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1501
Hypothesis: glyphosate-based herbicides can increase risk of hematopoietic malignancies through extended persistence in bone
Published 2025-01-01“…Studies confirm that GLY and glyphosate-based herbicides (GBHs) can trigger oxidative stress and impair DNA-repair mechanisms. Animal bioassays and epidemiology studies link GLY/GBH exposures to heightened risk of blood cancers, and possibly other pathologies. …”
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1502
Effect of Supplementation with Antioxidants on the Quality of Bovine Milk and Meat Production
Published 2013-01-01“…From a clinical point of view, oxidative stress (OS) is considered the primary cause of numerous metabolic processes in transition cow. …”
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1503
Advances in Knowledge Regarding Arterial Curvature and its Relationship to Ischemic Stroke: A Narrative Review
Published 2025-01-01“…Furthermore, the haemodynamic changes associated with arterial curvature can result in reduced cerebral perfusion pressure, endothelial dysfunction, oxidative stress, and inflammatory responses. These factors contribute to the development of atherosclerosis and the formation of arterial dissections. …”
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1504
Mitochondrial Dysfunction as a Therapeutic Target in Diabetic Cardiomyopathy: Progress and Prospects
Published 2025-01-01“…Recent studies have highlighted the crucial roles of mitochondrial dysfunction in the pathogenesis of DCM, including aspects such as glucose-lipid metabolic disorder, oxidative stress damage, calcium regulation disorder, respiratory chain uncoupling, kinetic imbalance, and mitochondrial DNA damage. …”
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1505
The role of glial cells in neuralgia: a bibliometric exploration
Published 2025-02-01“…Keyword analysis highlights research hotspots focusing on glial cell activation, spinal cord injury, satellite glial cells, oxidative stress, and neuroinflammation. The findings suggest that these themes may shape future directions in the field. …”
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1506
Progress on long non-coding RNAs in calcific aortic valve disease
Published 2025-01-01“…The aortic valve, influenced by factors such as endothelial dysfunction, inflammation, oxidative stress, lipid metabolism disorders, calcium deposition, and extracellular matrix remodeling, undergoes fibrosis and calcification, ultimately leading to stenosis. …”
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1507
Species-Related Differences in the Proteome of Rat and Human Pancreatic Beta Cells
Published 2015-01-01“…Besides conferring lower susceptibility to oxidative stress to human cells PRDX3 might also play a role in physiological redox regulation as, in rat, its expression was restricted to a beta cell subset with higher metabolic glucose responsiveness. …”
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1508
The effect of caloric restriction on genetical pathways
Published 2023-09-01“…By Forkhead box O (FoxO) transcription factors, the ability of resistance to oxidative stress increases, and antioxidant genes, DNA repair, and autophagy genes are stimulated. …”
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1509
Ferroptosis: mechanism and role in diabetes-related cardiovascular diseases
Published 2025-02-01“…The susceptibility to ferroptosis in diabetic hearts is possibly related to myocardial iron accumulation, abnormal lipid metabolism and excess oxidative stress under hyperglycemia conditions. Accumulating evidence suggests ferroptosis can be the therapeutic target for diabetic cardiovascular diseases. …”
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1510
Insulin/IGF-I and Related Signaling Pathways Regulate Aging in Nondividing Cells: from Yeast to the Mammalian Brain
Published 2010-01-01“…We will focus on the role of yeast signal transduction proteins Ras, Tor, Sch9, Sir2, their homologs in higher organisms, and their association to oxidative stress and protective systems. We will discuss how the “molecular strategy” responsible for life span extension in response to dietary and genetic manipulations appears to be remarkably conserved in various organisms and cells, including neuronal cells in different organisms. …”
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1511
Phytochemicals, Nutritional and Elemental Composition of different plant parts of Rinorea oblongifolia (C.H Wright) C. Marquand ex Chipp
Published 2024-12-01“… Antioxidants are essential in managing chronic diseases by neutralizing free radicals and reducing oxidative stress. Rinorea oblongifolia, a medicinal plant, contains a rich profile of phytochemicals and minerals, adding to its therapeutic potential. …”
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1512
Anti-Inflammatory Activity and Free Radical Scavenging Activity of Tridax Procumbens Leaves-Based Chitosan Gel
Published 2024-12-01“…Conclusion: The anti-inflammatory and antioxidant assay results demonstrate that the investigated compounds, notably TP leaves extract-based chitosan gel, have the potential to be effective agents in moderating oxidative stress and lowering inflammation.…”
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1513
Impact of Exposure to Fenitrothion on Vital Organs in Rats
Published 2016-01-01“…Fenitrothion also caused a decrease in cholinesterase activity in serum, lung, and brain activity associated with a state of oxidative stress in all tested organs and hyperammonemia. …”
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1514
Phosphate, Calcification in Blood, and Mineral Stress: The Physiologic Blood Mineral Buffering System and Its Association with Cardiovascular Risk
Published 2018-01-01“…The relative abundance and biological activity of these particles are a matter of intense research, because they can cause oxidative stress, inflammation, and calcification in cellular assay. …”
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1515
Metabolic Analysis of the Mode of Action and Mode of Resistance for Novobiocin in Staphylococcus aureus
Published 2025-01-01“…The gyrB mutation was the primary driver of resistance, and was associated with changes in growth, survival under surface and oxidative stress, cell wall permeability, and coagulation functions. …”
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1516
Mechanisms of liver disease in patients infected with HIV
Published 2017-10-01“…A thorough understanding of the mechanisms driving the development of liver disease in these patients is essential when evaluating and caring for these patients.Methods The literature regarding mechanisms of liver disease by which different disease entities may cause hepatic injury and fibrosis was reviewed and synthesised.Results A number of discrete mechanisms of injury were identified, to include: oxidative stress, mitochondrial injury, lipotoxicity, immune-mediated injury, cytotoxicity, toxic metabolite accumulation, gut microbial translocation, systemic inflammation, senescence and nodular regenerative hyperplasia. …”
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1517
The application of procyanidins in diabetes and its complications: a review of preclinical studies
Published 2025-02-01“…PCs, recognized for their strong antioxidant, anti-inflammatory, and anti-hyperglycemic properties, play a crucial role in reducing oxidative stress and enhancing endothelial function, which are essential for managing diabetic complications. …”
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1518
Age-Dependent Paraoxonase 1 (PON1) Activity and LDL Oxidation in Wistar Rats during Their Entire Lifespan
Published 2014-01-01“…Paraoxonase 1 (PON1) is an HDL bound enzyme which plays a key role in the protection of LDL and HDL from oxidation by hydrolyzing activated phospholipids and lipid peroxide products. Oxidative stress plays a crucial role in the development of atherosclerosis by oxidation of LDL. …”
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1519
Preparation and Synergistic Anti-Tumor Effect of Iridium Oxide Nanocomposites under Microscope
Published 2022-01-01“…At the same time, IrOx, as a sound-sensitive agent, can produce ROS under US irradiation, amplify intracellular oxidative stress, accelerate tumor cell death, and finally achieve the effect of SDT chemotherapy synergistic therapy. …”
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1520
Protective Effect of Baccharis trimera Extract on Acute Hepatic Injury in a Model of Inflammation Induced by Acetaminophen
Published 2014-01-01“…The liver-function markers ALT and AST, biomarkers of oxidative stress, antioxidant parameters, and histopathological changes were examined. …”
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