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6181
Insight into the role of antioxidant in microbial lignin degradation: Ascorbic acid as a fortifier of lignin-degrading enzymes
Published 2025-02-01“…Proteomics analysis suggested that the enhancement in enzyme activity was more likely to attributed to the reinforcement of AA on oxidative protein folding and transportation, rather than changes in enzyme expression. …”
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6182
MCU complex: Exploring emerging targets and mechanisms of mitochondrial physiology and pathology
Published 2025-02-01“…They regulate processes, such as mitochondrial Ca2+ (mCa2+) uptake, mitochondrial adenosine triphosphate (ATP) production, calcium dynamics, oxidative stress (OS), and cell death. Regulation makes it a potential target for treating diseases, especially cardiovascular diseases, neurodegenerative diseases, inflammatory diseases, metabolic diseases, and tumors.…”
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6183
Elucidating stearoyl metabolism and NCOA4-mediated ferroptosis in gastric cancer liver metastasis through multi-omics single-cell integrative mendelian analysis: advancing personal...
Published 2025-01-01“…Furthermore, the LMGC is integral to cellular processes related to oxidative stress and lipid metabolism, both of which are significant factors in the context of ferroptosis. …”
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6184
Phenolic and amino acid profiles, and antioxidant properties of third generation snack foods adding Citrus mitis by-products and milk powder: impact of extrusion processing and mic...
Published 2025-02-01“…Total flavonoid content (TFC), hydroxyl radical scavenging activity (HRSA), and inhibition of human LDL oxidation (ILDLox) decreased in PS2 regarding PS1. …”
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6185
Effect of Dietary Supplementation of <i>Durvillaea Antarctica</i> Meal on Production and Meat Quality Traits of Lambs
Published 2025-01-01“…However, changes were observed in meat quality traits, including increased redness and reduced luminosity in the loin for the high inclusion treatment, in addition to slight alterations in pH and lower lipid oxidation in lambs’ meat fed <i>Durvillaea antarctica</i>. …”
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6186
Single-cell analyses of intestinal epithelium reveal the dysregulation of gut immune microenvironment in systemic lupus erythematosus
Published 2025-01-01“…Moreover, scRNA-seq revealed significantly decreased intestinal TCRγδ T cells (γδT) associated with reduced aryl-hydrocarbon receptor repressor (AHRR) expression and subsequent oxidative stress and ferroptosis in Lpr mice. Antioxidant selenium effectively reversed the loss of γδT in Lpr mice, improved the gut barrier, and alleviated lupus symptoms. …”
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6187
Antioxidant and Laxative Effects of Methanol Extracts of Green Pine Cones (<i>Pinus densiflora</i>) in Sprague-Dawley Rats with Loperamide-Induced Constipation
Published 2024-12-01“…Oxidative stress is the key cause of the etiopathogenesis of several diseases associated with constipation. …”
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6188
Peroxisome Proliferator-Activated Receptor-γ Antagonizes LOX-1-Mediated Endothelial Injury by Transcriptional Activation of miR-590-5p
Published 2019-01-01“…Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is one of the major receptors expressed on the endothelium of arterial wall with a key role in endothelial dysfunction and the development of atherosclerosis. …”
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6189
Soluble Receptor for Advanced Glycation End Products: A Protective Molecule against Intramyocardial Lipid Accumulation in Obese Zucker Rats?
Published 2019-01-01“…Genes promoting fatty acid transport, activation, and oxidation in mitochondria/peroxisomes were upregulated in OB hearts. …”
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6190
Neuroimaging stratification reveals the striatal vulnerability to stress as a risk for schizophrenia
Published 2025-01-01“…This mediation was associated with the genes enriched in both glutamatergic synapses and response to oxidative stress. The stratified association between the striatum and stress highlights the differential vulnerability to stress, contributing to the complexity of the gene-by-environment etiology of schizophrenia.…”
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6191
Phthalates esters disrupt demersal fish behavior: Unveiling the brain-gut axis impact
Published 2025-01-01“…This accumulation led to oxidative damage, inflammatory responses, and neurodegenerative changes in the optic tectum, resulting in cholinergic system dysfunction. …”
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6192
Gross soil N transformations and microbial communities in Luxembourg beech forest (Fagus sylvatica L.) soils along a pH gradient
Published 2025-02-01“…Autotrophic nitrification also increased with pH, corresponding to elevated ammonium supply from gross mineralization and higher abundances of ammonia-oxidizers. Heterotrophic nitrification was much lower than autotrophic nitrification in calcareous soils but equally important in acidic soils. …”
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6193
Duodenal Organoids From Metabolic Dysfunction-Associated Steatohepatitis Patients Exhibit Absorptive and Barrier Alterations
Published 2025-01-01“…MDEOs displayed altered digestive potential associated with reduced mature absorptive cell fate, but they retained their lipid metabolic capacity, possibly mediated by lipid oxidation in stem/progenitor cells. Additionally, MDEOs misexpressed components of tight and adherens junctions and desmosomes compared to controls. …”
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6194
Does hydrogen-rich water mitigate MP toxicity in rainbow trout (Oncorhyncus mykiss)? Monitoring with hematology, DNA damage, and apoptosis via ROS/GSH/MDA pathway
Published 2023-06-01“…In this direction, the following were determined: PP+PE chronic toxicity in aquatic organisms, the toxicity mechanism and the effect of HRW as a possible treatment method in blood tissue; with hematological indices ([RBC count [RBC], leukocyte count [WBC], hemoglobin value [Hb], hematocrit ratio [Hct], platelet count [PLT], hemoglobin count per erythrocyte [MCHC], mean hemoglobin amount per erythrocyte [MCH] and mean erythrocyte volume [MCV]) in other tissues (liver, gill and brain tissue) oxidative stress response (catalase [CAT]), glutathione peroxidase (GPx), glutathione reductase (GR), superoxide dismutase (SOD), glutathione (GSH), reactive oxygen products (ROS), malondialdehyde ([MDA] levels), DNA damage (8-OHdG: 8-Hydroxy-2-Deoxyguanosine), and the apoptosis (caspase 3) levels were investigated. …”
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6195
Impact of Arbuscular Mycorrhizal Symbiosis on Photosynthetic, Antioxidant Enzyme, and Water Flux Parameters in Salt-Stressed Chickpea (<i>Cicer arietinum</i>) Plants
Published 2025-01-01“…AMF (arbuscular mycorrhizal fungus) reduces salt’s detrimental effects on plants’ growth by bolstering the plant’s antioxidant defense system, effectively reducing the damage caused by oxidative stress. In this study, the impact of AMF on salinity stress alleviation in chickpea was investigated in pot-grown experiments. …”
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6196
Associations and potential epigenetic changes between air pollution and osteoarthritis risk and survival: Insights from a prospective cohort study
Published 2025-01-01“…Methods: We conducted a prospective cohort study in the UK Biobank, estimating exposure levels of particulate matter (PM2.5, PM10, PM2.5–10), nitrogen oxides (NO2, NOx), and air pollutants exposure score (APES). …”
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6197
Toxicological effects of the environmental pollutant perfluoronanoic acid on the ground-dwelling arthropod Solenopsis invicta
Published 2025-01-01“…Elevated superoxide dismutase (SOD) and catalase (CAT) activities at higher PFNA concentrations indicated oxidative stress in RIFAs. Collectively, these findings demonstrate PFNA's concentration-dependent toxic and repellent effects on RIFAs, emphasizing the need for further research on PFNA toxicity in ground-dwelling arthropods and the potential of RIFAs as a bioassay species for pollutant assessment.…”
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6198
Characterization of meat quality, storage stability, flavor-related compounds, and their relationship in Korean Woorimatdag No. 2 chicken breast meat during cold storage
Published 2025-01-01“…In both groups, aerobic plate counts, volatile basic nitrogen, and lipid oxidation levels increased, whereas creatine and dipeptide levels gradually decreased during storage. …”
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6199
The Role of Duodenogastroesophageal Reflux in the Progression of Gastroesophageal Reflux Disease: From Esophagitis to Adenocarcinoma
Published 2024-08-01“…The presence of hydrophobic bile acids, namely deoxycholic acid (DCA), is associated with oxidative DNA damage in lesions of intestinal-type columnar cell metaplasia. …”
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6200
Investigation of Mechanical and Tribological Characteristics of Medical Grade Ti6al4v Titanium Alloy in Addition with Corrosion Study for Wire EDM Process
Published 2022-01-01“…Metals used in biomedical applications are frequently coated to prevent oxidation and metallic ion release, both of which can be harmful due to toxic effects. …”
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