Isoproterenol mechanisms in inducing myocardial fibrosis and its application as an experimental model for the evaluation of therapeutic potential of phytochemicals and pharmaceutic... by Lujain Bader Eddin, Mohamed Fizur Nagoor Meeran, Niraj Kumar Jha, Samer N. Goyal, Shreesh Ojha

“…Intraperitoneal or subcutaneous ISP has been widely used in preclinical studies to induce cardiac remodeling manifested by fibrosis and hypertrophy. The induced oxidative stress with subsequent perturbations in cellular signaling cascades through triggering the release of free radicals is considered the initiating mechanism of myocardial fibrosis. …”
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Silica Nanoparticles Loaded With Selenium Quantum Dots Reduce Myocardial Ischemia-Reperfusion Injury by Alleviating Ferroptosis and Mitochondrial Dysfunction by Li T, Yang B, Liu X, Shi D, Wang Z, Chen Y, Shen C

“…Additionally, the effects of Se@PSN on ferroptosis, mitochondrial damage, oxidative stress, and myocardial IR injury severity were evaluated.Results: Se@PSN enhanced the stability of selenium quantum dots and exhibited strong ROS scavenging abilities. …”
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Neuroprotective Effects of the Ethanolic Leaf Extract of Crassocephalum crepidioides (Asteracaeae) on Diazepam-Induced Amnesia in Mice by Beppe Galba Jean, Folefack Alice Irène, Atsamo Albert Donatien, Ngatanko Aïbassou Hervé-Hervé, Barga Mpoo Bertrand, Allah-Doum Nanou Gael, Nguedia Ymele Merline, Zemo Gamo Franklik, Dongmo Alain Bertrand, Dimo Théophile

“…Hippocampi, isolated from the right hemisphere, were used to prepare a homogenate for the determination of oxidative stress biomarkers. The ethanolic leaf extract of cc significantly (p<0.001) decreased the number of working and reference memory errors in the RAM test and induced a significant (p<0.01) increase in the time spent exploring the novel object in the NOR test. …”
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Hypoxic Wharton’s Jelly Stem Cell Conditioned Medium Induces Immunogenic Cell Death in Lymphoma Cells by Hao Daniel Lin, Chui-Yee Fong, Arijit Biswas, Ariff Bongso

“…Hypoxic hWJSC-CM produced a significantly greater reduction in cell viability and a significantly greater increase in apoptosis, oxidative stress, and lipid peroxidation in human lymphoma cells compared to normoxic hWJSC-CM. …”
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Association between Alpha- Klotho Protein, Calcium, and Phosphate concentrations in Adult Iraqi Patients with Beta-Thalassemia Major by Ahmed J. Kadhim, Hedef D. El-Yaseen, Ali M. Jawad

“…Alpha-Klotho protein is a protein that has anti-aging properties and is involved in several functions, including reducing oxidative stress, regulating energy metabolism through several routes, and managing calcium and phosphate metabolism. …”
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Palm Tocotrienol Activates the Wnt3a/β-Catenin Signaling Pathway, Protecting MC3T3-E1 Osteoblasts from Cellular Damage Caused by Dexamethasone and Promoting Bone Formation by Norfarahin Abdullah Sani, Nur Aqilah Kamaruddin, Ima Nirwana Soelaiman, Kok-Lun Pang, Kok-Yong Chin, Elvy Suhana Mohd Ramli

“…<b>Background and aim:</b> Prolonged glucocorticoid (GC) treatment increases oxidative stress, triggers apoptosis of osteoblasts, and contributes to osteoporosis. …”
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Unveiling the mechanism of micro-and-nano plastic phytotoxicity on terrestrial plants: A comprehensive review of omics approaches by Asad Jamil, Ambreen Ahmad, Muhammad Moeen-ud-din, Yihao Zhang, Yuxuan Zhao, Xiaochen Chen, Xiaoyu Cui, Yindong Tong, Xianhua Liu

“…We summarize how MNPs interact with plant cellular structures, disrupt metabolic processes, and induce oxidative stress, ultimately affecting plant growth and productivity. …”
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Genetic Variations and mRNA Expression of NRF2 in Parkinson’s Disease by Caroline Ran, Karin Wirdefeldt, Lovisa Brodin, Mehrafarin Ramezani, Marie Westerlund, Fengqing Xiang, Anna Anvret, Thomas Willows, Olof Sydow, Anders Johansson, Dagmar Galter, Per Svenningsson, Andrea Carmine Belin

“…Nuclear factor erythroid 2-like 2 (NRF2) encodes a transcription factor regulating mechanisms of cellular protection and is activated by oxidative stress. NRF2 has therefore been hypothesized to confer protection against Parkinson’s disease and so far an NRF2 haplotype has been reported to decrease the risk of developing disease and delay disease onset. …”
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Hydroxytyrosol Protects against Myocardial Ischemia/Reperfusion Injury through a PI3K/Akt-Dependent Mechanism by Ying-hao Pei, Jiao Chen, Liang Xie, Xiao-min Cai, Run-Hua Yang, Xing Wang, Jian-bin Gong

“…Myocardial infarct size, markers of oxidative stress, extent of myocardial apoptosis, echocardiographically assessed cardiac function, and expression of Akt and GSK 3β were measured in each group. …”
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Unveiling the potential anticancer activity of Spirulina maxima extract-nanoemulsion through in vitro and in vivo studies by Mohammed Yasser Hussein, Merna Nasr, Veronia Emad, Julie Maged, Portia George, Amina Emad, Abeer Mahmoud Badr, Mehrez E. El-Naggar, Sayeda M. Abdo, Jihan Hussein

“…SMNE also demonstrated efficacy in inhibiting tumor growth in mice with Ehrlich ascites carcinoma, normalizing alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels, and reducing oxidative stress markers such as catalase (CAT) and malondialdehyde (MDA). …”
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Chronic Glucocorticoid-Rich Milieu and Liver Dysfunction by Hernán Gonzalo Villagarcía, Vanesa Sabugo, María Cecilia Castro, Guillermo Schinella, Daniel Castrogiovanni, Eduardo Spinedi, María Laura Massa, Flavio Francini

“…We investigated the impact of chronic hypercorticosteronemia (due to neonatal monosodium L-glutamate, MSG, and treatment) on liver oxidative stress (OS), inflammation, and carbohydrate/lipid metabolism in adult male rats. …”
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Physiological and intestinal microbiota responses of sea cucumber Apostichopus japonicus to various stress and signatures of intestinal microbiota dysbiosis by Liang Cui, Yumeng Xie, Kai Luo, Mingyang Wang, Longzhen Liu, Longzhen Liu, Changlin Li, Xiangli Tian

“…Results demonstrated that all stress led to reduced growth performance and digestive capacity of sea cucumber, along with varying degrees of oxidative stress and immune responses. Various stresses significantly altered the diversity, community structure (except for crowding stress), and composition of intestinal microbiota. …”
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Radioprotective Effects of Vitis vinifera L. Seed against Radiation-Induced Short-Term Memory Loss in Young Adult Wistar Rats by Ayomide Abe, Fatai Balogun, Olugbenga Ayannuga

“…This issue primarily arises from ionizing radiation generating reactive oxygen species, contributing to chronic oxidative stress that can damage brain cells. While dose fractionation, intensity-modulated radiotherapy, and neural stem cell transplantation have demonstrated limited effectiveness, natural plant antioxidants offer a promising alternative. …”
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Notoginsenoside R1 Attenuates H/R Injury in H9c2 Cells by Maintaining Mitochondrial Homeostasis by Yuanbo Xu, Piao Wang, Ting Hu, Ke Ning, Yimin Bao

“…Mitochondrial homeostasis is crucial for maintaining cellular energy production and preventing oxidative stress, which is essential for overall cellular function and longevity. …”
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Correlation between MDA Level and Chitotriosidase-1 Activity in Seminal Fluid of Iraqi Infertile Males by Ali S. Abdul Aziz, Hedef D. Elyaseen, Hussain K. Kadhem

“…On the other hand, malondialdehyde is a marker of lipid peroxidation, reflecting oxidative stress levels. Objective: This study aimed to explore the correlation between malondialdehyde levels and Chitotriosidase-1in seminal fluid in Iraqi infertile males. …”
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Protective Role of Picralima nitida Seed Extract in High-Fat High-Fructose-Fed Rats by Opeyemi Christianah De Campos, Daniel Ikpomwosa Osaigbovo, Titilayo Ifeoluwa Bisi-Adeniyi, Franklyn Nonso Iheagwam, Solomon Oladapo Rotimi, Shalom Nwodo Chinedu

“…This study examined the potential palliative effect of aqueous seed extract of Picralima nitida (APN) on dyslipidemia, hyperglycemia, oxidative stress, insulin resistance, and the expression of some metabolic genes in high-fat high-fructose-fed rats. …”
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The Effect of Taxifolin on Cisplatin-Induced Pulmonary Damage in Rats: A Biochemical and Histopathological Evaluation by Edhem Unver, Mustafa Tosun, Hasan Olmez, Mehmet Kuzucu, Ferda Keskin Cimen, Zeynep Suleyman

“…These histopathological findings demonstrate that taxifolin provides protection against pulmonary oxidative stress by preventing increases in oxidant parameters and decreases in antioxidants.…”
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Identification and Verification of Hub Mitochondrial Dysfunction Genes in Osteoarthritis Based on Bioinformatics Analysis by Hui Niu, Xingxing Deng, Qian Zhang, Yijun Zhao, Jinfeng Wen, Wenyu Li, Huan Liu, Xiong Guo, Cuiyan Wu

“…Age-related mitochondrial dysfunction and associated oxidative stress may contribute to the development of osteoarthritis. …”
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HPV16E6-Dependent c-Fos Expression Contributes to AP-1 Complex Formation in SiHa Cells by Feixin Liang, Shinichiro Kina, Hiroyuki Takemoto, Akira Matayoshi, Thongsavanh Phonaphonh, Nao Sunagawa, Keiichi Arakaki, Akira Arasaki, Hai Kuang, Hajime Sunakawa

“…Here, we show that HPV16E6-dependent c-fos oncogenic protein expression contributes to AP-1 complex formation under oxidative stress in SiHa cells (HPV16-positive squamous cell carcinoma of the cervix). …”
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A Cross-Sectional Trait Versus State Biomarker Analysis of Inflammatory Cytokines and miRNAs in Patients with Major Depressive Disorder by Christopher Rockson, Chandrashekaran Girish, Harivenkatesh Natarajan, Vikas Menon

“…We aimed to assess and compare selected cytokines, miRNAs, and oxidative stress biomarker levels between patients with MDD, first-degree relatives (FDRs), and unrelated healthy controls (UHCs). …”
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