Psoralidin: emerging biological activities of therapeutic benefits and its potential utility in cervical cancer by Tanya Tripathi, Apoorva Chaudhary, Divya Janjua, Udit Joshi, Nikita Aggarwal, Chetkar Chandra Keshavam, Alok Chandra Bharti

“…Psoralidin carries out its anti-cancer activity by inducing oxidative stress, autophagy, and apoptosis. This unique characteristic suggests its potential to be used as an adjunct molecule in combination with existing treatment to enhance the efficacy of chemo/radiotherapy for treating CaCx. …”
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Complex immunotoxic effects of T-2 Toxin on the murine spleen and thymus: Oxidative damage, inflammasomes, apoptosis, and immunosuppression by Mingyan Chen, Yanfang Zhang, Yangbo Zhao, Kewei Cao, Ruiyan Niu, Dongguang Guo, Zilong Sun

“…The key mechanisms identified include oxidative stress, activation of the NLRP3 inflammasome, apoptosis, and mitochondrial dysfunction. …”
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Effect of cubebin against streptozotocin-induced diabetic nephropathy rats via inhibition TNF-α/NF-κB/TGF-β: in vivo and in silico study by Rahamat Unissa Syed, Sivakumar S. Moni, Weiam Hussein, Taghreed Mohammad Saad Alhaidan, Sondos Mohammed Y. Abumilha, Lama Khalid Alnahdi, Ling Shing Wong, Vetriselvan Subramaniyan, Vinoth Kumarasamy

“…Biochemical parameters such as glucose levels, kidney parameters, lipid profile, oxidative stress, endogenous antioxidant markers, inflammatory cytokines and histopathology were performed. …”
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Exploring the Antioxidant and Neuroprotective Potential of Muscari armeniacum: Phenolic Profiling and Enzyme Inhibition by Fevzi Topal, Firat Yılmaz, Meryem Topal, Ahmed Menevşeoğlu

“…Its potential applications in the treatment of oxidative stress-related diseases and neurodegenerative disorders make it a promising candidate for further pharmacological studies. …”
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Safety and efficacy of omaveloxolone v/s placebo for the treatment of Friedreich's ataxia in patients aged more than 16 years: a systematic review by Ankita Umrao, Monika Pahuja, Nabendu Sekhar Chatterjee

“…Nrf2 is a regulator of FXN, which is a modulator of oxidative stress in animals and humans. Omaveloxolone (Omav) is an Nrf2 activator and has been reported to have antioxidative potential in various disease conditions. …”
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Discovery of Quinazolone Pyridiniums as Potential Broad-Spectrum Antibacterial Agents by Jie Dai, Qianyue Li, Ziyi Li, Zhonglin Zang, Yan Luo, Chenghe Zhou

“…In addition, the little effect of molecule <b>19a</b> on the production of reactive oxygen species indicated that bacterial death was not caused by oxidative stress. The above comprehensive analyses highlighted the large potential of quinazolone pyridiniums as multitargeting broad-spectrum antibacterial agents.…”
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Empagliflozin-Metformin Combination Has Antioxidative and Anti-Inflammatory Properties that Correlate with Vascular Protection in Adults with Type 1 Diabetes by Miodrag Janić, Matej Cankar, Jan Šmid, Alenka France Štiglic, Aleš Jerin, Mišo Šabovič, Andrej Janež, Mojca Lunder

“…At inclusion and after 12 weeks of treatment, the blood samples were collected, and the oxidative stress (total antioxidative status (TAS), superoxide dismutase (SOD), glutathione peroxidase (GPx), uric acid, advanced oxidation protein products (AOPP), advanced glycosylation end products ((AGE) and isoprostane), and inflammation (C-reactive protein (CRP) and interleukin-6 (IL-6)) parameters were determined. …”
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The Promising Key Factors Mediating Secondary Neuronal Damage in the Perihematomal Region of Intracerebellar Hemorrhage of Mice by Saandeep Bhatia, Ramissh Paramasivam, Mohd Khairul Izamil Bin Zolkefley, Regunath Kandasamy, Sangu Muthuraju, Jafri Malin Abdullah

“…Perihaematoma samples were collected to study morphological changes, immunohistochemistry, nitric oxide (NO) estimation, and oxidative stress markers, respectively. Mouse behavior was disturbed following ICbH on days 3 and 7 compared to the control. …”
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Recent Trends in the Development and Application of Nano-Antioxidants for Skin-Related Disease by Yi Xue, Tao Wang, Ji-Peng Liu, Qi Chen, Xiao-Long Dai, Min Su, Yu-Hang Cheng, Cheng-Chao Chu, Yun-Qing Ren

“…In addition, an imbalance of oxidative stress and antioxidant mechanisms can lead to skin-related diseases. …”
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Guanosine enhances the bactericidal effect of ceftiofur sodium on Streptococcus suis by activating bacterial metabolism by Yue Dong, Xiaona Liu, Shanshan Xiong, Mingyu Cao, Haojie Wu, Long Chen, Mengmeng Zhao, Yadan Zheng, Zhiyun Zhang, Yanyan Liu, Yanhua Li, Qianwei Qu, Chunliu Dong

“…In addition, the function of the cell membrane is affected by guanosine and the accumulation of antimicrobials in the bacteria increased. Bacterial-oxidative stress and DNA damage induced by guanosine is also one of the mechanisms by which the antibacterial effect is enhanced. …”
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Ishophloroglucin A Isolated from <i>Ishige okamurae</i> Protects Glomerular Cells from Methylglyoxal-Induced Diacarbonyl Stress and Inhibits the Pathogenesis of Diabetic Nephropath... by Chi-Heung Cho, Min-Gyeong Kim, Bomi Ryu, Sang-Hoon Lee

“…IPA protected cells from MGO-induced oxidative stress by inhibiting intracellular MGO accumulation (untreated cells: 1.62 μg/mL, MGO treated cells: 25.27 μg/mL, and IPA 5 μM: 11.23 μg/mL) (<i>p</i> < 0.001) and AGE generation and inhibited MGO-induced renal cell damage via the downregulation of MGO-induced RAGE protein expression (relative protein expression levels of MGO treated cells: 9.37 and IPA 5 μM:1.74) (<i>p</i> < 0.001). …”
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Alteration of fecal microbiome and metabolome by mung bean coat improves diet-induced non-alcoholic fatty liver disease in mice by Dianzhi Hou, Jian Tang, Meili Huan, Fang Liu, Sumei Zhou, Qun Shen

“…Results showed that MBC could effectively alleviative the obese phenotype, reduce the lipid accumulation and insulin resistance, and improve the hepatic oxidative stress and inflammatory response. Furthermore, MBC significantly prevented the HFD-induced changes in the structure and composition of gut microbiota, characterized by promoting the bloom of Akkermansia, Lachnospiraceae_NK4A136_group, and norank_f_Muribaculaceae, and along with the elevated short-chain fatty acids concentrations. …”
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Biochemical, Antioxidant, and Antimicrobial Profiling of Essential Oils of Indian Origin for Culinary Applications by K. Sathish Kumar, S. Visnuvinayagam, G. Teena, K. Elavarasan, J. Bindu, Amjad K. Balange, R. Sivaranjani, L. Narasimhamurthy

“…Based on the antioxidant assays, clove EO exhibited the strongest antioxidant activities in both DPPH 70.84±3.95% and FRAP (142.29±1.05 μ mol Fe (II) g−1) even at 5% level, suggesting its potential to inhibit lipid peroxidation, a process linked to oxidative stress in food. The antimicrobial study demonstrated the potential of EOs against foodborne pathogens, particularly against methicillin-resistant S. aureus (MRSA), which reveals their potential against multidrug-resistant bacteria. …”
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Similarities and differences in physiological adaptation to cadmium interactions with nitrogen levels between two aquatic iris life forms in urban wetlands by Zhenzuo Lei, Yuan Jiang, Yanqiong Meng, Yiyong Li, Yucong Li, Tao Hu, Yanjun Ma

“…These findings suggest that evergreen and deciduous irises employ distinct adaptive strategies to Cd toxicity; evergreen irises mitigate oxidative stress through enhanced reactive oxygen species (ROS) scavenging, whereas deciduous irises dilute Cd toxicity by increasing biomass. …”
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Stress-Induced Premature Senescence or Stress-Induced Senescence-Like Phenotype: One In Vivo Reality, Two Possible Definitions? by Olivier Toussaint, Patrick Dumont, Jose Remacle, Jean-Francois Dierick, Thierry Pascal, Christophe Frippiat, Joao Pedro Magalhaes, Stephanie Zdanov, Florence Chainiaux

“…Irreversible growth arrest after exposure to oxidative stress and generation of DNA damage could be as efficient in avoiding immortalisation as “telomere-dependent” replicative senescence. …”
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Bredemolic Acid Ameliorates Selected Liver Function Biomarkers in a Diet-Induced Prediabetic Rat Model by Akinjide Moses Akinnuga, Angezwa Siboto, Bongiwe Khumalo, Ntethelelo Hopewell Sibiya, Phikelelani Ngubane, Andile Khathi

“…However, the administration of BA decreased liver enzyme concentrations, decreased hepatic oxidative stress, and improved antioxidant enzymes such as SOD and GPx. …”
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The Protective Effect of Beraprost Sodium on Diabetic Cardiomyopathy through the Inhibition of the p38 MAPK Signaling Pathway in High-Fat-Induced SD Rats by Jie Li, Li Peng, Hong Du, Yangtian Wang, Bin Lu, Yixin Xu, Xiaozhen Ye, Jiaqing Shao

“…After 8 weeks, we explored the role of the p38 MAPK signaling pathway in inflammation, oxidative stress, cardiac morphology, and myocardial apoptosis. …”
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Next generation thiazolyl ketone inhibitors of cytosolic phospholipase A2 α for targeted cancer therapy by Felicity J. Ashcroft, Asimina Bourboula, Nur Mahammad, Efrosini Barbayianni, Astrid J. Feuerherm, Thanh Thuy Nguyen, Daiki Hayashi, Maroula G. Kokotou, Konstantinos Alevizopoulos, Edward A. Dennis, George Kokotos, Berit Johansen

“…Our findings imply cPLA2α may support cancer by mitigating oxidative stress and inhibiting tumor suppressor expression and suggest that AVX420 has potential for treating acute leukemias and other cancers that are susceptible to oxidative cell death.…”
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Solanum virginianum mediated green nanoparticles to control dental pathogens by Samrin Barkath Akbar Basha, Ranjani Soundhararajan, Hemalatha Srinivasan

“…Based on exploring the mechanism of action of nanoparticles it was observed that SVAgNPs targets dental pathogens more effectively than the antibiotics by inducing the leakage of cellular macromolecules and causing oxidative stress to the bacterial cells. This is the first report on SVAgNPs incorporated dentures controlling the biofilm formation of Enterococcus faecalis and Streptococcus mutans more effectively than ampicillin. …”
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The effect of β-carotene supplementation above requirement on the production and reproduction performance of female sheep and goats - A mini review by Osman Ahmed, Abubeker Hassen, Khoboso Lehloenya

“…The high rate of metabolic activity during breeding, pregnancy, parturition and lactation may lead to oxidative stress in sheep and goats. Antioxidant supplementation is proposed as a therapy for encountering resultant stress. …”
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