Metabolomic Signatures Influenced by Different Cardioplegic Solutions in Cardiac Surgery by Chananya Karunasumetta, Chotika Chatgasem, Suriya Punchai, Kittisak Sawanyawisuth

“…These DEMs were associated with protein and energy production, oxidative stress, and inflammatory responses. Key differential metabolites between the groups included histidine and alanine, which notably impacted the histidine metabolism pathway. …”
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Mitochondrial transplantation: a promising strategy for the treatment of retinal degenerative diseases by Jing Chi, Bin Fan, Yulin Li, Qing Jiao, Guang-Yu Li

“…However, in retinal degenerative diseases, mitochondrial dysfunction significantly contributes to disease progression, involving a decline in membrane potential, the occurrence of DNA mutations, increased oxidative stress, and imbalances in quality-control mechanisms. …”
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Hepatic transcript profiling in beef cattle: Effects of rumen-protected niacin supplementation. by Gastón F Alfaro, Valentino Palombo, Mariasilvia D'Andrea, Wenqi Cao, Yue Zhang, Jonathan Beever, Russell B Muntifering, Wilmer J Pacheco, Soren P Rodning, Xu Wang, Sonia J Moisá

“…Several metabolic pathways revealed potential positive effects to the animal's liver metabolism due to administration of rumen-protected niacin; for example, a decrease in lipolysis, apoptosis, inflammatory responses, atherosclerosis, oxidative stress, fibrosis, and vasodilation-related pathways. …”
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Matched serum- and urine-derived biomarkers of interstitial cystitis/bladder pain syndrome. by Tadeja Kuret, Igor Sterle, Rok Romih, Peter Veranič

“…A total of 33 different biomarkers were measured, including cytokines and chemokines, proteins involved in extracellular matrix remodeling, adhesion molecules, growth factors, and markers of oxidative stress using enzyme linked immunoassays and multiplex technology. …”
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The Role of Inflammation in the Pathogenesis of Preeclampsia by Michał Michalczyk, Aleksander Celewicz, Marta Celewicz, Paula Woźniakowska-Gondek, Rafał Rzepka

“…Some significant factors responsible for PE development include oxidative stress, abnormal concentration and activity in mononuclear phagocytic system, altered levels of angiogenic and antiangiogenic factors, and impaired inflammatory response triggered by inflammasomes. …”
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Climate change, air pollution and chronic respiratory diseases: understanding risk factors and the need for adaptive strategies by Jiayu Xu, Zekang Su, Chenchen Liu, Yuxuan Nie, Liangliang Cui

“…Potential pathophysiological mechanisms linking climate change and increased risk of CRD involved pulmonary inflammation, immune disorders, oxidative stress. Notably, the elderly, children, impoverished groups and people in regions with limited adaptability are more sensitive to respiratory health risks caused by climate change. …”
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Serum Uric Acid, Alanine Aminotransferase, Hemoglobin and Red Blood Cell Count Levels in Pseudoexfoliation Syndrome by Hüseyin Simavlı, Yasin Yücel Bucak, Mehmet Tosun, Mesut Erdurmuş

“…The pathogenesis of pseudoexfoliation (PEX), the most common cause of secondary glaucoma, has not been clearly identified, but there is increasing evidence that points out the role of oxidative stress. The aim of this study is to evaluate some of the most commonly used blood parameters, hemoglobin (Hb), red blood cell count (RBC), alanine aminotransferase (ALT), and uric acid (UA) levels, in subjects with PEX. …”
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Therapeutic Effects of Milk Thistle (Silybum marianum L.) and Artichoke (Cynara scolymus L.) on Nonalcoholic Fatty Liver Disease in Type 2 Diabetic Rats by Aida Doostkam, Mohammad Fathalipour, Mohammad Hossein Anbardar, Azar Purkhosrow, Hossein Mirkhani

“…After the end of the intervention, oral glucose tolerance, the serum parameters of oxidative stress, liver functional tests, and lipid profiles were evaluated. …”
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INTENSITY OF NITRIC OXIDE SYNTHESIS IN THE BLOOD OF RATS UNDER THE INFLUENCE OF SODIUM FLUORIDE by I.L. Kolisnyk

“…Oral administration of FN to rats in doses of 1/10 and 1/100 DL50 leads to an increase in the content of nitrite and nitrate anions in the blood plasma during the first 30 days, which indirectly indicates excess production of nitric oxide, which in the initial stages of intoxication may play a compensatory role, but subsequently cause pathological reactions associated with the activation of oxidative stress. The decrease in nitrite and nitrate anions at the end of long-term action of FN indirectly indicates a decrease in nitric oxide generation, which may be associated, in particular, with an increase in peroxynitrite concentration due to the use of nitric oxide in reaction with superoxide anion radical and antioxidant deficiency.…”
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Polysaccharides of St. John’s Wort Herb Stimulate NHDF Proliferation and NEHK Differentiation via Influence on Extracellular Structures and Signal Pathways by S. Abakuks, A. M. Deters

“…This effect was related to the influence on genes that referred to oxidative stress, metabolism, transcription processes and extracellular proteins. …”
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Targeting Inflammation in Emerging Therapies for Genetic Retinal Disease by Ishaq A. Viringipurampeer, Abu E. Bashar, Cheryl Y. Gregory-Evans, Orson L. Moritz, Kevin Gregory-Evans

“…Diverse genetic abnormalities and environmental causes have been implicated in triggering multiple pathological mechanisms such as oxidative stress, lipofuscin deposits, neovascularisation, and programmed cell death. …”
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Biochemical Factors Modulating Cellular Neurotoxicity of Methylmercury by Parvinder Kaur, Michael Aschner, Tore Syversen

“…This paper emphasizes that the protection against oxidative stress offered by these biochemical factors is among one of the major mechanisms responsible for conferring neuroprotection. …”
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Dysregulated Functions of Lung Macrophage Populations in COPD by Theodore S. Kapellos, Kevin Bassler, Anna C. Aschenbrenner, Wataru Fujii, Joachim L. Schultze

“…We primarily focus on the dysregulated capacity of alveolar macrophages to secrete proinflammatory mediators and proteases, induce oxidative stress, engulf microbes and apoptotic cells, and express surface and intracellular markers in patients with COPD. …”
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Gamisoyo-San Ameliorates Neuroinflammation in the Spinal Cord of hSOD1G93A Transgenic Mice by MuDan Cai, Eun Jin Yang

“…Moreover, we found that GSS inhibits the expression of proteins related to Toll-like receptor 4 signaling and oxidative stress, known to cause neuroinflammation. Notably, GSS also regulates metabolism in the spinal cord of transgenic mice. …”
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Helicobacter pylori and gastric cancer: mechanisms and new perspectives by Yantao Duan, Yonghu Xu, Yi Dou, Dazhi Xu

“…Furthermore, we highlight the role of H. pylori in inducing oxidative stress, DNA damage, chronic inflammation, and cell apoptosis—key cellular events that pave the way for carcinogenesis. …”
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New Insights into Chemical Profiles and Health-Promoting Effects of Edible Mushroom <i>Dictyophora indusiate</i> (Vent ex. Pers.) Fischer: A Review by Yogesh Kumar, Baojun Xu

“…In particular, polysaccharides from <i>Dictyophora indusiata</i> (DIP) enhance immune function, reduce oxidative stress, and promote gut health as prebiotics. …”
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Roles of Brain Angiotensin II in Cognitive Function and Dementia by Masaki Mogi, Jun Iwanami, Masatsugu Horiuchi

“…A direct AT2 receptor agonist is now available and is expected to reduce inflammation and oxidative stress and enhance cell differentiation. We and other groups reported that AT2 receptor activation enhances neuronal differentiation and neurite outgrowth in the brain. …”
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Impact of the Ketogenic Diet on Neurological Diseases: A Review by Carmen Rubio, Alejandro López-Landa, Hector Romo-Parra, Moisés Rubio-Osornio

“…Discussion: KD is associated with neuroprotective and antioxidant effects that improve mitochondrial function, regulate neurotransmitter flow, and reduce neuroinflammation and oxidative stress. Glial cells play an essential role in the utilization of ketone bodies (KBs) within the central nervous system’s metabolism, particularly during ketosis induced by the KD. …”
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Phosphorylation of a nuclear condensate regulates cohesion and mRNA retention by Alexa B. R. McIntyre, Adrian Beat Tschan, Katrina Meyer, Severin Walser, Arpan Kumar Rai, Keisuke Fujita, Lucas Pelkmans

“…We further find that cellular responses to heat shock, oxidative stress, and hypoxia include changes to the phosphorylation and cohesion of nuclear speckles and to mRNA retention. …”
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Vitamin D on the susceptibility of gestational diabetes mellitus: a mini-review by Ting Zhang, Ting Zhang, Lan Yang, Shuman Yang, Song Gao

“…Vitamin D can regulate the course of gestational diabetes, which may be related to regulation of insulin gene transcription, insulin secretion, intracellular and cytosolic calcium balance, inhibition of oxidative stress and inflammatory responses and alteration of glucose metabolism. …”
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