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1941
Translational regulation of PKD1 by evolutionarily conserved upstream open reading frames
Published 2025-12-01“…The 5´ UTR and uORFs do not modulate downstream protein output under endoplasmic reticulum stress and oxidative stress conditions. Some of uORF-perturbing variants in the SNP database are predicted to affect gene translation. …”
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1942
The Role of Epoxyeicosatrienoic Acids in Diabetes Mellitus-Induced Impaired Vascular Relaxation of Aortic Rings in Ovariectomized Sprague-Dawley Rats
Published 2019-01-01“…Aortic tissue mRNA expression of eNOS, iNOS, COX-1, COX-2, thromboxane synthase 1 (TBXAS1), CYP4A1, CYP4A3, and CYP2J3, as well as plasma oxidative stress, was measured. Results. AChIR did not differ in non-OVX-DM rats compared to non-OVX-CTR ones. …”
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1943
Effect of Centella asiatica Leaf Extract on the Dietary Supplementation in Transgenic Drosophila Model of Parkinson’s Disease
Published 2014-01-01“…The exposure of extract to PD model flies results in a significant delay in the loss of climbing ability and activity pattern and reduced the oxidative stress (P<0.05) in the brains of PD flies as compared to untreated PD flies. …”
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1944
Structure, Immune and Anti-aging Activities of Capsular Polysaccharide Produced by Lactobacillus plantarum W1
Published 2025-02-01“…The average lifespan of nematodes under normal, oxidative stress and heat shock conditions reached its maximum at 125 μg/mL, with lifespan extension rates of 21.05%±0.21%, 42.86%±0.27% and 50.00%±0.27%, respectively. …”
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1945
Periodontal Disease and Obstructive Sleep Apnea: Shared Mechanisms, Clinical Implications, and Future Research Directions
Published 2025-01-01“…Both conditions are characterized by chronic inflammation and oxidative stress, which independently contribute to cardiovascular disease, diabetes, and other systemic disorders. …”
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1946
Effect of multiorgan abdominal ischemic preconditioning on experimental kidney transplantation
Published 2024-12-01“…Similar results were observed for tumor necrosis factor-α, interleukin-6 and CXCL10, as well as indicators of oxidative stress, with statistically significant levels for CXCL10 [0,295 ± 0,0074 arbitrary units (AU) CT and 0,0057 ± 0,0065 AU MAIP] and TBARS (2,93 ± 0,08 nmol/μg CT; and 2,49 ± 0,23 nmol/μg MAIP; p 0.05). …”
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1947
Comparative transcriptome analysis reveals the key role of photosynthetic traits in the formation of differences in photothermal sensitivity in tobacco
Published 2025-01-01“…This effectively mitigated the harmful effects of oxidative stress, helping to maintain normal photosynthetic function. …”
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1948
Relationship between Corneal Temperature and Intraocular Pressure in Healthy Individuals: A Clinical Thermographic Analysis
Published 2016-01-01“…It can be speculated that both oxidative stress and sympathetic nerve fiber stimulation by temperature oscillations may affect the regulation of AH vortex flow and turnover, thus influencing IOP values.…”
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1949
Effects of ibuprofen and microplastics on movement, growth and reproduction in the freshwater snail Physella acuta
Published 2025-01-01“…Our results suggest that ibuprofen affects growth and the total number of eggs, likely due to oxidative stress, neurotoxicity, or disrupted hormonal pathways. …”
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1950
The Protective Effects of Melatonin on Hainan Black Goats Under Heat Stress: Understanding Its Actions and Mechanisms
Published 2025-01-01“…Our mechanistic exploration revealed that melatonin treatment not only reduced the oxidative stress and inflammatory reaction caused by heat stress but also improved goats’ metabolic capacity, promoting their growth and development. …”
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1951
Deoxycholic Acid as a Modifier of the Permeation of Gliclazide through the Blood Brain Barrier of a Rat
Published 2013-01-01“…Major problem for diabetic patients represents damage of blood vessels and the oxidative stress of the brain cells due to increased concentration of free radicals and poor nutrition of brain cells. …”
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1952
Additive Effects of Glutathione in Improving Antibiotic Efficacy in HIV–<i>M.tb</i> Co-Infection in the Central Nervous System: A Systematic Review
Published 2025-01-01“…Results: Preclinical studies showed that GSH improves macrophage antimicrobial function, reduces oxidative stress, and limits <i>Mycobacterium tuberculosis</i> (<i>M.tb</i>) growth. …”
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1953
The effects of chicken hydrolyzed proteins in extruded diets on plasma and fecal metabolic profiles in adult dogs
Published 2024-12-01“…Higher plasma pipecolate and glutamate, higher fecal spermidine and indole propionate, and lower phenol-derived products in both plasma and feces were found in CLHd group than CONd (q < 0.05), indicating lower oxidative stress and inflammation levels. The main difference in lipid metabolism between CHd and CONd was the bile acid metabolism, showing lower circulating bile acid, lower unconjugated bile acid excretion and higher taurine-conjugated bile acid excretion in the CHd group (q < 0.05). …”
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1954
Feasibility and Safety of Perilla Seed Oil as an Additional Antioxidative Therapy in Patients with Mild to Moderate Dementia
Published 2018-01-01“…Dementia is a broad-spectrum terminology for a degenerate in cognitive function severe enough to intervene in activities of daily living. Oxidative stress plays a major role in the neurodegenerative cascade, leading to the irreversible mechanism in dementia. …”
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1955
Preparation and Characterization of Auricularia cornea Ehrenb Polysaccharide-Zn Complex and Its Hypoglycemic Activity through Regulating Insulin Resistance in HepG2 Cells
Published 2021-01-01“…Therefore, it was speculated that the hypoglycemic effect of Auricularia cornea Ehrenb polysaccharide combined with zinc was related to the alleviation of liver cell damage caused by oxidative stress and the improvement of glucose metabolism of IR-HepG2 cells. …”
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1956
Inulin Reduces Kidney Damage in Type 2 Diabetic Mice by Decreasing Inflammation and Serum Metabolomics
Published 2024-01-01“…The administration of inulin not only ameliorated renal injury but also resulted in a reduction in the mRNA expressions of inflammatory factors in the spleen and serum oxidative stress levels, when compared to the DM group. …”
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1957
Efficacy of 2‐Mercaptoethane Sulfonate Sodium (MESNA) in the Prevention of Pancreatitis After Endoscopic Retrograde Cholangiopancreatography: A Randomized Open Label Trial
Published 2025-01-01“…ABSTRACT Background and Aim Oxidative stress has been considered a factor in the development of post‐endoscopic retrograde cholangiopancreatography pancreatitis (PEP). …”
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1958
Bioactive Anti-Aging Substances: Geroprotectors
Published 2024-05-01“…These biologically active substances prevent oxidative stress, accumulation of lipofuscin, and senescent cells. …”
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1959
5-HT Drives Mortality in Sepsis Induced by Cecal Ligation and Puncture in Mice
Published 2017-01-01“…In conclusion, 5-HT drives mortality and exacerbates organ dysfunction by promoting serum cytokines and bacterial loads as well as facilitating oxidative stress in the process of sepsis.…”
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1960
Essential oils modulate virulence phenotypes in a multidrug-resistant pyomelanogenic Pseudomonas aeruginosa clinical isolate
Published 2025-01-01“…Abstract Pyomelanogenic P. aeruginosa, frequently isolated from patients with urinary tract infections and cystic fibrosis, possesses the ability to withstand oxidative stress, contributing to virulence and resulting in persistent infections. …”
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