Optical genome mapping: Unraveling complex variations and enabling precise diagnosis in dystrophinopathy by Jiahui Mai, Jing Duan, Xiaoyu Chen, Liqin Liu, Dachao Liang, Tao Fu, Gang Lu, Wai Yee Chan, Xufeng Luo, Feiqiu Wen, Jianxiang Liao, Zhuo Li, Xinguo Lu

“…Results Conventional methods (MLPA and NGS) failed to detect pathogenic mutations in six out of eight individuals (four males and two females). …”
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Multiple low-dose radiation ameliorates type-2 diabetes mellitus via gut microbiota modulation to activate TLR4/MyD88/NF-κB pathway by Lijing Qin, Rongrong Liu, Zhen Jia, Weiqiang Xu, Li Wang, Hongyuan Tian, Xinru Lian, Wen Li, Yali Qi, Huan He, Zhicheng Wang

“…Metabolic profiling was carried out using the liquid mass spectrometry system, followed by the combinative analysis of gut microbiota alteration. …”
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Predicting Time in Range Without Hypoglycaemia Using a Risk Calculator for Intermittently Scanned CGM in Type 1 Diabetes by Fernando Sebastian‐Valles, Jose Alfonso Arranz Martin, Julia Martínez‐Alfonso, Jessica Jiménez‐Díaz, Iñigo Hernando Alday, Victor Navas‐Moreno, Teresa Armenta Joya, Maria del Mar delFandiño García, Gisela Liz Román Gómez, Jon Garai Hierro, Luis Eduardo Lander Lobariñas, Carmen González‐Ávila, Purificación deMartinez de Icaya, Vicente Martínez‐Vizcaíno, Miguel Antonio Sampedro‐Nuñez, Mónica Marazuela

“…Model reliability was assessed via external validation in the second sample and internal validation using bootstrap resampling. Results Out of 2314 models explored, the most effective predictor model included annual net income per person, sex, age, diabetes duration, pre‐isCGM HbA1c, insulin dose/kg, and the interaction between sex and HbA1c. …”
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High-dose glucocorticoid treatment vs. glucocorticoid replacement in immune checkpoint inhibitor associated hypophysitis (CORTICI): an open, randomised controlled trial by Verena Theiler-Schwetz, Christian Trummer, Lisa Schmitt, Angelika Terbuch, Barbara Obermayer-Pietsch, Erika Richtig, Stefan Pilz

“…The primary outcome was the frequency of hormonal axes recovery.Results Between 17th April 2019 and 16th September 2022, 18 out of the 20 randomised patients finished the trial; eight completed high-dose, 10 glucocorticoid replacement. …”
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The significant role of IL-15, IL-22, IL-37, and caspase 9 in polycystic ovary syndrome: A case-control study in a sample of Iraqi women by Noor A. Mohammed, Ghassan M. Sulaiman, Hazima M. Alabassi, Khalil A.A. Khalil, Elsadig M. Ahmed

“…The ELISA technique has been carried out to determine the serum levels of understudied factors mentioned above in Iraqi women patients diagnosed with PCOS (No. = 90) via a specialized gynecologist and healthy fertile women (No. = 48) as a control group. …”
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Long-term results of antiviral therapy in patients with chronic hepatitis C with sustained virologic response by T. M. Ignatova, T. N. Lopatkina, V. P. Chulanov, Ye. V. Gaydasheva, S. N. Batskikh, G. V. Mikhaylovskaya, D. T. Abdurakhmanov, S. Yu. Karpov, Ye. N. Nikulkina, O. A. Chernova

“…Standard clinical and laboratory investigation and evaluation of RNA HCV was carried out. In 114 patients RNA HCV and DNA HBV in blood serum and peripheral mononuclear blood cells were studied by polymerase chain reaction (PCR) with fluorescent hybridization detection in «real time» mode (sensitivity of 10 IU/ml for HCV and 5 IU/ml for HBV).Results. …”
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Seasonal Variation in the Intake of Food Groups and Nutrients in Japan: A Systematic Review and Meta-analysis by Riho Adachi, Fumi Oono, Mai Matsumoto, Xiaoyi Yuan, Kentaro Murakami, Satoshi Sasaki, Hidemi Takimoto

“…Significant seasonal differences were observed for vegetables, fruits, and potatoes in five out of six comparisons, though the heterogeneity was high. …”
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Serum matrix metalloproteinase‐7, Syndecan‐1, and CA 19‐9 as a biomarker panel for diagnosis of pancreatic ductal adenocarcinoma by Doron Yablecovitch, Moshe Nadler, Shomron Ben‐Horin, Orit Picard, Miri Yavzori, Ella Fudim, Moran Tardio Duchan, Emad Sakhnini, Alon Lang, Maor Lahav, Talia Saker, Sandra Neuman, Limor Selinger, Biana Freitz, Revital Dvir, Maria Raitses‐Gurevich, Talia Golan, Idan Levy, Ido Laish

“…Conclusions Due to its high sensitivity, this biomarker panel has the potential to rule out PDAC in suspected cases.…”
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Research Review and Prospect of Litchi Fruit Cracking by Xiwen LI, Haoshuang SUN, Xuequn PANG, Zhaoqi ZHANG

“…., and the research progress in its physiology and molecular biology including pulp TSS, calcium content, cell wall components and their associated enzymes. The review points out that although there are great differences in the susceptibility of fruit cracking among different litchi varieties, so far, we have not been able to identify the key enzymes or major genes related to fruit cracking; compared with other fruits, litchi fruit cracking has a certain degree of specificity, which is manifested in that litchi fruit cracking peaks at the stage from the green fruit stage to the color turning stage, and that the fruits always crack along the suture line with the pulp remaining intact. …”
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Investigation on Mechanical Properties and Reaction Characteristics of Al-PTFE Composites with Different Al Particle Size by Jia-xiang Wu, Xiang Fang, Zhen-ru Gao, Huai-xi Wang, Jun-yi Huang, Shuang-zhang Wu, Yu-chun Li

“…As the Al particle size rose, the ignition energy of the composites enhanced and the composites turned out to be more insensitive to reaction. In a lower strain rate range (10−2·s−1∼102·s−1), Al-PTFE specimens take on different mechanical properties and reaction characteristics in the case of different strain rates. …”
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Numerical Simulation Study on Fish Habitats in the Downstream Section of Yangqu Hydropower Station by Qiaoling Zhang, Youjie Ou, Weiying Wang, Guoyong Zhang, Zijun Liu, Shanshan Li, Guodong Li

“…ABSTRACT To promote the coordinated and sustainable development of hydropower exploitation and ecological environment in the upper reaches of the Yellow River, a fine simulation of the downstream riverway of Yangqu Hydropower Station was carried out to analyze the impact of the changes in water depth and flow velocity on fish habitats after the impoundment of Yangqu Hydropower Station. …”
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Burden of hospitalizations in newly diagnosed heart failure patients in Poland: real world population based study in years 2013–2019 by Przemysław Leszek, Daniel Waś, Kinga Bartolik, Kladiusz Witczak, Andrzej Kleinork, Bohdan Maruszewski, Katarzyna Brukało, Paulina Rolska‐Wójcik, Małgorzata Celińska‐Spodar, Tomasz Hryniewiecki, Marta Załęska‐Kocięcka

“…Between 1 January 2013 and 31 December 2019, there were 1 124 118 newly diagnosed heart failure patients in Poland in both out‐ and inpatient settings. The median observation time was 946 days. …”
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Differential Signature of the Centrosomal MARK4 Isoforms in Glioma by Ivana Magnani, Chiara Novielli, Laura Fontana, Silvia Tabano, Davide Rovina, Ramona F. Moroni, Dario Bauer, Stefania Mazzoleni, Elisa A. Colombo, Gabriella Tedeschi, Laura Monti, Giovanni Porta, Silvano Bosari, Carolina Frassoni, Rossella Galli, Lorenzo Bello, Lidia Larizza

“…Results: Mutation analysis rules out sequence variations as the cause of the altered MARK4 expression in glioma. …”
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Quantitative Characterization for the Micronanopore Structures of Terrestrial Shales with Different Lithofacies Types: A Case Study of the Jurassic Lianggaoshan Formation in the So... by Weiwei Liu, Kun Zhang, Qianwen Li, Zhanhai Yu, Sihong Cheng, Jiayi Liu, Pei Liu, Fengli Han, Liangyi Tang, Zhengwei Li, Xuejiao Yuan, Yiming Yang, Yao Zeng, Chen Zhang

“…Besides, experiments including oil washing, the adsorption/desorption of CO2 and nitrogen, and high-pressure mercury pressure experiments were carried out. The pore structure of different petrographic types of terrestrial shales can be accurately and quantitatively characterized with these works. …”
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Development of a neural network for diagnosing the risk of depression according to the experimental data of the stop signal paradigm by M. O. Zelenskih, A. E. Saprygin, S. S. Tamozhnikov, P. D. Rudych, D. A. Lebedkin, A.  N. Savostyanov

“…A comparison of neural network technologies and methods of mathematical statistics was carried out. A neural network was implemented to diagnose the risk of depression using stop-signal paradigm data. …”
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Depth variations as effective indicators for strength variation of Najran granites, Najran region, Saudi Arabia by Ahmed Abd El Aal, Yahya Al Zamana, Turki Dunquwah, Omar Alsalmi, Jabir Hussain, Javed Iqbal, Moustafa Abdulrahim Mohamedsalih, Ahmed E. Radwan, Hezam Al-Awah

“…For a better knowledge of the granites throughout the region, it is advised to carry out comparative studies on other granites in Saudi Arabia and create a comprehension model using numerical simulation.…”
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Preparation and Characterisation of Polypyrrole-Iron Oxyhydroxide Nanocomposite as Sensing Material by Farah Nabila Diauudin, Siti Aminah Mohd Noor, Jahwarhar Izuan Abdul Rashid, Victor Feizal Knight, Wan Md Zin Wan Yunus, Keat Khim Ong, Noor Azilah Mohd Kasim, Safura Taufik, Alinda Samsuri, Intan Juliana Shamsudin, Wahhida Latip

“…Polypyrrole (PPy) has been widely used as a sensing material in many studies as PPy gives out noticeable reactions towards varieties of vapours of acids, bases, alcohols, alkanes, and chemical warfare agent (CWA) simulants. …”
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Development of Attenuated Total Reflectance Mid-Infrared (ATR-MIR) and Near-Infrared (NIR) Spectroscopy for the Determination of Resistant Starch Content in Wheat Grains by Rong Wang, Xia Wei, Hongpan Wang, Linshu Zhao, Cengli Zeng, Bingrui Wang, Wenying Zhang, Luxiang Liu, Yanhao Xu

“…Two high grain RS content wheat mutants were screened out by the ATR-MIR best calibration model from the wheat mutant library. …”
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Virulence and Antimicrobial Resistance Patterns of Salmonella spp. Recovered From Migratory and Captive Wild Birds by Ruhena Begum, Nilima Akther Asha, Diponkar Chandra Chanda Dipu, Milton Roy, Asikur Rahman, Md. Shahidur Rahman Chowdhury, Hemayet Hossain, Md. Rafiqul Islam, Md Bashir Uddin, Md. Mahfujur Rahman, Md. Mukter Hossain

“…Method A total 262 faecal samples were collected, and the identification of Salmonella spp. was carried out using a standard culture and PCR as well as molecular detection of virulence and AMR genes. …”
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Mind the blind spot: lessons from fungal community sequencing in a plant–soil feedback experiment by Mengshuai Liu, Jose G. Maciá-Vicente, Jasper van Ruijven, Wopke van der Werf, Zhenling Cui, Fusuo Zhang, Chunxu Song, Liesje Mommer

“…However, we cannot rule out that our results were affected by the high abundance of one particular cellulose-degrading fungus. …”
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