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1821
The injectable hydrogel loading cannabidiol to regulate macrophage polarization in vitro for the treatment of chronic enteritis
Published 2024-10-01“…In addition, GelMA + CBD can also reduce the expression of pro-inflammatory factors (such as iNOS) in macrophages, and increase the expression of anti-inflammatory factors (such as Arg-1), clear intracellular reactive oxygen species (ROS), and relieve oxidative stress. Conclusion: The vitro experiments have confirmed that the CBD-loaded hydrogel system has good biosafety, and can alleviate inflammation by regulating the polarization direction of macrophages, and then inhibiting the secretion of pro-inflammatory factors, laying a strong foundation for the treatment of chronic enteritis.…”
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1822
DPPH Scavenging Activity, Reducing Power, and Metal Chelating Capacity of Compound 1-(2,5-dihydroxyphenyl)-3-pyridine-2-yl-propenone
Published 2023-12-01“…The excessive free radicals in the body could stimulate oxidative stress which has been implicated in several diseases such as cancer, inflammation, aging, and cardiovascular diseases. …”
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1823
Protective effects of Euphorbia heterophylla against testicular degeneration in streptozotocin-induced diabetic rats in relation to phytochemical profile.
Published 2025-01-01“…<h4>Methods and findings</h4>The objective of this study was to profile E. heterophylla ethanol extract (EH-EtOH) and elucidate its protective role in oxidative stress, relieving inflammatory action of hyperglycemia-induced testicular degeneration and restoring the normal histological structure with physiological properties of testicular tissue in streptozotocin (STZ)-induced DM. …”
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1824
Possible Potentiation by Certain Antioxidants of the Anti-Inflammatory Effects of Diclofenac in Rats
Published 2014-01-01“…The results indicated that these combinations did not significantly affect the percentage inhibition of paw edema caused by diclofenac alone; however, some combination treatments ameliorated signs of concomitant oxidative stress (such as alterations in plasma malondialdehyde (MDA) levels, hemolysate reduced glutathione levels, and erythrocytic superoxide dismutase enzyme activities) imparted by diclofenac alone. …”
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1825
Synergistic Effects of Nano-Silicon and IQ Combi on Yield Traits of Wheat under Saline Irrigation
Published 2025-02-01“…Conclusions: The application of nano-fertilizers enhanced yield parameters and increased the antioxidant enzymes as part of the plant's defense mechanism against oxidative stress. Over time, this response to developing salinity-tolerant wheat varieties with strong antioxidant defense systems. …”
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1826
Extender Supplementation with Glutathione (GSH) and Taurine Improves In Vitro Sperm Quality and Antioxidant Status of New Zealand Rabbits during Chilled Storage for up to 72 hours
Published 2023-01-01“…Sperm’s progressive motility, acrosome reaction, and extracellular oxidative stress biomarkers such as MDA contents and GPx, SOD, and CAT concentrations and intracellular transcriptomic levels of SOD and CAT genes were assessed. …”
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1827
Multiple Roles of SIRT2 in Regulating Physiological and Pathological Signal Transduction
Published 2022-01-01“…Therefore, SIRT2 can be involved in metabolic disorder-related inflammation and oxidative stress, thereby triggering the occurrence of metabolic disorder-related diseases, such as neurodegenerative diseases, tumours, diabetes, and cardiovascular diseases. …”
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1828
Effects of dietary addition of mulberry leaf powder on blood metabolites and fecal microbiota composition in Hu sheep
Published 2025-01-01“…In livestock production, ruminant feed resources are often scarce, and numerous challenges arise during production, such as immune disorders and oxidative stress. Mulberry leaves are rich in various nutrients and exhibit significant antioxidant and immune-regulating properties. …”
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1829
Antioxidants from microalgae and their potential impact on human well-being
Published 2024-05-01“…These antioxidants play a pivotal role in scavenging free radicals and reducing oxidative stress, known contributors to aging and chronic diseases. …”
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1830
In Vitro Studies of Anti-Hemolytic and Cytotoxic Activity of Procyanidin-Rich Extract from the Leaves of Actinidia arguta
Published 2018-06-01“…Therefore, it can be used in the prevention of diseases, especially those related to oxidative stress.…”
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1831
Comparative Study of Antioxidant Status in Androgenic Embryos of Aesculus hippocastanum and Aesculus flava
Published 2014-01-01“…However, the leaves of A. flava showed higher antioxidant activity than the leaves of A. hippocastanum, and therefore they have a stronger tolerance of oxidative stress. Androgenic embryos of both species had low amount of antioxidants due to controlled in vitro environmental conditions (T, photoperiod, humidity, nutritive factors, and pathogen-free). …”
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1832
Sulfoxidation of pyrimidine thioate derivatives and study their biological activities
Published 2025-01-01“…Excitingly, compounds 12 and 6 showcased robust antioxidant activity by efficiently scavenging DPPH• radical, underscoring their potential in oxidative stress mitigation. Notably, compounds 10 and 12 displayed promising anti-tumor effects, with compound 12 demonstrating superior efficacy against the MCF-7 breast cancer cell line compared to compound 10. …”
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1833
Plasma concentration of MMP-17 is elevated in boys with cryptorchidism and correlates with HSP-70
Published 2025-01-01“…The pathogenesis of undescended testes is unknown however the role of inflammation, tissue remodeling and oxidative stress is postulated. The aim of this study was to explore the role of HSP-70, MMP-3, MMP-17 and IL-8 in possible pathogenic pathways connected with cryptorchidism. …”
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1834
Optimizing conditions to improve polyphenol content and screening antioxidant capacity with DNA protection activity of Perilla frutescens
Published 2024-06-01“… Polyphenols are among the natural antioxidants that have been exploited in recent years for their safe and effective ability against oxidative stress. This project aimed to optimize 3 factor-conditions affecting total polyphenols extracted from Perilla frutescens (L.) …”
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1835
Movement in the Shadow of Sadness: How Physical Activity Supports the Fight Against Depression
Published 2025-02-01“…Additionally, physical effort reduces inflammation and oxidative stress, supporting brain health and countering neurodegenerative processes. …”
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1836
A Review on The Impact of Thermal Stress on Fish Biochemistry
Published 2024-03-01“…Cumulative effects of thermal stress induce oxidative stress, causing cell death, organ failure, and mortality. …”
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1837
Association between oxidative balance score and gallstone disease: a population-based study from NHANES
Published 2025-01-01“…BackgroundOxidative stress has been reported to participant in the pathogenesis of gallstones. …”
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1838
Reactive Oxygen Species, SUMOylation, and Endothelial Inflammation
Published 2012-01-01“…Although the exact mechanism through which NADPH oxidases (Nox’s) generate reactive oxygen species (ROS) is still not completely understood, it is widely considered that ROS accumulation is the cause of oxidative stress in endothelial cells. Increasing pieces of evidence strongly indicate the role for ROS in endothelial inflammation and dysfunction and subsequent development of atherosclerotic plaques, which are causes of various pathological cardiac events. …”
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1839
Hmox1 Deficiency Sensitizes Mice to Peroxynitrite Formation and Diabetic Glomerular Microvascular Injuries
Published 2017-01-01“…This was associated with a renal increase in the expression of the oxidative stress marker, nitrotyrosine. Conclusions. Genetic Hmox1 partial deficiency is sufficient to sensitize mice to the development of diabetic glomerular microvascular lesions. …”
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1840
The Efficacy and Mechanism of Chinese Herbal Medicine on Diabetic Kidney Disease
Published 2019-01-01“…In terms of experimental research, studies provided evidence for the efficacy of CHM from the perspectives of balancing metabolic disorders, reducing inflammatory response and oxidative stress, antifibrosis, protecting renal innate cells, and regulating microRNA and metabolism. …”
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