Adipose-Derived Stem Cells Cocultured with Chondrocytes Promote the Proliferation of Chondrocytes by Jie Shi, Jiulong Liang, Bingyu Guo, Yu Zhang, Qiang Hui, Peng Chang, Kai Tao

“…Articular cartilage injury and defect caused by trauma and chronic osteoarthritis vascularity are very common, while the repair of injured cartilage remains a great challenge due to its limited healing capacity. …”
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Platelet-Rich Gel Supernatants Stimulate the Release of Anti-Inflammatory Proteins on Culture Media of Normal Equine Synovial Membrane Explants by Diana L. Ríos, Catalina López, Jorge U. Carmona

“…The cellular composition and the articular concentration (volume) of a platelet-rich plasma preparation could affect the anti-inflammatory and anabolic joint responses in horses with osteoarthritis.…”
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Alloreactivity of Allogeneic Mesenchymal Stem/Stromal Cells and Other Cellular Therapies: A Concise Review by Kiran Shah, Nirali Shah, Fatameh Ghassemi, Carolyn Ly, Teena George, Carla Lutz, Huseyin Sumer

“…Cellular therapies, deemed live medicine, have brought a wave of new generation biological therapies to treat previously untreatable diseases such as cancers and degenerative diseases like osteoarthritis. These cellular therapies have gained significant recognition in clinical research. …”
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Comparison of Functional Outcome of Total and Unicompartmental Knee Arthroplasty Using Computer-Assisted Patient-Specific Templating by Atef Mohamed Morsy, Emad Gaber Elbana, Ahmed Gaber Mostafa, Mark Ashraf Edward, Mahmoud A. Hafez

“…Only patients with medial compartmental osteoarthritis were included. KSS, functional knee score (FKS), and ROF were assessed preoperatively and at 6 months postoperatively. …”
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Medical cannabis in the management of musculoskeletal pain: a systematic review of clinical trials by Przemysław Płatek, Laura Piejko

“…Recent scientific findings suggest that cannabinoids may be therapeutically beneficial for conditions such as neurodegenerative disorders, seizures, nausea and vomiting, insomnia, neuropathic pain, excessive muscle tension, fibromyalgia, osteoarthritis (OA), rheumatoid arthritis (RA), and chronic wounds. …”
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Health-related quality of life, lifestyle habits and chronic pain in individuals with knee pain – a 2-year follow-up study by Charlotte Sylwander, Emma Haglund, Ingrid Larsson, Maria L. E. Andersson

“…Introduction Knee pain increases the risk of developing chronic widespread pain (CWP) and knee osteoarthritis (KOA). The prevalence of CWP and KOA has increased, and there is a need for early prevention. …”
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Thrombin Promotes Matrix Metalloproteinase-13 Expression through the PKCδ/c-Src/EGFR/PI3K/Akt/AP-1 Signaling Pathway in Human Chondrocytes by Chun-Yin Huang, Hsiu-Jung Lin, Hsin-Shui Chen, Shi-Yann Cheng, Horng-Chaung Hsu, Chih-Hsin Tang

“…Abnormalities in these processes are primary features of rheumatoid arthritis and osteoarthritis. Matrix metalloproteinase-13 (MMP-13) may contribute to the breakdown of articular cartilage during arthritis. …”
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Research of the Methylation Status of miR-124a Gene Promoter among Rheumatoid Arthritis Patients by Qiao Zhou, Li Long, Guixiu Shi, Jing Zhang, Tong Wu, Bin Zhou

“…DNA obtained from the frozen tissue of 7 RA samples, 6 osteoarthritis (OA) samples, and 3 healthy controls were undergoing bisulfite conversion and then analyzed for miR-124a promoter methylation using MSP assay. …”
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lncRNA DLEU1 Modulates Proliferation, Inflammation, and Extracellular Matrix Degradation of Chondrocytes through Regulating miR-671-5p by Xiangkun Wu, Shuai Yin, Lihua Yan, Yongxi Liu, Lilin Shang, Jun Liu

“…Long noncoding RNAs (lncRNAs) have been shown to be involved in the development of osteoarthritis. However, the expression, function, and mechanism of DLEU1 in OA development remain largely unclear. …”
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A meta-analysis of the effectiveness and side effects of hip arthroscopy and open surgical dislocation in the management of femoroacetabular impingement by Chenlie Ni, Haiqing Lin, Haibo Yin

“…Abstract Background The influence of femoroacetabular (FA) impingement has been implied in early hip osteoarthritis, particularly in young patients who enjoy athletics. …”
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RETURN TO SPORTS FOLLOWING KNEE OSTEOTOMY IN COMPETITIVE ATHLETES – CASE SERIES by Daniel Meirelles, Alexandre Carneiro Bitar, Caio D’Elia, Guilherme Garofo, Alberto Terrível, Wagner Castropil

“…Methods: Active athletes who underwent osteotomy or knee surgery to treat knee osteoarthritis were included, and their data was collected retrospectively. …”
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FEATURES HIP ARTHROPLASTY AFTER REDUCTIONRECONSTRUCTIVE INTERVENTIONS OF PROXIMAL FEMUR by B. Sh. Minasov, R. R. Yakupov, T. E. Hairov, I. R. Gafarov, K. K. Sirodzhov, K. K. Karimov, G. .N. Filimonov, A. R. Trubin

“…The control group consisted of 43 patients with idiopathic hip osteoarthritis who underwent primary arthroplasty. Results: conducting joint replacement in patients of the main group was accompanied by an increase in the frequency of intraoperative and postoperative complications. …”
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Cranial Cruciate Ligament Desmotomies in Sheep Resulting in Peroneus Tertius Injury by Peter J. Welsh, Crystal G. Collier, Holly M. Clement, Michael N. Vakula, Jeffrey B. Mason

“…Surgical destabilization of the stifle joint via cranial cruciate ligament desmotomy (CCLD) is a routine procedure for the study of osteoarthritis (OA). Traditionally performed in rats, rabbits, cats, and dogs, CCLD in sheep provides an opportunity to study the pathology and treatment of joint instability in a species whose stifle better represents the equivalent human femorotibial joint. …”
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The Potential of Menstrual Blood-Derived Mesenchymal Stem Cells for Cartilage Repair and Regeneration: Novel Aspects by I. Uzieliene, G. Urbonaite, Z. Tachtamisevaite, A. Mobasheri, E. Bernotiene

“…Articular cartilage is susceptible to traumas and degenerative diseases, such as osteoarthritis, and has poor self-regeneration capacity and therefore requires more effective therapeutic technique. …”
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Computed Tomography Analysis of Postsurgery Femoral Component Rotation Based on a Force Sensing Device Method versus Hypothetical Rotational Alignment Based on Anatomical Landmark... by Stefan W. Kreuzer, Amir Pourmoghaddam, Kevin J. Leffers, Clint W. Johnson, Marius Dettmer

“…Thirty-one patients underwent computer-navigated total knee arthroplasty for osteoarthritis with femoral rotation established via a force sensor. …”
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A3 Adenosine Receptor Allosteric Modulator Induces an Anti-Inflammatory Effect: In Vivo Studies and Molecular Mechanism of Action by Shira Cohen, Faina Barer, Sara Bar-Yehuda, Adriaan P. IJzerman, Kenneth A. Jacobson, Pnina Fishman

“…LUF6000 administration induced anti-inflammatory effect in 3 experimental animal models of rat adjuvant induced arthritis, monoiodoacetate induced osteoarthritis, and concanavalin A induced liver inflammation in mice. …”
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A scoping review of randomized trials assessing the impact of n-of-1 trials on clinical outcomes. by Joyce P Samuel, Susan H Wootton, Travis Holder, Donald Molony

“…<h4>Findings</h4>Twelve randomized trials of the n-of-1 approach were identified in conditions spanning chronic pain, osteoarthritis, chronic irreversible airflow limitation, attention-deficit hyperactivity disorder, hyperlipidemia, atrial fibrillation, statin intolerance, and hypertension. …”
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No Effect of Return to Sport Test Batteries with and without Psychological PROs on the Risk of a Second ACL Injury: A Critical Assessment of Four Different Test Batteries by Ramana Piussi, Rebecca Simonson, Johan Högberg, Roland Thomeé, Kristian Samuelsson, Eric Hamrin Senorski

“… # Design Retrospective Cohort study # Methods Patients' sex, age, height and weight, and the results of strength and hop tests, as well as answers to PRO's (including Tegner activity scale, the ACL Return to Sport after Injury scale (ACL-RSI) as well as the Quality of Life (QoL) subscale of the Knee injury and Osteoarthritis Outcome Score \[KOOS\]), were extracted from a rehabilitation-specific registry. …”
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Clinical Outcomes and Predictors of Patients with Fracture in Debre Markos Comprehensive Specialized Hospital, North West Ethiopia: A Prospective Cohort Study by Beminet Yimenu, Belayneh Mengist

“…The commonest complication was joint stiffness (45%) followed by osteoarthritis (21%). The risk of fracture-related complications among patients who did not visit traditional bone setter was decreased by 54% as compared to visitors (RR 0.46; 95% CI: (0.35, 0.60)) Conclusion. …”
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Biomechanical Characteristics on the Lower Extremity of Three Typical Yoga Manoeuvres by Elizabeth Whissell, Lin Wang, Pan Li, Jing Xian Li, Zhen Wei

“…However, knee injuries such as osteoarthritis (OA) should be considered because of the large knee extensor angle and adductor moments.…”
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