The Dose Makes the Poison: Sugar and Obesity in the United States – a Review by Samir Faruque, Janice Tong, Vuk Lacmanovic, Christiana Agbonghae, Dulce M Minaya, Krzysztof Czaja

“…Two-thirds of the US population is either overweight or obese. Obesity is one of the major drivers of preventable diseases and health care costs. …”
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Forskolin Inhibits Lipopolysaccharide-Induced Modulation of MCP-1 and GPR120 in 3T3-L1 Adipocytes through an Inhibition of NFκB by Jeanne Durendale Chiadak, Tatjana Arsenijevic, Kevin Verstrepen, Françoise Gregoire, Nargis Bolaky, Valérie Delforge, Véronique Flamand, Jason Perret, Christine Delporte

“…The aim of this study was to determine the signaling pathway by which Forskolin (FK), a cyclic adenosine monophosphate- (cAMP-) promoting agent causing positive changes in body composition in overweight and obese adult men, affects MCP-1 and GPR120 expression during an inflammatory response induced by lipopolysaccharide (LPS) in adipocytes, such as in an obese state. 3T3-L1 cells differentiated into adipocytes (DC) were stimulated with LPS in the absence or presence of FK and inhibitors of TLR-4 and inhibitor of kappa B (IκBα). …”
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Factors Related to Diet Quality in Adolescent at Yadika 12 High School Depok by Zahra Fadhlina Hidayat, Avliya Quratul Marjan, Utami Wahyuningsih

“…Depok has the highest prevalence of overweight adolescents in Indonesia. Data shows an increase in the consumption of high-fat and high-sodium foods. …”
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The Relationship between Body Mass Index and the Severity of Coronary Artery Disease in Patients Referred for Coronary Angiography by Anne B. Gregory, Kendra K. Lester, Deborah M. Gregory, Laurie K. Twells, William K. Midodzi, Neil J. Pearce

“…Patients were grouped into 3 BMI categories: normal (18.5–24.9 kg/m2), overweight (25.0–29.9 kg/m2), and obese (≥30 kg/m2); and multivariable adjusted hazard ratios for 1-year all-cause and cardiac-specific mortality were calculated. …”
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Uncontrolled Hypertension and Behavioral Risk Factors among Adult Hypertensive Patients at Saint Paul’s Hospital, Millennium Medical College, Addis Ababa, Ethiopia by Yemisirach Sisay, Hana Abera, Tolesa Diriba Biratu, Tesfaye Girma Legesse

“…Hypertensive patients from urban areas, those who did not engage in physical activity, and those who were overweight had uncontrolled hypertension odds that were 0.55, 0.43, and 0.25 (AOR and 95% CI) times lower, respectively. …”
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Serum Carboxy-terminal Cross-linking Telopeptide Fragments of Type-2 Collagen Level in the General Population: A Pilot Study by Rajat Khanna, Divyam Jindal, Sudhir Singh

“…The CTX-II value in the underweight category was 365.55 ± 197.09 pg/ml; in the normal body mass index (BMI) category, it was 404.58 ± 225.29 pg/ml; in the overweight category, the BMI was 392.99 ± 193.79 pg/ml; and in obese BMI category, the value was 417.32 ± 186.79 pg/ml. …”
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The Effect of Nutritional Mobile Apps on Populations With Cancer: Systematic Review by Krystal Lu Shin Ng, Murallitharan Munisamy, Joanne Bee Yin Lim, Mustafa Alshagga

“…Most studies focused on breast cancer (6/13, 46%), overweight (6/13, 46%), and survivors (9/13, 69%). Data on anthropometry and body composition (7/13, 54%; 387 participants), nutritional status (3/13, 23%; 249 participants), dietary intake (7/13, 54%; 352 participants), and quality of life (6/13, 46%; 384 participants) were gathered. …”
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Understanding the Relationship between Atherogenic Index of Plasma and Cardiovascular Disease Risk Factors among Staff of an University in Malaysia by Myat Su Bo, Whye Lian Cheah, Soe Lwin, Tin Moe Nwe, Than Than Win, Myint Aung

“…Nearly 80% of the respondents were overweight and obese, 87.1% with high and very high body fat, and 46.9% with abnormal visceral fat. …”
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Quetiapine-related weight loss: Report of a rare adverse effect by Nicodemus Okwudili K Obayi, David HN Nweke, Edidiong Idio, Darlington Okey, Cletus Ozibo

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Prevalence of Hypertension, Obesity, Diabetes, and Metabolic Syndrome in Nepal by Sanjib Kumar Sharma, Anup Ghimire, Jeyasundar Radhakrishnan, Lekhjung Thapa, Nikesh Raj Shrestha, Navaraj Paudel, Keshar Gurung, Maskey R, Anjali Budathoki, Nirmal Baral, David Brodie

“…Results. 34% of the participants had hypertension, and 6.3% were diabetic. 28% were overweight, and 32% were obese. 22.5% of the participants had metabolic syndrome based on IDF criteria and 20.7% according to the NCEP definition. …”
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Does Pre-existing Diabetes Correlate with Long COVID-19 in Europe? Evidence from the Analysis of the Survey of Health, Ageing and Retirement in Europe’s Corona Surveys by Sarah Cuschieri, Piotr Wilk

“…This relationship remained significant (OR=2.00; 98% CI=0.25,1.14) after adjusting for sex (OR=1.64 for females; 95% CI=1.43,1.88), hospitalization for COVID-19 illness (OR=3.19; 95% CI=2.41,4.23), pre-existing hypertension (OR=1.17; 95% CI=1.01,1.36), and overweight (OR=1.31; 95% CI=1.11,1.56) and obese (OR=1.77; 95% CI=1.44,2.19) weight status. …”
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Visceral obesity augments prescription use: An analysis of the cross-sectional study of NHANES 2011-2018. by Maximino Acevedo-Fernández, Renata Ochoa Precoma, Leonardo M Porchia, Victor M Posadas, Enrique Torres-Rasgado, M Elba Gonzalez-Mejia, Esther López-Bayghen

“…However, when stratified by BMI, normal weight participants (ORmetabolic = 10.4; 95%CI: 6.5-16.6 & ORcardiovascular = 7.0; 95%CI: 4.4-11.1, p<0.001) had a greater risk than the overweight (ORmetabolic = 4.1; 95%CI: 3.0-5.6 & ORcardiovascular = 3.4; 95%CI: 2.5-4.7, p<0.001) or obese participants (ORmetabolic = 3.5; 95%CI: 2.3-5.3 & ORcardiovascular = 3.5; 95%CI: 2.5-4.9, p<0.001).…”
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IL1RN and KRT13 Expression in Bladder Cancer: Association with Pathologic Characteristics and Smoking Status by Thomas S. Worst, Verena Reiner, Ute Gabriel, Christel Weiß, Philipp Erben, Thomas Martini, Christian Bolenz

“…Tobacco smoking may enhance the loss of IL1RN, indicating an overweight of proinflammatory mediators involved in UCB progression. …”
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Developing incisional hernia after open liver resection and liver transplantation: A single-center risk factor analysis by Saeed Aldarwish, Paula Guda, Mark Philipp, Clemens Schafmayer, Sebastian Hinz

“…The most important preoperative risk factors were the positive past medical history of other hernias (P = 0.05) and overweight/ obesity (P = 0.018). From the operative course, many risk factors were detected, like an intraoperative blood loss of > 1,000 ml (P = 0.043) and an intraoperative blood transfusion of > 10 PRBCs (P = 0.001), a Mercedes-star incision (P = 0.007), the use of Vicryl (polyglactin 910) sutures and interrupted suture techniques for the fascial reconstruction (P = 0.045) and (P = 0.006), and a long operative time of > 240 min (P = 0.033). …”
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Body size estimation and weight management practices in urban poor communities in Ghana: A cross-sectional study by Grace Agyemang FREMPONG, John K. ANARFI, Delali Margaret BADASU, Samuel Nii Ardey CODJOE

“…Results: More than half (57%) of the total sample was overweight or obese and 56.7% of the participants accurately estimated their body size. …”
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Influencing factors of pain during ultrasound-guided puncture sclerotherapy for ovarian endometriotic cysts via transabdominal and transvaginal approaches by LI Yuanhua, TIAN Hongju, YANG Qian

“…During needle insertion and displacement, particular attention should be given to the overweight patients and those with a history of dysmenorrhea, and appropriate pain intervention measures should be formulated. …”
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Undergraduates' lifestyle and Suboptimal Health Status (SHS): A cross-sectional study in the Ha'il region of Saudi Arabia. by Bandar Alsaif, Collins Otieno Asweto, Sehar-Un-Nisa Hassan, Mohamed Ali Alzain, Mohammed Elshiekh Saeed, Ahmed Kassar, Kamal Elbssir Mohammed Ali, Mouna Ghorbel, Rafat Zrieq, Wei Wang

“…The prevalence of SHS was statistically higher among younger and those studying social science discipline, overweight, had poor diets, engaged in low physical activity, and slept <6 hours (p<0.001). …”
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Effectiveness of Ascophyllum nodosum and Fucus vesiculosus on Metabolic Syndrome Components: A Real-World, Observational Study by Antonio Nicolucci, Maria Chiara Rossi, Massimiliano Petrelli

“…Gdue is a nutraceutical obtained from the association of two marine algae, Ascophyllum nodosum and Fucus vesiculosus, in addition to chromium picolinate, which could be useful for the treatment of dysglycemia, overweight, and the other components of the metabolic syndrome. …”
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Assessment of Weight Management Practices among Adults in the United Arab Emirates by Amita Attlee, Nour Atmani, Viktor Stromtsov, Fatima Ali, Rim Tikarly, Sarah Ryad, Ghada Salah, Hayder Hasan, Reyad Obaid

“…With a rise in global incidence of overweight and obesity, the number of patients seeking weight management (WM) advice is likely to increase. …”
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Patient’s Information Toward Some Modifiable Risk Factors of Ischemic Heart Disease by Bayan Omar Sharif, Aras Hamad Rasul, Osman Ibrahim Mahmud, Farman Nuri Abdulla

“…However more than half of them had a high level of information about IHD as a general, and the TV was the first source of their information but more than half of them were overweight, 65% did not do regular exercise, 52.4% were relatively stressful. …”
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