Antioxidant effect of Lactobacillus fermentum HFY02-fermented soy milk on D-galactose-induced aging mouse model by Tiantian Hu, Rui Chen, Yu Qian, Ke Ye, Xingyao Long, Kun-Young Park, Xin Zhao

“…Firstly, the optimal fermentation conditions was screened out by detecting the effects of different fermentation temperature and time on the active components and antioxidant activity of soybean milk in vitro. …”
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An Exceptionally Powerful, Radiatively Driven Ultrafast Outflow in the Rapidly Accreting AGN RE J1034+396 by Chloe S. Taylor, Daniel R. Wilkins, Steven W. Allen

“…The high terminal velocity and substantial absorbing column density imply that the outflow carries sufficient momentum and energy to transform its environment, being capable of driving out essentially all dust and gas it interacts with along the line of sight, even if the AGN were initially surrounded by a Compton-thick absorber.…”
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Modifiable risk factors for anemia among women of childbearing age in sub-saharan Africa (2015–2023) by Beminate Lemma Seifu, Yohannes Mekuria Negussie, Angwach Abrham Asnake, Bezawit Melak Fente, Zufan Alamrie Asmare, Mamaru Melkam, Meklit Melaku Bezie, Alemayehu Kasu Gebrehana, Sintayehu Simie Tsega, Hiwot Atlaye Asebe

“…Methods We conducted an analysis of the most recent Demographic and Health Surveys datasets from 21 Sub-Saharan Africa (SSA) countries, which were carried out between 2015 and 2023. Using multilevel multinomial regression models, we calculated the Adjusted Odds Ratio (AOR) with a 95% Confidence Interval, and subsequently estimated the Population Attributable Fraction (PAF) based on these AOR values. …”
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Transition Guide Dissemination to Foster Patient–Care Team Conversations: A Childhood Arthritis Rheumatology Research Alliance Transition Learning Collaborative Pilot Implementatio... by Joyce C. Chang, Gabrielle Alonzi, Cora Sears, Nicole Bitencourt, Alex Hernandez, Rosemary Peterson, Risa Alperin, Rebecca S. Overbury, Mariel dela Paz, Lindsay N. Waqar‐Cowles, Patience H. White, Kristine Carandang, Erica F. Lawson, for the CARRA Transition Workgroup

“…Results Six sites were retained through the COVID‐19 pandemic (below 70% target). Five out of six sites contributed outcome data (met 80% target) but with substantial heterogeneity in how transition guides were shared (eg, in‐person, electronic messages, and posted flyers), and data were collected. …”
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Hypofractionated partial breast irradiation after breast-conserving surgery for patients with early stage breast cancer in China Mainland: a single-arm prospective trial by Xiaomeng Zhang, Xiaofang Wang, Zhuohua Xu, Yajuan Chu, Xingxing Chen, Li Zhang, Jin Meng, Wei Shi, Zhaozhi Yang, Xin Mei, Xiaoli Yu, Zhen Zhang, Xiaomao Guo, Miao Mo, Guangyu Liu, Jiong Wu, Zhimin Shao, Jinli Ma

“…From Jan of 2015 to July of 2018, 208 out of 222 patients recruited were evaluable and included in final analysis. …”
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Association of Cardiovascular Autonomic Neuropathy and Distal Symmetric Polyneuropathy with All-Cause Mortality: A Retrospective Cohort Study by Orsolya E. Vági, Márk M. Svébis, Beatrix A. Domján, Anna E. Körei, Ildikó Istenes, Zsuzsanna Putz, Szilvia Mészáros, Noémi Hajdú, Magdolna Békeffy, Solomon Tesfaye, Péter Kempler, Viktor J. Horváth, Adam G. Tabák

“…However, the association between distal symmetric polyneuropathy (DSPN) or CAN with all-cause mortality is much less investigated. Thus, we set out to examine the effect of CAN and DSPN on all-cause mortality in a well-phenotyped cohort. …”
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The Equator Project Research School and Mentoring Network: Evaluated Interventions to Improve Equity in Geoscience Research by Natasha Dowey, Anya Lawrence, Munira Raji, Christopher Jackson, Rebecca Williams, Ben Fernando, Sam Giles, Jenni Barclay, Louisa Brotherson, Ethny Childs, Jacqueline Houghton, Anjana Khatwa, Keely Mills, George Jameson, Francisca Rockey, Steven Rogers, Catherine Souch

“…The Equator project set out to increase participation and retention of UK-domiciled Black, Asian and minority ethnic students in GEES research by developing evidence-based, ring-fenced, fully remunerated interventions. …”
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Bidirectional relationship between depression and activities of daily living and longitudinal mediation of cognitive function in patients with Parkinson’s disease by Yue Xu, Yue Xu, Durong Chen, Meiqi Dong, Yun Zhang, Yun Zhang, Hongmei Yu, Hongmei Yu, Hongmei Yu, Yanqing Han, Yanqing Han, Yanqing Han

“…Then, we explored the mediating role of cognitive function in the bidirectional relationship between depression and ADL in patients with PD, and the mediation effect test was carried out using a bias-corrected nonparametric percentile bootstrap approach.ResultsDepression in patients with PD predicted their subsequent ADL (β = 0.079, p < 0.01), and ADL also predicted their subsequent depression (β = 0.069, p < 0.05), In addition, Bootstrap analysis showed that cognitive function played a significant mediating role in prediction of depression to ADL in patients with PD (β = 0.006, p = 0.074, 95%CI = 0.001 ~ 0.014), and cognitive function also played a significant mediating role in prediction of depression to ADL (β = 0.006, p = 0.067, 95%CI = 0.001 ~ 0.013).ConclusionThere is a bidirectional relationship between depression and ADL in patients with PD. …”
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Multi-observatory Study of Young Stellar Energetic Flares (MORYSEF): No Evidence for Abnormally Strong Stellar Magnetic Fields after Powerful X-Ray Flares by Konstantin V. Getman, Oleg Kochukhov, Joe P. Ninan, Eric D. Feigelson, Vladimir S. Airapetian, Abygail R. Waggoner, L. Ilsedore Cleeves, Jan Forbrich, Sergio A. Dzib, Charles J. Law, Christian Rab, Daniel M. Krolikowski

“…Our findings reveal magnetic field strengths at the stellar surface typical of nonflaring PMS stars, ruling out the need for abnormally strong fields during flares. …”
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improving Pain mAnagement for childreN and young people attendeD by Ambulance (PANDA): protocol for a realist review. [version 3; peer review: 2 approved, 1 approved with reservati... by Paul Leighton, Georgette Eaton, Georgie Nicholls, Kacper Sumera, Marishona Ortega, Jessica Hodgson, Michael Baliousis, Aloysius Niroshan Siriwardena, Despina Laparidou, Bill Lord, Sarah Redsell, Gregory Adam Whitley, Tatiana Bujor

“…Studies have shown that prehospital pain management in CYP is poor, with 61% of those suffering acute pain not achieving effective pain relief (abolition or reduction of pain score by 2 or more out of 10) when attended by ambulance. Consequences of poor acute pain management include altered pain perception, post-traumatic stress disorder and the development of chronic pain. …”
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A Simple Machine Learning-Based Quantitative Structure–Activity Relationship Model for Predicting pIC₅₀ Inhibition Values of FLT3 Tyrosine Kinase by Jackson J. Alcázar, Ignacio Sánchez, Cristian Merino, Bruno Monasterio, Gaspar Sajuria, Diego Miranda, Felipe Díaz, Paola R. Campodónico

“…Rigorous internal validation via leave-one-out and 10-fold cross-validation yielded <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msup><mi mathvariant="normal">Q</mi><mn>2</mn></msup></semantics></math></inline-formula> values of 0.926 and 0.922, respectively, while external validation on 270 independent compounds resulted in an R² value of 0.941 with a standard deviation of 0.237. …”
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Clinical Recommendations of Russian Gastroenterological Association and RENDO Endoscopic Society on Diagnosis and Treatment of Gastritis and Duodenitis by V. T. Ivashkin, I. V. Maev, T. L. Lapina, E. D. Fedorov, A. A. Sheptulin, A. S. Trukhmanov, A. V. Kononov, R. A. Abdulkhakov, O. P. Alexeeva, S. A. Alekseenko, D. N. Andreev, E. K. Baranskaya, N. N. Dekhnich, I. L. Klyaritskaya, R. S. Kozlov, E. A. Kogan, M. P. Korolev, N. V. Korochanskaya, S. A. Kurilovich, M. A. Livsan, M. F. Osipenko, P. V. Pavlov, S. S. Pirogov, A. S. Sarsenbaeva, V. I. Simanenkov, A. S. Tertychny, A. V. Tkachev, Yu. P. Uspensky, I. B. Khlynov, V. V. Tsukanov

“…With focal restricted intestinal metaplasia, follow-up is not required in most cases, mainly when advanced atrophic gastritis is ruled out in high-quality endoscopy with biopsy. However, a familial history of gastric cancer, incomplete intestinal metaplasia and persistent H. pylori infection render endoscopy monitoring with chromoendoscopy and targeted biopsy desirable once in three years. …”
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A Study on the Safety and Efficacy of an Innovative Hydrophilic Dialysis Membrane by Francisco Maduell, Victor Joaquín Escudero-Saiz, Elena Cuadrado-Payán, Maria Rodriguez-Garcia, Miquel Gómez, Lida María Rodas, Néstor Fontseré, Maria del Carmen Salgado, Gregori Casals, Nayra Rico, José Jesús Broseta

“…A prospective study was carried out in 20 patients. Patients underwent five dialysis sessions with the same routine dialysis parameters: four sessions with the Toraylight NV 2.1 (HD, post-dilution HDF with 50, 75 or auto-substitution Qi) and one with the FX CorAL 800 (post-dilution HDF with auto-substitution Qi). …”
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Evaluation of exo-long noncoding RNA MALAT1 in OSCC in comparison to dysplastic and normal: A cross-sectional study by Ramya Sekar, Selvaraj Jayaraman, VishnuPriya Veeraraghavan, Kalaiselvi Krishnamoorthy, Shubhra Chauhan Aramanai, Sathan Raj Natarajan

“…Conclusion: MALAT1 stands out as a key player in the complex landscape of OSCC pathogenesis, impacting tumorigenesis, metastasis, and treatment outcomes through multifaceted molecular mechanisms. …”
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Evaluation of the Diversities in the Inflammatory Responses in Cats With Bacterial and Viral Infections by Songul Erhan, Bengu Bilgic, Ezgi Ergen, Mert Erek, Elif Ergul Ekiz, Mukaddes Ozcan, Mehmet Erman Or, Banu Dokuzeylul, Erdal Matur

“…This study aimed to investigate the diversities of inflammatory responses between bacterial and viral infections in cats to figure out their role in the pathophysiology of these infections. …”
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Analysis of influencing factors of washed microbiota transplantation in treating patients with metabolic syndrome by De-Jiang Lin, Dong-Xia Hu, Qing-Ting Wu, Lin-Gui Huang, Zi-Han Lin, Jia-Ting Xu, Xing-Xiang He, Lei Wu, Lei Wu

“…Not only the changes in body mass index [BMI = weight (kg)/height (m)2], blood glucose, blood lipids, and blood pressure were analyzed, but also the influencing factors of WMT in treating MS patients were carried out based on Logistic Regression. The 16S rRNA gene amplicon sequencing was performed on fecal samples before and after WMT treatment.ResultsA total of 210 patients were included, including 68 patients in the WMT group and 142 patients in the drug treatment (DT) group. …”
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Apoptosis in the liver of male <em>db/db</em> mice during the development of obesity and type 2 diabetes by S. V. Michurina, I. Yu. Ishchenko, S. A. Arkhipov, M. A. Cherepanova, D. V. Vasendin, E. L. Zavjalov

“…Immunohistochemical analysis (using the indirect avidin-biotin peroxidase method) and morphometric evaluation of the expression of the antiapoptotic protein Bcl-2 and the proapoptotic protein Bad in liver cells of studied animals at different stages of obesity and DM2 were carried out. An excess of the value of the Bcl-2 protein staining area over the Bad protein staining area was revealed in the liver of 10-week-old animals. …”
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Evaluation of variation in special educational needs provision and its impact on health and education using administrative records for England: umbrella protocol for a mixed-method... by Stuart Logan, Ruth Gilbert, Tamsin Ford, Johnny Downs, Jugnoo Rahi, Ania Zylbersztejn, Katie Harron, Kate Boddy, Bianca De Stavola, Vincent Nguyen, Isaac Winterburn, Kate Lewis, Lucy Karwatowska, Lorraine Dearden, Sarah Barnes, Jacob Matthews, Matthew Lilliman, Jennifer Saxton, Antony Stone, Kristine Black-Hawkins

“…This umbrella protocol sets out analyses across four work packages (WP). WP1 defined a range of ‘health phenotypes’, that is health conditions expected to need SEN provision in primary school. …”
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The multi-omics signatures of telomere length in childhood by Congrong Wang, Dries S. Martens, Mariona Bustamante, Rossella Alfano, Michelle Plusquin, Lea Maitre, John Wright, Rosemary R. C. McEachan, Johanna Lepeule, Remy Slama, Marina Vafeiadi, Leda Chatzi, Regina Grazuleviciene, Kristine B. Gutzkow, Hector Keun, Eva Borràs, Eduard Sabidó, Angel Carracedo, Georgia Escarami, Augusto Anguita-Ruiz, Dolors Pelegrí-Sisó, Juan R. Gonzalez, Martine Vrijheid, Tim S. Nawrot

“…Results After multiple-testing correction, only two CpGs (cg23686403 and cg16238918 at PARD6G gene) out of all the omics features were significantly associated with child telomere length. …”
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Clinical Outcomes and Patterns of Traumatic Injuries Associated with Subway Incidents at a Level 1 Trauma Center by Bharti Sharma, Aubrey May B. Agcon, George Agriantonis, Sittha Cheerasarn, Navin D. Bhatia, Zahra Shafaee, Jennifer Whittington, Kate Twelker

“…Patients were identified using International Classification of Diseases (ICD) injury descriptions and Abbreviated Injury Scale (AIS) body regions. Results: Out of 360 patients (total), 23.5% presented with head injuries with an AIS score ≥ 3. …”
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