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2041
Histopathological effects of hypervitaminosis-D and the protective role of fetuin-A in renal, hepatic, and cardiac tissues in a murine model
Published 2025-01-01“…Fetuin-A provided statistically significant protection against vitamin D-induced damage, reducing oxidative stress and calcification in affected organs. …”
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2042
Advancing Alzheimer's Therapy: Computational strategies and treatment innovations
Published 2025-06-01“…Computational models elucidate the interplay between oxidative stress and neurodegeneration, offering insights into potential therapeutic interventions. …”
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2043
Mitochondrial Thioredoxin-Glutathione Reductase from Larval Taenia crassiceps (Cysticerci)
Published 2010-01-01“…The enzyme was able to protect glutamine synthetase from oxidative inactivation, suggesting that mTGR is competent to contend with oxidative stress.…”
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2044
Antioxidant and anti–inflammatory effects of Helichrysum plicatum DC. subsp. plicatum extract in an experimental model of acute urolithiasis
Published 2025-01-01“…The study analyzed plasma concentrations of thiobarbituric acid reactive substances (TBARS), an indicator of serum oxidative stress (OS), HP, and HP levels. Additionally, oxalate (Ox), urea, calcium, and creatinine clearance levels were measured in both blood and urine, and routine histological evaluations were conducted. …”
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2045
Dietary Capsaicin Supplementation Mitigates Calving-Induced Stress and Enhances Antioxidant Capacity, Immune Function, and Gut Microbiota in Periparturient Dairy Cows
Published 2024-12-01“…These findings suggest that dietary capsaicin supplementation during the transition period improves lactation performance and supports immune function, as well as alleviates oxidative stress. This study highlights the potential of capsaicin as a practical dietary strategy for enhancing productivity in dairy farming.…”
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2046
Preterm nutrition and brain development
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2047
5.6% lidocaine aerosol anesthesia for supragingival ultrasonic scaling in patients with chronic periodontitis or dental plaque-induced gingivitis
Published 2025-01-01“…Additionally, the relationship between periodontal treatment and the reduction of oxidative stress markers in these patients was assessed. …”
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2048
Fatty Acid Accumulation and Resulting PPARα Activation in Fibroblasts due to Trifunctional Protein Deficiency
Published 2012-01-01“…These novel findings suggest that the fatty acid accumulation and the resulting PPARα activation are major causes of the increase in the β-oxidation ability as probable compensation for fatty acid metabolism in the patients’ fibroblasts, and that enhanced cell proliferation and increased oxidative stress due to the PPARα activation relate to the development of specific clinical features such as hypertrophic cardiomyopathy, slight hepatomegaly, and skeletal myopathy. …”
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2049
Oxidant-Antioxidant Balance during On-Pump Coronary Artery Bypass Grafting
Published 2014-01-01“…Serum total oxidant status (TOS), total antioxidant status (TAS), and oxidative stress index (OSI) values were assessed preoperatively, at 20 minutes after aortic clamping and at 30 minutes, 6 hours, and 48 hours after declamping (reperfusion). …”
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2050
Serum biochemical profile in case of cardiorenal syndrome in cats with hypertrophic cardiomyopathy
Published 2024-12-01“…Biochemical tests in animals with feline cardiorenal syndrome verified cytolysis of cardiomyocytes (increased serum activity of lactate dehydrogenase by 2.69 times, creatine phosphokinase by 2.02 times, increased serum concentration of cardiac troponin by 5.20 times as compared to healthy animals), azotemia (increased concentration in serum creatinine by 2.72 times, urea by 2.94 times, symmetric dimethylarginine by 2.60 times and cystatin C by 1.90 times as compared to healthy animals), enhanced ketogenesis, systemic inflammatory process (increased serum concentration of C-reactive protein by 1.55 times as compared to healthy animals), hypercholesterolemia, oxidative stress (decrease in serum activity of superoxide dismutase by 1.63 times, catalase by 4.67 times and glutathione peroxidase by 1.71 times, increase in the concentration of malondialdehyde by 1.79 times, ceruloplasmin by 2.50 times and diene conjugates by 1.85 times as compared to healthy animals), electrolyte imbalance in the form of hyperkalemia, hyponatremia, hyperphosphatemia and hypomagnesemia. …”
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2051
Antiamnesic and Neurotrophic Effects of Parkia biglobosa (Jacq.) R. Br (Fabaceae) Aqueous Extract on In Vivo and In Vitro Models of Excitotoxicity
Published 2025-01-01“…Scopolamine induced memory impairment and increased oxidative stress, neuroinflammation, and neuronal loss. …”
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2052
Vitamin B12 and diabetic neuropathies
Published 2024-11-01“…Most studies have identified the contribution of low-grade chronic inflammation (LGCI) and oxidative stress (OS) to the development of DN. Immunohistochemical studies of calf muscle nerve biopsies obtained from patients with diabetes mellitus and DN indicate activation of the LGCI pathway caused by increased levels of advanced glycation end products, which leads to increased OS. …”
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2053
The interaction between sleep patterns and oxidative balance scores on the risk of cognitive function decline: Results from the national health and nutrition examination survey 201...
Published 2024-01-01“…Oxidative balance score (OBS) was calculated based on 20 oxidative stress exposures related to diet and lifestyle factors, with higher scores indicating greater antioxidant exposures. …”
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2054
Modified citrus pectin ameliorates methotrexate-induced hepatic and pulmonary toxicity: role of Nrf2, galectin-3/TLR-4/NF-κB/TNF-α and TGF-β signaling pathways
Published 2025-01-01“…Moreover, MCP minimized oxidative stress elicited by MTX in lung and liver tissues, as indicated by reduced malondialdehyde levels, elevated levels of reduced glutathione, increased superoxide dismutase activity, and upregulated Nrf2 protein expression. …”
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2055
Global hotspots and trends of nutritional supplements for sick populations from 2000 to 2024
Published 2025-01-01“…Research focuses on dietary supplementation, oxidative stress, in vitro injections, development, antioxidant activity, double-blind trials, lipid supplements, functional foods, the health of diseased populations, and the risks of NS.ConclusionDifferent supplements each possess unique benefits and should be chosen according to the type of disease to ensure they contain the corresponding nutrients. …”
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2056
Mechanism of TGIF1 on glycolipid metabolism disorders in mice with type 2 diabetes
Published 2025-01-01“…Liver function and oxidative stress were measured. Palmitic acid (PA)-induced primary hepatocytes were used to establish cell models. …”
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2057
Bacillus coagulans alleviates hepatic injury caused by Klebsiella pneumoniae in rabbits.
Published 2025-01-01“…<h4>Conclusion</h4>Above data indicate that BC supplementation effectively attenuated oxidative stress and inflammatory response induced by KP through augmenting the activities of antioxidant enzymes and diminishing the levels of pro-inflammatory factors. …”
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2058
Antioxidant, Anti-α-Glucosidase, Anti-Tyrosinase, and Anti-Acetylcholinesterase Components from Stem of <i>Rhamnus formosana</i> with Molecular Docking Study
Published 2024-12-01“…These findings suggest that bioactive extracts and compounds from the stems of <i>R. formosana</i> may have potential as natural antioxidant, anti-α-glucosidase, anti-AChE, and anti-tyrosinase drug candidates or dietary supplements for the management of oxidative stress-related conditions, including hyperglycemia, pigmentation disorders, and neurodegenerative diseases.…”
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2059
Comprehensive Analysis of Transcriptome Sequencing Data in the Lung Tissues of COPD Subjects
Published 2015-01-01“…Although airway inflammation and oxidative stress are known to be important in the pathogenesis of COPD, the mechanism underlying airflow obstruction is not fully understood. …”
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2060
Structural Characterization of Polygonum divaricatum L. Polysaccharide and Its Inhibitory Effect on Lipopolysaccharide-Induced Inflammation in RAW264.7 Cells
Published 2024-12-01“…PSPDL inhibited the release of inflammatory factors and related gene mRNA expression, ameliorated oxidative stress, down-regulated the protein expression levels of p38, p-p38, IκB-α, p65, and p-p65. …”
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