Astragalin: A Bioactive Phytochemical with Potential Therapeutic Activities by Ammara Riaz, Azhar Rasul, Ghulam Hussain, Muhammad Kashif Zahoor, Farhat Jabeen, Zinayyera Subhani, Tahira Younis, Muhammad Ali, Iqra Sarfraz, Zeliha Selamoglu

“…This multifaceted compound is well known for its diversified pharmacological applications such as anti-inflammatory, antioxidant, neuroprotective, cardioprotective, antiobesity, antiosteoporotic, anticancer, antiulcer, and antidiabetic properties. It carries out the aforementioned activities by the regulation and modulation of various molecular targets such as transcription factors (NF-κB, TNF-α, and TGF-β1), enzymes (iNOS, COX-2, PGE2, MMP-1, MMP-3, MIP-1α, COX-2, PGE-2, HK2, AChe, SOD, DRP-1, DDH, PLCγ1, and GPX), kinases (JNK, MAPK, Akt, ERK, SAPK, IκBα, PI3K, and PKCβ2), cell adhesion proteins (E-cadherin, vimentin PAR-2, and NCam), apoptotic and antiapoptotic proteins (Beclin-1, Bcl-2, Bax, Bcl-xL, cytochrome c, LC3A/B, caspase-3, caspase-9, procaspase-3, procaspase-8, and IgE), and inflammatory cytokines (SOCS-3, SOCS-5, IL-1β, IL-4, IL-6, IL-8, IL-13, MCP-1, CXCL-1, CXCL-2, and IFN-γ). …”
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Five-year Variations in Air Pollutant Emissions with Ultra-low Emission Retrofits in a 660 MW Coal-fired Power Unit by Zhiyong Li, Zhuangzhuang Ren, Chengjing Cao, Chen Liu, Zhen Zhai, Jixiang Liu, Ziyi Zhan, Changtao Huang, Lan Chen, Hongdan Yuan

“…It was particularly pointed out that emissions increased again in 2017 though they still met the ULE standards, indicating the comprehensive consideration should be taken between the emission reductions and high cost of the ULE policy. …”
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Energetic and genomic potential for hydrogenotrophic, formatotrophic, and acetoclastic methanogenesis in surface-expressed serpentinized fluids of the Samail Ophiolite by Alta E. G. Howells, Alta E. G. Howells, Lilja M. Quinn, Lilja M. Quinn, Miguel G. Silva, Miguel G. Silva, Kylie Akiyama, Kylie Akiyama, Lucas M. Fifer, Lucas M. Fifer, Grayson Boyer, Srishti Kashyap, Kirt Robinson, Kirt Robinson, Jared Broddrick, Everett L. Shock, Tori M. Hoehler

“…We find that formatotrophic methanogenesis affords a higher Affinity (greater energetic yield) than acetoclastic and hydrogenotrophic methanogenesis in pristine serpentinized fluids and, in agreement with previous studies, find genomic evidence for a methanogen of the genus Methanobacterium to carry out formatotrophic and hydrogenotrophic methanogenesis, with the possibility of even using bicarbonate as a supply of CO2. …”
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HDL Particle Size and Functionality Comparison between Patients with and without Confirmed Acute Myocardial Infarction by Raissa de Miranda Teixeira, Nicole Cruz de Sá, Ana Paula Caires dos Santos, Vanessa Rocha Anjos e Silva, Elaine Christine de Magalhães Cabral Albuquerque, Luiz Claudio Lemos Correia, Ricardo David Couto

“…This study was carried out to evaluate the structure (molecular and particle size) and functionality of high-density lipoprotein (HDL) shortly after AMI, in the presence of acute inflammatory response. …”
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Screening for schistosomiasis in a non-endemic setting: Accuracy of a rapid antibody test using finger prick blood by Margherita Ortalli, Bianca Granozzi, Michele Bacchiega, Concettina Di Lillo, Greta Roncarati, Silvia Stefania Longoni, Cristina Mazzi, Elisa Vanino, Zeno Bisoffi, Stefania Varani

“…Serological screening is recommended but so far, no accurate point-of-care (POC) and lab-free test is available.We carried out a prospective evaluation of the accuracy of a new immunochromatographic test (Black- ICT, IgG-IgM) using finger prick blood for screening of schistosomiasis at the University Hospital of Bologna. …”
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Being a tree crop increases the odds of experiencing yield declines irrespective of pollinator dependence by Aizen, Marcelo A., Gleiser, Gabriela, Kitzberger, Thomas A., Milla, Ruben

“…Our analyses revealed a stronger association of yield decline with growth form than with pollinator dependence, a relationship that persisted after partialling out the effect of pollinator dependence. In particular, yield declines were more common among tree than herbaceous and shrub crops in all major regions but in Africa, a continent showing a high incidence of yield declines irrespective of growth form. …”
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The preference of migratory waterbirds to winter at a key location on the East Asian-Australasian flyway and its implications for habitat conservation by Shuangliang Dai, Yanyan Zhou, Jingsi Gao, Guowei Cheng, Linlin Wang, Haiyan Bai, Xiaoyu Lei, Hualin Xu, Xian-zhong Mao

“…Understanding the preference of migratory waterbirds to inhabit key habitats is crucial for mapping out effective management strategies to maintain migration network connectivity. …”
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Prehospital scale to differentiate intracerebral hemorrhage from large-vessel occlusion patients: a prospective cohort study by A. Freixa-Cruz, G. Jimenez-Jimenez, G. Mauri-Capdevila, Y. Gallego-Sánchez, A. García-Díaz, R. Mitjana-Penella, M. Paul-Arias, C. Pereira-Priego, E. Ruiz-Fernández, S. Salvany-Montserrat, A. Sancho-Saldaña, E. San-Pedro-Murillo, E. Saureu, D. Vázquez-Justes, Francisco Purroy

“…We compared clinical variables and vascular risk factors between ICH and LVO patients. Out of 989 stroke code patients, we included 190 (66.7%) LVO cases and 95 (33.3) ICH cases. …”
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Preparation and characterization of new silica-based heterofunctional biocatalysts utilizing low-cost lipase Eversa® Transform 2.0 and evaluation of their catalytic performance in... by Wagner C. A. Carvalho, Rayane A. S. Freitas, Milson S. Barbosa, Ariela V. Paula, Ernandes B. Pereira, Adriano A. Mendes, Elton Franceschi, Cleide M. F. Soares

“…Subsequently, the synthesis of esters of industrial interest was carried out through esterification using a lipase (Eversa Transform 2.0 (ET2.0)) immobilized by different functional groups on heterofunctional silica-based supports: epoxy-silica (Epx), glyoxyl-silica (Gly), and amino-glutaraldehyde-silica (AmG). …”
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Knowledge, Practices, and Attitudes Towards Silver Diamine Fluoride Therapy Among Dentists and Students in Southeastern Spain by Clara Serna-Muñoz, Marina Lucas-Porras, Yolanda Martínez-Beneyto, Amparo Pérez-Silva, Francisco Javier Ibañez-López, Antonio José Ortiz-Ruiz

“…<b>Methods:</b> A cross-sectional survey (questionnaire) was carried out aimed at final-year dental students (DSs) (n = 43) and registered dentists (GDPs) (n = 1050) in the autonomous community of the region of Murcia (Spain). …”
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Branched-chain amino acids levels associated with risk of erectile dysfunction: A Mendelian randomization analysis by Yijian Deng, Liying Zeng, Yigui Lai, Shuai Ji, Baizhao Peng, Hanqi Lu, Ming Wang, Hiu Yee Kwan, Qi Wang, Xiaoshan Zhao

“…A sensitivity analysis was performed employing leave-one-out analysis. Results: The MR analysis results indicate a positive correlation between levels of total BCAA (OR = 1.984, 95 % CI = 1.018–3.868, P = 0.044), leucine (OR = 2.277, 95 % CI = 1.121–4.626, P = 0.023), isoleucine (OR = 2.584, 95 % CI = 1.167–5.722, P = 0.019), valine (OR = 1.894, 95 % CI = 1.119–3.206, P = 0.017), and the risk of ED. …”
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Fetal Rhesus D Genotyping and Sex Determination from Maternal Plasma of Rhesus D-Negative Antenatal Population: The Usefulness of Conventional Polymerase Chain Reaction in Resource... by Otchere Addai-Mensah, Edward Y. Afriyie, Samuel Asamoah Sakyi, Christian Obirikorang, Max Efui Annani-Akollor, Eddie-Williams Owiredu, Francis A. Amponsah, Richard Vikpebah Duneeh, Evans Asamoah Adu

“…Blood samples were collected from each participant (in the third trimester of pregnancy) for DNA extraction/purification and fetal RhD genotyping. Results. Out of the 30 samples, 26 (86.7%) were found to be RhD+ while 4 (13.3%) were RhD−. …”
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Intraperitoneal paclitaxel for patients with primary malignant peritoneal mesothelioma: a phase I/II dose escalation and safety study—INTERACT MESO by Job P van Kooten, Jacobus W A Burger, Cornelis Verhoef, Joachim G J V Aerts, Eva V E Madsen, Alexandra R M Brandt-Kerkhof, Stijn L W Koolen, Ron H J Mathijssen, Michelle V Dietz, Niels A D Guchelaar

“…Through this PAC, 8–16 weekly cycles of intraperitoneal chemotherapy will be administered.Ethics and dissemination The Central Committee on Research Involving Human Subjects (CCMO, The Hague, The Netherlands) and the Medical Research Ethics Committee (METC, Rotterdam, The Netherlands) have granted permission to carry out this study protocol. The results of this trial will be submitted for publication in a peer-reviewed scientific journal.Trial registration number NL9718. …”
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Application of Wasted Oolong Tea as a Biosorbent for the Adsorption of Methylene Blue by Yunfei Hu, Yue Zhang, Yuqun Hu, Chen-Yao Chu, Jinke Lin, Shuilian Gao, Dongyi Lin, Jing Lu, Ping Xiang, Tzu-Hsing Ko

“…The effect of factors on adsorption efficiency, isotherms, kinetics, and potential mechanism was carried out. Adsorption capacity of MB onto wasted tea powder increased with the MB concentration and contact time, whereas the increase in pH value and ion strength appeared to have a negative effect for the adsorption process. …”
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Influence of Ultrasonic Activation on the Physicochemical Properties of Calcium Silicate-Based Cements by Fredson Márcio Acris De Carvalho, Yara Teresinha Corrêa Silva-Sousa, Carlos Eduardo Saraiva Miranda, Paulo Henrique Miller Calderon, Ana Flávia Simões Barbosa, Luciana Martins Domingues De Macedo, Fuad Jacob Abi Rached-Junior

“…The molds for analysis of the physicochemical properties were filled out and evaluated according to specification No. 57 from ANSI/ADA. …”
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Seabed Acoustic Mapping Revealing an Uncharted Habitat of Circular Depressions Along the Southeast Brazilian Outer Shelf by Ana Carolina Lavagnino, Marcos Daniel Leite, Tarcila Franco, Pedro Smith Menandro, Fernanda Vedoato Vieira, Geandré Carlos Boni, Alex Cardoso Bastos

“…The direct sampling was carried out by scuba-diving with video images and sediment samples collected inside and outside the depressions. …”
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Association between HLA-B Alleles and Carbamazepine-Induced Maculopapular Exanthema and Severe Cutaneous Reactions in Thai Patients by Chonlaphat Sukasem, Chonlawat Chaichan, Thapanat Nakkrut, Patompong Satapornpong, Kanoot Jaruthamsophon, Thawinee Jantararoungtong, Napatrupron Koomdee, Suthida Sririttha, Sadeep Medhasi, Sarawut Oo-Puthinan, Ticha Rerkpattanapipat, Jettanong Klaewsongkram, Pawinee Rerknimitr, Papapit Tuchinda, Leena Chularojanamontri, Napatra Tovanabutra, Apichaya Puangpetch, Wichai Aekplakorn

“…The aim of the present study was to carry out an analysis of the involvement of HLA-B alleles in carbamazepine-induced cutaneous adverse drug reactions (cADRs) in the Thai population. …”
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Equalizer Design: HBOA-DE-trained radial basis function neural networks by Santosh Kumar Das, Satya Ranjan Pattanaik, Pradyumna Kumar Mohapatra, Saroja Kumar Rout, Abdulaziz S. Almazyad, Muhammed Basheer Jasser, Guojiang Xiong, Ali Wagdy Mohamed

“…It has been shown that the projected method outclasses other methods even in poor signal-to-noise ratio conditions, which is borne out by extensive simulation studies.…”
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Obesity and polysomnographic variables on patients with obstructive sleep apnea by Chaiane Facco Piccin, Marco Colomé Beck, Luiz Carlos Alves de Oliveira, Reinaldo Fernando Cóser Neto, Pedro Luis Cóser, Fabrício Scapini, Antônio Marcos Vargas da Silva

“…Eighty eight patients were evaluated divided in eutrophic (EG; n=21; BMI=23.4±1.3kg/m2), overweight (OWG; n=34; BMI=27.5±1.4kg/m2) and obese group (OG; n=33; BMI=33.6±2.9kg/m2) that carried out all-night basal polysomnography for the diagnosis of Obstructive Sleep Apnea (OSA). …”
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A qualitative systematic review of umbilical cord care practices in Nigeria by Precious Ebube Anyakorah, Florence Chinelo Aguna, David Chinaecherem Innocent, Anthony Chinonso Uwandu-Uzoma, Uzochukwu Godswill Ekeleme, Chidera Chisom Obasi, Stanley Chinedu Eneh, Chidinma Peace Ahunam, Ihuoma Chimdimma Dike, Vivian Chidimma Maduekwe, Oluwaseunayo Deborah Ayando, Chinazaekpere Oguguo Duruji, Rejoicing Chijindum Innocent, Princess Chidiebube Uwaezuoke, Oluwafunmilayo Opeyemi Adenuga, Chiagoziem Ogazirilem Emerole

“…Results A total of 11 included studies were found out of 1532 studies. The findings reveal a range of cord care practices, emphasizing the use of various methods such as methylated spirit, hot compresses, and indigenous substances. …”
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