Protective Effect of Conditioned Medium of Immortalized Human Stem Cells from Exfoliated Deciduous Teeth Against Hair Graying Caused by X-Ray Irradiation via Its Antioxidative Acti... by Yasuhiro Katahira, Eri Horio, Natsuki Yamaguchi, Jukito Sonoda, Miu Yamagishi, Satomi Miyakawa, Fumihiro Murakami, Hideaki Hasegawa, Izuru Mizoguchi, Takayuki Yoshimoto

“…Hair graying is one of the common visible signs of human aging, resulting from decreased or abolished melanogenesis due to the depletion of melanocyte stem cells through excess accumulation of oxidative stress. Cell-free therapy using a conditioned medium (CM) of mesenchymal stem cells has been highlighted in the field of regenerative medicine owing to its potent therapeutic effects with lower regulatory hurdles and safety risk. …”
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Perbedaan Kadar Superokside Dismutase pada Remaja dengan Dismenore Primer dan Tanpa Dismenore Primer by Yanti ., Ermawati ., Eliza Anas

“…Superokside Dismeutase (SOD) is a bioactive ingredient that is known as antioxidants, protecting cells against harmful SOD oxidants (free radicals) SOD convert superoxide anion into hydrogen perokxide and oxygen, often call  as primary defense agains oxidative stress. Primary dysmenorrhoe increased uterine activity or increased uterine contractions cause arteriolar vasospasm resulting in ischemia and lower abdominal  cramping and increased a lots of oxygen produced. …”
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NRF2 Antioxidant Response and Interferon‐Stimulated Genes Are Differentially Expressed in SARS‐CoV‐2‐Positive Young Subjects by Walter Toscanelli, Matteo Fracella, Marta De Angelis, Carolina Scagnolari, Leonardo Sorrentino, Elena Piselli, Maria Elena Marcocci, Fabio Midulla, Enrica Mancino, Raffaella Nenna, Laura Petrarca, Anna Teresa Palamara, Guido Antonelli, Alessandra Pierangeli, Lucia Nencioni

“…ABSTRACT Background Several respiratory viruses, including Severe Acute Respiratory Syndrome‐Coronavirus‐2 (SARS‐CoV‐2), suppress nuclear factor‐E2‐related factor‐2 (NRF2) antioxidant response, generating oxidative stress conditions to its advantage. NRF2 has also been reported to regulate the innate immune response through the inhibition of the interferon (IFN) pathway. …”
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Supplementation with Standardized Green/Black or White Tea Extracts Attenuates Hypertension and Ischemia-Reperfusion-Induced Myocardial Damage in Mice Infused with Angiotensin II by Mario de la Fuente-Muñoz, Marta Román-Carmena, Sara Amor, María C. Iglesias-de la Cruz, Patricia Martorell, Sonia Guilera-Bermell, Reme García Bou, Antonio M. Inarejos-García, Ángel L. García-Villalón, Miriam Granado

“…In the heart, supplementation with both tea extracts attenuated AngII-induced cardiac hypertrophy and reduced ischemia-reperfusion-induced oxidative stress and apoptosis in myocardial tissue. In conclusion, supplementation with WTE or CTE attenuates AngII-induced cardiovascular damage through their anti-inflammatory, antioxidant, and antiapoptotic effects. …”
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Effects of celastrol on the heart and liver galaninergic system expression in a mouse model of Western-type diet-induced obesity and metabolic dysfunction-associated steatotic live... by Nikolina Canová, Jana Šípková, Mahak Arora, Zuzana Pavlíková, Zuzana Pavlíková, Tomáš Kučera, Ondřej Šeda, Tijana Šopin, Tomáš Vacík, Ondřej Slanař

“…Celastrol influenced the gene expression of galanin receptors: it downregulated Galr1 in the heart and upregulated Galr2 in the liver and Galr3 in the heart ventricles, potentially affecting energy metabolism, oxidative stress, and inflammation. Fatostatin suppressed gene expression of all the detected members of the galaninergic system in the heart ventricles, depicting the role of SREBP in this process.ConclusionThese findings suggest that celastrol may beneficially modulate the galaninergic system under obesity and MASLD-to-MASH progression, indicating its potential as a therapeutic agent for disorders associated with metabolic dysfunction.…”
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Size effect-based improved antioxidant activity of selenium nanoparticles regulating Anti-PI3K-mTOR and Ras-MEK pathways for treating spinal cord injury to avoid hormone shock-indu... by Peixin Liu, Xiaodong Liu, Zihao Wu, Kui Shen, Zhaofeng Li, Xiaowei Li, Qifeng Wu, Leung Chan, Zhong Zhang, Yutong Wu, Liwen Liu, Tianfeng Chen, Yi Qin

“…These compounds effectively protected PC-12 cells from oxidative stress-induced cytotoxicity, alleviated mitochondrial dysfunction, reduced apoptosis. …”
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MSC-EXs inhibits uranium nephrotoxicity by competitively binding key proteins and inhibiting ROS production by Xinrui Yang, Jing Liu, Yaru Yin, Luxun Yang, Mingquan Gao, Zifei Wu, Binghui Lu, Shenglin Luo, Weidong Wang, Rong Li

“…They also enhance oxidative stress resistance via modulation of glutathione metabolism, Cysteine and Methionine metabolism signaling pathways. …”
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Nutritional and antioxidative characterization, antimicrobial and sensorial stability of flaxseed powder supplemented mutton patties by Raheel Suleman, Hira Choudhary, Muhammad Waseem, Jaza Maqbl Alshammari, Muhammad Muzamil, Huan Liu, Tariq Ismail, Muhammad Ammar Khan, Muhammad Qamar, Crossby Osei Tutu

“…Oxidative stress and microbial growth deteriorate food quality and cause safety risks. …”
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Ganoderma lucidum spore oil (GLSO), a novel antioxidant, extends the average life span in Drosophila melanogaster by Yi Zhang, Hongfei Cai, Zhu Tao, Cheng Yuan, Zhaojian Jiang, Juyan Liu, Hiroshi Kurihara, Wendong Xu

“…Compared with untreated groups, groups treated with GLSO had significantly longer average and maximum lifespan in both normal conditions and under oxidative stress. The activities of various antioxidant enzymes were measured to determine the antioxidant effect of GLSO. …”
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Identification of RNA Editing Sites Reveals Functional Modifications with the Addition of Methionine to the Daily Rations of Yaks by Shiyu Wu, Xinrui Liu, Yaxin Liu, Shikai Wang, Wei Peng, Ming Zhang, Binglin Yue, Hui Wang, Jikun Wang, Jincheng Zhong, Fang Sun, Yixi Kangzhu, Jiabo Wang

“…Glutathione produced during methionine metabolism can reduce damage to cells caused by oxidative stress. Supplementing restricted amino acids in animals by scientific means will be beneficial to protein synthesis, which will affect the growth and development of animals and will bring huge economic benefits when applied to actual production and life. …”
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Therapeutic and Safety Evaluation of Combined Aqueous Extracts of Azadirachta indica and Khaya senegalensis in Chickens Experimentally Infected with Eimeria Oocysts by J. G. Gotep, J. T. Tanko, G. E. Forcados, I. A. Muraina, N. Ozele, B. B. Dogonyaro, O. O. Oladipo, M. S. Makoshi, O. B. Akanbi, H. Kinjir, A. L. Samuel, T. E. Onyiche, G. O. Ochigbo, O. B. Aladelokun, H. A. Ozoani, V. Z. Viyoff, C. C. Dapuliga, A. A. Atiku, P. A. Okewole, D. Shamaki, M. S. Ahmed, C. I. Nduaka

“…We thus investigated the efficacy and safety of the combined aqueous extracts of these plants for the treatment of experimentally induced coccidiosis in broiler chickens using oocyst count, oxidative stress biomarkers, serum biochemistry, histology, and haematological parameters. …”
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Effect of Acarbose on High Carohydrate Diet Induced Liver Injury in Largemouth Bass (Micropterus salmoides) by Yanhao CAO, Xiaolong BO, Hongli LIU, Xiaoli HUANG

“…【Conclusion】Acarbose can effectively alleviate liver enlargement in largemouth bass caused by high carbohydrate diets, reduce liver to body ratio, alleviate liver cell apoptosis and vacuolization, reduce liver glycogen accumulation, alleviate oxidative stress damage in the body, thus protect the health of largemouth bass. …”
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The Effect of the Concurrent Use of Angiotensin-Converting Enzyme Inhibitors or Receptor Blockers on Toxicity and Outcomes in Patients Treated with Radiotherapy: A Systematic Revie... by Wan-Chuen Liao, Hala Shokr, Corinne Faivre-Finn, Clare Dempsey, Kaye Janine Williams, Li-Chia Chen

“…<b>Background/Objectives</b>: ACEIs protect against radiation pneumonitis by reducing angiotensin II production, oxidative stress, and inflammation. This study highlights the significance of concurrent angiotensin-converting enzyme inhibitor (ACEI) or angiotensin receptor blocker (ARB) use in radiotherapy by evaluating its impact on radiotherapy-related side effects and survival outcomes, addressing the gap in existing research and providing insights to guide clinical practice in oncology. …”
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Repeated social defeat in male mice induced unique RNA profiles in projection neurons from the amygdala to the hippocampus by Rebecca G. Biltz, Wenyuan Yin, Ethan J. Goodman, Lynde M. Wangler, Amara C. Davis, Braedan T. Oliver, Jonathan P. Godbout, John F. Sheridan

“…These DEGs were associated with an increase in oxidative stress, synaptic long-term potentiation, and neuroinflammatory signaling. …”
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Artemisinin supplementation in concentrated cottonseed protein basal diets enhances growth, antioxidant capacity, intestinal immunity and microbiota in hybrid grouper (Epinephelus... by Ling Pan, Qi Wang, Weikang Li, Xiaohui Dong, Shiwei Xie, Beiping Tan, Hongyu Liu, Yan Wang

“…Artemisinin supplementation significantly enhanced the activities of SOD, GSH-Px, CAT, and T-AOC in the liver and hindgut (P < 0.05),while also reducing MDA levels, thereby demonstrating its protective effect against oxidative stress and its ability to strengthen antioxidant defense system. …”
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β2 integrin regulates neutrophil trans endothelial migration following traumatic brain injury by Lei Li, Ruilong Peng, Cong Wang, Xin Chen, Dilmurat Gheyret, Siyu Guan, Bo Chen, Yafan Liu, Xilei Liu, Yiyao Cao, Cha Han, Jianhua Xiong, Fanjian Li, Taoyuan Lu, Haoran Jia, Kaiji Li, Jinchao Wang, Xu Zhang, Jianye Xu, Yajuan Wang, Xin Xu, Tuo Li, Jianning Zhang, Shu Zhang

“…The treatment has demonstrated significant improvements in neurologic function in TBI mice, attenuating blood–brain barrier permeability, mitigating oxidative stress and inflammatory mediator release, and enhancing cerebral perfusion. …”
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Dietary Magnesium Intake and Leukocyte Telomere Attrition in Adults: The Regulatory Role of Serum Tumor Necrosis Factor α by Jie Yu, Haibin Liu, Shuli He, Pingping Li, Chunxiao Ma, Minglei Ma, Yiwen Liu, Lu Lv, Fan Ping, Huabing Zhang, Wei Li, Qi Sun, Lingling Xu, Yuxiu Li

“…Serum blood lipid profile, HbA1c, oxidative stress, and proinflammatory mediator levels were measured. …”
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Tangeretin alleviates sepsis-induced acute lung injury by inhibiting ferroptosis of macrophage via Nrf2 signaling pathway by Hui Zhang, Yan Wang, Shenghua Wang, Xiaomei Xue, Kai Huang, Dunfeng Xu, Lai Jiang, Siyuan Li, Yunqian Zhang

“…The silence of Nrf2 abolished the inhibitory effect of tangeretin on oxidative stress, inflammatory response and ferroptosis in RAW264.7 cells. …”
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Exploring Disparities in Gill Physiological Responses to NaHCO₃-Induced Habitat Stress in Triploid and Diploid Crucian Carp (<i>Carassius auratus</i>): A Comprehensive I... by Shicheng Han, Lin Han, Fangying Yuan, Wenzhi Liu, Jing Wang, Xiaofeng Jin, Yanchun Sun

“…<b>Conclusions</b>: Overall, NaHCO₃-induced stress leads to significant gill tissue damage, accompanied by reactive oxygen species (ROS) production causing oxidative stress and disruptions in lipid metabolism in crucian carp. …”
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Thioredoxin-interacting protein (TXNIP) inhibition promotes retinal ganglion cell survival and facilitates M1-like microglial transformation via the PI3K/Akt pathway in glaucoma by Junjue Chen, Huimin Zhong, Bingqiao Shen, Huan Yu, Yang Zhang, Ruiqi Han, Ping Huang, Shouyue Huang, Yisheng Zhong

“…Thioredoxin-interacting protein (TXNIP) is involved in glucose and lipid metabolism, and associated with oxidative stress and inflammation, however, not known whether to be involved in glaucoma neuropathy and its underlying mechanisms. …”
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