Significance of Persistent Inflammation in Respiratory Disorders Induced by Nanoparticles by Yasuo Morimoto, Hiroto Izumi, Etsushi Kuroda

“…In inhalation studies and instillation studies of nanomaterials, persistent inflammation is composed of neutrophils and alveolar macrophages, and its pathogenesis is related to chemokines such as the cytokine-induced neutrophil chemoattractant (CINC) family and macrophage inflammatory protein-1α and oxidant stress-related genes such as heme oxygenase-1 (HO-1). …”
Get full text

Immuno-enhancing effects of surimi products including functional ingredients in vitro and in vivo zebrafish model by Dong-Hyeon Kim, Heeseob Lee, Hye-Won Yang, You-Jin Jeon

“…FSPs showed the protective effects against hydrogen peroxide (H2O2)-induced oxidative stressed Vero cells and promoted nitric oxide (NO) production in RAW264.7 cells and zebrafish larvae. …”
Get full text

Curcumin mimics of potential chemoprevention with NQO1 induction properties by Dalia R. Aboshouk, Ahmed R. Hamed, Siva S. Panda, Mohamed S. Bekheit, M. Adel Youssef, Adel S. Girgis

“…NAD(P)H quinone oxidoreductase 1 (NQO1) is a xenobiotic metabolizing cytosolic enzyme/protein with important functional properties towards oxidation stress, supporting its ability in detoxification/chemoprotective role. …”
Get full text

ER Stress and Iron Homeostasis: A New Frontier for the UPR by Susana J. Oliveira, Maria de Sousa, Jorge P. Pinto

“…The responsiveness of the ER chaperone calreticulin to both ER and iron-induced oxidative stresses, and its correlation with HH patients’ phenotype, reinforce the interest of dissecting the UPR signaling/iron metabolism crosstalk and points to the potential clinical value of use of pharmacological chaperones in HFE-HH.…”
Get full text

Wpływ czynników środowiskowych na powstawanie chorób układu krążenia – wybrane problemy by Janusz Jerzemowski

“…Environment might be the factor which causes heart disease by: oxidation stress, inflammatory process, induction of coagulation system, dysfunction of autonomic system. …”
Get full text

Estimation of Antioxidant Levels in Saliva and Serum of Chronic Periodontitis Patients with and without Ischemic Heart Disease by Anahita Punj, Santhosh Shenoy, N. Suchetha Kumari, Priyanka Pampani

“…The salivary and serum antioxidants may not follow the same increase or decrease as a result of increased oxidant stress due to disease.…”
Get full text

Estimation of the Postmortem Duration of Mouse Tissue by Electron Spin Resonance Spectroscopy by Shinobu Ito, Tomohisa Mori, Hideko Kanazawa, Toshiko Sawaguchi

“…Therefore, DMPO-AsA∗ signal may be suitable for detecting an oxidation stress tracer from tissue in comparison with other spin adduct signal on ESR spin trap method.…”
Get full text

Green treasures: phytochemical screening and antioxidant potential of freshwater species of Oedogonium, Ulothrix and Mougeotia (Chlorophyceae) by Elsa Shibu Sruthy, Edathiruthi Kottukkal Chandran Baiju

“…The three algal extracts studied appear to contain significant amounts of antioxidants, which might prevent the progression of various oxidative stresses in vitro. To be considered for clinical use in pharmaceutical or nutraceutical industries, extracts must be assessed for their in vivo antioxidant activity.…”
Get full text

Understanding the impacts of dual methionine oxidations in complementarity-determining regions on the structure of monoclonal antibodies by Bo Zhao, Joy Yoon, Bojie Zhang, Youmi Moon, Yue Fu, Yinyin Li, Yunlong Zhao, Hui Xiao, Ning Li

“…In contrast, the methionine (HC Met115) at the VH-VL interface, when subjected to different oxidative stresses, can undergo oxidation with selective stereochemistry. …”
Get full text

Tetrastigma hemsleyanum as a feed additive: modulating gut microbiota for enhancing nutritional transport and growth performance in Jinhua yellow chickens by Chao Lu, Yun Xiang, Kewei Xu, Fengrui Gao, Shaofeng Zhu, Fangfang Lou, Lu Liu, Xin Peng

“…Meanwhile, dietary TH improved the development of duodenum and notably increased the contents of essential amino acids and flavor amino acids, while the serum oxidation stress index as well as abdominal fat deposition were not affected in Jinhua yellow chickens. …”
Get full text

Branched-chain fatty acids from goat milk alleviate ulcerative colitis via the TLR4/NF-κB/NLRP3 pathway by Jiaxin Zhang, Jinjing Zhong, Zhengying Cui, Yu Shen, Yaping Zheng, Yu Zhang, Chaoxin Man, Yanmei Hou, Qianyu Zhao, Yujun Jiang

“…These results show that BCFAs extracted from goat milk can significantly alleviate weight loss in mice, and reduce the disease activity index and the activity of myeloperoxidase while increasing the content of antioxidant enzymes in colon tissue and reducing the oxidation stress response. These data also show that BCFAs can down-regulate the gene and protein expression of the toll-like receptor 4 (TLR4)/ nuclear factor κB p65 (NF-κB p65)/NOD-like receptor thermal protein domain associated protein 3 (NLRP3) signaling pathway, and at the same time significantly reduce the expression of pro-inflammatory factors tumor necrosis factor α (TNF-α), interleukin 1β (IL-1β), and IL-18 in colon tissue, and significantly increase the expression of the anti-inflammatory factor IL-10. …”
Get full text

Active biomonitoring in streams by using multimarker approaches of mussels by T. Ukasha, N.U.H. Faisal, B.K. Adji, A.P. Nugroho

“…The pollution of Code Stream waters harms oxidatively stressed mussels and may endanger human health via the food chain. …”
Get full text

A Randomized Study to Compare the Effects of Once-Weekly Dulaglutide Injection and Once-Daily Glimepiride on Glucose Fluctuation of Type 2 Diabetes Mellitus Patients: A 26-Week Fol... by Huiqin Li, Xiaohua Xu, Jie Wang, Xiaocen Kong, Maoyuan Chen, Ting Jing, Zhiying Zhang, Guoping Yin, Xiaomei Liu, Yun Hu, Lei Ye, Xiaofei Su, Jianhua Ma

“…Once-weekly dulaglutide injection has the same effectiveness as daily glimepiride on lowering blood glucose and decreasing oxidation stress and inflammation and is more effective in controlling glucose fluctuation as compared with glimepiride. …”
Get full text