Effect of Mesenchymal Stem Cells and Platelet-Rich Plasma on the Bone Healing of Ovariectomized Rats by Bo Wei, Chengshuo Huang, Mingyan Zhao, Peng Li, Xiang Gao, Junchao Kong, Yanru Niu, Rui Huang, Juanhua Quan, Jinsong Wei, Jiaqi Chu

“…These results indicate that PRP treatment enhances bone microarchitecture in osteoporosis. Moreover, expression levels of osteogenesis-specific marker genes including RUNX2, OSX, and OPN were significantly upregulated in rats treated with PRP and BMSCs compared to those of other groups. …”
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Patterns of Comorbidity and Multimorbidity Among Patients With Multiple Sclerosis in a Large US Commercially Insured and Medicare Advantage Population by Dingwei Dai, Ajay Sharma, Amy L. Phillips, Carroline Lobo

“…Age-related and other comorbidities (ie, hypertension, hyperlipidemia, dyspepsia, osteoarthritis, osteoporosis, glaucoma, diabetes, cerebrovascular, cancer) were more common among patients 65 years and older Medicare Advantage (all _P_ < .0001). …”
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Correlation Between Objective Habit Metrics and Objective Medication Adherence: Retrospective Study of 15,818 Participants From Clinical Studies by Antoine Pironet, L Alison Phillips, Bernard Vrijens

“…These participants took part in 108 clinical studies mainly focused on treatments for hypertension (n=4737, 30%) and osteoporosis (n=3353, 21%). The SD of the hour of intake was significantly negatively correlated with the 2 objective adherence metrics: proportion of correct days (Spearman correlation coefficient, ρS=–0.62, P<.001) and proportion of doses taken (ρS=–0.09, P<.001). …”
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The Bony Density of the Pedicle Plays a More Significant Role in the Screw Anchorage Ability Than Other Regions of the Screw Trajectory by Zan Chen, Yue Chen, Jiajun Zhou, Yanwei He, Jingchi Li

“…ABSTRACT Objective Osteoporosis is a crucial risk factor for screw loosening. …”
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Clinical Characteristics of Aldosterone- and Cortisol-Coproducing Adrenal Adenoma in Primary Aldosteronism by Lu Tang, Xintao Li, Baojun Wang, Xin Ma, Hongzhao Li, Yu Gao, Liangyou Gu, Wenyuan Nie, Xu Zhang

“…Moreover, they had higher proportions of cardiovascular complications, glucose intolerance/diabetes, and osteopenia/osteoporosis compared to the pure APA patients (P<0.001). …”
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Comparison of fracture risk calculators in elderly fallers: a hospital-based cross-sectional study by Sophia von Widekind, Georgi Todorov, Susan Brook, Nicole Quah Qin Xian, Bernard Freudenthal, Alexander N Comninos

“…Objective Elderly patients presenting with falls are known to carry an extremely high risk of future fragility fractures. Current osteoporosis guidelines recommend using fracture risk calculators such as FRAX, QFracture or Garvan to guide management. …”
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Bone Mineral Density, TBS, and Body Composition Indexes in Ukrainian Men with Parkinson’s Disease by Vladyslav Povoroznyuk, Maryna Bystrytska, Nataliia Grygorieva, Iryna Karaban, Nina Karasevich

“…Our study showed an increased incidence of osteoporosis and significantly lower total body BMD (respectively, 1.20 ± 0.13 and 1.26 ± 0.10 g/cm2, p=0.05), but not lumbar spine and femoral neck BMDs, and higher TBS value in PD men comparing to the control group (respectively, 1.33 ± 0.12 and 1.22 ± 0.18 un., p=0.005). …”
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Association between fibrinogen-to-albumin ratio and bone metabolism markers (β-CTX and P1NP) in Chinese individuals with osteoporotic fracture: a cross-sectional investigation by Li-long Feng, Ke Lu, Chong Li, Min-zhe Xu, Yao-wei Ye, Yi Yin, Hui-qiang Shan

“…The study may provide a novel clinical implication by introducing FAR as a potential reference indicator for assessing bone health, offering a cost-effective and conveniently obtainable biomarker to monitor inflammation to improve bone metabolism in the treatment of osteoporosis.…”
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The relationship between non-HDL-C/HDL-C ratio and bone mineral density: an NHANES study by Shuo Qi, Biao Peng, Zhanwang Xu, Daodi Qiu, Guoqing Tan

“…These findings offer a new perspective on the relationship between lipid metabolism and bone metabolism and provide scientific evidence for the development of personalized osteoporosis prevention and treatment strategies.…”
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GnIH secreted by green light exposure, regulates bone mass through the activation of Gpr147 by Yu You, Konglin Huo, Liang He, Tongyue Wang, Lei Zhao, Rong Li, Xiaoqing Cheng, Xuebin Ma, Zhiying Yue, Stefan Siwko, Ning Wang, Lujian Liao, Mingyao Liu, Jian Luo

“…Therefore, our study elucidates that GnIH plays an important role in maintaining bone homeostasis via modulating osteoclast differentiation and demonstrates the potential of GnIH therapy or green light therapy in preventing osteoporosis.…”
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The simpler modified fried frailty scale predicts 2-year mortality in older adults with heart failure: a pilot study by Celalettin Küçük, Serdar Özkök, Gülistan Bahat, Ekrem Bilal Karaayvaz, Mustafa Altınkaynak, Alpay Medetalibeyoğlu, Mehmet Akif Karan

“…FRAIL scale, the Study of Osteoporosis Fractures (SOF) index, and Edmonton Frailty Scale (EFS) were alternatively used to study the correlation of SMFFS with different scales. …”
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The Influence of Ficus deltoidea in Preserving Alveolar Bone in Ovariectomized Rats by N. I. Omar, B. Baharin, S. F. Lau, N. Ibrahim, N. Mohd, A. Ahmad Fauzi, N. Muhammad, N. M. Fernandez

“…In conclusion, F. deltoidea has the capacity to prevent alveolar bone loss in ovariectomy-induced osteoporosis rats by potentially preserving trabecular bone microarchitecture and to decrease osteoclast and increase osteoblast cell count.…”
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Clinical code usage in UK general practice: a cohort study exploring 18 conditions over 14 years by Christos Grigoroglou, Darren M Ashcroft, Evangelos Kontopantelis, David Reeves, Salwa S Zghebi, Rosa Parisi, Brian McMillan

“…Objective To assess the diagnostic Read code usage for 18 conditions by examining their frequency and diversity in UK primary care between 2000 and 2013.Design Population-based cohort studySetting 684 UK general practices contributing data to the Clinical Practice Research Datalink (CPRD) GOLD.Participants Patients with clinical codes for at least one of asthma, chronic obstructive pulmonary disease, diabetes, hypertension (HT), coronary heart disease, atrial fibrillation (AF), heart failure, stroke, hypothyroidism, chronic kidney disease, learning disability (LD), depression, dementia, epilepsy, severe mental illness (SMI), osteoarthritis, osteoporosis and cancer.Primary and secondary outcome measures For the frequency ranking of clinical codes, canonical correlation analysis was applied to correlations of clinical code usage of 1, 3 and 5 years. …”
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Tissue Distribution of Total Flavonoids Extracts of Drynariae Rhizoma in Young and Old Rats by UPLC–MS/MS Determination by Yue Zhang, Xia Lei, Hongdan Xu, Guoliang Liu, Yeqiu Wang, Huifeng Sun, Fang Geng, Ning Zhang

“…Sm. has been extensively used in China, Japan, and Korea to treat osteoporosis and tonify kidneys. A rapid and validated UPLC-MS/MS method for simultaneous determination of the seven analytes including neoeriocitrin, luteolin-7-O-β-D-glucoside, astragalin, naringin, eriodictyol, naringenin, and kaempferol in rats’ various tissues (heart, liver, spleen, lung, kidney, stomach, brain, uterus, ovary, and small intestine) using quercetin as the internal standard (IS) was developed after oral administration of TFDR to rats. …”
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A Pilot Genome-Wide Association Study in Postmenopausal Mexican-Mestizo Women Implicates the RMND1/CCDC170 Locus Is Associated with Bone Mineral Density by Marisela Villalobos-Comparán, Rogelio F. Jiménez-Ortega, Karol Estrada, Alma Y. Parra-Torres, Anahí González-Mercado, Nelly Patiño, Manuel Castillejos-López, Manuel Quiterio, Juan Carlos Fernandez-López, Bertha Ibarra, Sandra Romero-Hidalgo, Jorge Salmerón, Rafael Velázquez-Cruz

“…We also compared our results with those of the Genetic Factors for Osteoporosis (GEFOS) Consortium meta-analysis. The comparison revealed two loci previously reported in the GEFOS meta-analysis: SOX6 (rs7128738) and PKDCC (rs11887431) associated with FN and LS BMD, respectively, in our study population. …”
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Nutritional and General Awareness of Vitamin D Status among Adult Population in Sulaymaniyah Governorate, Kurdistan Region, Iraq: A Cross-Sectional Study by Reder Rafiq Mohammed Salih, Fadhluddin Nasruddin Shakor, Dalia Ardal Ali, Rafiq Mohammed Salih Rashid

“…Nevertheless, more than two-thirds (83.3%) of participants defined the positive role of vitamin D in preventing osteoporosis and immune system strengthening (61%). Furthermore, nutritional awareness among the participants was variable. …”
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Evaluating pre-processing and deep learning methods in medical imaging: Combined effectiveness across multiple modalities by Thien B. Nguyen-Tat, Tran Quang Hung, Pham Tien Nam, Vuong M. Ngo

“…These datasets include two X-ray collections: the COVID-19 Pneumonia Normal Chest PA Dataset and the Osteoporosis Knee X-ray Dataset; two CT scan datasets: the Chest CT-Scan Images Dataset and the Brain Stroke CT Image Dataset; two MRI datasets: the Breast Cancer Patients MRI and the Brain Tumor MRI Dataset; and two ultrasound datasets: the Ultrasound Breast Images for Breast Cancer and the MT Small Dataset. …”
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Prediction of subsequent vertebral fracture after percutaneous vertebral augmentation using MRI-based vertebral bone quality and CT-based Hounsfield units: a retrospective cross-se... by Youdi Xue, Kun Shi, Weixiang Dai, Chao Ma, Jie Li

“…Computed tomography (CT)-based Hounsfeld units (HU) and magnetic resonance imaging (MRI)-based vertebral bone quality (VBQ) score can evaluate osteoporosis quantitatively, hyperlipidemia(HLP) might affect measurement result of VBQ score. …”
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Adult hypophosphatasia presenting with recurrent acute joint pain by Hayao Yoshida, Takaaki Murakami, Atsubumi Ogawa, Takashi Sunouchi, Naoko Hidaka, Nobuaki Ito, Hiromi Murakami, Hidenori Kawasaki, Tomoyuki Akiyama, Katsumi Nakajima, Daisuke Yabe, Taizo Yamamoto

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Oblique Lumbar Interbody Fusion Combined With Anterolateral Fixation and Cement Augmentation for the Treatment of Degenerative Lumbar Diseases in the Elderly Population: A Retrospe... by Weiqi Han, Lei He, Fei Wang, Xiaofeng Zhao, Cong Jin

“…ABSTRACT Objectives Cage subsidence is a common complication of oblique lumbar interbody fusion (OLIF), particularly in elderly patients with osteoporosis or osteopenia. While bilateral pedicle screw fixation (BPS) is effective in reducing subsidence, it is associated with longer operative times, increased blood loss, and greater tissue trauma. …”
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