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1861
Antioxidant Properties of Berberis aetnensis C. Presl (Berberidaceae) Roots Extract and Protective Effects on Astroglial Cell Cultures
Published 2014-01-01“…Presl may be one of the mechanisms by which the extract is effective against health disorders associated to oxidative stress.…”
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1862
Ginkgolide B Protects Cardiomyocytes from Angiotensin II-Induced Hypertrophy via Regulation of Autophagy through SIRT1-FoxO1
Published 2021-01-01“…We then showed that GB attenuated Ang II-induced oxidative stress and reduction in SIRT1 and FoxO1 protein expression. …”
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1863
UPLC-MS metabolite profiling and antioxidant activity of Sanghuangporus sanghuang extract
Published 2025-01-01“…It contains potential natural antioxidant that could be used as a lead contender in the development of antioxidant medicines for the treatment of a wide range of oxidative stress-related illnesses.…”
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1864
San-Huang-Yi-Shen Capsule Ameliorates Diabetic Kidney Disease through Inducing PINK1/Parkin-Mediated Mitophagy and Inhibiting the Activation of NLRP3 Signaling Pathway
Published 2022-01-01“…Our result showed that SHYS could alleviate DKD through reducing the body weight loss, decreasing the levels of fasting blood glucose (FBG), and improving the renal function, insulin resistance (IR), and inhibiting inflammatory response and oxidative stress in the kidney. Moreover, transmission electron microscopy showed SHYS treatment improved the morphology of mitochondria in the kidney. …”
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1865
Effects of Chlorogenic Acid on In Vitro Maturation and Vitrification Cryopreservation of Sheep Oocytes
Published 2025-01-01“…In order to improve the low maturation rate and poor vitrification freezing effect of sheep oocytes caused by oxidative stress. In this study, oocytes from 200 2–3-year-old Kazakh sheep were collected, and different concentrations of CGA were added to the maturation medium and vitrification freezing solution to study the effects of CGA on the maturation rate, cleavage rate, blastocyst rate, reactive oxygen species (ROS) and glutathione (GSH) levels, mitochondrial membrane potential, and the expression levels of oxidation and apoptosis-related genes in sheep oocytes. …”
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1866
Characterization and evaluation of antioxidant properties of leaf extracts from Rhododendron arboreum
Published 2025-01-01“…Phytochemicals have been known to suppress the microbial activity and oxidative stress, which indicates the significance of plant material as anti-microbial and antioxidant agent. …”
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1867
Red dragon fruit (Hylocereus polyrhizus), a superfruit rich in betacyanins pigments with antioxidative potential for hepatoprotection: A review
Published 2025-06-01“…Yet, RDF is a vital alternative source of betacyanins that can be developed into functional food products to take part in functional food security for the prevention of non-communicable diseases caused by oxidative stress to address the goals of the United Nations 2030 Agenda for Sustainable Development.…”
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1868
Regulatory roles of eugenol in paraquat-altered SNCA/LZTS3/MAPT in the cerebellum of Wistar rats
Published 2025-01-01“…Antioxidants were reduced considerably, and oxidative stress markers were increased significantly, which could have caused increased protein fibrillation and reduced limb functionality. …”
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1869
Molecular Age-Related Changes in the Anterior Segment of the Eye
Published 2017-01-01“…Among the principal causes of age-dependent alterations in the anterior segment of the eye, we found the mutation of the TGF-β gene and loss of autophagy in addition to oxidative stress, which contributes to the pathogenesis of degenerative diseases. …”
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1870
NLRP3 Inflammasome: Activation and Regulation in Age-Related Macular Degeneration
Published 2015-01-01“…The major pathways associated with its pathogenesis include oxidative stress and inflammation in the early stages of AMD. …”
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1871
Melasma management: Unveiling recent breakthroughs through literature analysis
Published 2025-03-01“…Research leveraging histological analyses, genetic profiling, and biochemical assays has elucidated novel therapeutic targets, including oxidative stress pathways and inflammatory mediators. Advances in topical formulations, such as combination therapies containing tyrosinase inhibitors, antioxidants, and anti-inflammatory agents, have shown promising results in improving pigmentation and preventing recurrence. …”
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1872
Antioxidative and Photoprotective Activity of <i>Pinus nigra</i>, <i>Pinus strobus</i> and <i>Pinus mugo</i>
Published 2024-12-01“…Plant-derived antioxidants are a group of compounds that exhibit protective properties against the degenerative effects of oxidative stress on skin aging. Another important factor that protects skin against aging is photoprotective agents. …”
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1873
Emerging trends and new developments in global research on artemisinin and its derivatives
Published 2025-01-01“…Potential areas for future investigations may include ''proliferation,'' ''oxidative stress,'' ''pathways,'' and ''mechanisms.'' Conclusion: This study offers a comprehensive compendium of the developments and trends in the relevant research field over the past fifty years. …”
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1874
Hypertension-Related Gene Polymorphisms of G-Protein-Coupled Receptor Kinase 4 Are Associated with NT-proBNP Concentration in Normotensive Healthy Adults
Published 2012-01-01“…There was no significant association between any of the hypertension-related gene polymorphisms and central systolic blood pressure, cardioankle vascular index, augmentation index, plasma aldosterone concentration, or an oxidative stress marker, urinary 8-OHdG. Normotensive individuals with GRK4 polymorphisms show increased serum NT-proBNP concentration and may be at a greater risk of developing hypertension and cardiovascular disease.…”
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1875
Pengaruh Pemberian Mesenchymal Stem Cells Wharton’s Jelly terhadap Ekspresi Gen PPAR-γ pada Tikus Alzheimer
Published 2023-10-01“…PPAR-γ Gene is suspected to reduce beta-amyloid plaques and reduce inflammation and oxidative stress in Alzheimer's disease. Mesenchymal Stem Cells Wharton's Jelly (MSC-WJ) is expected to increase the PPAR-γ Gene expression. …”
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1876
Glutathione Peroxidase-1 Suppresses the Unfolded Protein Response upon Cigarette Smoke Exposure
Published 2016-01-01“…Oxidative stress provokes endoplasmic reticulum (ER) stress-induced unfolded protein response (UPR) in the lungs of chronic obstructive pulmonary (COPD) subjects. …”
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1877
Potential Health Implications of the Consumption of Thermally-Oxidized Cooking Oils – a Review
Published 2017-06-01“…Furthermore, several in vivo studies had suggested that consumption of thermally-oxidized cooking oils might not be healthy as it might negatively influence the lipid profile (increased low density lipoprotein (LDL), decreased high density lipoprotein (HDL) and elevated cholesterol level), haematological system (alteration in concentration of heamoglobin (Hb), packed cell volume (PCV), white blood cell (WBC) count, neutrophil and lymphocyte counts), kidney function, and induce lipid peroxidation and oxidative stress which have been associated with the pathogenesis of various degenerative diseases. …”
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1878
Pyruvate-Enriched Oral Rehydration Solution Improves Glucometabolic Disorders in the Kidneys of Diabetic db/db Mice
Published 2020-01-01“…Aberrant key enzyme activities in glucometabolic pathways, AR, PK, and PDK/PDH, were also restored; indexes of oxidative stress and inflammation, NAD+/NADH ratio, and AGEs in the kidneys were mostly significantly preserved after pyruvate treatments. …”
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1879
Lactobacillus rhamnosus: An emerging probiotic with therapeutic potential for depression
Published 2025-01-01“…This review preliminarily explores the clinical significance of Lactobacillus rhamnosus in the treatment of depression and summarizes the potential mechanisms by which Lactobacillus rhamnosus treats depression, including its regulation of gut microbiota, alterations in gene expression, improvement of intestinal barrier function, maintenance of neurotransmitter balance, suppression of inflammatory responses, modulation of the immune system, coping with oxidative stress, and optimization of metabolic processes. …”
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1880
Matrine relieved DHAV-1-induced hepatocyte excessive interferon and pyroptosis by activating mitophagy
Published 2025-01-01“…Additionally, by incorporating the autophagy inhibitor chloroquine, we observed that the effects of matrine on the regulation of excessive interferon (IFN) production, pyroptosis, mitochondrial damage, and oxidative stress were reversed. Overall, matrine inhibited excessive IFN production and pyroptosis by promoting mitophagy, suggesting that matrine may act as a possible therapeutic agent for addressing DHAV-1 infection and other viral hepatitis.…”
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