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1481
Effect of DiD Carbocyanine Dye Labeling on Immunoregulatory Function and Differentiation of Mice Mesenchymal Stem Cells
Published 2014-01-01“…Therefore, in the present study the consequences of DiD labeling on induction of oxidative stress and apoptosis as well as inhibition of biological functions of mesenchymal stem cells (MSCs) were investigated. …”
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1482
Cardiovascular Effects Mediated by HMMR and CD44
Published 2021-01-01“…One of the factors involved in CVD development among vascular damage and oxidative stress is chronic inflammation. It is known that hyaluronic acid plays an important role in inflammation and is regulated by numerous stimuli, including proinflammatory cytokines. …”
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1483
Serotonin and Its Receptor as a New Antioxidant Therapeutic Target for Diabetic Kidney Disease
Published 2017-01-01“…The 5-HT receptor (5-HTR) antagonists exert renoprotective effects by suppressing oxidative stress, suggesting that 5-HTR can be used as a potential target for treating DKD. …”
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1484
Ferroptosis: A New Pathway in the Interaction between Gut Microbiota and Multiple Sclerosis
Published 2025-01-01“…Ferroptosis, driven by lipid peroxidation and tightly linked to iron metabolism, is a pivotal contributor to the oxidative stress observed in MS. Concurrently, the gut microbiota, known to affect systemic immunity and neurological health, emerges as an important regulator of iron homeostasis and inflammatory responses, thereby influencing ferroptotic pathways. …”
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1485
Effect of Antioxidants in the Treatment of COPD Patients: Scoping Review
Published 2021-01-01“…The beneficial effect of antioxidants in stable or exacerbated patients is not clear, but theoretical and biological arguments of benefit justify lines of research that specify the impact on reducing oxidative stress and negative effects in COPD.…”
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1486
The Mammary Gland Carcinogens: The Role of Metal Compounds and Organic Solvents
Published 2013-01-01“…The four most predominant mechanisms for metal carcinogenicity include (1) interference with cellular redox regulation and induction of oxidative stress, (2) inhibition of major DNA repair, (3) deregulation of cell proliferation, and (4) epigenetic inactivation of genes by DNA hypermethylation. …”
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1487
A Systems Biology Overview on Human Diabetic Nephropathy: From Genetic Susceptibility to Post-Transcriptional and Post-Translational Modifications
Published 2016-01-01“…The picture that emerges is complex and fascinating as it includes the regulation/dysregulation of numerous biological processes, converging toward the activation of inflammatory processes, oxidative stress, remodeling of cellular function and morphology, and disturbance of metabolic pathways. …”
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1488
Nonalcoholic Fatty Liver Disease and Sarcopenia: Where Do We Stand?
Published 2020-01-01“…Crucial mechanisms involved in sarcopenia-nonalcoholic fatty liver disease (NAFLD) interplay are based on effects of insulin resistance, chronic inflammation, oxidative stress, and crosstalk between organs by secretion of cytokines (hepatokines, adipokines, and myokines). …”
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1489
Exertion in Kangoo Jumps Aerobic: Evaluation and Interpretation Using Spectroscopic Technique Determinations
Published 2013-01-01“…The ongoing paper is aiming to investigate the evaluation of oxidative stress in womens practicing Kangoo Jumps (KJ) aerobics. …”
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1490
Nutritional and Therapeutic Potential of Soursop
Published 2022-01-01“…Since soursop contains various phytochemicals, it can be used medicinally to treat a wide range of conditions, including diabetes (by inhibiting the enzymes α-glucosidase and α-amylase), tumor, cancer, oxidative stress, blood pressure, the induction of apoptosis in tumor cells as well as hemorrhagic disease and cholesterol lowering. …”
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1491
Nanocurcumin in myocardial infarction therapy: emerging trends and future directions
Published 2025-01-01“…Preclinical studies revealed that nanocurcumin drastically lower oxidative stress indicators, inflammatory cytokines, and cardiac damage. …”
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1492
Advances in Selenium and Related Compounds Inhibiting Multi-Organ Fibrosis
Published 2025-01-01“…Xixi Xiao,1 Guoquan Huang,2,3 Xinqiao Yu,2 Yong Tan2,3 1The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture, Hubei Minzu University, Enshi, 445000, People’s Republic of China; 2Hubei Selenium and Human Health Institute, The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture, Enshi, 445000, People’s Republic of China; 3Hubei Provincial Key Laboratory of Selenium Resources and Bioapplications, Enshi, 445000, People’s Republic of ChinaCorrespondence: Xinqiao Yu; Yong Tan, Email 1361095717@qq.com; tanyong951018@163.comAbstract: Selenium (Se), a critically essential trace element, plays a crucial role in diverse physiological processes within the human body, such as oxidative stress response, inflammation regulation, apoptosis, and lipid metabolism. …”
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1493
Rebamipide during chronic gastritis: <i>H. pylori</i> eradication therapy and restoration of gastric mucosa barrier function
Published 2024-01-01“…Experimental and clinical studies have demonstrated that rebamipide increases concentration of prostaglandins (prostaglandin E2 and prostacyclin) and production of mucin, manages inflammation and oxidative stress, controls apoptosis and autophagy. Pleiotropic effects of rebamipide are aimed at restoration of epithelium barrier function and can be implemented during chronic gastritis for various indications. …”
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1494
Estrogens as Antioxidant Modulators in Human Fertility
Published 2013-01-01“…On the other hand, oxidative stress is a mechanism well recognized for deleterious effects on spermatozoa function. …”
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1495
αSynuclein and Mitochondrial Dysfunction: A Pathogenic Partnership in Parkinson’s Disease?
Published 2012-01-01“…Candidates discussed within this review include autophagy, mitophagy, mitochondrial dynamics/fusion/fission, oxidative stress and reactive oxygen species, endoplasmic reticulum stress, calcium, nitrosative stress and αSynuclein Oligomerization.…”
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1496
Suppression of the Oncogenic Transcription Factor FOXM1 by Proteasome Inhibitors
Published 2014-01-01“…Using RNA-interference or proteasome inhibitors to inhibit FOXM1 we found that suppression of FOXM1 sensitized human cancer cells to apoptosis induced by DNA-damaging agents or oxidative stress. We encapsulated thiostrepton into micelle-nanoparticles and after injection we detected accumulation of nanoparticles in tumors and in the livers of treated mice. …”
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1497
Anti-Parkinson Activity of Petroleum Ether Extract of Ficus religiosa (L.) Leaves
Published 2016-01-01“…Thus, the study proved that Ficus religiosa treatment significantly attenuated the motor defects and also protected the brain from oxidative stress.…”
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1498
Mitochondrial dysfunction in Alzheimer’s disease: a key frontier for future targeted therapies
Published 2025-01-01“…Mitochondrial dysfunction primarily leads to increased oxidative stress, imbalances in mitochondrial dynamics, impaired mitophagy, and mitochondrial genome abnormalities. …”
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1499
The Loss of HIF1α Leads to Increased Susceptibility to Cadmium-Chloride-Induced Toxicity in Mouse Embryonic Fibroblasts
Published 2011-01-01“…The total and oxidized glutathione levels, and, correspondingly, lipid peroxidation levels were elevated in the null cells compared to wild-type cells, indicating increased antioxidant demand and greater oxidative stress. Overall, the results suggest that basal levels of HIF1α play a protective role against cadmium-induced cytotoxicity in mouse embryonic fibroblasts by maintaining metallothionein and antioxidant activity levels.…”
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1500
Microcystins Induces Vascular Inflammation in Human Umbilical Vein Endothelial Cells via Activation of NF-κB
Published 2015-01-01“…Taken together, the present data suggested that MC-LR induced vascular inflammatory process, which may be closely related to the oxidative stress, NF-κB activation, and cell adhesion molecules expression in HUVECs. …”
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