”
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6224
Skin Microbiota: Mediator of Interactions Between Metabolic Disorders and Cutaneous Health and Disease
Published 2025-01-01“…For instance, hyperglycemia in T2DM leads to the formation of advanced glycation end products (AGEs), which bind to the receptor for AGEs (RAGE) on keratinocytes and immune cells, promoting oxidative stress and inflammation while facilitating Staphylococcus aureus colonization in atopic dermatitis. …”
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6225
Pharmacological Mechanism of Zuojin Pill for Gastroesophageal Reflux Disease: A Network Pharmacology Study
Published 2022-01-01“…Twelve active components of ZJP were identified to act on 82 target genes associated with GERD, and ZJP might exert an anti-GERD effect through the regulation of BPs such as reactive oxygen species (ROS) metabolism, response to oxidative stress (OS), and ROS, as well as the activation of signaling pathways such as apoptosis, p53 signaling, chemical carcinogenesis-ROS, and HIF-1 signaling pathways. …”
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6226
Optimal calorie restriction threshold: effect of FATmax exercise combined with different proportions of calorie restriction on hypercholesterolemia
Published 2025-01-01“…Background/ObjectivesTo evaluate the impact of maximal fat oxidation intensity exercise combined with calorie restriction intervention on lipid-related parameters in a hypercholesterolemic population, and to determine if an optimal range of calorie restriction exists for effectively enhancing blood lipid profiles.MethodsA 4-week intervention study combined exercise and calorie restriction for 64 patients aged 18–60 with secondary hypercholesterolemia. …”
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6227
Combined effect of exercise and curcumin on inflammation-associated microRNAs and cytokines in old male rats: A promising approach against inflammaging
Published 2025-01-01“…Conclusion: Curcumin and exercise, individually and synergistically in combination, effectively reduced inflammation in aged rats, likely due to decreased oxidative stress and MDA levels mediated by miR-21 and miR-146a downregulation.…”
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6228
Polystyrene nanoplastics promote colitis-associated cancer by disrupting lipid metabolism and inducing DNA damage
Published 2025-01-01“…Experiments in LPS intervened Caco-2 cells showed that exposure to PS-NPs led to lipid peroxidation, oxidative stress, and DNA damage in Caco-2. Exposure to PS-NPs activated the phosphatidylinositol 3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) signaling pathway both in the AOM/DSS mouse model and cellular model. …”
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6229
Guanxinning Tablet Attenuates Coronary Atherosclerosis via Regulating the Gut Microbiota and Their Metabolites in Tibetan Minipigs Induced by a High-Fat Diet
Published 2022-01-01“…We simultaneously detected blood lipid levels, observed ventricular function using ultrasound examination, measured platelet aggregation, and checked changes in inflammatory factors, oxidative stress factors, and vascular endothelial injury-related indexes applying ELISA assays. …”
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6230
The intervention of curcumin on rodent models of hepatic fibrosis: A systematic review and meta-analysis.
Published 2024-01-01“…The outcome indicators included liver cell structure and function related indicators, such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), albumin (ALB), ratio of albumin to globulin (A/G), total bilirubin (TBIL), bax protein, bcl-2 protein and index of liver, as well as the relevant indicators for evaluating the degree of hepatic fibrosis, such as hyaluronic acid (HA), laminin (LN), type I collagen (Collagen I), type III collagen (Collagen III), type III procollagen (PCIII), type III procollagen amino terminal peptide (PIIINP), type IV collagen (IV-C), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), α-Smooth muscle actin (α-SMA), hydroxyproline (HYP), platelet derived factor-BB (PDGF-BB), connective tissue growth factor (CTGF) and transforming growth factor-β1 (TGF-β1), and oxidative stress-related indicators, such as superoxide dismutase (SOD), malondialdehyde (MDA) and glutathione peroxidase (GSH-Px). …”
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6231
The Protective Effect of Mangiferin on Formaldehyde-Induced HT22 Cell Damage and Cognitive Impairment
Published 2023-05-01“…In addition, MGF markedly inhibited FA-induced oxidative damage, including Ca<sup>2+</sup> overload, ROS generation, and mitochondrial dysfunction, all of which are associated with ERS. …”
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6232
Color, Structure, and Thermal Stability of Alginate Films with Raspberry and/or Black Currant Seed Oils
Published 2025-01-01“…The ultraviolet and visible (UV-VIS) spectra of raspberry seed oil (RSO) and black currant seed oil (BCSO) indicated differences in bioactive compounds, such as tocopherols, phenolic compounds, carotenoids, chlorophyll, and oxidative status (amounts of dienes, trienes, and tetraenes) of active components added to alginate films. …”
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6233
Changes in Chemical Composition, Sources, and Health Risk of PM2.5 with Sand Storm at a Small City in North China
Published 2022-05-01“…PM2.5 reconstruction indicated that higher dust of 54.0 µg m−3 and trace element oxides (TEO) of 0.234 µg m−3 were found in the SSP, evidencing their immigration from the sand dust. …”
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6234
Novel green synthesis of silver nanoparticles from empty fruit bunch waste: Biomedical applications and mechanistic insights
Published 2025-01-01“…Reactive oxygen species (ROS) may cause cell membrane rupture and oxidative stress. Antioxidant testing demonstrated concentration-dependent activity across multiple assays: DPPH scavenging reached 81.49 % at 160 µg/ml, ferric-reducing activity was 90.05 % at 150 µg/ml, H₂O₂ scavenging achieved 91.00 % at 80 µg/ml, and NO scavenging reached 83.43 % at 150 µg/ml. …”
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6235
Effect of Zinc Additive and Annealing on Dielectric Characteristics of the PSCCO Compound
Published 2025-01-01“… The ceramic PSCCO (PbSr2Ca2Cu3O) and (PbSr2Ca2Cu2.4Zn0.6O) compounds were prepared using high-purity oxides (x=0 and0.6%) via solid reaction. The samples were then pressed into tablets with 1.5 cm diameter, at 5.4MPa for two minutes and sintered at 850°C for 24 hours. …”
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6236
An engineering model for creeping flame spread over idealized electrical wires in microgravity
Published 2023-03-01“…This assumption is supported by more detailed numerical simulations and the model reduces then to solving the heat transfer equations for both NiCr and LDPE in the pyrolysis region and in the region ahead of the flame front along with a simple degradation model for LDPE, an Oseen approximation of opposed oxidizer flow and an infinitely fast gas-phase chemistry. …”
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6237
Identification of prognostic biomarker of non-small cell lung cancer based on mitochondrial permeability transition-driven necrosis-related genes and determination of anti-tumor ef...
Published 2025-02-01“…Abstract Background Mitochondrial permeability transition (MPT)-driven necrosis (MPTDN) is a non-apoptotic mode of cell death triggered by oxidative stress and cytosolic Ca2+ overload. Recent evidence suggests that activation of MPTND can effectively induce cancer cell death and may represent a novel therapeutic strategy for cancer. …”
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6238
Seasonal Variations and Health Risk Evaluation of Trace Elements in Atmospheric PM<sub>2.5</sub> in Liaocheng, the North China Plain
Published 2025-01-01“…Results from positive matrix factorization suggested that the dust source was only identified in spring, accounting for the largest percentage (37.0%), while secondary oxidation made the most significant contribution (34.6%) in summer, facilitated by higher temperatures and stronger sunshine. …”
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6239
The Impact of Thyme and Rosemary on Prevention of Osteoporosis in Rats
Published 2019-01-01“…Supplementation with thyme and rosemary inhibited significantly the development of bone loss, increased Ca and vitamin D3 in plasma, improved BMD, and also prevented the inflammation and oxidative stress (improved TNF-α, CRP and MDA) compared to the positive control. …”
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6240
Methylsulfonylmethane (MSM) Supplementation in Adult Horses Supports Improved Skeletal Muscle Inflammatory Gene Expression Following Exercise
Published 2025-01-01“…The hypothesis that dietary supplementation with MSM alters the exercise-mediated inflammatory and oxidant response was assessed in unfit adult thoroughbred geldings. …”
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