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6201
Chlamydia trachomatis Growth and Cytokine mRNA Response in a Prostate Cancer Cell Line
Published 2019-01-01“…The possible roles of reactive oxygen species and impaired mitochondrial oxidation in the prostate cancer cell line are discussed as factors promoting the early stages of C. trachomatis growth in CWR-R1 cells.…”
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6202
Behaviour of TiC Particles on the Co50-Based Coatings by Laser Cladding: Morphological Characteristics and Growth Mechanism
Published 2020-01-01“…At 700°C, the wear mechanism is mainly oxidation and fatigue.…”
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6203
A Comparative Analysis of the Antioxidant Profiles Generated by the RoXsta<sup>TM</sup> System for Diverse Biological Fluids Highlights the Powerful Protective Role of Human Semina...
Published 2025-01-01“…Moreover, comparative studies demonstrated that human SP exhibited significantly (<i>p</i> < 0.001) higher levels of antioxidant potential than any other species examined (stallion, bull, dog) and that this intense activity reflected the relative vulnerability of human spermatozoa to peroxide attack. (4) Conclusions: The RoXsta<sup>TM</sup> system provides valuable information on the antioxidant profile of complex biological fluids, supporting its diagnostic role in conditions associated with oxidative stress. Based on the results secured in this study, human semen is identified as a particularly rich source of antioxidants capable of scavenging both hydrogen and organic peroxides, in keeping with the high susceptibility of human spermatozoa to peroxide-mediated damage.…”
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6204
Nanonaringenin and Vitamin E Ameliorate Some Behavioral, Biochemical, and Brain Tissue Alterations Induced by Nicotine in Rats
Published 2021-01-01“…Nanonaringenin (NNG) and vitamin E are antioxidants that are reported to mitigate serious impairments caused by some toxins and oxidants. Thus, we aimed to investigate the efficacy of NNG, vitamin E, and their combinations to ameliorate behavioral, biochemical, and histological alterations induced by nicotine in rats. …”
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6205
Zinc Supplementation Prevented Type 2 Diabetes-Induced Liver Injury Mediated by the Nrf2-MT Antioxidative Pathway
Published 2021-01-01“…This induced preventive effects on conditions caused by type 2 diabetes like oxidative stress, apoptosis, the subsequent hepatic inflammatory response, fibrosis, hypertrophy, and hepatic dysfunction. …”
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6206
Potential Strategies Applied by <i>Metschnikowia bicuspidata</i> to Survive the Immunity of Its Crustacean Hosts
Published 2025-01-01“…Key genes involved in oxidative phosphorylation, fatty acid metabolism, upper glycolysis, and gluconeogenesis were upregulated, and those for β-glucan unmasking, autophagy, and cell polarity were downregulated, in the treatment group. …”
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6207
The BET inhibitor JQ1 targets fat metabolism and counteracts obesity
Published 2025-02-01“…JQ1 administration did not impinge on skeletal muscle metabolism and oxidative capability, as shown by the lack of significant impact on mitochondrial mass and biogenesis. …”
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6208
Extracellular electron shuttles induced transformation and mobilization of Fe/As with the occurrence of biogenic vivianite
Published 2025-01-01“…Microorganisms that utilize organic matter to reduce Fe oxides/hydroxides constitute the primary geochemical processes controlling the formation of high-arsenic (As) groundwater. …”
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6209
Valerenic acid ameliorates amphetamine-related neurotoxicity by improving hypothalamus tyrosine hydroxylase and histamine-N-methyl transferase enzymes
Published 2025-06-01“…Results: METH decreased superoxide dismutase, glutathione peroxidase, catalase, NADPH oxidase, interleukin-10, sucrose preference test, distance traveled test, and center square entries test, ATPase activity and the enzymes tyrosine hydroxylase and histamine-N-methyl transferase but increased malondialdehyde, conjugated dienes, oxidative index, serotonin, dopamine, norepinephrine, γ-aminobutyric acid, tumor necrosis factor-α, interleukin-1β, interleukin-6, nuclear factor kappa B levels, the center square duration test, tail suspension test, and forced swimming test. in the METH-treated animals' brain in contrast to the control group. …”
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6210
Refining and conching alter the volatile composition of dark chocolate — Revealing profile changes in aroma-active volatiles and volatile organic compounds
Published 2025-03-01“…Generally, the number of compounds detected, and the FD factors determined decreased along the processing steps, whereas FD factors of aldehydes partially increased as these are generated, inter alia, by lipid oxidation. The influence of processing was likewise mirrored in the VOC profile where conching in particular resulted in decreased VOC intensities. …”
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6211
siRNA-mediated inhibition of hTERT enhances the effects of curcumin in promoting cell death in precursor-B acute lymphoblastic leukemia cells: an in silico and in vitro study
Published 2025-01-01“…Cell viability and proliferation were assessed via MTT and BrdU assays at 24- and 48-hour intervals post-treatment. Ferroptotic and oxidative markers were quantified using commercial assays, while cell death parameters and gene expression were evaluated through flow cytometry and qRT-PCR analyses. …”
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6212
LC-MS Analysis, 15-Lipoxygenase Inhibition, Cytotoxicity, and Genotoxicity of Dissotis multiflora (Sm) Triana (Melastomataceae) and Paullinia pinnata Linn (Sapindaceae)
Published 2020-01-01“…Phytochemical screening was carried out using the LC-MS procedure. The ferrous oxidation-xylenol orange (FOX) assay was used to determine the 15-lipoxygenase (15-LOX) inhibitory activity of the plant samples. …”
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6213
Estimation of cytoprotective effect of bismuth tripotassium dicitrate on gastric mucosa at <i>H. pylori</i> eradication and long-term drug intake
Published 2014-12-01“…To identify cellular «target» of bismuth tripotassium dicitrate (De-nol) therapy – DNA protection of generative zone cells of stomach mucosa (SM) from damages by oxidative burst products in neutrophilic leukocytes at continued intake of the drug for 4 wks after the ending of eradication therapy.Material and methods. …”
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6214
Investigation of Machinability Characteristics of EDMed Inconel 825 Alloy under Multidimensional Parametric Modeling by Using Holistic Grey-PCA Statistical Models
Published 2022-01-01“…., the rich strength, hardness, reliability, high resistance against corrosion and oxidation, and high toughness and refractoriness. Recently, the researchers ascertained the comprehensive applications of these difficult to machine materials in the domain of automotive, aeronautical, nuclear industries etc. …”
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6215
PDE4B promotes ferroptosis in nucleus pulposus cells and is involved in intervertebral disc degeneration
Published 2025-02-01“…Meanwhile, the level of cytokine and oxidative stress were upregulated. Ferroptosis inhibitor Fer-1 or Nrf2 activator dimethyl fumarate (DMF) suppressed the effect of PDE4B-OE, while ferroptosis inducer elastin enhanced the effect of PDE4B-OE. …”
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6216
Enhancing salinity tolerance in cultivated rice through introgression of African rice genes and application of moringa leaf extract
Published 2025-02-01“…MLE treatment mitigated the above salinity-induced adverse effects in both cultivars via reducing the salt-induced oxidative stress through the induction of non-enzymic (total phenols, and flavonoids) and enzymic antioxidants including ascorbate peroxidase, catalase, peroxidase, and polyphenol oxidase in both cultivars. …”
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6217
In Vitro Biological and GC-MS Analysis of Whole Plant Calotropis procera
Published 2024-01-01“…MTT assay, antileishmanial bioassay, microplate Alamar Blue assay, agar tube dilution method, oxidative burst assay using chemiluminescence technique, B-hatching techniques, and triple quadrupole acquisition method MS parameters were the methods used for anticancer, antileishmanial, antibacterial, antifungal, anti-inflammatory, brine shrimp lethality assay, and gas chromatography-mass spectrometry. …”
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6218
An Injectable Hydrogel Bioimplant Loaded with Engineered Exosomes and Triple Anti-Tuberculosis Drugs with Potential for Treating Bone and Joint Tuberculosis
Published 2025-01-01“…This study aimed to develop a bioimplantable scaffold with osteoinductive and antituberculosis characteristics to treat BJTB.Methods: This scaffold is built on oxidized hyaluronic acid and carboxymethyl chitosan hydrogel mixed with hydroxyapatite as a bone tissue engineered material. …”
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6219
Beneficial Effects of <i>In Vitro</i> Reconstructed Human Gut Microbiota by Ginseng Extract Fermentation on Intestinal Cell Lines
Published 2025-01-01“…Oxidative stress caused by reactive oxygen species (ROS) affects the aging process and increases the likelihood of several diseases. …”
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6220
The feasibility study of natural pigments as food colorants and seasonings pigments safety on dried tofu coloring
Published 2018-09-01“…In addition, researches showed that chemical soy sauce produces a trace of methylglyoxal (MGO) in the manufacturing process, which is related to diseases such as oxidative stress, diabetes, and cognitive deterioration. …”
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