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  1. 6181

    Insight into the role of antioxidant in microbial lignin degradation: Ascorbic acid as a fortifier of lignin-degrading enzymes by Aipeng Li, Weimin Wang, Shuqi Guo, Changzhi Li, Xinying Wang, Qiang Fei

    Published 2025-02-01
    “…Proteomics analysis suggested that the enhancement in enzyme activity was more likely to attributed to the reinforcement of AA on oxidative protein folding and transportation, rather than changes in enzyme expression. …”
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  2. 6182

    MCU complex: Exploring emerging targets and mechanisms of mitochondrial physiology and pathology by Jin Wang, Jinyong Jiang, Haoliang Hu, Linxi Chen

    Published 2025-02-01
    “…They regulate processes, such as mitochondrial Ca2+ (mCa2+) uptake, mitochondrial adenosine triphosphate (ATP) production, calcium dynamics, oxidative stress (OS), and cell death. Regulation makes it a potential target for treating diseases, especially cardiovascular diseases, neurodegenerative diseases, inflammatory diseases, metabolic diseases, and tumors.…”
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  3. 6183

    Elucidating stearoyl metabolism and NCOA4-mediated ferroptosis in gastric cancer liver metastasis through multi-omics single-cell integrative mendelian analysis: advancing personal... by Zhongqiu Yang, Yuquan Chen, Yaping Miao, Haisheng Yan, Kexin Chen, Yaoqin Xu, Lanqian Su, Lanyue Zhang, Yalan Yan, Hao Chi, Jin Fu, Lexin Wang

    Published 2025-01-01
    “…Furthermore, the LMGC is integral to cellular processes related to oxidative stress and lipid metabolism, both of which are significant factors in the context of ferroptosis. …”
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  4. 6184
  5. 6185

    Effect of Dietary Supplementation of <i>Durvillaea Antarctica</i> Meal on Production and Meat Quality Traits of Lambs by John Quiñones, Rodrigo Huaquipán, Rommy Díaz, Isabela Pérez Núñez, Matías Cortes, Ailín Martínez, Gastón Sepúlveda, Lidiana Velaszquez, David Cancino, Erwin Paz, Néstor Sepulveda

    Published 2025-01-01
    “…However, changes were observed in meat quality traits, including increased redness and reduced luminosity in the loin for the high inclusion treatment, in addition to slight alterations in pH and lower lipid oxidation in lambs’ meat fed <i>Durvillaea antarctica</i>. …”
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  6. 6186

    Single-cell analyses of intestinal epithelium reveal the dysregulation of gut immune microenvironment in systemic lupus erythematosus by Qiaolin Wang, Yutong Wu, Lianlian Ouyang, Xiaoli Min, Meiling Zheng, Lingyu Gao, Xiaoyun Chen, Zhi Hu, Shuang Yang, Wenjuan Jiang, Sujie Jia, Qianjin Lu, Ming Zhao

    Published 2025-01-01
    “…Moreover, scRNA-seq revealed significantly decreased intestinal TCRγδ T cells (γδT) associated with reduced aryl-hydrocarbon receptor repressor (AHRR) expression and subsequent oxidative stress and ferroptosis in Lpr mice. Antioxidant selenium effectively reversed the loss of γδT in Lpr mice, improved the gut barrier, and alleviated lupus symptoms. …”
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  7. 6187
  8. 6188

    Peroxisome Proliferator-Activated Receptor-γ Antagonizes LOX-1-Mediated Endothelial Injury by Transcriptional Activation of miR-590-5p by Lei Xu, Gang Zhao, Hong Zhu, Shijun Wang, Aijun Sun, Yunzeng Zou, Junbo Ge

    Published 2019-01-01
    “…Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is one of the major receptors expressed on the endothelium of arterial wall with a key role in endothelial dysfunction and the development of atherosclerosis. …”
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  9. 6189
  10. 6190

    Neuroimaging stratification reveals the striatal vulnerability to stress as a risk for schizophrenia by Xiaoqian Ma, Nana Feng, Lena Palaniyappan, Luolong Cao, Zixin Gu, Jujiao Kang, Liu Yuan, Lijun Ouyang, Yujue Wang, Chunwang Li, Ke Jin, Xiaogang Chen, Jianfeng Feng, Ying He, Qiang Luo

    Published 2025-01-01
    “…This mediation was associated with the genes enriched in both glutamatergic synapses and response to oxidative stress. The stratified association between the striatum and stress highlights the differential vulnerability to stress, contributing to the complexity of the gene-by-environment etiology of schizophrenia.…”
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  11. 6191

    Phthalates esters disrupt demersal fish behavior: Unveiling the brain-gut axis impact by Liuqingqing Liu, Xinyao Li, Xianxiang Luo, Xiao Wang, Linjia Liu, Zixi Yuan, Cuizhu Sun, Hao Zheng, Elvis Genbo Xu, Fengmin Li

    Published 2025-01-01
    “…This accumulation led to oxidative damage, inflammatory responses, and neurodegenerative changes in the optic tectum, resulting in cholinergic system dysfunction. …”
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  12. 6192

    Gross soil N transformations and microbial communities in Luxembourg beech forest (Fagus sylvatica L.) soils along a pH gradient by Mengru Jia, Annemieke Kooijman, Roland Bol, Wim W. Wessel, Kathrin Hassler, Albert Tietema

    Published 2025-02-01
    “…Autotrophic nitrification also increased with pH, corresponding to elevated ammonium supply from gross mineralization and higher abundances of ammonia-oxidizers. Heterotrophic nitrification was much lower than autotrophic nitrification in calcareous soils but equally important in acidic soils. …”
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  13. 6193

    Duodenal Organoids From Metabolic Dysfunction-Associated Steatohepatitis Patients Exhibit Absorptive and Barrier Alterations by Alia Hadefi, Morgane Leprovots, Gilles Dinsart, Maryam Marefati, Marjorie Vermeersch, Daniel Monteyne, David Pérez-Morga, Anne Lefort, Frédérick Libert, Laurine Verset, Claire Liefferinckx, Christophe Moreno, Jacques Devière, Eric Trépo, Marie-Isabelle Garcia

    Published 2025-01-01
    “…MDEOs displayed altered digestive potential associated with reduced mature absorptive cell fate, but they retained their lipid metabolic capacity, possibly mediated by lipid oxidation in stem/progenitor cells. Additionally, MDEOs misexpressed components of tight and adherens junctions and desmosomes compared to controls. …”
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  14. 6194

    Does hydrogen-rich water mitigate MP toxicity in rainbow trout (Oncorhyncus mykiss)? Monitoring with hematology, DNA damage, and apoptosis via ROS/GSH/MDA pathway by Atamanalp Muhammed, Kırıcı Muammer, Köktürk Mine, Kırıcı Mahinur, Alwazeer Duried, Kocaman Esat Mahmut, Ucar Arzu, Parlak Veysel, Özcan Sinan, Alak Gonca

    Published 2023-06-01
    “…In this direction, the following were determined: PP+PE chronic toxicity in aquatic organisms, the toxicity mechanism and the effect of HRW as a possible treatment method in blood tissue; with hematological indices ([RBC count [RBC], leukocyte count [WBC], hemoglobin value [Hb], hematocrit ratio [Hct], platelet count [PLT], hemoglobin count per erythrocyte [MCHC], mean hemoglobin amount per erythrocyte [MCH] and mean erythrocyte volume [MCV]) in other tissues (liver, gill and brain tissue) oxidative stress response (catalase [CAT]), glutathione peroxidase (GPx), glutathione reductase (GR), superoxide dismutase (SOD), glutathione (GSH), reactive oxygen products (ROS), malondialdehyde ([MDA] levels), DNA damage (8-OHdG: 8-Hydroxy-2-Deoxyguanosine), and the apoptosis (caspase 3) levels were investigated. …”
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  15. 6195

    Impact of Arbuscular Mycorrhizal Symbiosis on Photosynthetic, Antioxidant Enzyme, and Water Flux Parameters in Salt-Stressed Chickpea (<i>Cicer arietinum</i>) Plants by Pooja Pooja, Sarita Devi, Sridevi Tallapragada, Yogesh K. Ahlawat, Nisha Sharma, Pankaj Kasnia, Nita Lakra, Rosa Porcel, Jose M. Mulet, Khalid M. Elhindi

    Published 2025-01-01
    “…AMF (arbuscular mycorrhizal fungus) reduces salt’s detrimental effects on plants’ growth by bolstering the plant’s antioxidant defense system, effectively reducing the damage caused by oxidative stress. In this study, the impact of AMF on salinity stress alleviation in chickpea was investigated in pot-grown experiments. …”
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  16. 6196

    Associations and potential epigenetic changes between air pollution and osteoarthritis risk and survival: Insights from a prospective cohort study by Jing Qian, Jiahao Zhu, Yifan Wang, Ruoqi Dai, Jingyou Miao, Ye Yang, Wenxia Zhao, Jing Wang, Lilu Ding, Dan Zhou, Min Yu, Yingjun Li

    Published 2025-01-01
    “…Methods: We conducted a prospective cohort study in the UK Biobank, estimating exposure levels of particulate matter (PM2.5, PM10, PM2.5–10), nitrogen oxides (NO2, NOx), and air pollutants exposure score (APES). …”
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  17. 6197

    Toxicological effects of the environmental pollutant perfluoronanoic acid on the ground-dwelling arthropod Solenopsis invicta by Wenxuan Wang, Mingrong Liang, Yangting Ou, Xiangrui Wang, Yunbo Song, Huimei Chen, Jingxin Hong, Yuling Liang, Yongyue Lu

    Published 2025-01-01
    “…Elevated superoxide dismutase (SOD) and catalase (CAT) activities at higher PFNA concentrations indicated oxidative stress in RIFAs. Collectively, these findings demonstrate PFNA's concentration-dependent toxic and repellent effects on RIFAs, emphasizing the need for further research on PFNA toxicity in ground-dwelling arthropods and the potential of RIFAs as a bioassay species for pollutant assessment.…”
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  18. 6198

    Characterization of meat quality, storage stability, flavor-related compounds, and their relationship in Korean Woorimatdag No. 2 chicken breast meat during cold storage by Yousung Jung, Soomin Oh, Sangrok Lee, Hee-Jeong Lee, Hyo-Jun Choo, Cheorun Jo, Ki-Chang Nam, Jun-Heon Lee, Aera Jang

    Published 2025-01-01
    “…In both groups, aerobic plate counts, volatile basic nitrogen, and lipid oxidation levels increased, whereas creatine and dipeptide levels gradually decreased during storage. …”
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  19. 6199

    The Role of Duodenogastroesophageal Reflux in the Progression of Gastroesophageal Reflux Disease: From Esophagitis to Adenocarcinoma by O. A. Storonova, A. V. Paraskevova, A. A. Makushina

    Published 2024-08-01
    “…The presence of hydrophobic bile acids, namely deoxycholic acid (DCA), is associated with oxidative DNA damage in lesions of intestinal-type columnar cell metaplasia. …”
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  20. 6200

    Investigation of Mechanical and Tribological Characteristics of Medical Grade Ti6al4v Titanium Alloy in Addition with Corrosion Study for Wire EDM Process by S. Prakash, C. S. Abdul Favas, I. Ameeth Basha, R. Venkatesh, M. Prabhahar, V. P. Durairaj, K. Gomathi, Haiter Lenin

    Published 2022-01-01
    “…Metals used in biomedical applications are frequently coated to prevent oxidation and metallic ion release, both of which can be harmful due to toxic effects. …”
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