-
1141
S100A8-CAMKK2-AMPK axis confers the protective effects of mild hypothermia against cerebral ischemia-reperfusion injury in rats
Published 2025-01-01“…Similarly to MH, knock-down of S100A8 significantly reduced neuronal oxidative stress, attenuated mitochondrial damage, inhibited apoptosis, and improved cognitive function in IR rats. …”
Get full text
Article -
1142
Protective Effect of Acacia nilotica (L.) against Acetaminophen-Induced Hepatocellular Damage in Wistar Rats
Published 2013-01-01“…The present study undoubtedly provides a proof that hepatoprotective action of A. nilotica extract may rely on its effect on reducing the oxidative stress in acetaminophen-induced hepatic damage in rat model.…”
Get full text
Article -
1143
Glia and TRPM2 Channels in Plasticity of Central Nervous System and Alzheimer’s Diseases
Published 2016-01-01“…TRPM2 also modulates oxidative stress and inflammation through interaction with glial cells. …”
Get full text
Article -
1144
Hepatoprotector in cases of dengue hemorrhagic fever as a prevention of hepatic damage: a case report
Published 2023-07-01“…The use of curcumin can reduce serum levels of transaminase, Malondialdehyde (MDA) or markers of oxidative stress and increase hepatic glutathione concentrations which work in free radical detoxication, while the role of UDCA is as a hepatoprotector by reducing the level of oxidative stress in liver cells.…”
Get full text
Article -
1145
Redox Signaling in Diabetic Nephropathy: Hypertrophy versus Death Choices in Mesangial Cells and Podocytes
Published 2015-01-01“…This review emphasizes the role of oxidative stress in diabetic nephropathy, acting as trigger, modulator, and linker within the complex network of pathologic events. …”
Get full text
Article -
1146
RNA Viruses: ROS-Mediated Cell Death
Published 2014-01-01“…Much evidences has accumulated over the past decade, suggesting that patients infected with RNA viruses are under chronic oxidative stress. Changes to the body’s antioxidant defense system, in relation to SOD, ascorbic acid, selenium, carotenoids, and glutathione, have been reported in various tissues of RNA-virus infected patients. …”
Get full text
Article -
1147
Impacts of micro- and nanoplastic exposure on the cardiovascular system: a systematic review focused on in vivo studies
Published 2024-12-01“…Studies reveal that MPs and NPs cause cardiovascular toxicity through deposition, morphological changes, biomarker alterations, metabolism changes, and genetic regulation related to injury, inflammation, and oxidative stress. This study is limited to the comparison of the different particle sizes, dose of exposure, and duration of exposure effects toward cardiotoxicity, and does not compare the different effects of toxicity between different particle types.…”
Get full text
Article -
1148
Distinct roles for intra- and extracellular siderophores during Aspergillus fumigatus infection.
Published 2007-09-01“…Abrogation of extracellular siderophore biosynthesis following inactivation of the acyl transferase SidF or the nonribosomal peptide synthetase SidD leads to complete dependence upon reductive iron assimilation for growth under iron-limiting conditions, partial sensitivity to oxidative stress, and significantly reduced virulence, despite normal germ tube formation. …”
Get full text
Article -
1149
Cardioprotective effects of total and anthocyanin-rich extracts of Opuntia ficus-indica fruit on epinephrine-induced cardiac injury in rats
Published 2024-12-01“…Conclusions: Supplementation with fruit extracts of Opuntia ficus-indica, especially anthocyanin-rich extract, could protect against epinephrine-induced cardiac injury in rats by alleviating electrocardiographic, biochemical, histopathological, and oxidative stress parameters, and may be used in the treatment of cardiovascular diseases.…”
Get full text
Article -
1150
The Protective Effect of Anthocyanins Extracted from Aronia Melanocarpa Berry in Renal Ischemia-Reperfusion Injury in Mice
Published 2021-01-01“…Pretreatment of two weeks resulted in different extent amelioration of renal dysfunction and tubular damage and suppression of proinflammatory cytokines, oxidative stress, lipid peroxidation, and apoptosis, thus suggesting that cyanidins are potentially effective in acute renal ischemia by the decrease of inflammation, oxidative stress, and lipid peroxidation, as well as apoptosis. …”
Get full text
Article -
1151
Synergistic anti-oxidative/anti-inflammatory treatment for acute lung injury with selenium based chlorogenic acid nanoparticles through modulating Mapk8ip1/MAPK and Itga2b/PI3k-AKT...
Published 2025-01-01“…Abstract Oxidative stress and inflammatory dysregulation play crucial roles in pathogenesis of acute lung injury (ALI), and their cyclic synergy drives excessive inflammatory responses and further exacerbates ALI. …”
Get full text
Article -
1152
Effects of High‐Fructose Corn Syrup Addition to Broiler Diets on Performance, Carcass Yield, Visceral Weights, Gut pH and Some Blood Parameters
Published 2024-11-01“…In particular, low‐HFCS supplementation decreased the OSI, indicating that it could possibly reduce oxidative stress. Accordingly, HFCS could be added to broiler diets at a level of 50 mg/kg.…”
Get full text
Article -
1153
Therapeutic Potential of Ginger Ethanolic Extract, Ginger-Loaded Chitosan Nanoparticles, and Chitosan Nanoparticles in Induced Type 2 Diabetes Mellitus in Dogss in Induced Type 2...
Published 2024-12-01“…The results showed that dogs in the diabetic Positive Control group exhibited hyperglycemia, dyslipidemia, liver dysfunction, and elevated oxidative stress markers, underscoring the severe impact of T2DM. …”
Get full text
Article -
1154
Paraoxonase and Arylesterase Activities, Lipid Profile, and Oxidative Damage in Experimental Ischemic Colitis Model
Published 2012-01-01“…All animals were sacrificed on the seventh postoperative day. Oxidative stress marker (malonyldialdehyde, MDA), lipid profile, and paraoxonase (PON-1) and arylesterase activities were determined. …”
Get full text
Article -
1155
Exposure to Air Pollution Exacerbates Inflammation in Rats with Preexisting COPD
Published 2020-01-01“…Lung function, pathology, inflammatory cytokines, oxidative stress, and mucus and collagen production were measured. …”
Get full text
Article -
1156
High glucose induces podocyte ferroptosis through BAP1/SLC7A11 pathway
Published 2025-01-01“…Ferroptosis and oxidative stress were assessed by measuring malondialdehyde (MDA) levels, cystine uptake capacity, and reactive oxygen species (ROS). …”
Get full text
Article -
1157
Explorating the Involvement of Plasma Sestrin2 in Obstructive Sleep Apnea
Published 2019-01-01“…Obstructive sleep apnea (OSA) can lead to serious complications such as coronary heart disease and hypertension due to oxidative stress. Sestrin2 expression is upregulated under conditions of oxidative stress. …”
Get full text
Article -
1158
Comprehensive Insight of Neurodegenerative Diseases and The Role of Neurotoxin Agents — Glutamate
Published 2020-04-01“…Depletion of GSH renders the cell to oxidative stress and ultimately leading to cell death. …”
Get full text
Article -
1159
Cordyceps militaris solid medium extract alleviates lipopolysaccharide-induced acute lung injury via regulating gut microbiota and metabolism
Published 2025-01-01“…The results showed that CMME treatment improved pulmonary injury, reduced inflammatory factors and oxidative stress levels, and decreased macrophage activation and neutrophil recruitment. …”
Get full text
Article -
1160
Can Chronic Nitric Oxide Inhibition Improve Liver and Renal Dysfunction in Bile Duct Ligated Rats?
Published 2015-01-01“…This was corroborated by increased oxidative stress, TNF-α, TGF-1β, and MMP-13 genes overexpression. …”
Get full text
Article