Melatonin and Ischemic Stroke: Mechanistic Roles and Action by Syed Suhail Andrabi, Suhel Parvez, Heena Tabassum

“…The various cascades of events that have been associated with stroke involve oxidative stress, excitotoxicity, mitochondrial dysfunction, upregulation of Ca2+ level, and so forth. …”
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Research Progress on Alleviatory Effects of 6-Gingerol and 6-Shogaol on Intestine Tight Junction Damage by LI Yu, OUYANG Fangxin, ZHANG He, WANG Wenyu, DONG Jingxiao, LI Dapeng, LI Feng

“…Through comprehensive analysis of clinical research and experimental results in recent years, it is found that 6-gingerol and 6-shogaol can improve the expression levels of tight junction-related proteins and maintain the integrity and biofunction of the intestinal barrier by inhibiting inflammation, oxidative stress and apoptosis as well as regulating the composition of intestinal microbiota. …”
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SIRT1 Regulates Cognitive Performance and Ability of Learning and Memory in Diabetic and Nondiabetic Models by Yue Cao, Zi Yan, Tong Zhou, Guixia Wang

“…In the present study, deacetylation, oxidative stress, mitochondrial dysfunction, inflammation, microRNA, and tau phosphorylation are considered in the context of mechanism and significance of SIRT1 in learning and memory in diabetic and nondiabetic murine models. …”
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Sirtuins and Their Implications in the Physiopathology of Gestational Diabetes Mellitus by Katarzyna Zgutka, Marta Tkacz, Marta Grabowska, Wioletta Mikołajek-Bedner, Maciej Tarnowski

“…Chronic low-grade inflammation, oxidative stress, and insulin resistance are central features of pregnancies complicated by GDM. …”
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The hypoglycemic potential of phenolics from functional foods and their mechanisms by Oksana Golovinskaia, Chin-Kun Wang

“…Chronic hyperglycemia induces the glycation of proteins, oxidative stress, inflammation and increases plasma insulin and lipid concentrations. …”
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Metallothionein-3-mediated intracellular zinc mediates antioxidant and anti-inflammatory responses in the complete Freund’s adjuvant-induced inflammatory pain mouse model by Ngoc Buu Tran, Sook-Jeong Lee

“…Furthermore, intracellular Zn2+ was crucial in regulating oxidative stress markers (glutathione, superoxide dismutase, catalase, and malondialdehyde) and inflammatory cytokines, such as tumor necrosis factor-α and interleukin-6, in MT3 knockout mice induced with CFA. …”
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Sirtuin activators as an anti-aging intervention for longevity by Puja Sah, Anita K. Rai, Donkupar Syiem

“…The mammalian sirtuins comprise seven members that have a role in energy metabolism, DNA repair, inflammation, cell survival, apoptosis, cellular senescence, oxidative stress, and mitochondrial production. Sirtuin modulation may have beneficial effects on aging and age-related diseases; thus, attracting a growing interest in discovering small molecules modifying their activity. …”
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When HSFs bring the heat—mapping the transcriptional circuitries of HSF-type regulators in Candida albicans by Sadri Znaidi

“…C. albicans HSFs do not only respond to heat shock and/or temperature variation but also to CO2 levels, oxidative stress, and quorum sensing, acting this way as central decision makers. …”
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Hallmarks of aging: middle-aging hypovascularity, tissue perfusion and nitric oxide perspective on healthspan by Teow J. Phua

“…These processes also involve oxidative stress and inflammation triggered by hypoxia.…”
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Evaluation of Selenoprotein Supplementation on Digestibility, Growth, and Health Performance of Pacific White Shrimp Litopenaeus vannamei by Rafi Kemal, Ichsan Achmad Fauzi, Sri Nuryati, Wira Wisnu Wardani, Muhammad Agus Suprayudi

“…Selenoprotein is a feed additive that can overcome oxidative stress in intensive Pacific white shrimp (Litopenaeus vannamei) culture. …”
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In silico approach in the development of structural analogues of resveratrol with improved distribution in the central nervous system by Mitrović Darko, Pavlović Nebojša

“…Resveratrol exerts neuroprotective effects that are not only due to anti inflammatory and antioxidant activity but also by launched biogenesis via sirtuin-1 (SIRT1) protein that protects cells from oxidative stress. Resveratrol has low bioavailability due to low aqueous solubility and rapid metabolism. …”
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Key Signaling Pathways Regulate the Development and Survival of Auditory Hair Cells by Yao Liu, Mei Wei, Xiang Mao, Taisheng Chen, Peng Lin, Wei Wang

“…The role of the mitogen-activated protein kinase (MAPK), phosphoinositide-3 kinase/protein kinase B (PI3K/Akt), Notch/Wnt/Atoh1, calcium channels, and oxidative stress/reactive oxygen species (ROS) signaling pathways are the most relevant. …”
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The micro(nano)plastics perspective: exploring cancer development and therapy by Xiangying Deng, Yajun Gui, Lin Zhao

“…Microplastics are capable of triggering cytotoxicity and chronic inflammation, and may promote cancer through mechanisms such as pro-inflammatory responses, oxidative stress and endocrine disruption. In addition, improved microplastics bring new perspectives to cancer therapy, and studies of microplastics as drug carriers are underway, showing potential for high targeting and bioavailability. …”
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Consequences of Hyperoxia and the Toxicity of Oxygen in the Lung by William J. Mach, Amanda R. Thimmesch, J. Thomas Pierce, Janet D. Pierce

“…Protective antioxidant defenses can become overwhelmed with ROS leading to oxidative stress. Activated alveolar capillary endothelium is characterized by increased adhesiveness causing accumulation of cell populations such as neutrophils, which are a source of ROS. …”
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EVALUATION OF THE THERAPEUTIC EFFECTS OF SALVIA ROSMARINUS ESSENTIAL OIL ON NERVOUS SYSTEM DISORDERS by Malina Mihaela Visternicu, Viorica Rarinca, Vasile Burlui, Alin Ciobica

“…Preclinical and clinical research suggests that rosemary extracts, through their active compounds, may enhance cognitive function, protect neurons from oxidative stress, and modulate neurotransmitters involved in cognitive and emotional processes. …”
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Inhibition of miMOMP-induced SASP to combat age-related disease by Xiaoli Liao, Zhennan Guo, Zhennan Guo, Mouhai He, Yichun Zhang

“…This process is triggered by various stimuli, including oxidative stress, chromatin modifications and oncogene activation, characterized by irreversible cell-cycle arrest, resistance to apoptosis and the induction of a complex senescent associated secretory phenotype (SASP). …”
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Mitochondrial Dysfunction in Parkinson's Disease by P. C. Keane, M. Kurzawa, P. G. Blain, C. M. Morris

“…This inhibition leads to the generation of reactive oxygen species and depletion of cellular energy levels, which can consequently cause cellular damage and death mediated by oxidative stress and excitotoxicity. A number of genes that have been shown to have links with inherited forms of PD encode mitochondrial proteins or proteins implicated in mitochondrial dysfunction, supporting the central involvement of mitochondria in PD. …”
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Iron depletion in “metabolic fatty liver syndromes”: a strong biological rationale with disappointing liver outcomes by Amedeo Lonardo

“…Iron plays a key role in many of the key pathogenic steps concurring in the development and progression of MFLS, notably including genetics, intestinal dysbiosis, adipositis, insulin resistance, metaflammation, oxidative stress and ferroptosis, endoplasmic reticulum stress, and hepatic fibrosis. …”
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Evaluation of renoprotective effect of Chinese chive extracts on adenine-induced chronic renal failure by Qiang-Ming Li, Jian-Ping Luo, Li-Hua Pan, Xue-Qiang Zha

“…Meanwhile, it could be found that renal oxidative stress and inflammation of CRF mice were remarkably inhibited by CCWE. …”
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Polydatin Protects Bone Marrow Stem Cells against Oxidative Injury: Involvement of Nrf 2/ARE Pathways by Meihui Chen, Yu Hou, Dingkun Lin

“…Taken together, our results indicate that polydatin could be used in combination with BMSCs for the treatment of spinal cord injury by improving the cell survival and oxidative stress microenvironments.…”
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