A two-sample bidirectional Mendelian randomization analysis between telomere length and hyperthyroidism by Shiben Zhu, Ziyu Hao, Qihang Chen, Xiaoliu Liu, Wenyan Wu, Fang Zhang

“…Backgroundhyperthyroidism characterized by low thyrotropin, highlighting complications and risks, including cardiac issues, osteoporosis, adverse pregnancy outcomes, unintentional weight loss, and increased mortality associated with untreated hyperthyroidism. …”
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Protein Kinase A Is Involved in Neuropathic Pain by Activating the p38MAPK Pathway to Mediate Spinal Cord Cell Apoptosis by Yajun Deng, Liang Yang, Qiqi Xie, Fengbiao Yang, Guoqiang Li, Guangzhi Zhang, Shaoping Li, Zuolong Wu, Jing Wang, Xuewen Kang

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Prevention and treatment of recurrent fractures after percutaneous vertebroplasty with denosumab in patients with osteoporotic vertebral compression fractures by Shouyu Xiang, Cheng Tang, Long Ling, Wei Liu, Bingwen Bai, Yanming Cao

“…[Methods] A total of 72 patients diagnosed with osteoporotic vertebral compression fracture and treated by percutaneous vertebroplasty in the orthopedic department of the Second Affiliated Hospital of Guangzhou Medical University from January 2022 to December 2022 were selected as the study subjects.Patients were randomly divided into two groups, each had 36 cases.The control group received conventional anti-osteoporosis treatment, and the observation group added denosumab on the basis of control group treatment.Both groups were followed for 1 year, while the fracture rate and the levels of bone mineral density(BMD), visual analogue scale(VAS) score, oswestry disability index(ODI), beck value, sagittal cobb angle and procollagen type ⅠN-terminal propeptid(PINP) and β-carboxy-terminal cross-linked telopeptide of type Ⅰ collagen(β-CTX) were compared between the two groups. …”
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Exosomal non-coding RNAs in the regulation of bone metabolism homeostasis: Molecular mechanism and therapeutic potential by Chengxiong Huang, Yu Xiao, Liming Qing, Juyu Tang, Panfeng Wu

“…Bone metabolic disorders can lead to metabolic bone disease. Osteoporosis (OP), osteoarthritis (OA) and femoral head necrosis (ONFH) are common metabolic bone diseases. …”
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A systematic review of Aspilia africana (Pers.) C.D. adams traditional medicinal uses, phytoconstituents, bioactivities, and toxicities by Roggers Gang, Denis Okello, Yeongjun Ban, Youngmin Kang

“…Adams, popularly referred to as wild sunflower, has been used for generations across several African communities to treat various diseases, including malaria, wounds, osteoporosis, diabetes mellitus, gastric ulcers, measles, tuberculosis, stomach ache, rheumatic pains, and gonorrhea. …”
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Treatment of a femoral neck fracture in a patient with dwarfism: a case report by Junyan Zhao, Liuliu Chen, Kun He, Muyao Li, Zhenwen Li, Hui Lin, Songjun Li

“…The patient presented with characteristic features of dwarfism, including diminutive stature (1.2 m), multiple skeletal abnormalities, and significant osteoporosis. X-ray and hierarchical phase-contrast tomography examinations of the left hip joint revealed a displaced subcapital femoral neck fracture with compromised bone quality and a notably narrow medullary cavity. …”
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Risk factors of stroke-related sarcopenia: a systematic review and meta-analysis by Huan Yan, Juan Li, Lihong Xian, Yujie Li, Simin Li, Qinghua Wen

“…Meta-analysis was then performed using Revman 5.4 software to determine the significant risk factors for patients with stroke-related sarcopenia.ResultsA total of 14 studies (n = 3,113) were selected to determine the following factors that were statistically significant in patients with stroke-related sarcopenia: Age (OR = 1.04; 95% CI: 1.02, 1.06; P < 0.0001), tube feeding (OR = 3.98; 95% CI: 2.12, 7.47; P < 0.0001), pre-stroke sarcopenia (OR = 1.84; 95% CI: 1.39, 2.43; P < 0.0001), atrial fibrillation (OR = 1.53; 95% CI: 1.15, 2.02; P = 0.003), NIHSS score (OR = 1.48; 95% CI: 1.21, 1.81; P = 0.0001), and osteoporosis (OR = 1.801; 95% CI: 58, 2.04; P < 0.00001). …”
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Genotypic Spectrum in a Cohort of Sri Lankan Patients With Homocystinuria by Hewa Warawitage Dilanthi, Kandana Liyanage Subhashinie Jayasena, Nambage Dona Priyani Dhammika, Neluwa Liyanage Ruwan Indika, Matara Mahavidanage Nishani De Silva, Imalke Kankananarachchi, Pushpa Malkanthi Gardiye Punchihewa, Dharma Irugalbandara, Sabine Schroeder, Kosala Karunaratne, Eresha Jasinge

“…Among the 14 patients, the common clinical features were ectopia lentis (100%), intellectual disability (92%) and marfanoid features (78%) at presentation while three of them had developed osteoporosis (21%). Median age at diagnosis was 8 years (range 2–12). …”
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Evaluation of the effectiveness of the Iran-package of essential non-communicable disease (IraPEN) program in reducing cardiovascular disease risk in pilot areas by Somayeh Derakhshan, Davood Khalili, Alireza Mahdavi, Seyed-Saeed Hashemi-Nazari, Amir Kavousi, Fatemeh Hadavandsiri, Afshin Ostovar, Koorosh Etemad

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Protocol of a randomised trial of teriparatide followed by zoledronic acid to reduce fracture risk in adults with osteogenesis imperfecta by Jennifer Walsh, Catriona Keerie, Stuart H Ralston, Christopher J Weir, Muhammad K Javaid, WAYNE LAM, Bente L Langdahl, Jannie D Hald, Patricia Osborne

“…It is often treated with osteoporosis medications but their effectiveness at preventing fractures is unknown. …”
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Effects of Lemon Beverage Containing Citric Acid with Calcium Supplementation on Bone Metabolism and Mineral Density in Postmenopausal Women: Double-Blind 11-Month Intervention Stu... by Hiromi Ikeda, Tadayuki Iida, Masanori Hiramitsu, Takashi Inoue, Satomi Aoi, Miho Kanazashi, Fumiko Ishizaki, Toshihide Harada

“…A critical factor for preventing osteoporosis after menopause is attenuation of the accelerated turnover rate of bone metabolism. …”
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The Importance of the Prenyl Group in the Activities of Osthole in Enhancing Bone Formation and Inhibiting Bone Resorption In Vitro by Yuan-Kun Zhai, Ya-Lei Pan, Yin-Bo Niu, Chen-Rui Li, Xiang-Long Wu, Wu-Tu Fan, Ting-Li Lu, Qi-Bing Mei, Cory J. Xian

“…Osteoporosis treatment always aimed at keeping the balance of bone formation and bone resorption. …”
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Undernutrition risk and obesity increase the risk of osteosarcopenia in Mexican adults aged 50 and over: a prospective cohort study by Isabel Omaña-Guzmán, Ashuin Kammar-García, Luis Miguel Gutierrez-Robledo, Oscar Rosas-Carrasco

“…Osteosarcopenia is the coexistence of sarcopenia and osteopenia/osteoporosis and is related to higher morbidity and mortality. …”
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Reduction effect of oral pravastatin on the acute phase response to intravenous zoledronic acid: protocol for a real-world prospective, placebo-controlled trial by Qi Liu, Min Zhang, Liyuan Tao, Chunli Song, Haiyan Li, Gengyu Han, Runting Li, Dongwei Fan, Guohong Du, Dongyang Liu

“…Introduction Zoledronic acid (ZA) has been used as a first-line treatment in patients with osteoporosis (OP) who receive an annual injection of 5 mg. …”
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The Role of Microelements of Lumbar Disc Degeneration in Patients Undergoing Lumbar Spine Surgery by Sadiq R. Karkush, Manal K. Rasheed, Ali T. Abdul Wahid, Ahmed R. Majeed

“…Microelements are essential in bone metabolism and are associated with the prevention of osteoporosis and the alleviation of musculoskeletal pain. …”
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Effect of Mesenchymal Stem Cells and Platelet-Rich Plasma on the Bone Healing of Ovariectomized Rats by Bo Wei, Chengshuo Huang, Mingyan Zhao, Peng Li, Xiang Gao, Junchao Kong, Yanru Niu, Rui Huang, Juanhua Quan, Jinsong Wei, Jiaqi Chu

“…These results indicate that PRP treatment enhances bone microarchitecture in osteoporosis. Moreover, expression levels of osteogenesis-specific marker genes including RUNX2, OSX, and OPN were significantly upregulated in rats treated with PRP and BMSCs compared to those of other groups. …”
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Patterns of Comorbidity and Multimorbidity Among Patients With Multiple Sclerosis in a Large US Commercially Insured and Medicare Advantage Population by Dingwei Dai, Ajay Sharma, Amy L. Phillips, Carroline Lobo

“…Age-related and other comorbidities (ie, hypertension, hyperlipidemia, dyspepsia, osteoarthritis, osteoporosis, glaucoma, diabetes, cerebrovascular, cancer) were more common among patients 65 years and older Medicare Advantage (all _P_ < .0001). …”
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Correlation Between Objective Habit Metrics and Objective Medication Adherence: Retrospective Study of 15,818 Participants From Clinical Studies by Antoine Pironet, L Alison Phillips, Bernard Vrijens

“…These participants took part in 108 clinical studies mainly focused on treatments for hypertension (n=4737, 30%) and osteoporosis (n=3353, 21%). The SD of the hour of intake was significantly negatively correlated with the 2 objective adherence metrics: proportion of correct days (Spearman correlation coefficient, ρS=–0.62, P<.001) and proportion of doses taken (ρS=–0.09, P<.001). …”
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The Bony Density of the Pedicle Plays a More Significant Role in the Screw Anchorage Ability Than Other Regions of the Screw Trajectory by Zan Chen, Yue Chen, Jiajun Zhou, Yanwei He, Jingchi Li

“…ABSTRACT Objective Osteoporosis is a crucial risk factor for screw loosening. …”
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Clinical Characteristics of Aldosterone- and Cortisol-Coproducing Adrenal Adenoma in Primary Aldosteronism by Lu Tang, Xintao Li, Baojun Wang, Xin Ma, Hongzhao Li, Yu Gao, Liangyou Gu, Wenyuan Nie, Xu Zhang

“…Moreover, they had higher proportions of cardiovascular complications, glucose intolerance/diabetes, and osteopenia/osteoporosis compared to the pure APA patients (P<0.001). …”
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