Renoprotective effects of coenzyme Q10 supplementation in patients with chronic kidney disease: a protocol for a systematic review by Hisashi Noma, Takeshi Hasegawa, Hiroki Nishiwaki, Erika Ota, Taihei Suzuki, Yoshitaka Watanabe, Yoshifusa Abe

“…CoQ10 supplementation can improve mitochondrial function and decrease oxidative stress in these patients. This systematic review will assess the renoprotective effects of CoQ10 supplementation in patients with CKD.Methods and analysis We will include the following studies: (1) randomised-controlled trials, (2) participants with CKD and (3) participants treated with CoQ10 as an intervention. …”
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Impact of essential oil and probiotics supplementation on growth performance, serum biomarkers, antioxidants status, bioenergetics and histomorphometry of intestine of Nile tilapia... by Walaa S. Raslan, Ahmed Shehab, Aya F. Matter, Hadeer A. Youssuf, Omar Ahmed Farid, Ahmed Sabek, Yasmeen Magdy, Amgad Kadah

“…Results The results revealed that using probiotics and or essential oils in Nile tilapia diets improved growth performance, reduced oxidative stress, enhanced immunity, maintained intestinal integrity, and enhanced resistance to pathogenic infection (P ≤ 0.05). …”
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Blood Trihalomethanes and Human Cancer: A Systematic Review and Meta-Analysis by Miaomiao Fu, Pengyu Xue, Zhuorong Du, Jingsi Chen, Xiaojun Liang, Jiafu Li

“…Additionally, we discussed the carcinogenic mechanisms of THMs, which involve multiple biological pathways such as oxidative stress, DNA adduct formation, and endocrine disruption, with variations in accumulation and target sites potentially leading to different cancer types, for which evidence is currently lacking. …”
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The Iron-Klotho-VDR Axis Is a Major Determinant of Proximal Convoluted Tubule Injury in Haptoglobin 2-2 Genotype Diabetic Nephropathy Patients and Mice by Inbal Dahan, Nadia Thawho, Evgeny Farber, Nakhoul Nakhoul, Rabea Asleh, Andrew P. Levy, Yan Chun Li, Ofer Ben-Izhak, Farid Nakhoul

“…Hp 2-2 diabetic mice have impaired Hb clearance and increased iron deposits and oxidative stress in the proximal tubules (PCT), leading to increased renal injury. …”
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First-in-Man Evaluation of I-PGN650: A PET Tracer for Detecting Phosphatidylserine as a Biomarker of the Solid Tumor Microenvironment by Richard Laforest PhD, Farrokh Dehdashti MD, Yongjian Liu PhD, Jennifer Frye CMMT, Sarah Frye CMMT, Hannah Luehmann, Deborah Sultan, Joseph S. Shan PhD, Bruce D. Freimark PhD, Barry A. Siegel MD

“…Purpose: PGN650 is a F(ab′) 2 antibody fragment that targets phosphatidylserine (PS), a marker normally absent that becomes exposed on tumor cells and tumor vasculature in response to oxidative stress and increases in response to therapy. …”
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The storage quality and transcriptome analysis of fresh-cut taro by L-ascorbic acid combined with ultrasonic treatment by Lin Chen, Bingzhi Chen, Lulu Chu, Lili Chen, Luyu Xie, Youjin Deng, Yuji Jiang

“…Therefore, we concluded that AS treatment could alleviate oxidative stress and maintain storage quality by regulating metabolic pathways. …”
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Characterization and Otoprotective Effects of Polysaccharides from <i>Arthrospira platensis</i> by Matteo Banti, Mercedes Garcia-Gil, Lorenzo Guidotti, Graziano Di Giuseppe, Simona Rapposelli, Daniela Monti, Silvia Tampucci, Marinella De Leo, Francesca Gado, Paola Nieri, Clementina Manera

“…The recent literature reported that hearing loss is promoted by an excessive generation of reactive oxygen species (ROS) in cochlea cells, which causes oxidative stress. Recently, polysaccharides from the cyanobacterium <i>Arthrospira platensis</i> showed many biological activities, including antioxidant activity, suggesting their potential use to combat hearing loss. …”
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Utilization of edible poultry slaughter residues: A chicken-liver hydrolysate with glucose-lowering ability and upregulating glycogenesis in type II diabetes by Yi-Ling Lin, Yu-Pei Chen, Sheng-Yao Wang, Yi-Feng Kao, Chompunut Lumsangkul, Yi-Chen Chen

“…Additionally, CLH ameliorated (p<0.05) decreased hindlimb-gastrocnemius weight, and liver lipid contents, oxidative stress (sera and liver) and inflammatory cytokines. …”
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A Comparative Analysis of the Antioxidant Profiles Generated by the RoXsta^TM System for Diverse Biological Fluids Highlights the Powerful Protective Role of Human Semina... by Robert J. Aitken, Alexandra Wilkins, Natasha Harrison, Mohammad Bahrami, Zamira Gibb, Kaitlin McIntosh, Quan Vuong, Sarah Lambourne

“…Moreover, comparative studies demonstrated that human SP exhibited significantly (<i>p</i> < 0.001) higher levels of antioxidant potential than any other species examined (stallion, bull, dog) and that this intense activity reflected the relative vulnerability of human spermatozoa to peroxide attack. (4) Conclusions: The RoXsta^TM system provides valuable information on the antioxidant profile of complex biological fluids, supporting its diagnostic role in conditions associated with oxidative stress. Based on the results secured in this study, human semen is identified as a particularly rich source of antioxidants capable of scavenging both hydrogen and organic peroxides, in keeping with the high susceptibility of human spermatozoa to peroxide-mediated damage.…”
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Effects of Tannic Acid Supplementation of a High-Carbohydrate Diet on the Growth, Serum Biochemical Parameters, Antioxidant Capacity, Digestive Enzyme Activity, and Liver and Intes... by Yi Wang, Jianjun Wu, Luoxin Li, Yuanfeng Yao, Chiqing Chen, Yucong Hong, Yi Chai, Wei Liu

“…Finally, it should be noted that, when the dietary TA level exceeded 800 mg/kg, TA appeared to play a pro-oxidation role in the liver, which may cause oxidative stress in the liver.…”
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Zinc Supplementation Prevented Type 2 Diabetes-Induced Liver Injury Mediated by the Nrf2-MT Antioxidative Pathway by Lechu Yu, Yuanyuan Liu, Yichun Jin, Tinghao Liu, Wenhan Wang, Xuemian Lu, Chi Zhang

“…This induced preventive effects on conditions caused by type 2 diabetes like oxidative stress, apoptosis, the subsequent hepatic inflammatory response, fibrosis, hypertrophy, and hepatic dysfunction. …”
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The Effects of Vitamin D on Gentamicin-Induced Acute Kidney Injury in Experimental Rat Model by Ender Hur, Alev Garip, Asuman Camyar, Sibel Ilgun, Melih Ozisik, Sena Tuna, Murat Olukman, Zehra Narli Ozdemir, Eser Yildirim Sozmen, Sait Sen, Fehmi Akcicek, Soner Duman

“…Vitamin D has proven to be effective on renin expression, inflammatory response, oxidative stress, apoptosis, and atherosclerosis. We aimed to investigate the effect of vitamin D in an experimental rat model of gentamicin-induced AKI. …”
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Global bibliometric analysis of traditional Chinese medicine regulating gut microbiota in the treatment of diabetes from 2004 to 2024 by Jieling Liang, Xiaojuan Lin, Xin Liao, Xi Chen, Ying Zhou, Lin Zhang, Yunyun Qin, Haoru Meng, Zhongwen Feng

“…Key identified keywords included obesity, insulin resistance, inflammation, and oxidative stress.ConclusionThree key research focuses in this domain include: the therapeutic effects of active constituents in TCM on diabetes via gut microbiota modulation, the underlying mechanisms through which TCM influences gut microbiota in diabetes management, and the targeted regulation of specific gut bacterial populations by TCM in the treatment of diabetes.…”
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Alcohol promotes CPT1A-induced lipid metabolism disorder to sentinel-regulate acute pancreatitis by Zenghui Li, Xinghui Li, Hui Jiang, Jingdong Li, Bin Xiao, Yong Chen, Shunhai Jian, Mei Zeng, Xiaoming Zhang

“…Etomoxir treatment mitigates the influence of alcohol stimulation on the aberrant expression of proteins associated with oxidative stress, increased ROS production, mitochondrial ultrastructural alterations and mitochondrial dysfunction in AR42J cells. …”
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Antihypertensive effects of whey protein hydrolysate involve reshaping the gut microbiome in spontaneously hypertension rats by Peipei Dou, Xiaoyi Li, Xiaoxiao Zou, Kai Wang, Lei Yao, Zhuo Sun, Hui Hong, Yongkang Luo, Yuqing Tan

“…Notably, WPH alleviated serum oxidative stress, indicated by the decreased malondialdehyde content (P &lt; 0.01), enhanced total antioxidant capacity (P &lt; 0.01) and superoxide dismutase activity (P &lt; 0.01). …”
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Thioredoxin 1 in Prostate Tissue Is Associated with Gleason Score, Erythrocyte Antioxidant Enzyme Activity, and Dietary Antioxidants by Terrence M. Vance, Gissou Azabdaftari, Elena A. Pop, Sang Gil Lee, L. Joseph Su, Elizabeth T. H. Fontham, Jeannette T. Bensen, Susan E. Steck, Lenore Arab, James L. Mohler, Ming-Hui Chen, Sung I. Koo, Ock K. Chun

“…Growing evidence suggests that oxidative stress is involved in prostate cancer. Methods. …”
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Role of Nanotechnology in Ischemic Stroke: Advancements in Targeted Therapies and Diagnostics for Enhanced Clinical Outcomes by Virendra Kumar Yadav, Rachna Gupta, Abdullah A. Assiri, Jalal Uddin, Azfar A. Ishaqui, Pankaj Kumar, Khalid M. Orayj, Shazia Tahira, Ashish Patel, Nisha Choudhary

“…Nanomaterials like cerium oxide (CeO₂) and liposome-encapsulated agents have neuroprotective properties that reduce oxidative stress and promote neuroregeneration. In the present article, the authors have emphasized the significant advancements in the nanomedicine management of stroke, including NPs-based drug delivery systems, neuroprotective and neuroregenerative therapies, and multimodal imaging advancements.…”
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Gut Microbiota as Emerging Players in the Development of Alcohol-Related Liver Disease by Wei Li, Wenkang Gao, Shengqi Yan, Ling Yang, Qingjing Zhu, Huikuan Chu

“…Alcohol-related liver disease develops due to a complex interplay of multiple reasons, including oxidative stress generated during the metabolism of ethanol, immune response activated by immunogenic substances, and subsequent inflammatory processes. …”
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Protective effects of wogonin in the treatment of central nervous system and degenerative diseases by Qingan Fu, Qingyun Yu, Hongdan Luo, Zhekang Liu, Xiaowei Ma, Huijian Wang, Zhijuan Cheng

“…In ischemic stroke models, wogonin reduces infarct size and enhances neurological outcomes by mitigating inflammation and oxidative stress. For patients with hemorrhagic stroke and traumatic brain injury, it accelerates hematoma regression, mitigates secondary brain damage, and promotes neurogenesis, making it an entirely new treatment option for patients with limited access to this type of therapy. …”
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PDE4B promotes ferroptosis in nucleus pulposus cells and is involved in intervertebral disc degeneration by Weixing Xu, Rana Dhar, Danyang Zheng, Qi Peng, Yue Li, Sheng Mei, Huifang Tang

“…Meanwhile, the level of cytokine and oxidative stress were upregulated. Ferroptosis inhibitor Fer-1 or Nrf2 activator dimethyl fumarate (DMF) suppressed the effect of PDE4B-OE, while ferroptosis inducer elastin enhanced the effect of PDE4B-OE. …”
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